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701
A combined use of Panax ginseng extract and the probiotic, Lactobacillus plantarum in the diet of Asian seabass, Lates calcarifer: Effects on growth, immunity and survival after ba...
Published 2025-03-01“…The highest activity of Superoxide dismutase (5.44 ± 0.62 U/mg), catalase (15.68 ± 1.04 U/mg) and glutathione peroxidase (14.5 ± 2.4 U/mg) was observed in LAC-P + GINS (1 %) treatment (P < 0.01). …”
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702
The Role of Potassium Phosphite in Enhancing the Activity of Defense Enzymes in Rice Infected by Sheath Blight
Published 2024-11-01“…The leaf extract was then obtained to measure enzyme activity, including catalase (CAT), polyphenol oxidase (PPO), and superoxide dismutase (SOD). Disease severity and enzyme activity were studied in a factorial design using a completely randomized design with two cultivars, Tarom (resistant) and Khazar (susceptible), and two treatments of potassium phosphite and R. solani, each with three replications. …”
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703
Dietary steviol glycosides mixture supplementation modulates the gene expression of gut chemoreceptors and enhances the antioxidant capacity in weaned piglets
Published 2025-02-01“…Increasing the concentration of SGs mixture linearly and quadratically increased serum total superoxide dismutase (T-SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activity, as well as hepatic T-SOD, GSH-Px activity, and muscle total antioxidant capacity contents (P < 0.05). …”
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704
Positive effects of optimal dietary protein content on the growth, reproductive performance and health of Procambarus clarkii broodstock farming in rice field
Published 2025-03-01“…The activity of total superoxide dismutase, catalase, glutathione peroxidase, and lysozyme peaked in the P31 group and was significantly higher than in the P43 group (P < 0.05). …”
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705
Effect of the Iridoid-rich Fraction from <italic>Valeriana jatamansi</italic> Jones on Oxidative Stress in Rats with Spinal Cord Injury
Published 2019-06-01“…The rats were sacrificed on third days after administration, and the contents of oxidative stress indexes superoxide dismutase(SOD)and malondialdehyde(MDA)in serum were detected by enzyme linked immunosorbent assay(ELISA); the related biochemical kit was used to test glutathione peroxidase(GSH-PX)and catalase(CAT)viability of the spinal cord tissue; the expression levels of apoptosis-related proteins of Caspase-3, B cell lymphoma(Bcl-2)associated X protein(Bax), and Bcl-2 were detected by Western blot; and the Hematoxylin/eosin(HE)staining was used to observe the pathological changes of the spinal cord tissue at the perilesional area; and Terminal-deoxynucleoitidyl transferase mediated nick end labeling(TUNEL)was used to observe the apoptosis of nerve cells of the spinal cord tissue at the perilesional area.Results:The results of ELISA showed that compared with the sham-operated group, the SOD content in the serum of the model group decreased, and the MDA content increased; compared with the model group, the SOD content in the serum of the treatment group with iridoid-rich fraction from <italic>Valeriana jatamansi</italic> Jones increased significantly(<italic>P</italic>< 0.05), and the MDA content decreased significantly(<italic>P</italic>< 0.01). …”
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706
Optimizing selenium-enriched yeast supplementation in laying hens: Enhancing egg quality, selenium concentration in eggs, antioxidant defense, and liver health
Published 2025-01-01“…Antioxidant capacity of the birds were significantly enhanced due to dietary supplementation of SY as indicated by increased serum levels of total antioxidant capacity, and activities of catalase, glutathione peroxidase, and superoxide dismutase (P < 0.05). Analysis of hepatic genes expression revealed that SY15 supplementation significantly upregulated key antioxidant-related genes (Nrf2, HO-1, CAT, and NQO1) and downregulated Keap1 expression (P < 0.05), suggesting strong activation of the antioxidant defense system. …”
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707
Phosphorus-solubilizing fungi promote the growth of Fritillaria taipaiensis P. Y. Li by regulating physiological and biochemical reactions and protecting enzyme system–related gene...
Published 2025-01-01“…The activities of peroxidase (POD), superoxide dismutase (SOD), and catalase (CAT) were higher in all inoculation groups than those in the CK group; the changes in SOD and CAT activities were significant (P < 0.05). …”
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708
Pharmacological ascorbate combined with rucosopasem selectively radio-chemo-sensitizes NSCLC via generation of H2O2
Published 2025-03-01“…Pentaazamacrocyclic Mn (II)-containing (MnPAM) superoxide dismutase (SOD) mimetics and pharmacological ascorbate given IV to achieve [mM] plasma levels (pharmacological ascorbate: P-AscH‾) have been shown to act individually as cancer cell radio- and chemosensitizers via the generation of H2O2 in vivo. …”
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709
Effect of Berberine on the Inflammatory Response of ANA-1 Cells Induced by Angiotensin Ⅱ Based on TLR4 Signaling Pathway
Published 2022-04-01“…Cell proliferation and toxicity test (CCK-8) was used to detect the effect of different concentrations of BBR on cell viability; the flow cytometry was used to detect the mean fluorescence intensity (MFI) of TLR4 on cell membrane ; ELISA method was used to detect the content of interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α); the real-time quantitative PCR was used to detect the mRNA level of IL-1β, IL-6, TNF-α; Western blot was used to detect the phosphorylation of p-ERK/ERK, p-p38/p38, p-JNK/JNK, p-p65/p65 and p-IRF3/IRF3 and the expression of TLR4, MyD88 and AP-1; the biochemical assay was used to detect the content of malondialdehyde (MDA) and the activity of superoxide dismutase (SOD).Results① CCK-8 assay results: compared with the control group, there was no significant difference in cell activity of the low, medium and high- dose BBR group, the difference was not statistically significant (<italic>P</italic>>0.05). ② Flow cytometry results: compared with the fluorescent antibody group, MFI of the model group was significantly decreased; compared with the model group, MFI of the model group + the high dose BBR group was significantly increased, the difference was statistically significant (<italic>P</italic><0.05). ③ ELISA results: compared with the control group, the content of IL-1β, IL-6, TNF- α of the model group was significantly increased; compared with the model group, the content of IL-1β, IL-6, TNF- α of the model group + the low, medium and high dose BBR group was significantly decreased, the difference was statistically significant (<italic>P</italic><0.05). ④ Real-time quantitative PCR results: compared with the control group, the mRNA level of IL-1β, IL-6, TNF-α of the model group was significantly increased; compared with the model group, the mRNA level of IL-1β, IL-6, TNF- α of the model group + the low, medium and high-dose BBR group was significantly decreased, the difference was statistically significant (<italic>P</italic><0.05). ⑤ Western blot results: compared with the control group, the phosphorylation expression of p65 and IRF-3 protein of the model group after intervention for 45 minutes was significantly increased, and the phosphorylation expression of p65, IRF-3 protein in the model group + the low, medium and high-dose BBR group was significantly decreased. …”
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710
Exploring the potential of an oyster (Saccostrea mordax) in oligotrophic seas: Effects of starvation on physiological and molecular regulation
Published 2025-03-01“…A significant decrease in oyster respiration rate was observed from the 14th day, and on the 90th day, the activities of Superoxide dismutase (SOD) and Catalase (CAT), and the content of Malondialdehyde (MDA) in the gill of oyster decreased. …”
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711
2-Cys Peroxiredoxins: Emerging Hubs Determining Redox Dependency of Mammalian Signaling Networks
Published 2014-01-01“…Mammalian cells have a well-defined set of antioxidant enzymes, which includes superoxide dismutases, catalase, glutathione peroxidases, and peroxiredoxins. …”
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712
Endophytes: Colonization, Behaviour, and Their Role in Defense Mechanism
Published 2020-01-01“…However, they have to survive the oxidative environments, and endophytes like Enterobacter sp. encode superoxide dismutases, catalases, and hydroperoxide reductases to cope up the oxidative stress during colonization. …”
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713
Exposure of cerebellar granule cells to nanosilver: Oxidative stress parameters and the protective effect of exogenous glutathione
Published 2024-10-01“…As oxidative stress (OS) is known to be one of the major mechanisms of AgNP-induced toxicity, in the present study, we have evaluated OS-related changes in cytotoxicity parameters in AgNP-treated cerebellar granule cells (CGCs), as well as the effectiveness of antioxidant defence systems, such as glutathione (GSH), superoxide dismutases (SOD1 and SOD2) and catalase. The results indicate that exposure of CGCs to AgNPs decreases cell viability and mitochondrial potential and increases intracellular calcium concentration and free radical production. …”
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714
Muscular TOR knockdown and endurance exercise ameliorate high salt and age-related skeletal muscle degradation by activating the MTOR-mediated pathway.
Published 2025-01-01“…The results showed that muscle TOR knockdown and endurance exercise significantly increased the climbing speed, climbing endurance, the expression of autophagy related gene 2(ATG2), silent information regulator 2(SIR2), and pparγ coactivator 1(PGC-1α) genes, and superoxide dismutases(SOD) activity, but it decreased the expression of the TOR gene and reactive oxygen species(ROS) level, and it protected the myofibrillar fibers and mitochondria of skeletal muscle in Drosophila on a high-salt diet. …”
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715
Effect of thymol and propolis extract on genotoxicity, biochemical activities and expression profile of some genes on honey bee, Apis mellifera, infected with Vairimorpha (Nosema)...
Published 2025-01-01“…The collected samples were used in studying the genotoxicity effect, the concentration of oxidative enzymes (superoxide-dismutases, glutathione S transferase, catalase and malondialdehyde (MDA)), measuring the relative expression of antimicrobial genes and hypopharyngeal glands genes major royal proteins 1 & 2 (MJRP1 and MJRP2). …”
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716
Alterations in mRNA level of proteins related to redox state and mitochondria in an Alzheimer’s disease animal model: Promising targets in neuroprotection
Published 2024-10-01“…This study aimed to determine the expression of genes encoding superoxide dismutases (SOD1, SOD2), poly(ADP-ribose) polymerases (PARPs) and sirtuins (SIRTs). …”
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