Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases by Sandipan Dasgupta, Subhasundar Maji, Sanjay Dey, Moitreyee Chattopadhyay, Ananya Chanda, Satarupa Acharjee, Kousik Santra, Kazi Asraf Ali

“…For example, graphene oxide-based nanocomposites improve penetration of the skin’s stratum corneum, facilitating deeper drug delivery. …”
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Book spreaders in the towns of Samogitian principality in the XVIII century by Elmantas Meilus

“…The mentioned evidence proves that by the second half of the 18th century, a social stratum of book consumers had developed in Samogitia. …”
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Moving to lower-poverty neighborhoods offers broad benefits for children with asthma, regardless of sex or other baseline characteristics by Torie L. Grant, MD, MHS, Laken C. Roberts Lavigne, PhD, MPH, Craig Evan Pollack, MD, MHS, Pete Cimbolic, BA, Susan Balcer-Whaley, MPH, Roger D. Peng, PhD, Elizabeth C. Matsui, MD, MHS, Corinne A. Keet, MD, PhD

“…Separately, these models were then stratified by sex, age, body mass index, allergic sensitization, asthma severity, and stress before the move to estimate stratum-specific odds ratios for moving. Results: Participants broadly experienced a postmove reduction in odds of an exacerbation and maximum symptom days. …”
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Development and Characterization of a Hydrogel Containing Chloramphenicol-Loaded Binary Ethosomes for Effective Transdermal Permeation and Treatment Acne in Rat Model by Liu RJ, Li M, Zhu Q, Liu HY, Zhang XX, Han XY, Yu MJ, Zhou JW, Han CY

“…CLSM and ATR-FTIR confirm that loading CAM into a binary ethosomes enables drugs to pass more easily through the stratum corneum. In vivo testing and histopathological analysis demonstrated that the CAM-BE hydrogel significantly inhibited swelling in the rat auricle, compared to both the free CAM hydrogel and adapalene hydrogel.Conclusion: With their strong anti-inflammatory properties and improved skin penetration, binary ethosomes could be a viable new CAM delivery method. …”
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In Vivo Plasticity at Hippocampal Schaffer Collateral-CA1 Synapses: Replicability of the LTP Response and Pharmacology in the Long-Evans Rat by A. Ahnaou, E. White, R. Biermans, N. V. Manyakov, W. H. I. M. Drinkenburg

“…The present study was undertaken in Long-Evans (LE) rats, a strain of rat commonly used in cognitive behavioral tests, to (1) compare three LTP tetanisation protocols, namely, the high-frequency stimulation (HFS), the theta-burst stimulation (TBS), and the paired-pulse facilitation (PPF) at the Schaffer collateral-CA1 stratum radiatum synapse and to (2) assess sensitivity to acute pharmacology. …”
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Research on the deformation mechanism and law caused by the influence of seepage on foundation pit dewatering by Qingyuan Yang, Song Chen

“…It reveals that the precipitation curve outside the foundation pit under the influence of seepage around the foundation pit presents the characteristics, and puts forward the calculation formula of surface settlement change outside the pit caused by partially penetrating well precipitation in the completely decomposed granite stratum. The calculation results of the theoretical formula are in good agreement with the experimental results, which has good accuracy and applicability. (2) The surface settlement outside the pit caused by dewatering in the foundation pit is mainly concentrated in the surrounding seepage area, and the change value of surface settlement outside the pit caused by double well dewatering is 2∼3 times greater than that caused by single well dewatering. …”
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Mineralized Granitic Porphyry of the Yangla Copper Deposit, Western Yunnan, China: Geochemistry of Fluid Inclusions and H-O, S, and Pb Isotopes by Xinfu Wang, Bo Li, ShenJin Guan, Olivier Nadeau, Guo Tang

“…The ore bodies are strictly controlled by the stratum, pluton, and structure, which are layered, lens, and vein-like within the contact or fracture zone of the pluton and surrounding rock. …”
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Acute effect of exercise with or without the integration of cooperative activities on inhibitory control in preadolescent school children by Melanie Berger, Markus Gerber, Sebastian Ludyga

“…Methods We examined a subsample of the NEXOS2 RCT. 100 children (11 ± 0.7 years) were allocated (stratum: school class) to a group performing exercise demanding cooperation (EX+CO, n = 29), a group performing exercise without cooperation (EX, n = 35), and a control group watching a video (CON, n = 36). …”
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Characteristics of Hydrogels as a Coating for Microneedle Transdermal Delivery Systems with Agomelatine by Monika Wojtyłko, Ariadna B. Nowicka, Anna Froelich, Mirosław Szybowicz, Tobiasz Banaszek, Dorota Tomczak, Wiesław Kuczko, Radosław Wichniarek, Irena Budnik, Barbara Jadach, Oliwia Kordyl, Antoni Białek, Julia Krysztofiak, Tomasz Osmałek, Dimitrios A. Lamprou

“…However, transdermal delivery requires crossing the <i>stratum corneum</i> barrier. For this purpose, the use of microneedles may increase the efficiency of administration. …”
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Umbilical Cord Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Modulate Skin Matrix Synthesis and Pigmentation by Kee LT, Foo JB, How CW, Nur Azurah AG, Chan HH, Mohd Yunus MH, Ng SN, Ng MH, Law JX

“…However, when it was applied topically, UC-MSC-sEVs failed to penetrate the skin barrier and remained localized within the stratum corneum layer even after 18 hours.Conclusion: These results highlight the potential of UC-MSC-sEVs in stimulating HDF proliferation, regulating ECM synthesis, and reducing melanin production. …”
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When specific exercise is more effective than medication - Sensorimotor training is currently the most promising option to treat and prevent chemotherapy-induced peripheral neuropa... by Fiona Streckmann, Maryam Balke, Céline Hammadou, Bianca Schmidli, Oliver Faude, Sarah Koch

“…Secondary end points included subjective neuropathy symptoms, balance control, physical activity levels, quality of life, and clinical outcome. For cross-stratum evaluations, the Mantel-Haenszel test (MH) was used, and within individual strata, Fisher exact test was used for analysis. …”
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Le réseau hydraulique à Pompéi (Italie) de l’époque des Samnites à Auguste (fin ive-fin ier s. av. J.-C.) by Federico Giletti

“…While the latter type appears equally in both private and public contexts, the burrow cistern by contrast differs in that it is excavated entirely into the lava stratum and has been demonstrated, as far as we currently know, only on the main outcrops of the lava plateau, such as on the rocky crest of the southern drop in height below insula 2 of Regio VIII.While the type of cistern with a burrow or bainhole seems to have been inspired by models already widespread in Punic-Carthaginian sites in Africa and on the islands and in the Magna-Greek area, cases of cisterns with a burrow collected to several arms primarily bear strong similarities to Etruscan-Latian examples, as does the technique of drainage tunnels entirely excavated in the geological bank and the custom of digging deep artesian wells. …”
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