Case report: Neuroendocrine carcinoma of the nasal cavity in a roe deer (Capreolus capreolus) by Gorazd Vengušt, Diana Žele Vengušt, Carlo Cantile, Mitja Gombač, Kristina Tekavec, Tanja Švara

“…Histopathologically, the tumor consisted of neoplastic cells forming sheets, nests, trabecular and cribriform structures separated by a delicate fibrovascular stroma. Mitoses were rare. Based on the histopathological and immunohistochemical findings, a neuroendocrine carcinoma was diagnosed. …”
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Up-to-Date Tailored Systemic Treatment in Pancreatic Ductal Adenocarcinoma by Caroline Y. K. Fong, Emma Burke, David Cunningham, Naureen Starling

“…Research has since focussed on understanding the role and interplay between various components of the desmoplastic stroma and tumour microenvironment, in addition to developing targeted therapies based on molecular features to improve the prognosis associated with this malignancy. …”
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Ameloblastic Fibro-Odontoma: A Diagnostic Challenge by Elen de Souza Tolentino, Bruna Stuchi Centurion, Marta Cunha Lima, Patrícia Freitas-Faria, Alberto Consolaro, Eduardo Sant'ana

“…Excisional biopsy was performed, and microscopic features showed strands and islands of odontogenic epithelium showing peripheral palisading and loosely arranged central cells, identical to stellate reticulum, embedded in a myxoid cell-rich stroma resembling the dental papilla. Dentin and enamel were also presented. …”
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A practical distribution pattern of α-SMA-positive carcinoma associated fibroblasts indicates poor prognosis of patients with pancreatic ductal adenocarcinoma by Bo Li, Meilong Shi, Yang Wang, Penghao Li, Xiaoyi Yin, Guoxiao Zhang, Xiaochao Kang, Huan Wang, Suizhi Gao, Kailian Zheng, Xiaohan Shi, Xiongfei Xu, Yukun Zhou, Hui Jiang, Wei Jing, Shiwei Guo, Gang Jin

“…Type II CAFs were designated as those located in the juxtatumoural stroma with α-SMA expression that was moderate or higher, and those in the peripheral stroma with α-SMA expression that was less than moderate. …”
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A Peripheral Ameloblastic Fibro-Odontoma in a 3-Year-Old Girl: Case Report, Immunohistochemical Analysis, and Literature Review by Yi-Chun Lin, Hsiu-Ming Hsu, Chiang-Shin Liu, Kuo Yuan

“…The histopathological examination of the excised lesion showed small islands and cords of odontogenic epithelium with cellular myxoid stroma in the subepithelial tissue. The mass contained calcified material and an enamel-like deposit. …”
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PIK3CA and p53 Mutations by Next Generation Sequencing in Lymphoepithelioma-Like Carcinoma of the Endometrium by Lucie Bienfait, Nicky D’Haene, Xavier Catteau, Jean-Christophe Noël

“…Lymphoepithelioma-like carcinoma of the endometrium is a very rare variant of endometrial carcinoma characterized by syncytial nests of pleomorphic epithelial cells and heavy infiltration of the stroma by lymphocytes (in particular CD8 cytotoxic T-lymphocytes) and plasma cells. …”
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Bio-orthogonal crosslinking and hyaluronan facilitate transparent healing after treatment of deep corneal injuries with in situ-forming hydrogels by Fang Chen, Uiyoung Han, Thitima Wungcharoen, Youngyoon Amy Seo, Peter Le, Li Jiang, Nae-Won Kang, Euisun Song, Kyeongwoo Jang, David Mundy, Gabriella Maria Fernandes-Cunha, Sarah Heilshorn, David Myung

“…Recently, in situ-forming corneal stroma substitutes have emerged, offering potential solutions to these limitations. …”
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Reporting a Rare Case of Pleomorphic Adenoma of the Breast by Tahere Khamechian, Javad Alizargar, Tahere Mazoochi

“…After an excisional biopsy, the pathologist found proliferation in epithelial and myoepithelial cells that had small and multiple nuclei, myxoid and chondroid stroma. Immunohistochemistry stain was positive for S-100 and patchy for GFAP in tumor cells and for SMA around the tubule-glandular and tumor cell aggregates and suggested PA of the breast. …”
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Sclerosing odontogenic carcinoma presenting in the maxilla of a 64-year-old female: A case report by Leyn B. Shakhtour, Jonathan Tucci, Barbara Murphy, Kim Ely, Michael C. Topf

“…A partial maxillectomy was remarkable for scattered small, angulated nests and long, thin cords of cuboidal cells infiltrating a markedly sclerotic stroma. Bony changes consistent with fibrous dysplasia were again seen. …”
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Effects of Fluorescein Staining on Laser In Vivo Confocal Microscopy Images of the Cornea by Christine W. Sindt, D. Brice Critser, Trudy K. Grout, Jami R. Kern

“…Responses were statistically similar to guessing for the epithelium (48% ± 14% of respondents correct per image) and the subbasal nerve plexus (49% ± 11% correct), but results were less clear for the stroma. Dendritic immune cells were quantified in bilateral images from subjects who had been unilaterally stained with fluorescein. …”
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Rare epithelial gastric cancers: a review of the current treatment knowledge by Angelica Petrillo, Margaret Ottaviano, Luca Pompella, Emilio Francesco Giunta, Pasquale Pisapia, Gianpaolo Marte, Andrea Tufo, Sara Di Lorenzo, Jessica Orefice, Chiara Miceli, Umberto Malapelle, Bruno Daniele, Ferdinando De Vita

“…Hence, we focused on the treatment of the following rare GCs: rare gastric adenocarcinomas (hepatoid adenocarcinoma, medullary carcinoma with lymphoid stroma, Paneth cell carcinoma and Salivary Gland carcinoma); squamous cell carcinoma; adenosquamous carcinoma; neuroendocrine gastric neoplasms; gastroblastoma.…”
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Dr Punctal Polyp, First Case Presentation by Nazia Qidwai

“…They were found to be polypoidal fragments of tissue covered by stratified squamous epithelium. The stroma was fibrous and showed mild chronic non-specific inflammation composed of lymphocytes and few plasma cells. …”
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Resolving the Two “Bony” Faces of PPAR-γ by Beata Lecka-Czernik, Larry J. Suva

“…Osteoblasts and adipocytes are derived from marrow mesenchymal stroma/stem cells (MSC). The milieu of intracellular and extracellular signals that controls MSC lineage allocation is diverse. …”
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Post-traumatic Corneal Ocular Surface Squamous Neoplasia: A Case Report by Keerti Wali, Nikita Sankolli, Savitri Nerune

“…AS-OCT confirmed the separation of corneal epithelial mass from underlying iris tissue by thinned scarred corneal stroma. An excisional biopsy with 2mm conjunctival margins and a limbal conjunctival autograft was performed. …”
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Spontaneous Reattachment of a Posteriorly Dislocated Endothelial Graft: A Case Report by Ka Wai Kam, Alvin L. Young

“…The patient was instructed to lie prone full time, and on postoperative day three, the graft was found to be reattached to the stroma with spontaneous resolution of corneal oedema, indicating restoration of pump function of endothelium graft. …”
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The colorectal cancer microenvironment: Preclinical progress in identifying targets for cancer therapy by Abdo Meyiah, Faez Iqbal Khan, Dia Aldeen Alfaki, Khaled Murshed, Afsheen Raza, Eyad Elkord

“…These models give insights into understanding the role of stroma and immune cell components of the TME in CRC and improve clinical responses, providing insights in novel treatment options. …”
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Epithelioid Hemangioendothelioma with WWTR1-CAMTA1 Fusion in the Parotid Gland Presenting as Bell’s Palsy by Landon J. Kunzelman, Shweta Agarwal, Nathan Boyd, Cory J. Broehm

“…Surgical resection showed a tumor comprised of atypical cells with occasional intracytoplasmic vacuoles in a fibromyxoid stroma. Immunohistochemical stains demonstrated the neoplastic cells expressed ERG, CD31, and CD34, confirming vascular differentiation. …”
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Fibrin and Collagen Differentially but Synergistically Regulate Sprout Angiogenesis of Human Dermal Microvascular Endothelial Cells in 3-Dimensional Matrix by Xiaodong Feng, Marcia G. Tonnesen, Shaker A. Mousa, Richard A. F. Clark

“…Alteration of ECM composition and architecture is a hallmark feature of wound clot and tumor stroma. We previously reported that during angiogenesis, endothelial cell responses to growth factors are modulated by the compositional and mechanical properties of a surrounding three-dimensional (3D) extracellular matrix (ECM) that is dominated by either cross-linked fibrin or type I collagen. …”
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Adipocyte Atrophy Mimicking Signet Ring Cell Carcinoma of the Gallbladder by Benjamin van Haeringen, Leo Francis, Emily Olive, Daniel James

“…Compared to malignant signet ring cell carcinoma, benign signet ring cell change is more likely to retain normal lobulated architecture without mass formation, lack significant atypia, have myxoid stroma with a prominent capillary network, and show positive staining S100 protein with negative staining for cytokeratins and mucin. …”
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Penile Livedoid Vasculopathy: First Reported Case by Ahmad Hallak, William Bennett, Mohammed Adib Tanbir, Supriya R. Donthamsetty, Bethaney Vincent

“…Due to diagnostic uncertainty, a biopsy was performed which revealed hyaline thrombi within the lumens of small vessels within the upper to mid dermis, fibrinoid material in the walls of these blood vessels and within the perivascular stroma with overlying and adjacent epidermal spongiosis, and mild perivascular lymphocytic infiltrate with a few scattered neutrophils most consistent with livedoid vasculitis. …”
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