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25541
A single residue switch mediates the broad neutralization of Rotaviruses
Published 2025-01-01“…A combination of time-resolved cryo-electron microscopy (cryo-EM) and in situ cryo-electron tomography (cryo-ET) analysis reveals a counterintuitive dynamic process of virus inactivation, in which 7H13 asymmetrically binds to a conserved epitope in the capsid-proximal aspect of VP4, triggers a conformational switch in a critical residue—F418—thereby disrupts the meta-stable conformation of VP4 essential for normal viral infection. Structure-guided mutagenesis corroborates the essential role of the 7H13 heavy chain I54 in activating F418 switch and destabilizing VP4. …”
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25542
Self-Assembling Multifunctional Peptide Dimers for Gene Delivery Systems
Published 2015-01-01“…MPD polyplexes showed low transfection efficiency in HEK293 cells expressing low level of MMP-2 but high transfection efficiency in A549 and C2C12 cells expressing high level of MMP-2, meaning the enhanced transfection efficiency probably due to MMP-induced structural change of polyplexes. Bafilomycin A1-treated transfection results suggest that the transfection of MPD is mediated via endosomal escape by endosome buffering ability. …”
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25543
Highly Tunable Moiré Superlattice Potentials in Twisted Hexagonal Boron Nitrides
Published 2025-01-01“…It offers the possibility to reproduce uniform moiré structures with precise control piezo stage stacking and heat annealing. …”
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25544
A Proposed Bearing Load Identification Method to Uncertain Rotor Systems
Published 2021-01-01“…Using an interval analysis method, a calculated transient response of the rotor structure only subjecting to the bearing load can be approximated as a linear function of the interval parameters in the rotor system. …”
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25545
A High Efficiency Discontinuous Galerkin Method for 3D Ground-Penetrating Radar Simulation
Published 2025-01-01“…Numerous numerical simulation algorithms have been developed to improve the computational efficiency of GPR simulations, enabling the modeling of complex structures. The discontinuous Galerkin method is a high efficiency numerical simulation algorithm which can deal with complex geometry. …”
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25546
Biosynthesis of Multicomponent Nanoparticles with Extract of Mortiño (Vaccinium floribundum Kunth) Berry: Application on Heavy Metals Removal from Water and Immobilization in Soils...
Published 2018-01-01“…As-prepared nanoparticles were spherical measuring approximately 12 nm in diameter and contained iron oxides and iron sulfides in the crystal structure. Removal of copper and zinc from water using MCNPs showed high efficiencies (>99%) at pH above 6 and a ratio of 0.5 mL of the extract:10 mL 0.5 M FeCl3·6H2O : 10 mL 0.035 M Na2SO4. …”
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25547
Dust Explosion Characteristics of Agglomerated 35 nm and 100 nm Aluminum Particles
Published 2010-01-01“…From an analysis of the explosive residue, the study found that nanoparticles of 35 nm Al powder became filamentous strands after an explosion, where most of 100 nm Al nanoparticles maintained a spherical structure, This may be because the initial melting temperature of 35 nm Al is 435.71°C, while that for 100 nm Al is 523.58°C, higher by 87.87°C. …”
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25548
Differential between-therapist effects in more versus less standardized therapies for depression
Published 2024-12-01“…We also explored whether the size of therapist effects differed by degree of treatment standardization; in this trial, CBT was structured and manualized, whereas PDT was flexible and principle driven. …”
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25549
Exploring the nexus of migration dynamics and urban expansion: key drivers of horizontal spatial growth in Woldia Township, Ethiopia
Published 2025-01-01“…Data were collected through a structured questionnaire administered to a randomly selected sample of 395 respondents, complemented by key informant interviews and secondary data sources. …”
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25550
Pectin‐decorated selenium nanoparticles as a nanocarrier of curcumin to achieve enhanced physicochemical and biological properties
Published 2019-10-01“…Results showed that pectin‐SeNPs and Cur‐loaded pectin‐SeNPs (pectin‐SeNPs@Cur) exhibited monodisperse and homogeneous spherical structures in aqueous solutions with mean particle sizes of ∼61 and ∼119 nm, respectively. …”
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25551
Hepatocyte Growth Factor Effects on Mesenchymal Stem Cells Derived from Human Arteries: A Novel Strategy to Accelerate Vascular Ulcer Wound Healing
Published 2016-01-01“…HGF/SF did not increase hVW-MSC proliferation, whereas it enhanced the cell migration, the formation of capillary-like structures, and the expression of angiogenic markers (vWF, CD31, and KDR). …”
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25552
The Effect of a Card Game upon Achievements within Medical Terms Topic: MedTerm Game
Published 2022-08-01“…At the end of the implementation, the semi-structured interviews were also conducted with randomly selected students.. …”
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25553
Lactic acid in the vaginal milieu modulates the Candida-host interaction
Published 2025-12-01“…The cell wall of C. albicans cells grown in VSM+LA displayed a robust mannan fibrillar structure, β-glucan exposure, and low chitin content. …”
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25554
Disrupted Auto-Activation, Dysexecutive and Confabulating Syndrome Following Bilateral Thalamic and Right Putaminal Stroke
Published 2008-01-01“…Objective: Clinical, neuropsychological, structural and functional neuroimaging results are reported in a patient who developed a unique combination of symptoms after a bi-thalamic and right putaminal stroke. …”
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25555
Synthesis of MgFe2O4 Nanoparticles and its Application for Photodegradation of Methylene Blue
Published 2024-12-01“…Characterization results show that MgFe2O4 nanoparticles synthesized with the addition of 3 mL pumpkin seed extract have a crystal size of 3.87 nm, cubic spinel structure, average particle size of 29 nm, and band gap energy value of 1.94 eV. …”
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25556
Resonant analogue configurations in atomic condensates
Published 2025-01-01“…Finally, we study the physics of black-hole lasers as further examples of resonant analogue structures, distinguishing three stages in its time evolution. …”
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25557
Rapid Visual Screening for Seismic Assessment of Hospital Buildings: A Case Study of Kabul City
Published 2024-08-01“…The present research was conducted to evaluate the seismic vulnerability of the existing hospital buildings in Kabul City, with the aim of evaluating the current state of hospitals in terms of structural resistance. In the current applied research, the seismic vulnerability of 26 hospitals that had 79 existing buildings were assessed with the Rapid Visual Screening (RVS) technique of FEMA P-154 method in two levels for the first time, and their location was determined by Geographic Information System (GIS). …”
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25558
All‐Inorganic Perovskite Quantum‐Dot Optical Neuromorphic Synapses for Near‐Sensor Colored Image Recognition
Published 2025-02-01“…The dual functionality of each unit within the ONS device, which can be operated as either an optical sensor or a synaptic device depending on applied electrical polarity, provides significant advantages over previous heterogeneous integration methods, particularly regarding material selection, structural compatibility, and device fabrication complexity. …”
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25559
DESIGN AND STRESS ANALYSIS OF RX-122 ROCKET MOTOR TUBE USING NUMERICAL METHOD
Published 2024-12-01“…This approach provides a comprehensive and systematic method to achieve optimal structural performance under operational stress conditions, ensuring that only safe yet lightweight configurations are selected. …”
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25560
Stable Field Emissions from Zirconium Carbide Nanoneedle Electron Source
Published 2025-01-01“…In this study, a single zirconium carbide (ZrC) nanoneedle structure oriented in the <100> direction was fabricated by a dual-beam focused ion beam (FIB-SEM) system, and its field emission characteristics and emission current stability were evaluated. …”
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