Dietary Choline Deprivation Exacerbates Kidney Injury in Streptozotocin-Induced Diabetes in Adult Rats by Ahmed W. Al-Humadi, Carel W. le Roux, Neil G. Docherty, Werd Al-Najim, Martin Tze Wah Kueh, Andreas C. Lazaris, Charis Liapi

“…<b>Conclusions</b>: Ch deprivation affected kidney function and structure in STZ-induced diabetic rats. Choline deficiency and diabetes seem to have a synergistic effect, as evidenced by kidney biochemistry, histopathology, and immunohistochemistry. …”
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Genome-wide characterization and expression analysis of the ADF gene family in response to salt and drought stress in alfalfa (Medicago sativa) by Mengmeng Shi, Yike Wang, Peng Lv, Yujie Gong, Qi Sha, Xinyan Zhao, Wen Zhou, Lingtao Meng, Zegang Han, Lingxiao Zhang, Lingxiao Zhang, Yongwang Sun, Yongwang Sun

“…A phylogenetic analysis indicated that the MsADF genes could be classified into four distinct groups, with members within the same group exhibiting comparable gene structures and conserved motifs. The analysis of the Ka/Ks ratios indicated that the MsADF genes underwent purity-based selection during its evolutionary expansion. …”
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Cardiac Abnormalities in Acromegaly Patients: A Cardiac Magnetic Resonance Study by Xiaopeng Guo, Jian Cao, Peijun Liu, Yihan Cao, Xiao Li, Lu Gao, Zihao Wang, Ligang Fang, Zhengyu Jin, Yining Wang, Bing Xing

“…Age, body mass index (BMI), disease duration, and hypertension were associated with cardiac abnormalities (all p<0.05). In conclusion, structural and functional cardiac abnormalities can be comprehensively evaluated by CMR in acromegaly patients. …”
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NeuTox 2.0: A hybrid deep learning architecture for screening potential neurotoxicity of chemicals based on multimodal feature fusion by Xudi Pang, Xuejun He, Ying Yang, Ling Wang, Yuzhen Sun, Huiming Cao, Yong Liang

“…The ablation experiments indicated that NeuTox 2.0 can learn the deeper structural differences of molecules from various feature extractions and capture complex interactions and mapping relationships between various modalities, thereby improving performance for neurotoxicity prediction. …”
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Anti-NMDAR-Positive Small-Cell Lung Cancer Paraneoplastic Limbic Encephalitis: A Case Report and Literature Review by Raman Sohal, Steven H. Adams, Vishal Phogat, Abha Harish, Carlos Ynigo D. Lopez, Michael P. A. Williams, Kamal K. Khurana, Basel Abuzuaiter, Nia Jagroop, Bhavya Narapureddy

“…Given that PLE can precede the diagnosis of cancer, it is very important that once infectious, metabolic, nutritional, or structural disorders associated with short-term memory loss are ruled out that vigorous effort must be made to rule out underlying malignancy. …”
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Experimental analysis of micro-cavity influence on the effective solar absorptance of white sand curtain on porous obstructions of particle heating receivers by Rageh Saeed, Shaker Alaqel, Eldwin Djajadiwinata, Nader S. Saleh, Abdulelah Alswaiyd, Hany Al-Ansary, Syed Noman Danish, Abdelrahman El-Leathy, Zeyad Al-Suhaibani, Sheldon Jeter, Redhwan Almuzaiqer, Zeyad Almutairi

“…Particle curtain ESA was scrutinized across various parameters, particle flow rate, and PHR structural geometry, represented by porous obstruction packing, perforation size, and arrangements. …”
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Is The SARS-CoV2 Evolved in Human Being: A prospective Genetic Analysis by Salvatore Dimonte, Paywast Jamal Jalal, Hiwa Abdulrahman Ahmad, Safa Bakr Karim, Taib Ahmed Hama Soor, Salar Ibrahim Ali, Muhammed Babakir-Mina, Francesco Greco

“…The phylogenetic trees for all human coronaviruses with the novel Coronavirus have been built using a several complete amino acid sequences of the four known structural proteins, S (spike), E (envelope), M (membrane), and N (nucleocapsid). …”
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Improvement of crop production in controlled environment agriculture through breeding by Krishna Bhattarai, Andrew B. Ogden, Sudeep Pandey, Germán V. Sandoya, Ainong Shi, Amol N. Nankar, Murukarthick Jayakodi, Heqiang Huo, Tao Jiang, Pasquale Tripodi, Chris Dardick

“…In addition, CEA offers resilience to climate instability by growing inside protective structures. Products harvested from CEA systems tend to be of high quality, both internal and external, and are sought after by consumers. …”
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dyphAI dynamic pharmacophore modeling with AI: a tool for efficient screening of new acetylcholinesterase inhibitors by Yasser Hayek-Orduz, Dorian Armando Acevedo-Castro, Dorian Armando Acevedo-Castro, Juan Sebastián Saldarriaga Escobar, Brandon Eli Ortiz-Domínguez, María Francisca Villegas-Torres, Paola A. Caicedo, Álvaro Barrera-Ocampo, Natalie Cortes, Edison H. Osorio, Andrés Fernando González Barrios

“…Experimental results revealed that molecules, 4 (P-1894047), with its complex multi-ring structure and numerous hydrogen bond acceptors, and 7 (P-2652815), characterized by a flexible, polar framework with ten hydrogen bond donors and acceptors, exhibited IC₅₀ values lower than or equal to that of the control (galantamine), indicating potent inhibitory activity. …”
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The effect of Ocimum basilicum on the prevention of postpartum depression symptoms and sleep quality: A triple-blind randomized controlled clinical trial by Monireh Abdi, Elham Rezaei, Mojgan Mirghafourvand, Fatemeh Ebrahimi, Laleh Payahoo, Alireza Shafiei-Kandjani, Solmaz Ghanbari-Homaie

“…The EPDS and postpartum sleep quality scale were completed through structured interviews at eight weeks postpartum. The Mann-Whitney U test was used to compare the mean postpartum depression scores before and after the intervention, and ANCOVA was used to compare the mean postpartum sleep quality scores. …”
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Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that question by Brandon A. Kohrt, Dristy Gurung, Ritika Singh, Sauharda Rai, Mani Neupane, Elizabeth L. Turner, Alyssa Platt, Shifeng Sun, Kamal Gautam, Nagendra P. Luitel, Mark J.D. Jordans

“…We recommend evaluating multiple conditions, statistically adjusting prevalence estimates generated from self-report tools, and consistently using structured clinical interviews as a gold standard. We propose clinically meaningful detection as ‘good-enough’ diagnoses incorporating multiple conditions accounting for context, health system and types of interventions available. …”
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Challenges and barriers to physician decision-making for prescribing and deprescribing among patients with multimorbidity in eastern China’s primary care settings: a qualitative st... by Ming Yan, Zhijie Xu, Andrew Farmer, Yu Xia, Mi Yao, Lingyan Wu, Xinmei Zhou, Liyan Han

“…We aimed to investigate the experiences and perceptions of primary care physicians (PCPs) regarding their decision-making processes in prescribing and deprescribing medications for patients with multimorbidity, and identify the challenges and barriers they face.Design From 5 October 2023 to 27 January 2024, this qualitative study was conducted through semi-structured interviews that encouraged in-depth exploration of the participants’ experiences and perspectives. …”
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Transfer from long-term care to acute care and risk of new permanent cognitive or physical disability among long-term care residents in Canada: protocol for a retrospective cohort... by Sharon Kaasalainen, Daniel I McIsaac, Steven Hawken, Daniel Kobewka, Peter Tanuseputro, Amy Hsu, Robert Talarico, Colleen Webber, Ramtin Hakimjavadi, Celeste Fung, Mary M Scott, Doug Manuel, Christina Y Yin, Jackie Kierulf, Frank Molnar, Sandy Shamon, Aliza Moledina

“…We will fit marginal structural models (MSMs) to account for the known shortcomings of traditional regression modelling, such as collider bias. …”
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Silicon-based all-solid-state batteries operating free from external pressure by Zhiyong Zhang, Xiuli Zhang, Yan Liu, Chaofei Lan, Xiang Han, Shanpeng Pei, Linshan Luo, Pengfei Su, Ziqi Zhang, Jingjing Liu, Zhengliang Gong, Cheng Li, Guangyang Lin, Cheng Li, Wei Huang, Ming-Sheng Wang, Songyan Chen

“…Such an efficient ionic/electronic transport system also facilitates the uniform release of cycling expansion stresses from the Si particles and stabilizes bulk-phase and interfacial structure of anode. Consequently, the Li21Si5/Si–Li21Si5 anode exhibited a critical current density of 10 mA cm−2 at 45 °C with a capacity of 10 mAh cm−2. …”
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“Sleepless nights are a daily reality for us” how women experiencing homelessness in Addis Ababa, Ethiopia describe street life: a photovoice study by Kalkidan Yohannes, Kalkidan Yohannes, Kalkidan Yohannes, Mats Målqvist, Hannah Bradby, Yemane Berhane, Dagmawit Tewahido, Dagmawit Tewahido, Sibylle Herzig van Wees, Sibylle Herzig van Wees

“…In this study, we aimed to describe women’s experiences of street homelessness in their own terms and their suggestions to address their unmet needs.MethodsThis photovoice study draws on photos, focus group discussions, and semi-structured interviews. We conducted the study in collaboration with women in their reproductive years experiencing homelessness (n = 9). …”
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Isoxazole-based molecules restore NK cell immune surveillance in hepatocarcinogenesis by targeting TM4SF5 and SLAMF7 linkage by Ji Eon Kim, Hyun Su Kim, Wonsik Kim, Eun Hae Lee, Soyeon Kim, Taewoo Kim, Eun-Ae Shin, Kyung-hee Pyo, Haesong Lee, Seo Hee Jin, Jae-Ho Lee, Soo-Min Byeon, Dong Joo Kim, Jinwook Jeong, Jeongwon Lee, Minjae Ohn, Hyojung Lee, Su Jong Yu, Dongyun Shin, Semi Kim, Jun Yeob Yoo, Seung-Chul Lee, Young-Ger Suh, Jung Weon Lee

“…We used comprehensive structure activity relationship analysis to identify TM4SF5-specific isoxazole (TSI)-based small molecules that inhibit TM4SF5-mediated effects. …”
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A preliminary investigation into self-compassion and compassion-based intervention for mental health in the performing arts by Courtney C. Walton, James N. Kirby, Sabrina McKenzie, Sabrina McKenzie, Caroline X. Gao, Caroline X. Gao, Rosemary Purcell, Rosemary Purcell, Simon M. Rice, Simon M. Rice, Margaret S. Osborne, Margaret S. Osborne

“…Descriptive pre-post data combined with thematic analysis of semi-structured interview transcripts identified performer perspectives of the compassion-based intervention.ResultsIn Study 1, 211 participants were included in the final cross-sectional analysis, which showed that the intention to be self-compassionate was associated with lower symptoms of depression and anxiety, and higher wellbeing, even while controlling for several key demographic and risk factors (stress, alcohol use, and body appreciation). …”
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Surface prereacted glass-ionomer particles incorporated into resin composites promote biocompatibility for restoration of subgingival dental defects by Yueyi Yang, Jing Huang, Xuchen Hu, Meiling Jing, Yujie Zhang, Chenci Xu, Wenduo Tan, Xiaoyu Liu, Chenguang Niu, Zhengwei Huang

“…Surface prereacted glass ionomer (S-PRG) is a novel glass particle characterized by a three-layered structure and the release of multiple ions with bioactive potential. …”
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The externalization of internal experiences in psychotherapy through generative artificial intelligence: a theoretical, clinical, and ethical analysis by Yuval Haber, Dorit Hadar Shoval, Inbar Levkovich, Dror Yinon, Karny Gigi, Oori Pen, Tal Angert, Zohar Elyoseph, Zohar Elyoseph

“…To address these challenges, we propose the SAFE-AI protocol, offering clinicians structured guidelines for responsible AI integration in therapy. …”
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En plaque meningioma of the temporal bone: A systematic review on the imaging and management of a rare tumor by Arianna Burato, Giuseppe Maruccio, Livio Presutti, Ignacio Javier Fernandez, Gabriele Molteni, Giulia Molinari

“…Magnetic Resonance Imaging (MRI) revealed dural enhancement (28 %), temporal hyperostosis (20 %), a clearly enhancing extra-axial mass (28 %), compression of the surrounding vasculo-nervous structures (8 %) and the possible involvement of the temporal lobe (8 %). …”
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