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44861
Quantitative Changes in Vascular and Neural Fibers Induced by Subretinal Fluid Excluding the Peripapillary Region in Patients with Chronic Central Serous Chorioretinopathy
Published 2025-01-01“…<b>Conclusions:</b> Chronic SRF in CSCR patients, even when not involving the peripapillary region, leads to significant structural changes in both the neural and vascular components of the retina. …”
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44862
Emerging roles of mitochondrial sirtuin SIRT5 in succinylation modification and cancer development
Published 2025-01-01“…This review aims to provide a comprehensive overview of the current research status of SIRT5. We discuss its structural characteristics and regulatory mechanisms, compare its functions with other sirtuin family members, and elucidate the mechanisms regulating SIRT5 activity. …”
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44863
Formation of the Figge Maar Seafloor Crater During the 1964 B1 Blowout in the German North Sea
Published 2022-12-01“…Although seafloor craters formed by fluid flow are very common structures, little is known about their formation dynamics. …”
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44864
A missense variant in the SOX5 gene (c.221C > T) is associated with intellectual disability
Published 2025-02-01“…Additionally, protein stability was evaluated using I-Mutant, and 3D protein structures were modeled with I-TASSER. Western blots and QPCR were employed to assess gene expression and protein stability. …”
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44865
Genetic Diversity of <i>Diaphorina citri</i> and Its Endosymbiont Across Diffusion Frontier and Epidemic Areas of Citrus Huanglongbing in China
Published 2025-01-01“…To understand the genetic diversity and population structure of <i>D. citri</i> in the context of HLB diffusion, we analyzed 13 populations from the HLB diffusion frontier and 25 populations from epidemic areas in China. …”
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44866
Acupuncture mediates the “gut–testis axis” to improve asthenozoospermia
Published 2025-01-01“…In addition, gut microbiome and metabolomics were used to study the impact of acupuncture on the gut microbiota structure, serum, and testicular metabolites in asthenozoospermic mice. …”
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44867
Features and evolutionary adaptations of the mitochondrial genome of Garuga forrestii W. W. Sm
Published 2025-01-01“…The study also investigates RNA editing sites and evolutionary patterns.ResultsThe mitochondrial genome exhibits a low proportion of repetitive sequences (3.30%), suggesting a highly conserved structure. A high copy number of the trnM-CAT gene (4 copies) is noted, which may contribute to genomic rearrangement and adaptive evolution. …”
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44868
Distinct subcellular localization of tau and alpha-synuclein in lewy body disease
Published 2025-01-01“…In the rare cases pathologic α-syn and pathologic tau were found in the same Lewy body or Lewy neurite, tau appeared to surround α-syn but did not colocalize within the same structure. The relationship between tau and α-syn copathology is important for explaining clinical symptoms, severity, and progression, but there is no evidence for frequent, direct protein-protein interactions in the middle temporal gyrus.…”
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44869
The interplay between sex, lifestyle factors and built environment on 20-year cardiovascular disease incidence; the ATTICA study (2002–2022)
Published 2025-01-01“…Multivariate analyses, including generalized structural equation modeling (GSEM), revealed that the impact of the urban built environment on the long-term (20-year) CVD risk is mediated by lifestyle-related risk factors.ConclusionUrban inhabitants exhibit a higher long-term CVD incidence compared to their rural counterparts, which was partially explained by their lifestyle behaviors. …”
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44870
Experimental study of partially oxidized sodium alginate gel combined with myogenic stem cells to improve cardiac function in aged rats with myocardial infarction
Published 2025-01-01“…[Methods] The models of myocardial infarction in aged rats were established by ligating the coronary arteries and divided randomly into the group of saline control group, sodium alginate group, myogenic stem cells group and sodium alginate combined with myogenic stem cells group(joint group), each had 30 rats.The same amount of corresponding material was injected into the myocardial infarction area of rats in each group respectively.The cardiac structure and function of the rats were evaluated by echocardiography 8 weeks after the operation, and then the rats were executed.The hearts were removed to observe the differences in ventricular remodeling by histological analysis and the angiogenesis and collagen secretion of the ventricular slices were further analyzed. …”
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44871
Central Pain in Parkinson’s Disease: Behavioral and Cognitive Characteristics
Published 2021-01-01“…Material and Methods. A structured interview was used to identify and characterize pain in a cohort of 260 consecutive PD patients. …”
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44872
Eco-friendly synthesis of chitosan NPs from Fioria vitifolia (L.) L: Potential to antibacterial, antioxidant, cytotoxicity properties of HepG2 cells and their evaluation of safety...
Published 2025-03-01“…The XRD pattern showed prominent peaks at 2θ locations, confirming the hexagonal wurtzite structure. EDX was analysis confirmed the presence of chitosan in crystalline form for synthesized nanoparticle. …”
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44873
Encoding of cerebellar dentate neuron activity during visual attention in rhesus macaques
Published 2025-01-01“…To better understand the heterogeneous relationship between task structure, behavioral performance, and neural dynamics, we constructed a behavioral, an encoding, and a decoding model. …”
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44874
Reasons for Undesirable Pregnancy Outcomes among Women with Appendicitis: The Experience of a Tertiary Center
Published 2020-01-01“…In addition to the demographic structure of the patients, surgical technique, the number of pregnancies, multiple pregnancy status, surgical pathologies, laboratory values, radiological imaging methods, and length of hospital stay were evaluated. …”
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44875
Evaluation of Melongosides as Potential Inhibitors of NS2B-NS3 Activator-Protease of Dengue Virus (Serotype 2) by Using Molecular Docking and Dynamics Simulation Approach
Published 2022-01-01“…However, the 200 ns molecular dynamic simulation experiment indicates significant stability of the protein-ligand interactions with the RMSD values of 2.5 Å, thus suggesting a better docking position and no disruption of the protein-ligand structure. Taken together, melongosides need further attention for more scientific studies as a DENV inhibitory agent, which if proven, in vivo and in clinical trials, can be a useful therapeutic agent against at least DENV-2.…”
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44876
Olfactory Impairment and Recovery in Zebrafish (<i>Danio rerio</i>) Following Cadmium Exposure
Published 2025-01-01“…The research aimed to assess structural and functional changes in the zebrafish’s olfactory lamellae, providing a deeper understanding of how cadmium affects the sense of smell in this aquatic species. …”
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44877
Assessing Knowledge, Attitudes, and Practices of Healthcare Workers regarding Biomedical Waste Management at Biyem-Assi District Hospital, Yaounde: A Cross-Sectional Analytical Stu...
Published 2020-01-01“…Variables of interest were knowledge, attitudes, and practices of the respondents. A structured and pretested questionnaire was used for data collection. …”
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44878
THE EFFECTIVENESS OF ZINC AND RISEDRONATE ON BONE TURNOVER IN RAT MODEL OF OSTEOPOROSIS ASSESSED WITH THE EXPRESSION OF β-CROSSLAPS
Published 2019-12-01“…Previous research in rat model osteoporosis, Zinc have a potential effect to prevent and rebuild bone structure with osteoblast stimulation in bone formation and osteoclast activity inhibition in bone resorption by increasing Osteoprotegerin production, that inhibit bond between RANKL and RANK. …”
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44879
Biomarkers of racism-based stress injury: A feasibility and correlation study
Published 2025-01-01“… Abstract Background: Persistent discrimination and identity threats contribute to adverse health outcomes in minoritized groups, mediated by both structural racism and physiological stress responses. …”
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44880
Effects of hypoxia on the heart of the juvenile four-finger threadfin (Eleutheronema tetradactylum) based on physiological indicators and transcriptome analysis
Published 2025-02-01“…Histological analysis revealed structural damage in myocardial fibers under hypoxia, with increasing severity over time. …”
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