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29401
Tunnel Back Analysis Based on Differential Evolution Using Stress and Displacement
Published 2020-01-01“…Because displacement due to the excavation process is significant, back analysis of the structure and ground can be performed easily. Recently, the length of a segment-lined tunnel driven by the mechanized tunneling method is increasing. …”
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29402
Is subsurface geophysics as seismic and acoustic investigations a rescue to groundwater flow inversion?
Published 2022-10-01“…This poses the question of guiding conventional inversions on the basis of a prior guess as the subsurface structure obtained via geophysical investigations.…”
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29403
Improving the provision of clinical pharmacy services in low- and middle-income countries: a qualitative study in tertiary health facilities in Tanzania
Published 2025-01-01“…The reported challenges in providing CPS include healthcare structures, public policies, resources, workforce, culture and education inequalities. …”
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29404
Long-term effects of post-earthquake landslides on vegetation ecosystem net carbon
Published 2025-02-01“…Subsequently, the Random Forest Regression Model and Structural Equation Model were used to explore the environmental drivers of ENCL. …”
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29405
COVID-19 health information needs of older adults from ethnic minority groups in the UK: a qualitative study
Published 2022-06-01“…The study highlights that health information interventions should recognise the intersection between multigenerational living, family structure, and the health and well-being of older adults, and should promote intergenerational discussion.…”
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29406
Calibrating the Color–Magnitude Relation of M Giants by Using Open Clusters
Published 2025-01-01“…M giants, with their distinctive properties such as high luminosity, serve as excellent indicators for mapping the structure of the Milky Way. The distance to distant M giants can be determined by using the color–magnitude relation (CMR), which is derived from color–magnitude diagrams of specific systems in previous studies. …”
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29407
Impact of gas flaring on acute respiratory distress among pregnant women and newborn babies in Delta State Central Senatorial District, Nigeria
Published 2024-12-01“…Using a multi-stage random sampling technique, a structured survey questionnaire was used to collect respondents’ RDS experiences and that of their new borne. …”
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29408
SARS-CoV-2 ORF3a accessory protein is a water-permeable channel that induces lysosome swelling
Published 2025-02-01“…To unravel the potential function of ORF3a, here we employed a multidisciplinary approach including patch-clamp electrophysiology, videoimaging, molecular dynamics (MD) simulations, and electron microscopy. Preliminary structural analyses and patch-clamp recordings in HEK293 cells rule out ORF3a functioning as either viroporin or proton (H+) channel. …”
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29409
Lack of intracranial atherosclerosis in various atherosclerotic mouse models
Published 2025-01-01“…We suggest that differences in brain vessel structure and induced antioxidant levels in the brain endothelium found in mouse and human tissue may contribute to the decreased atherosclerosis susceptibility of intracranial arteries.…”
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29410
In silico evaluation of missense SNPs in cancer-associated Cystatin A protein and their potential to disrupt Cathepsin B interaction
Published 2025-02-01“…These findings suggest that the E94K mutation could affect the protein structure and cathepsin B interaction, potentially leading to pathological consequences as evidenced by colorectal adenocarcinoma patients in the COSMIC (Catalogue of Somatic Mutations in Cancer) database.…”
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29411
Hexane extract from Lindera communis roots: wound healing properties and membrane-disruptive activities against methicillin-resistant Staphylococcus aureus
Published 2025-02-01“…The results are that LCH affected the growth of methicillin-resistant Staphylococcus aureus (MIC: 0.1 mg/mL) through morphological alterations and disrupting cell surface structures, causing membrane hyperpolarization and altering membrane integrity. …”
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29412
Tough choices: the experience of family members of critically ill patients participating in ECMO treatment decision-making: a descriptive qualitative study
Published 2025-02-01“…Data were collected using a semi-structured interview method and analysed using traditional content analysis approaches. …”
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29413
How does community health feature in Global Financing Facility planning documents to support reproductive, maternal, newborn, child and adolescent health and nutrition (RMNAH-N)? i...
Published 2024-12-01“…While some countries invest significantly in training CHWs, structural reforms and broader community engagement are lacking. …”
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29414
Scanning Electron Microscopic Assessment of Stent Coating Integrity in Jailed Wire Technique for Bifurcation Treatment
Published 2021-01-01“…Scanning electron microscopy (SEM) was used to evaluate stent coating integrity and wire structure. The degrees of coating defects were recorded as no, slight, moderate, and severe defects. …”
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29415
Distal protein-protein interactions contribute to nirmatrelvir resistance
Published 2025-02-01“…Particularly, L50F and other non-active site mutations can enhance the Mpro dimer-dimer interactions and help place the nsp5-6 substrate at the enzyme catalytic center. The structural and enzymatic activity data of Mpro L50F, L50F/E166A/L167F, and others underscore the importance of considering the whole substrate protein in studying Mpro and substrate interactions, and offers important insights into Mpro function, resistance development, and inhibitor design.…”
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29416
Assisted Parkinsonism Diagnosis Using Multimodal MRI—The Role of Clinical Insights
Published 2025-01-01“…The most discriminatory variables were responsiveness to levodopa, vertical gaze palsy, and the volumes of subcortical structures, including the red nucleus. Conclusion Machine‐learning‐assisted classification of MR‐imaging biomarkers gathered in routine care can assist in the diagnosis of parkinsonian syndromes as part of the diagnostic workup. …”
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29417
Design, Synthesis, and Antioxidant and Anti-Tyrosinase Activities of (<i>Z</i>)-5-Benzylidene-2-(naphthalen-1-ylamino)thiazol-4(5<i>H</i>)-one Analogs: In Vitro and In Vivo Insight...
Published 2025-01-01“…Fifteen compounds (<b>1</b>–<b>15</b>) constructed on a hybrid structure combining a β-phenyl-α,β-unsaturated carbonyl template and a 2-aminothiazol-4(5<i>H</i>)-one scaffold were designed and synthesized as potential novel anti-tyrosinase substances. …”
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29418
Culinary Arts: A Motivator Towards Community-Based Festival Attendance and Sustainability
Published 2024-12-01“…Convenience sampling method was further used to select 100 festivals attendees, making a total of 150 respondents and a structured close-ended questionnaire was administered for data gathering. …”
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29419
Electrochemically-driven solid oxide tubular membrane reactor for efficient separation of oxygen and argon
Published 2025-06-01“…The tubular membrane reactor featured an anode/electrolyte/cathode sandwich structure, offering a compact design particularly suited for gas separation. …”
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29420
Variabilities in Retinal Hemodynamics Across the Menstrual Cycle in Healthy Women Identified Using Optical Coherence Tomography Angiography
Published 2024-12-01“…The present study attempts to evaluate retinal and choroidal vascular and structural changes in healthy female subjects over the course of a menstrual cycle using OCT-A. …”
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