Computer-guided identification of novel inhibitors of apoptosis-signaling kinase 1 from Spondia mombim bioactive compounds against colorectal cancer by Olusola Olalekan Elekofehinti, Hannah Oluwaseun Popoola, Adedotun Olayemi Oluwatuyi, Opeyemi Iwaloye, Moses Orimoloye Akinjiyan, Oluwamodupe Cecilia, Frank Abimbola Ogundolie, Olalekan Isaac Olatunde, Oussama Abchir, Samir Chtita, Joao Batista Texeira Rocha

“…The constructed quantitative structure–activity relationship model with a trustworthy R 2 coefficient value supports the inhibition prowess of these compounds. …”
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A holistic review of nanomaterials in strain-hardening cementitious composites: Insights into micro- and macromechanical, deformation, smart, and durability properties by Isyaka Abdulkadir, Leong Sing Wong, Lee Woen Ean, G. Murali, Bashar S. Mohammed

“…These mechanisms include refining the pore structure, improving the interfacial transition zone (ITZ) between the fibers, cementitious matrix, and aggregates, and providing additional nucleation sites for cement hydration products. …”
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Parameter influences of FTO/ZnO/Cu₂O photodetectors fabricated by electrodeposition and spray pyrolysis techniques by Muthiah N. Najah, Frida A. Rahmania, Integralita Cahyanti, Maulida Hesnaty, Siti Hajar Alias, Djoko Hartanto, Wahyu Prasetyo Utomo, Retno Sari, Hadi Nur

“…The FTO layers were produced via spray pyrolysis, with optimal deposition achieved at 400 °C and efficiency value 0.0149 %, resulting in a dense, transparent structure. Meanwhile the efficiency of samples at temperatures of 350°C, 450°C, and 500°C are 0.0032 %, 0.0042 %, and 0.0037 %. …”
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The efficacy of neoadjuvant immunotherapy and lymphocyte subset predictors in locally advanced esophageal squamous cell carcinoma: A retrospective study by Ruotong Wang, Shaodi Wen, Xiaoyue Du, Jingwei Xia, Bowen Hu, Yihan Zhang, Guoren Zhou, Feng Jiang, Xiaomin Lu, Miaolin Zhu, Xinyu Xu, Bo Shen

“…We assessed peripheral blood indexes and tertiary lymphoid structures (TLS) density to evaluate their impact on pathological response and prognosis, leading to a clinical prediction model for treatment efficacy and survival. …”
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Parasitic infection prevalence in tuberculosis patients and their household contacts in the Littoral Region of Cameroon by Lucy Cho Nchang, Chefor Magha, Patience Agwa Fonong, Narcisse Victor Tchamatchoua Gandjui, Nancielle Mbiatong Tchatat, Desmond Akumtoh Nkimbeng, Frank Noel Nietcho, Juluis Visnel Foyet, Fanny Fri Fombad, Tatiana Djikeussi Katcho, Jerome Fru Cho, Achim Hoerauf, Manuel Ritter, Samuel Wanji

“…Socio-demographic data and associated factors were collected using structured questionnaires. Blood, stool, urine and skin snip samples were collected following standard guidelines for investigation of parasitic infections. …”
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Physiological and multi-omics analysis revealed the mechanism of arbuscular mycorrhizal fungi to cadmium toxicity in green onion by Kunhao Xie, Yixuan Chen, Xiaoqin Wang, Xiaoya Zhou, Yizhe Cheng, Xianchang Yu, Jun Wang, Mintao Sun, Yansu Li, Chaoxing He

“…AMF formed an effective symbiotic relationship with green onion roots under Cd stress, increased plant biomass, improved root structure and enhanced root vitality. AMF-colonized green onion had reduced Cd content in roots and leaves by 63.00 % and 46.50 %, respectively, with Cd content being higher in the roots than in the leaves. …”
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Zinc lysine and selenium yeast can effectively improve the reproductive performance of Northeast white geese by Jingchun Li, Heze Feng, Yulun Song, Hechuan Wang, Yingying Dong, Han Li, Qing Guo, Shengjun Liu, Yanbing Li

“…The aim of this study was to investigate the effects of dietary supplementation with selenium yeast (YS) and zinc lysine (ZL) on goose semen quality, testicular tissue structure, reproductive hormone levels, antioxidant capacity and egg fertilization rate. …”
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Establishment of <i>Echinococcus granulosus EgM123</i> Recombinant Gene Rabies Virus SRV₉ and Identification of Its Biological Characteristics by Yueqi Yang, Mengdan Hou, Guicheng Su, Xiaoyan Ma, Xiaohui Su, Kunlei Li, Songhan Liu, Luheng Xiao, Jingjing Yao, Jiahao Zhai, Xiaoying Wei, Yang Zhou, Qianqian Lai, Yuwei Dong, Jieyu Liu, Shaohua Zhai

“…The rescued virus-infected BSR cells were characterized by TEM, and the results indicated that bullet-like viral particles with an average size of 148.47 nm and a cyst structure were present in the cytoplasm of BSR cells; the expression levels of continuously cultivated 9th-, 10th-, 11th-, 12th-, and 13th-generation viruses were quantified by qRT-PCR, and the results showed that mRNA expression of the virus was upregulated. …”
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Effects of nano-selenium and/or vitamin E supplementation on growth performance, antioxidant status, histopathology and resistance to Aspergillus flavus in Nile tilapia (Oreochromi... by Walaa K. Bazina, Wesam A. Tawfik, Nadia A. Abd Elghany, Saadea Saadony, Zulhisyam Abdul Kari, Muna Omer Alamoudi, Mohamed Y. M. Aly, Abuelhassan Elshazly Younis, Roshmon Thomas Mathew, Moaheda E. H. Eissa, Mohammad Bodrul Munir, Saadiah Ibrahim, Ismail Yousef, Yusuf O. H. Omar, El-Sayed Hemdan Eissa, Heba E. Abd Elnabi

“…Histopathological analysis revealed somewhat lacerated gill arches in fish fed SeNPs, VE, or their combination, but the overall gill structure remained normal. The SeNPs + VE group exhibited improved villi length and normal morphology of portal veins and hepatic sinusoids, though some vacuolated hepatocytes were noted. …”
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The Role of P‐Wave Variables in Enhancing Prediction of New‐Onset Atrial Fibrillation in Patients With Acute Myocardial Infarction by Na Yang, Xiaoyan Li, Bo Wu, Longhao Dai, Shaobin Yang, Qinning Zhang, Shaobin Jia

“…Some P‐wave variables (P‐wave duration [PWD], P‐wave amplitude, and interatrial block [IAB]), reflecting the process of electrical and structural remodeling, could predict the risk of atrial fibrillation (AF). …”
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Impact of mother’s own milk expression practices and processing treatments on infant health and growth outcomes: a systematic review protocol by Daniel Klotz, Carolyn Smith, Agnieszka Bzikowska-Jura, Marzia Giribaldi, Tanya Cassidy, Laura Cavallarin, Serena Gandino, Karolina Karcz, Chiara Peila, Bartłomiej Walczak, Aleksandra Wesolowska

“…We will apply a hybrid search strategy, by combining structured database search with predefined snowballing searches. …”
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Enhanced photocatalytic degradation of Rhodamine B using polyaniline-coated XTiO3(X = Co, Ni) nanocomposites by Mariyem Abouri, Abdellah Benzaouak, Mohamed Elouardi, Lahcen El Hamdaoui, Fatima Zaaboul, Khalil Azzaoui, Belkheir Hammouti, Rachid Sabbahi, Shehdeh Jodeh, Mohammed Alaoui El Belghiti, Adnane El Hamidi

“…X-ray diffraction (XRD) confirmed that the crystalline structures of CoTiO3 and NiTiO3 remained intact post-polymerization. …”
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In vitro modeling of feline gut fermentation: a comprehensive analysis of fecal microbiota and metabolic activity by Qianle Ren, Qianle Ren, Yuling Li, Mingmei Duan, Jinjun Li, Fangshu Shi, Yun Zhou, Wanjing Hu, Junfu Mao, Xiaoqiong Li

“…The results revealed that the substrate composition in the medium differentially impacts bacterial community structure and fermentation characteristics. High levels of carbon and nitrogen sources can substantially increase gas production, particularly CO2, while also significantly enhancing the production of short-chain fatty acids (SCFAs). …”
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Genome-wide identification and expression analysis of phytochrome gene family in Aikang58 wheat (Triticum aestivum L.) by Zhu Yang, Zhu Yang, Wenjie Kan, Wenjie Kan, Ziqi Wang, Caiguo Tang, Yuan Cheng, Yuan Cheng, Dacheng Wang, Dacheng Wang, Yameng Gao, Lifang Wu, Lifang Wu

“…In this study, we employed bioinformatics methods to identify eight TaAkPHY genes in the Aikang58 wheat variety. Based on gene structure, conserved domains, and phylogenetic relationships, the TaAkPHY gene family exhibits a high degree of conservation. …”
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Research on the Seismic Response Law of Complete Morphology of Butted Well Salt Cavern for Large-Scale Underground Energy Storage by Haitao Li, Dewen Zheng, Kang Li, Qiqi Wanyan, Lina Ran, Yanxia Kou, Song Bai, Jianan Wu, Jianchao Jia, Yunfei Wen, Yuanqing Wang, Hongyan Xing, Kuoyuan Zhu, Jingen Deng

“…The three-dimensional seismic techniques excel in identifying complex geological structures but have a limited understanding of underground old salt cavity morphology, thus the seismic forward simulation method is utilized to study their seismic response patterns. …”
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Utilisation of ChatGPT and other Artificial Intelligence tools among medical faculty in Uganda: a cross-sectional study [version 2; peer review: 1 approved, 2 approved with reserva... by Job Kuteesa, Faith Oguttu, Ian Guyton Munabi, Aloysius Gonzaga Mubuuke, Sarah Kiguli, Ritah Nantale, David Mukunya, Elizabeth Ajalo, Frank Kayemba, Jonathan Babuya, Kennedy Pangholi, Amelia Margaret Namiiro, Suzan Langoya Akuu, Steven Ekak, Ronald Tweheyo, Kirsten Nantongo, Brenda Nakitto, Milton W. Musaba, Joseph Luwaga Mpagi

“…Participants were recruited consecutively. We used a semi-structured questionnaire to collect data on participants’ socio-demographics and the use of AI tools such as ChatGPT. …”
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Real-Life State of Anti-Hepatitis B Virus Drug Choice in Child-Bearing Age Male Patients and Effect on Fertility and Fetal Safety by Zhao X. Hu, Yi N. Ye, Wei G. Wu, Xu J. Liang, Qi W. Wu, Ao Zhang, Xing R. Zheng, Zhi L. Gao, Liang Peng, Chan Xie

“…Chronic hepatitis B (CHB) patients in Guangdong province were surveyed using a structured questionnaire. We collected data including medication type, fertility, and birth defects. …”
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Evaluation of Two Different Solvents for Azolla pinnata Extracts on Chemical Compositions and Larvicidal Activity against Aedes albopictus (Diptera: Culicidae) by Rajiv Ravi, Nor Shaida Husna Zulkrnin, Nurul Nadiah Rozhan, Nik Raihan Nik Yusoff, Mohd Sukhairi Mat Rasat, Muhammad Iqbal Ahmad, Zulhazman Hamzah, Intan H. Ishak, Mohamad Faiz Mohd Amin

“…Meanwhile, the chemical composition of extracts and their structures have been identified using GCMS-QP2010 Ultra (Shimadzu) fitted with Rtx-5MS capillary column (30 m × 0.25 mm inner diameter, ×0.25 μm film thickness; maximum temperature, 370°C), coupled to QP2010 Ultra (Shimadzu) MS. …”
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Genetically Engineered Bacterial Ghosts as Vaccine Candidates Against <i>Klebsiella pneumoniae</i> Infection by Svetlana V. Dentovskaya, Anastasia S. Vagaiskaya, Alexandra S. Trunyakova, Alena S. Kartseva, Tatiana A. Ivashchenko, Vladimir N. Gerasimov, Mikhail E. Platonov, Victoria V. Firstova, Andrey P. Anisimov

“…The resulting frameless cell envelops are more reminiscent of bacterial sacs or bacterial skins than BGs. Although such structures are less naive than classical bacterial ghosts, they provide effective protection against infection by a hypervirulent strain of <i>K. pneumoniae</i> and can be recommended as candidate vaccines. …”
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Topologically constrained DNA-mediated one-pot CRISPR assay for rapid detection of viral RNA with single nucleotide resolutionResearch in context by Yanan Li, Ru Xu, Fenglei Quan, Yonghua Wu, Yige Wu, Yongyuan Zhang, Yan Liang, Zhenzhong Zhang, Hua Gao, Ruijie Deng, Kaixiang Zhang, Jinghong Li

“…The capacity of CRISPR/Cas13a for discriminating single nucleotide variant (SNV) in viral genome is leveraged by designing synthetic mismatches and hairpin structure in CRISPR RNA (crRNA), enabling robust discrimination of different SARS-CoV-2 variants. …”
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