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3061
Epigene functional diversity: isoform usage, disordered domain content, and variable binding partners
Published 2025-02-01“…This specialized group of proteins is responsible for controlling the organization of genomic DNA in a cell-type specific fashion, controlling normal development in a spatial and temporal fashion. …”
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3062
Conventional and complementary alternative medicine therapies for renal anemia: a literature review
Published 2025-01-01“…Renal anemia stems mainly from chronic inflammation with elevated hepcidin levels, iron deficiency, and reduced red blood cell lifespan. …”
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3063
Transcriptome analysis of ovarian cancer uncovers association between tumor-related inflammation/immunity and patient outcome
Published 2025-02-01“…With the rapid development of PD-1/PD-L1, CTLA-4, oncolytic viruses, cancer vaccines, adoptive cell therapy, etc., tumor immunotherapy has provided new opportunities for the treatment of ovarian cancer.MethodsThis study used comprehensive transcriptome analysis across multiple databases to gather gene transcripts and clinical features of normal ovarian samples and tissue samples from ovarian cancer. …”
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3064
Grand Challenges at the Interface of Engineering and Medicine
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3065
Baicalin: a potential therapeutic agent for acute kidney injury and renal fibrosis
Published 2025-01-01“…Baicalin’s therapeutic effects are achieved through various pathways, including antioxidant, anti-inflammatory, antifibrosis, and regulation of apoptosis and cell proliferation. Besides, we also hope this review may give some enlightenment for treating AKI and renal fibrosis in clinical practice.…”
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3066
UGCG promotes chemoresistance and breast cancer progression via NF-κB and Wnt/β-catenin pathway activation
Published 2025-02-01“…Gain- and loss-of-function experiments demonstrated that UGCG enhanced the proliferation, metastasis, and stemness of breast cancer cells. Furthermore, treatment with paclitaxel or docetaxel resulted in increased UGCG expression, which in turn reduced chemotherapy-induced cell apoptosis and improved drug resistance and metastatic capabilities. …”
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3067
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3068
TRANSFER OF ARGOS-LIKE AND ATEXPA10 GENES INTO NONTRANSGENIC FORMS OF TOBACCO AND PHENOTYPIC EFFECTS OF THEIR CONSTITUTIVE EXPRESSION
Published 2014-12-01“…It led to an increase in the sizes of their leaves and stems. Organs of both transgenic and hybrid plants were enlarged due to the enlargement of individual cells. …”
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3069
Morpho-phylogenetic evidence reveals Pseudolomaantha thailandica gen. et sp. nov. and Submultiguttulispora multiseptata gen. et sp. nov. in Chaetosphaeriaceae
Published 2025-01-01“…Pseudolomaantha thailandica gen. et sp. nov. is characterized by a sporidesmium-like asexual morph with macronematous, mononematous conidiophores; monoblastic conidiogenous cells, and pyriform to obclavate, rostrate conidia bearing an apical appendage. …”
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3070
Integrated Bioinformatics and Experimental Approaches Identified the Role of NPPA in the Proliferation and the Malignant Behavior of Breast Cancer
Published 2021-01-01“…The NPPA expression is downregulated in breast cancer patients, independent of the ER status, PR status, stemness score, and immune infiltrating condition. …”
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3071
Endothelial SHANK3 regulates tight junctions in the neonatal mouse blood-brain barrier through β-Catenin signaling
Published 2025-02-01“…Here we report that SHANK3, an ASD-risk gene, expresses in the BBB-forming brain endothelial cells (BECs) and regulates tight junctional (TJ) integrity essential for BBB’s barrier function. …”
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3072
Photosynthetic performance and carbon metabolism in the ear organs of oats under drought stress
Published 2025-01-01“…The results showed that stomatal tissues were present in both the inner and outer epidermis in the glumes and lemmas, and chloroplasts existed in the cells of both ear organs. Compared to CK-14, the absolute water content was significantly decreased in the flag leaves, stems, and seeds under DS-14, while drought stress did not significantly affect the water status of the glumes, lemmas, and peduncles. …”
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3073
Hemodynamic disturbance and mTORC1 activation: Unveiling the biomechanical pathogenesis of thoracic aortic aneurysms in Marfan syndrome
Published 2025-02-01“…We uncovered that activation of the mTOR complex 1 (mTORC1) within smooth muscle cells, instigated by the oscillatory wall shear stress (OSS) that stems from disturbed flow (DF), is a catalyst for TAA progression. …”
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3074
Cadmium sulfide (CdS) nanoparticles and Cd2+ accumulated by Portulaca oleracea L. using a hydroponic system: Constructed wetland perspective
Published 2025-01-01“…CdS NPs aggregates were identified within the plant cells in root and shoot tissues using transmission electron microscopy (TEM). …”
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3075
Ticam2 ablation facilitates monocyte exhaustion recovery after sepsis
Published 2025-01-01“…Abstract Sepsis is a leading cause of death worldwide, with most patient mortality stemming from lingering immunosuppression in sepsis survivors. …”
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3076
Advanced surgical techniques and considerations in carotid body tumor management: insights from a cohort study
Published 2025-02-01“…These neoplasms originate from the aggregation of chemoreceptor cells in the cervical area, stemming from the neural crest during embryonic development. …”
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3077
Hepatotoxic Effects of Gaseous Sulfur Dioxide (SO₂), Nitrogen Dioxide (NO₂), and Their Mixture on Sea Bass (Centropristis striata): Hematological, Biochemical and Genotoxic Studies...
Published 2024-12-01“…This study meticulously explores the intricate hepatotoxic effects stemming from acute exposure to gaseous sulfur dioxide (SO2), nitrogen dioxide (NO2), and their amalgamation on sea bass (Centropristis striata). …”
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3078
Benefits of Immobilized Bacteria in Bioremediation of Sites Contaminated with Toxic Organic Compounds
Published 2025-01-01“…One typical reason for this is the high toxicity of xenobiotics present in large concentrations, stemming from the vulnerability of bacteria introduced to a contaminated site. …”
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3079
Trends in blood transfusion and causes of blood wastage: a retrospective analysis in a teaching hospital
Published 2025-01-01“…Conclusions The study highlights that blood wastage often stems from human error or improper storage conditions. …”
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3080
Nanoparticles for Biomedical Use Derived from Natural Biomolecules: Tannic Acid and Arginine
Published 2025-01-01“…Abundant numbers of functional groups, -OH, -NH<sub>2</sub>, and -COOH stemming from TA and ARG constituent confirmed by FT-IR analysis. …”
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