The Eczema Bathing Study: Weekly versus daily bathing for people with eczema? Protocol of an online, randomised controlled trial [version 2; peer review: 1 approved, 2 approved wit... by Paul Leighton, Wei Chern Gavin Fong, Ingrid Muller, Laura Howells, Arabella Baker, Eleanor J Mitchell, Eleanor Harrison, Leila Thuma, Yimin Jiang, Lucy Bradshaw, Alan Montgomery, Fiona Cowdel, Matthew J Ridd, Jane Ravenscroft, Reiko J Tanaka, Miriam Santer, Richard Swinden, Nicholas Hilken, Carron Layfield, Richard Dooley, Sophia Collins, Clare Upton, Tracy Owen, Firoza Davies, Devin Patel, Mars Eddis-Finbow, Hywel C Williams, Goldie Putrym, Kim S Thomas, Amanda Roberts

“…A sample of participants will also be invited to a semi-structured interview to discuss their experience. The primary comparative analysis will be according to randomised allocation regardless of actual frequency of bathing. …”
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Annotation and characterization of immunoglobulin loci and CDR3 polymorphism in water buffalo (Bubalus bubalis) by Yunlan Deng, Fengli Wu, Fengli Wu, Qianqian Li, Lidie Yao, Chengzhi Yang, Long Ma, Xinsheng Yao, Jun Li

“…Annotation criteria included functional motifs, RSS sequences, and structural features of V, D, J, and C genes. The CDR3 repertoires were constructed using genomic DNA extracted from spleen samples of five healthy buffaloes. …”
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Humanizing processes after harm part 1: patient safety incident investigations, litigation and the experiences of those affected by Lauren Ramsey, Laura Sheard, Justin Waring, Siobhan McHugh, Ruth Simms-Ellis, Ruth Simms-Ellis, Gemma Louch, Katherine Ludwin, Jane K. O’Hara

“…Nonetheless, there remains little UK-based evidence exploring how this relates to the experiences of those affected over time, including the factors influencing decisions to litigate.AimsWe aimed to explore the experiences of patients, families, staff and legal representatives affected by safety incidents over time, and the factors influencing decisions to litigate.MethodsParticipants were purposively recruited via (i) communication from four NHS hospital Trusts or an independent national investigator in England, (ii) relevant charitable organizations, (iii) social media, and (iv) word of mouth to take part in a qualitative semi-structured interview study. Data were analyzed using an inductive reflexive thematic approach.Findings42 people with personal or professional experience of safety incident investigations participated, comprising patients and families (n = 18), healthcare staff (n = 7), legal staff (n = 1), and investigators (n = 16). …”
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Impact of dietary mulberry (Morus alba) fruit extract on the growth performance, skin color, and immune response of fancy carp (Cyprinus carpio) by Wassana Prisingkorn, Prasoborn Rinthong, Narong Kamolrat, Pattama Wiriyapattanasub, Sutee Wongmaneeprateep, Jariyavadee Suriyaphan, Apichet Pholoeng, Eakapol Wangkahart

“…Liver histology revealed a normal structure across all groups, indicating no adverse effects from the diets, including those with mulberry supplementation. …”
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Analysis of the Effect of Human Type I Collagen-Derived Peptide on Bone Regenerative Capacity and Comparison with Various Collagen Materials In Vivo by Tatsunori Asakura, Tran Thi Thuy Diep, Yuta Ueda, Aoi Yamada, Takahiro Tsuzuno, Naoki Takahashi, Masayuki Miyata, Koichi Tabeta, Masaki Nagata, Ken Matsuda

“…Biomimetic materials that replicate the body’s microscopic structure, such as Cellnest^®, are gaining attention. …”
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Automated method of bronchus and artery dimension measurement in an adult bronchiectasis population by Angelina L.P. Pieters, Qianting Lv, Jennifer J. Meerburg, Tjeerd van der Veer, Eleni-Rosalina Andrinopoulou, Pierluigi Ciet, James D. Chalmers, Michael R. Loebinger, Charles S. Haworth, J. Stuart Elborn, Harm A.W.M. Tiddens

“…The aim of this study was three-fold: 1) to assess bronchus–artery (BA) dimensions using fully automated software in a cohort of BE disease patients; 2) to compare BA dimensions with semi-quantitative BEST-CT (Bronchiectasis Scoring Technique for CT) scores for BE and bronchial wall thickening; and 3) to explore the structure–function relationship between BA-method lumen dimensions and spirometry outcomes. …”
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<i>Sambucus nigra</i>-Lyophilized Fruit Extract Attenuated Acute Redox–Homeostatic Imbalance via Mutagenic and Oxidative Stress Modulation in Mice Model on Gentamicin-Induced Nephr... by Kamelia Petkova-Parlapanska, Ivaylo Stefanov, Julian Ananiev, Tsvetelin Georgiev, Petya Hadzhibozheva, Veselina Petrova-Tacheva, Nikolay Kaloyanov, Ekaterina Georgieva, Galina Nikolova, Yanka Karamalakova

“…<b>Conclusions:</b> Histological evaluation confirmed that <i>S. nigra</i> (120 mg kg⁻¹) attenuated renal dysfunction and structural damage by modulating oxidative stress and acute inflammation and could be used as an anti-fibrotic alternative in GM nephrotoxicity.…”
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Admission outcomes and their associated factors among children admitted to the paediatric emergency unit within 24 hours of Dilla University Referral Hospital, Ethiopia, 2023: a cr... by Binyam Tariku Seboka, Tomas Yeheyis, Yihenew Ayehu Dessie, Samuel Jigso Dube, Abel Desalegn Demeke, Mekdes Mekonnen Feleke, Abdo Hajo Jarso, Asresu Feleke Bati, Etaferaw Udo, Selam Tadele Markos, Chalachew Kassaw, Amdehiwot Aynalem Debebe, Ephrem Geja Gechere

“…A total of 885 complete charts of the children aged 29 days to 14 years were analysed. Structured checklist was used for data collection. STATA V.14 was used for data analysis. …”
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Do community-based digital health inclusion programmes contribute to tackling health inequalities in disadvantaged population groups?: a qualitative study of experiences of a city-... by Shoba Poduval, Lily Arnold, Emma Carta, Danielle Nimmons, Irene Stratton, Michael Shaw, Katherine Bradbury, Fiona Stevenson

“…Methods We used qualitative semi-structured interviews to explore the experiences of service-users receiving digital support, and perspectives of staff working for organisations coordinating or providing digital support (n = 30). …”
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Acute enteritis with pelvic SBRT: Influence of bowel delineation methods by Akshay Dinesan, Maneesh Singh, Prachi Mehta, Priyamvada Maitre, Vedang Murthy

“…Objectively, the volume of the bowel structures receiving 7 Gy, 14 Gy, and 25 Gy did not show any statistically significant difference between cases and controls. …”
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Eco-benign synthesis of multifunctional silver nanoparticles using leptochloa fusca for enhanced biomedical and catalytic applications by Riaz Ahmad Khan, Hidayat Ullah Khan, Shahnaz, Kamran Tahir, Moamen S Refat, Abdel Majid A Adam, Amnah Mohammed Alsuhaibani

“…This type of binding results in conformational changes in ssDNA and BSA structures and therefore LF-AgNPs hold potential for numerous applications like drug delivery, anticancer agents and receptor targeting. …”
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Boosting electrocatalytic generation of FDCA and H2 from 2,5-furanedimethanol solution by carbonized wood supported Fe-CoP nanoleaves by Yuan Ma, Jiaojiao Miao, Yuanyuan Li, Xuehua Zhou, Lianbing Zhang, Jian Zhang, Guanglei Li, Yong Qin, Jie Gao

“…Wood serves as an ideal matrix for boosting the performance of catalysts, since its hierarchical porous structures facilitate mass transport and provide abundant active sites. …”
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Exploring the relationship between mental health issues and academic performance of undergraduate students in a Ghanaian tertiary institution: a cross-sectional study by Andrew Nketsia Arthur, Joanne Fraikue, Bijoux Adu-Amankwah, Richard Ofori, Dorcas Sekyi, Abena Afrakomah Boateng, Elsie Asamoah, Seth Christopher Yaw Appiah

“…Through the multistage sampling technique, structured questionnaires were administered to 384 undergraduate students at Kwame Nkrumah University of Science and Technology (KNUST). …”
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High-Performance Hydrogen Sensing at Room Temperature via Nb-Doped Titanium Oxide Thin Films Fabricated by Micro-Arc Oxidation by Chilou Zhou, Zhiqiu Ye, Yue Tan, Zhenghua Wu, Xinyi Guo, Yinglin Bai, Xuying Xie, Zilong Wu, Ji’an Feng, Yao Xu, Bo Deng, Hao Wu

“…The enhanced hydrogen sensing mechanism of NTO thin films primarily stems from the influence of Nb₂O₅; nanoparticles doping in the anatase-phase TiO₂ structure on the semiconductor surface depletion layer, as well as the improved charge transfer and additional adsorption sites provided by the Nb/Ti composite metal oxides, such as TiNb₂O₇ and Ti_0.95Nb_0.95O₄. …”
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The use of patient-generated health data in the management of low anterior resection syndrome: a qualitative study by Olivia Monton, Olivia Monton, Allister Smith, Sarah Sabboobeh, Marie Demian, Julie Cornish, Steven D. Wexner, Peter Christensen, Peter Christensen, Amandeep Ghuman, Liliana G. Bordeianou, Liliana G. Bordeianou, Liliana G. Bordeianou, Celia Keane, Celia Keane, Syed Husain, Alessandra Gasior, Alessandra Gasior, Natalie Leon, Julie Savard, Lieba R. Savitt, Margit Majgaard, Gitte Kjær Sørensen, Melanie Mills, Fateme Rajabiyazdi, Marylise Boutros, Marylise Boutros

“…We conducted individual semi-structured interviews with these experts between August 2022 and February 2024. …”
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Individualized diagnosis of Parkinson’s disease based on multivariate magnetic resonance imaging radiomics and clinical indexes by Qianqian Ye, Chenhui Lin, Fangyi Xiao, Tao Jiang, Jialong Hou, Yi Zheng, Jiaxue Xu, Jiani Huang, Keke Chen, Jinlai Cai, Jingjing Qian, Weiwei Quan, Yanyan Chen

“…Radiomics features were extracted from structural MRI (T1WI and T2-FLair). Support Vector Machine (SVM) classifiers were developed using MRI radiomics data from both monomodal and multimodal radiomics models. …”
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Eco-friendly alginate/PCL-TiO2 hybrid biocomposites: Preparation, properties, and methylene blue photodegradation by Bunga Fisikanta Bukit, Agus Wedi Pratama, Erna Frida, Bakti Berlyanto Sedayu, Dina Fransiska, Deni Purnomo, Emma Rochima, Istiqomah Rahmawati, Sona Suhartana, Firda Aulya Syamani

“…XRD analysis of the composites PA, PA-Ti1, PA-Ti3, and PA-Ti5 revealed an orthorhombic to tetragonal semicrystalline structure after added TiO2. FT-IR spectroscopy show sharp peak at 1721 cm⁻¹ represents C = O vibration, while characteristic CH stretching vibrations of PCL are evident at 2800–2900 cm-1. …”
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Dietary diversity and its associated factors among school children in conflict affected communities of southern Ethiopia by Tagese Yakob, Eskinder Israel, Begidu Yakob, Mekdes Meshesha, Endale Jambo, Tadewos Utalo, Awoke Abraham

“…The data were collected by using a structured questionnaire. The data were collected and entered into Epi-data version 4.6.0.2 and exported to STATA software version 14 for analysis. …”
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Comparing physician associates and foundation year two doctors-in-training undertaking emergency medicine consultations in England: a mixed-methods study of processes and outcomes by Simon de Lusignan, Mary Halter, Carly Wheeler, Laura Nice, Sally Brearley, James Ennis, Jonathan Gabe, Heather Gage, Phil Begg, Chao Wang, Jim Parle, Vari Drennan

“…Objectives To compare the contribution of physician associates to the processes and outcomes of emergency medicine consultations with that of foundation year two doctors-in-training.Design Mixed-methods study: retrospective chart review using 4 months’ anonymised clinical record data of all patients seen by physician associates or foundation year two doctors-in-training in 2016; review of a subsample of 40 records for clinical adequacy; semi-structured interviews with staff and patients; observations of physician associates.Setting Three emergency departments in England.Participants The records of 8816 patients attended by 6 physician associates and 40 foundation year two doctors-in-training; of these n=3197 had the primary outcome recorded (n=1129 physician associates, n=2068 doctor); 14 clinicians and managers and 6 patients or relatives for interview; 5 physician associates for observation.Primary and secondary outcome measures The primary outcome was unplanned re-attendance at the same emergency department within 7 days. …”
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Proteogenomic annotation of T6SS components identified in Bacteroides fragilis secretome by Natalya B. Zakharzhevskaya, Olga Yu Shagaleeva, Daria A. Kashatnikova, Daria A. Kashatnikova, Anton O. Goncharov, Anton O. Goncharov, Daria V. Evsyutina, Dmitry A. Kardonsky, Elizaveta A. Vorobeva, Artemiy S. Silantiev, Viktoria D. Kazakova, Irina V. Kolesnikova, Ivan O. Butenko, Anna A. Vanyushkina, Svetlana V. Smirnova, Andrei V. Chaplin, Andrei V. Chaplin, Boris A. Efimov, Boris A. Efimov

“…Intensive study of the T6SS structure has led to an understanding of certain issues related to its functional activity, but the exact regulatory mechanisms of E-I protein pair activity remain unclear. …”
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