Mutant glycosidases for labeling sialoglycans with high specificity and affinity by Shuyu Liang, Qi Tang, Xunzi Guo, Zi’an Li, Yilan Guo, Jinghan Chang, Bo Cheng, Qitao Song, Jiayu Sun, Peng Dai, Xing Chen

“…By mutating a key catalytic residue of Streptococcus pneumoniae neuraminidase A (SpNanA) and Ruminococcus gnavus neuraminidase H (RgNanH), we develop GRAB-Sia and GRAB-Sia3 recognizing total sialoglycans and α2,3-sialosides, respectively. …”
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Noninvasive Monitoring of Pneumococcal Meningitis and Evaluation of Treatment Efficacy in an Experimental Mouse Model by Jagath L. Kadurugamuwa, Kshitij Modi, Jun Yu, Kevin P. Francis, Carlos Orihuela, Elaine Tuomanen, Anthony F. Purchio, Pamela R. Contag

“…Noninvasive real-time in vivo bioluminescent imaging was used to assess the spread of Streptococcus pneumoniae throughout the spinal cord and brain during the acute stages of bacterial meningitis. …”
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Clinico-Microbiological Profile and Treatment Outcome of Infectious Scleritis: Experience from a Tertiary Eye Care Center of India by Srikant Kumar Sahu, Sujata Das, Savitri Sharma, Kalyani Sahu

“…Isolated organisms included Staphylococcus species (spp) (n=5), Fungus (n=4), Nocardia spp (n=3), two each of atypical Mycobacterium spp and Streptococcus pneumoniae and one Pseudomonas aeruginosa. Treatment included intensive topical antimicrobial in all eyes and systemic medication in 15 (88.2%) patients; surgical exploration was needed for 13 (76.5%) patients and scleral patch graft was done in four (23.5%) patients. …”
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Helmet Ventilation in a Child with COVID-19 and Acute Respiratory Distress Syndrome by Ke-Yun Chao, Chao-Yu Chen, Xiao-Ru Ji, Shu-Chi Mu, Yu-Hsuan Chien

“…The COVID-19 polymerase chain reaction test and urine antigen test for Streptococcus pneumoniae were both positive, and sputum culture yielded Pseudomonas aeruginosa. …”
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Nasopharyngeal Bacterial Carriage in the Conjugate Vaccine Era with a Focus on Pneumococci by V. T. Devine, J. M. Jefferies, S. C. Clarke, S. N. Faust

“…During this time, the carriage of vaccine-type Streptococcus pneumoniae decreased but pneumococcal carriage remained stable due to increases in non-vaccine-type S. pneumoniae. …”
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Bacterial Culture of Tear Duct Infections Secondary to Congenital Nasolacrimal Duct Obstructions by Weiming Yang, Li Shen, Anken Wang, Meiyan Li, Chenhao Yang

“…The most prevalent Gram-positive bacteria were Streptococcus viridans (67 isolates, 30%), followed by Staphylococcus aureus (36 isolates, 16.1%) and Streptococcus pneumoniae (5 isolates, 2.2%). The most prevalent Gram-negative bacteria were Neisseria (nonpathogenic) (25 isolates, 11.2%), followed by Escherichia coli (16 isolates, 7.2%) and Haemophilus influenzae (16 eyes, 7.2%). …”
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Synthesis and Microbiological Activity of Some Newly Synthesized Derivatives of 2-Oxo-2H-chromen-2-one by Majlinda Daci-Ajvazi, Sevdije Govori, Shuhreta Omeragiq

“…Based on the biological activity of chromene-2-ones and heterocyclic compounds condensed in position 3 and 4, we also studied microbiological activity of these new compounds (5-8), against Staphylococcus aureus ATCC 25923, Streptococcus pneumoniae, Aeromonas Salmonicida, Bacillus spp and some of them exhibited significant activity.…”
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Community-Acquired Pneumonia Requiring Hospitalization among French Guianese Children by Alexandre Cannesson, Narcisse Elenga

“…The main pathogens were respiratory syncytial virus (31.2%), Streptococcus pneumoniae (20.4%), Haemophilus influenzae (11.8%), and Mycoplasma pneumoniae (10.8%). …”
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Elegant and Innovative Recoding Strategies for Advancing Vaccine Development by François Meurens, Fanny Renois, Uladzimir Karniychuk

“…Beyond viral vaccines, recoding can apply to bacterial vaccines, as exemplified by modified <i>Escherichia coli</i> and <i>Streptococcus pneumoniae</i> strains, which show reduced virulence. …”
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Antimicrobial Resistance Associated with Mass Gatherings: A Systematic Review by Linda Tong Pao, Mohamed Tashani, Catherine King, Harunor Rashid, Ameneh Khatami

“…Carriage of <i>Streptococcus pneumoniae</i> isolates non-susceptible to one or more antibiotics was also shown to increase from pre-Hajj to post-Hajj. …”
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Application of Metagenomic Next-Generation Sequencing in the Diagnosis of Infectious Keratitis by Xin-Yu Pan, Meng Wang, Yi-Dan Xu, Lin-Nong Wang

“…Filamentous fungi represented by Fusarium and Aspergillus were the most common, followed by bacteria such as Pseudomonas aeruginosa, Streptococcus pneumoniae, viruses (Herpes Simplex Virus/Varicella-Zoster Virus), and parasites. …”
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Detection of Eight Respiratory Bacterial Pathogens Based on Multiplex Real-Time PCR with Fluorescence Melting Curve Analysis by Liuyang Hu, Bing Han, Qin Tong, Hui xiao, Donglin Cao

“…Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Pseudomonas aeruginosa, and Mycobacterium tuberculosis are primary respiratory bacterial pathogens contributing to morbidity and mortality in developing countries. …”
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Resultados de la realización del hemocultivo al ingreso hospitalario en pacientes con neumonía adquirida en la comunidad by Iris González Morales, María Caridad Fragoso Marchante, Luís Alberto Corona Martínez

“…<br /><strong>Resultados:</strong> en solo cinco pacientes el examen arrojó un resultado positivo (9,6 % de los casos); en un solo caso con cultivo positivo se aisló Streptococcus pneumoniae; en el resto fueron aislados Staphylococcus aureus y Klebsiella pneumoniae. …”
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Why Does Pnemococcus Kill? by Yves Bergeron, Michel G Bergeron

“…Acute lower respiratory tract infections remain the most common cause of death due to infection worldwide, and Streptococcus pneumoniae is responsible for approximately 30% of all cases of community-acquired pneumonia. …”
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A Case of Waterhouse-Friderichsen Syndrome Resulting from an Invasive Pneumococcal Infection in a Patient with a Hypoplastic Spleen by Kazumasa Emori, Nobuhiro Takeuchi, Junichi Soneda

“…The following day, blood cultures revealed the presence of Streptococcus pneumoniae. An autopsy revealed a hypoplastic spleen and a bilateral adrenal hemorrhage, indicating acute adrenal insufficiency caused by sepsis. …”
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Bacteriology and pathological anatomy of pneumonias in monkeys by V. A. Kalashnikova, N. S. Rudenko

“…Staphylococci (23.8%) prevailed among gram-positive bacteria, Escherichia coli (32.1%) – among gram-negative bacteria. Streptococcus pneumoniae made up 0.3%. Based on data from bacteriological tests, the proportion of pneumonias of undetermined etiology was 0.7%. …”
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Modeling and simulation of distribution and drug resistance of major pathogens in patients with respiratory system infections by Li Yang, Ermin Liang, Yali Gao

“…Results The most common pathogens were Streptococcus pneumoniae (30%), Haemophilus influenzae (20%), Pseudomonas aeruginosa (15%), Staphylococcus aureus (10%) and Klebsiella pneumoniae (10%). …”
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Autosplenectomy in a Patient with Paroxysmal Nocturnal Hemoglobinuria (PNH) by Ethan Burns, Kartik Anand, Gonzalo Acosta, Malcolm Irani, Betty Chung, Abhishek Maiti, Ibrahim Ibrahim, Lawrence Rice

“…He had recurrent episodes of sepsis due to dialysis line infections from poor hygiene, and blood cultures had been positive for multiple organisms including Staphylococcus aureus, Enterococcus faecalis, and Streptococcus pneumoniae. The patient’s peripheral blood smears since the age of 14 years demonstrated Howell–Jolly bodies in conjunction with thrombocytopenia and hemolytic anemia, but abdominal ultrasonography reported a normal appearing spleen. …”
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Overview of Community-Acquired Pneumonia and the Role of Inflammatory Mechanisms in the Immunopathogenesis of Severe Pneumococcal Disease by Helen C. Steel, Riana Cockeran, Ronald Anderson, Charles Feldman

“…Despite the implementation of national pneumococcal polyvalent vaccine-based immunisation strategies targeted at high-risk groups, Streptococcus pneumoniae (the pneumococcus) remains the most common cause of CAP. …”
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Dynamic analysis of the epidemiology and pathogen distribution of bronchoalveolar lavage fluid in children with severe pulmonary infection: a retrospective study by Muchun Yu, Mingchao Li, Huiqing Sun

“…The predominant cocci identified in this study were Streptococcus pneumoniae and Staphylococcus aureus. The primary fungi included Candida albicans and Aspergillus fumigatus, which showed significant differences (p < 0.05). …”
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