MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology by Jin Wang, Jinyong Jiang, Haoliang Hu, Linxi Chen

“…Simultaneously, key structural domains of the MCU complex in Homo sapiens were identified. …”
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Deformation Failure and Support Test of Surrounding Rock in Deep Arched Roadway with Straight Wall by Shuqi Pan, Shuaitao Liu, Liming Cao, Jianqiang Guo, Chao Yuan

“…The results showed that after the deep roadway is excavated with preload and high stress, the surrounding rock deformation, failure, and instability of the roadway mainly experience 3 periods: the first period is the period of uniform deformation of the roadway surrounding rock, the second period is the development period of the roadway surrounding rock slab structure, and the third period is the period of instability of the roadway surrounding rock slab structure. …”
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In vitro effect of hCG on cryptorchid patients’ gubernacular cells: a predictive model for adjuvant personalized therapy by Andrea Errico, Giulia Ambrosini, Sara Vinco, Emanuela Bottani, Elisa Dalla Pozza, Nunzio Marroncelli, Jessica Brandi, Daniela Cecconi, Ilaria Decimo, Filippo Migliorini, Nicola Zampieri, Ilaria Dando

“…On these in vitro cultured cells, we analyzed the effect of hCG on cell proliferation, tubular structure formation, cellular respiration, reactive oxygen species content, and proteome. …”
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MicroRNA-21 as a biomarker in terminal stage oral squamous cell carcinoma (OSCC) in the South Indian population by Chevuru Sai Shreya Reddy, Ashikha Shirin Usman P.P, Dhanraj M. Ganapathy, Ameya K.P., Durairaj Sekar

“…Materials and methods: miR-21 secondary structure is predicted using Bioinformatics tools from OSCC. …”
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Design and Optimization of a Lightweight and Simple Self-Propelled Crawler Potato Combine Harvester by Caichao Liu, Ning Wu, Guangseng Cheng, Feng Wu, Fengwei Gu, Lili Shi, Bing Wang

“…It offers technical advantages such as a lightweight structure, auxiliary feeding and conveying, and manual assistance in sorting ton bags. …”
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How can urban expansion and ecological preservation be balanced? A simulation of the spatial dynamics of production-living-ecological spaces in the Huaihe River Eco-Economic Belt by Tonghui Yu, Shanshan Jia, Yu Zhang, Xufeng Cui

“…This study utilizes a combination of the Future Land Use Simulation (FLUS) model and the Markov model to analyze how various developmental scenarios might influence the spatial dynamics of the Production-Living-Ecological Spaces (PLES) structure. The findings reveal: (1) a distinct geographical differentiation of the PLES within the Huaihe River Eco-Economic Belt, with production and living spaces dispersed across urban areas and ecological space predominantly situated in the central and western regions; (2) an expansion of living space while production and ecological spaces are contracting, indicating significant urbanization, with the transition of living space primarily occurring through the conversion of agricultural land; (3) a relatively stable structural composition of the PLES projected by 2030, with production space still prevailing. …”
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Influence of Synthesis Conditions on the Capacitance Performance of Hydrothermally Prepared MnO₂ for Carbon Xerogel-Based Solid-State Supercapacitors by Vania Ilcheva, Victor Boev, Mariela Dimitrova, Borislava Mladenova, Daniela Karashanova, Elefteria Lefterova, Natalia Rey-Raap, Ana Arenillas, Antonia Stoyanova

“…In this study, the potential to modify the phase structure and morphology of manganese dioxide synthesized via the hydrothermal route was explored. …”
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Integrative genomic analyses combined with molecular dynamics simulations reveal the impact of deleterious mutations of Bcl-2 gene on the apoptotic machinery and implications in ca... by Ghazi Elamin, Ghazi Elamin, Zhichao Zhang, Depika Dwarka, Kabange Kasumbwe, John Mellem, Nompumelelo P. Mkhwanazi, Paradise Madlala, Paradise Madlala, Mahmoud E. S. Soliman

“…Multiple sequence, genetic, structural and disease phenotype analyses were applied in this study.ResultsAnalysis revealed that out of 130 mutations, approximately 8.5% of these mutations were classified as pathogenic. …”
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Nationwide incidence of central retinal artery occlusion in Japan: an exploratory descriptive study using the National Database of Health Insurance Claims (2011–2015) by Hiroshi Tamura, Akitaka Tsujikawa, Masahiro Miyake, Ai Kido, Hanako Ohashi Ikeda, Shusuke Hiragi

“…The crude incidence rates and age-standardised incidence rates of CRAO, according to the standard age-structure population of the WHO, were calculated.Results The crude incidence rate of CRAO in Japan was 5.84 (95% CI, 5.71 to 5.97) per 100 000 person-years. …”
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Pyrolysis conversion of crown-ether-based covalent networks to kagome metal-organic frameworks on Au(111) and Ag(111) by Yifan Liang, Jianing Wang, Ruoting Yin, Zhengya Wang, Xiaoqing Wang, Jie Meng, Shijing Tan, Chuanxu Ma, Qunxiang Li, Bing Wang

“…Additionally, we investigate the selective encapsulation of single guest picenes within the MOF structure, emphasizing the potential of triphenylene-based frameworks for advanced applications in sensing and molecular filtering. …”
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Cellular EMT-status governs contact guidance in an electrospun TACS-mimicking in vitro model by Lorenz Isert, Mehak Passi, Benedikt Freystetter, Maximilian Grab, Andreas Roidl, Christoph Müller, Aditi Mehta, Harini G. Sundararaghavan, Stefan Zahler, Olivia M. Merkel

“…By employing a rotating cylinder or static plate collector set-up, aligned fibers (TACS5-like structures) and randomly orientated fibers (TACS6-like structures) fibers were produced, respectively. …”
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Inhibition of cancer cells using target-specific 2A3 antibody-conjugated gold nanoclusters by Jui-Chi Kuo, Tsung-Rong Kuo, Fajar Rinawati, Erna Susilowati, Sucipto, Dyah Ika Krisnawati

“… Background: Metal nanoclusters (NCs) with outstanding structural and optical properties have been intensively validated for applications in nanomedicine and nanotechnology. …”
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SRADHO: statistical reduction approach with deep hyper optimization for disease classification using artificial intelligence by G. Sathish Kumar, E. Suganya, S. Sountharrajan, Balamurugan Balusamy, Adil O. Khadidos, Alaa O. Khadidos, Shitharth Selvarajan

“…Therefore, a complex structure perception is much essential by avoiding over-fitting and under-fitting. …”
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Unveiling the toxicity of JWH-018 and JWH-019: Insights from behavioral and molecular studies in vivo and vitro by Fenghua Zhou, Yan Shi, Sujun Tan, Xiaoli Wang, Weicheng Yuan, Shuqi Tao, Ping Xiang, Bin Cong, Chunling Ma, Di Wen

“…Due to the structural diversity and rapid prevalence of synthetic cannabinoids (SCs) in the market, the information linking the chemical structure of SCs to their toxicity remains scant, despite emerging in the 1970s. …”
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Three-dimensional reconstruction and connectivity analysis of REV-size organic matter in shales by Dongchen Liu, Dongchen Liu, Dongchen Liu, Xuefeng Yang, Xuefeng Yang, Shengxian Zhao, Shengxian Zhao, Deliang Zhang, Deliang Zhang, Shan Huang, Shan Huang, Ning Zhu, Ning Zhu, Jianqi Rong, Bowen Shi, Zhiwei Wang, Chao-Zhong Qin

“…To address this gap, in this work, we develop a novel workflow for numerical reconstruction of REV-size digital rocks of OM that integrates high-resolution information of pore structures in large-view MAPS (modular automated processing system) images. …”
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Investigating lightweight recycled brick aggregate concrete incorporating EPS beads: Application to masonry units by Samina Hameed, Syed Asad Ali Gillani, Muhammad Tahir, Rashid Hameed, Safeer Abbas, Moncef L. Nehdi, Muhammad Ahmad

“…This study focuses on developing lightweight recycled brick aggregate concrete (LRBAC) using recycled brick aggregate (RBA) and EPS beads, specifically designed for partition walls in seismic structures, where reduced weight enhances structural performance. …”
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Computational biology assisted exploration of phytochemicals derived natural inhibitors to block BZLF1 gene activation of Epstein–Bar virus in host by Muhammad Naveed, Muzamal Hussain, Tariq Aziz, Nimra Hanif, Nazia Kanwal, Arooj Arshad, Ayaz Ali Khan, Abdulrahman Alshammari, Metab Alharbi

“…Various bioinformatics methods were employed to predict and analyze the toxin protein structure obtained from NCBI, and its secondary and tertiary structures were predicted using PSIPRED and the AlphaFold. …”
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New insights into the N-glycomes of Dictyostelium species by Alba Hykollari, Daniel Malzl, Chunsheng Jin, Carina Eschenbach, Kristína Kianičková, Iain B.H. Wilson, Katharina Paschinger

“…The detailed glycomic analysis of their fruiting bodies was based on isomeric separation of the glycan structures by HPLC, followed by mass spectrometry in combination with enzymatic digests and chemical treatments. …”
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A Comparative Analysis of Laser-Ablated Surface Characteristics Between the Si Face and C Face of Silicon Carbide Substrates by Hsin-Yi Tsai, Yu-Hsuan Lin, Kuo-Cheng Huang, J. Andrew Yeh, Yi Yang, Chien-Fang Ding

“…Hardness testing indicates an initial hardness of 13,896 MPa for the C face, higher than that of the Si face, with both surfaces experiencing a drop to less than 1% of their original hardness (below 50 MPa) after ablation. Lattice structure analysis shows Moissanite-5H SiC and cubic silicon formation on the Si face, while the C face retains partial SiC structure. …”
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Functionality of bacterial communities in constructed wetlands used for water purification: influence of root components and seasonality by Yao Huang, Yao Huang, Weili An, Weili An, Tianzhu Ning, Zhiguang Ma, Yuelin Li, Ke Liu, Lingbo Ji, Lingbo Ji, Hongxiao Liu, Dafeng Hui, Hai Ren

“…., rhizosphere, rhizoplane, and endosphere) and their impact on water purification is still limited.MethodsTo address this knowledge gap, we employed high-resolution 16S rRNA deep amplicon sequencing to explore the bacterial community structure and assembly within the root components of three plant species (i.e. …”
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