The use of antimicrobials in Italian buffalo farms by Gabriele Di Vuolo, Federico Scali, Claudia Romeo, Valentina Lorenzi, Chiara D. Ambra, Maria Serrapica, Giovanna Cappelli, Francesca Fusi, Esterina De Carlo, Giovanni Loris Alborali, Luigi Bertocchi, Domenico Vecchio

“…The identification of the principal causes of AMU in buffalo represents an important step towards a more efficient AMU analysis of structural and management critical aspects connected to the buffalo breeding system finalized to reduce to sustainable mode the AMU, in particular critical antimicrobials, and their connected AMR. …”
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Comparison of clinical and virological features in pediatric and adult dengue cases at Insein General Hospital during Myanmar’s 2022 dengue season by Htin Lin, Mya Myat Ngwe Tun, Yin Mon Wint Zin, Khin Theingi Myint, Win Kay Khine, Khine Mya Nwe, Aye Aye Thant, Thin Thin Shwe, Win Mar, Khin Sandar Aye, Khaing Moe Aung, Yuki Takamatsu, Wah Wah Aung, Yi Yi Kyaw, Takeshi Urano, Kouichi Morita, Hlaing Myat Thu

“…Results The dengue non-structural protein-1 antigen (NS1Ag) positivity was 37% in children and 32% in adults. …”
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The work-related well-being of social service workers post COVID-19 pandemic: The psychosocial impact of remote vs in-person work by Venusia COVELLI, Morena TAFFARELLO, Marina Angela VISCO, Francesco CHIRICO, Pietro CRESCENZO, Luca COPPETA, Kavita BATRA, Alessandra MARELLI

“…Methods: SSW working in social service delivery organizations were recruited to participate in an online semi-structured survey comprising the Job Satisfaction Scale, Psychological General Well-Being Index-S, Work-Related Stress Indicator Tool, Organizational Identification Scale, and Positive and Negative Affect Schedule. …”
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The Middle to Late Triassic of Central Saudi Arabia with emphasis on the Jilh Formation. Part I: lithostratigraphy, facies and paleoenvironments, palaeontology and biostratigraphic... by Le Nindre, Yves-Michel, Vaslet, Denis, Vrielynck, Bruno, Krystyn, Leopold, Manivit, Jacques, Memesh, Abdullah, Davies, Roger Brett

“…Part II “Sequence stratigraphy, depositional and structural evolution, and regional correlations” exploits the results of Part I, providing a dynamic reconstruction and a renewed vision of the Middle to Late Triassic at the regional scale.The Jilh Formation at outcrop consists of a multilayer system of thinly bedded, mixed siliciclastics with subordinate carbonates and evaporites, representing non-marine to offshore settings. …”
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Investigating the impact of microbiome-changing interventions on food decision-making: MIFOOD study protocol by Meghedi Vartanian, Konrad Jakob Endres, Yee Teng Lee, Silke Friedrich, Marie-Theres Meemken, Imke Schamarek, Kerstin Rohde-Zimmermann, Robin Schürfeld, Lina Eisenberg, Anja Hilbert, Frauke Beyer, Michael Stumvoll, Julia Sacher, Arno Villringer, Julia F. Christensen, A. Veronica Witte

“…Secondary outcome measures include structural MRI, eating habits, lifestyle factors, personality traits, and mood. …”
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Combination of the endoscopic septonasal flap technique and bioabsorbable steroid-eluting stents for repair of congenital choanal atresia in neonates and infants: a retrospective s... by Peng-peng Wang, Li-xing Tang, Jie Zhang, Xiao-jian Yang, Wei Zhang, Yang Han, Xiao Xiao, Xin Ni, Wen-tong Ge

“…Conclusions The endoscopic septonasal flap technique can effectively expose and expand the choanal bony structure for repair of congenital choanal atresia in neonates and infants. …”
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Fermented sugarcane juice-derived probiotic Levilactobacillus brevis RAMULAB54 enhances lipid metabolism and glucose homeostasis through PPAR-γ activation by V. B. Chandana Kumari, Ramith Ramu, Sujay S. Huligere, Shashank M. Patil, Shivasharanappa Nayakvadi, Sharath Bijoor, Uma Venkateswaran Manjappara, Mohammad Z. Ahmed, Ling Shing Wong

“…Histopathology showed improved tissue structure, indicating LB13243's potential to reduce hyperglycemia and hyperlipidemia by modulating lipid metabolism and inflammation. …”
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Exploring the role of district clinical specialist teams in maternal health outcomes in a South African district: A mixed method study from 2012 to 2020 by J Basu, A Stewart, D Basu, J Wing, U Feucht

“…A review of DCST reports and documents was conducted along with in-person structured interviews among health professionals and district health managers in the Ekurhuleni Health District in SA. …”
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Evaluating the World Health Organization’s Hearts Model for Hypertension and Diabetes Management: A Pilot Implementation Study in Guatemala by Irmgardt Alicia Wellmann, Luis Fernando Ayala, Taryn M. Valley, Vilma Irazola, Mark D. Huffman, Michele Heisler, Peter Rohloff, Rocío Donis, Eduardo Palacios, Manuel Ramírez-Zea, David Flood

“…The primary outcomes were feasibility and acceptability, measured through 20 structured interviews with Ministry of Health employees and by examining enrolment and retention data. …”
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PATHOLOGICAL CHANGES IN MICE TREATED WITH CYCLOPHOSPHAMIDE AND EXOGENOUS DNA by E. V. Dolgova, V. P. Nikolin, N. A. Popova, A. S. Proskurina, K. E. Orishchenko, E. A. Alyamkina, Ya. R. Efremov, S. I. Baiborodin, E. R. Chernykh, A. A. Ostanin, S. S. Bogachev, T. S. Gvozdeva, E. M. Malkova, O. S. Taranov, V. A. Rogachev, A. S. Panov, S. N. Zagrebelnyi, M. A. Shurdov

“…This suggestion is proven by structural equivalents of functional involution of lymphoid organs, such as thymus, spleen, and lymph nodes.We speculate that the death of treated animals resulted from multiple organ dysfunctions caused by accidental involution of lymphoid organs and the systemic inflammatory response syndrome, both associated with injections of fragmented exogenous DNA into experimental animals within the «death window», which corresponds to the final step in the repair of the majority of CP-induced double-strand breaks.…”
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Quantification of Forest Regeneration on Forest Inventory Sample Plots Using Point Clouds from Personal Laser Scanning by Sarah Witzmann, Christoph Gollob, Ralf Kraßnitzer, Tim Ritter, Andreas Tockner, Lukas Moik, Valentin Sarkleti, Tobias Ofner-Graff, Helmut Schume, Arne Nothdurft

“…Light detection and ranging (LiDAR) technology, particularly ground-based LiDAR, has emerged as a powerful tool for assessing typical forest inventory parameters, providing high-resolution, three-dimensional data on the forest structure. Therefore, it is logical to attempt a LiDAR-based quantification of forest regeneration, which could greatly enhance area-wide monitoring, further supporting sustainable forest management through data-driven decision making. …”
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Probing the Dual Role of Ca²⁺ in the <i>Allochromatium tepidum</i> LH1–RC Complex by Constructing and Analyzing Ca²⁺-Bound and Ca²⁺-Free LH1 Comple... by Mei-Juan Zou, Shuai Sun, Guang-Lei Wang, Yi-Hao Yan, Wei Ji, Zheng-Yu Wang-Otomo, Michael T. Madigan, Long-Jiang Yu

“…Here, we use the purple bacterium <i>Rhodospirillum rubrum</i> strain H2 as a host to express Ca²⁺-bound and Ca²⁺-free <i>Alc. tepidum</i> LH1-only complexes composed of α- and β-polypeptides that either contain or lack the calcium-binding motif WxxDxI; purified preparations of each complex were then used to test how Ca²⁺ affects their thermostability and spectral features. The cryo-EM structures of both complexes were closed circular rings consisting of 14 αβ-polypeptides. …”
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Dual role of ramR mutation in enhancing immune activation and elevating eravacycline resistance in Klebsiella pneumoniae by Wei Yu, Peiyao Jia, Xiaobing Chu, Shengjie Li, Xinmiao Jia, Ying Zhu, Xiaoyu Liu, Yingchun Xu, Qiwen Yang

“…Concurrently, these mutations modulate lipid A structure by increasing 2‐hydroxy fatty acid chain abundance. …”
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Surgical nonunion treatment of large-sized defects of femur and tibia based on the diamond concept by Sebastian Findeisen, Louis Mennerat, Thomas Ferbert, Lars Helbig, Tim N. Bewersdorf, Tobias Großner, Christian Schamberger, Gerhard Schmidmaier, Michael Tanner

“…The mean time period from nonunion surgery to consolidation was 16.42 months (SD 9.73) Conclusion: Patients with presentation of a large-sized nonunion require a structured and sufficiently long follow-up to secure the consolidation of the former nonunion. …”
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NCAPD3 promotes diffuse large B-cell lymphoma progression through modulating SIRT1 expression in an H3K9 monomethylation-dependent manner by Tiange Lu, Juan Yang, Yiqing Cai, Mengfei Ding, Zhuoya Yu, Xiaosheng Fang, Xiangxiang Zhou, Xin Wang

“…Introduction: Condensin, a family of structural maintenance of chromosome complexes, has been shown to regulate chromosome compaction and segregation during mitosis. …”
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Delivery of dendritic cells targeting 3M2e-HA2 nanoparticles with a CpG adjuvant via lysosomal escape of Salmonella enhances protection against H9N2 avian influenza virus by Futing Jia, Wenfeng Wang, Yawen Tian, Ainul Zahra, Yingkai He, Chongbo Ge, Tongyu Zhang, Mingyue Wang, Jingshuo Gong, Gerui Zhang, Guilian Yang, Wentao Yang, Chunwei Shi, Jianzhong Wang, Haibin Huang, Xin Cao, Yang Zeng, Nan Wang, Zhannan Wang, Chunfeng Wang, Yanlong Jiang

“…HA2, the neck of the HA protein, and M2e, the extracellular N-terminal structural domain of the M2 protein, are conserved and effective protective antigens.In this study, the HA2 sequences were fused with three M2e copies (H9N2, H1N1 and H5N1) to the norovirus VP1 protein via the SpyTag-SpyCatcher platform to form self-assembled nanoparticles and display antigenic proteins on its surface, yielding pYL262. …”
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Acceptance of multiple micronutrient supplementations (MMS) and iron and folic acid supplement utilisation among pregnant and lactating women in the rural part of Ethiopia, 2022: a... by Zewdie Birhanu, Menen Tsegaw, Stanley Chitekwe, Ramadhani Noor, Rachana Sharma, Finina Abebe, Yordanos Tadesse Kidanemariam, Ahmednasir Abdi, Hiwot Getachew, Asli Hassan Aden, Tesfaye Chuko, Tariku Dejene, Ahmed Mohammed Dawd

“…A multistage random sampling technique was employed. A structured questionnaire was used to collect data from 410 pregnant and lactating women. …”
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The Protocol for the Multi-Ethnic, multi-centre raNdomised controlled trial of a low-energy Diet for improving functional status in heart failure with Preserved ejection fraction (... by Noelle Robertson, Melanie J Davies, Thomas Yates, Gerry P McCann, Gaurav Singh Gulsin, Emer M Brady, Joanne V Wormleighton, Eylem Levelt, Oliver Rider, Jiliu Pan, Christopher Miller, Iain Squire, Mehak Asad, Fardad Soltani, Michelle Hadjiconstantinou, Rachel L Brown, Joanna M Bilak

“…Participants will undergo glycometabolic profiling, echocardiography, MRI for cardiovascular structure and function, body composition analysis (including visceral and subcutaneous adiposity quantification), Kansas City Cardiomyopathy Questionnaire (KCCQ) and Six-Minute Walk Test (6MWT), at baseline and 12 weeks. …”
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Phenome-wide association studies between SERINC2 and neuropsychiatric disorders by Ping Liu, Xinqun Luo, Liping Cao, Yong Zhang, Jiawu Ji, Xiaoping Wang, Kesheng Wang, Xinghua Pan, Ruilan Yang, Zewen Tan, Yunlong Tan, Chiang-shan Li, Xiaoyun Guo, Zhiren Wang, Xingguang Luo, Xingguang Luo

“…Finally, functional studies on the differential SERINC2 mRNA expression in brains and the potential regulatory effects of disease-risk alleles on SERINC2 mRNA expression, gray matter volumes (GMVs) of subcortical structures, cortical surface area (SA) and average thickness (TH) were conducted.ResultsIn European descent, alcoholism was most significantly associated with SERINC2 variants (245 SNPs with 5.5×10-8≤p ≤ 0.049 and 4.9×10-5≤q ≤ 0.034) that were largely shared across cocaine dependence, marijuana dependence, nicotine dependence, polysubstance dependence, schizophrenia, OCD, and autism (8.2×10-8≤p ≤ 0.050 and 1.9×10-5≤q ≤ 0.049); in Chinese population, bipolar disorder was also significantly associated with SERINC2 variants (10 SNPs: 1.3×10-4≤p ≤ 4.7×10-4 and 0.025≤q ≤ 0.031). …”
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sST2 as a New Biomarker of Chronic Kidney Disease-Induced Cardiac Remodeling: Impact on Risk Prediction by Maëlle Plawecki, Marion Morena, Nils Kuster, Leila Chenine, Hélène Leray-Moragues, Bernard Jover, Pierre Fesler, Manuela Lotierzo, Anne-Marie Dupuy, Kada Klouche, Jean-Paul Cristol

“…No patient had reduced ejection fraction. 112 patients had left ventricular hypertrophy, and 184 presented cardiac dysfunction, with structural, functional abnormalities or both. sST2 was independent of age and eGFR (ρ=0.05, p=0.44, and ρ=−0.07, p=0.3, respectively). …”
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