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3001
Combined BPA and DIBP Exposure Induced Intestinal Mucosal Barrier Impairment Through the Notch Pathway and Gut Microbiota Dysbiosis in Mice
Published 2025-01-01“…The results indicated that the combination of BPA and DIBP exposure resulted in a reduction of beneficial flora, an increase in D-Lac levels (136 ± 14 μmol/L), an increase in intestinal permeability, activation of the notch pathway, and a decline in intestinal stem cells (ISCs) to goblet cells, compared to single-exposure sources. …”
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3002
Development of Prevascularized Synthetic Block Graft for Maxillofacial Reconstruction
Published 2025-01-01“…Conversely, the co-culture with mesenchymal stem cells did not yield similar results. Combining ECs and aHOBs in the CMP scaffold offers a promising approach to developing prevascularized grafts for cranio-maxillofacial reconstruction. …”
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3003
A prognostic signature of Glutathione metabolism-associated long non-coding RNAs for lung adenocarcinoma with immune microenvironment insights
Published 2025-02-01“…Additionally, variations were noted in the IC50 values for key lung cancer medications such as Cisplatin, Docetaxel, and Paclitaxel. In vitro cell experiment results showed that AL162632.3 was markedly upregulated, while AC026355.2 tended to be downregulated across these cell lines. …”
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3004
Phytochemical and Biological Investigations of Crude Extracts of <i>Astragalus pisidicus</i>
Published 2024-12-01“…<b>Conclusions</b>: <i>A. pisidicus</i> elicited apoptotic cell death in cancer cells selectively by the activation of caspases and subsequent DNA fragmentation and may serve as a novel source of an apoptosis-inducing anticancer drug.…”
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3005
Cardioprotective effects of hUCMSCs-Exosi-EGR1 MN patch in MI/RI by modulating oxidative stress and mitophagy
Published 2025-04-01“…In an effort to address the detrimental effects of myocardial ischemia/reperfusion injury (MI/RI), this study introduces a novel therapeutic strategy that involves a microneedle (MN) patch loaded with exosomes derived from human umbilical cord mesenchymal stem cells (hUCMSCs) and carrying small interfering RNA (siRNA) targeting early growth response-1 (EGR1). …”
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3006
Activation of Sphingosine 1-Phosphate Receptor 1 Enhances Hippocampus Neurogenesis in a Rat Model of Traumatic Brain Injury: An Involvement of MEK/Erk Signaling Pathway
Published 2016-01-01“…Among sphingosine 1-phosphate receptors (S1PRs) family, S1PR1 has been shown to be the most highly expressed subtype in neural stem cells (NSCs) and plays a crucial role in the migratory property of NSCs. …”
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3007
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage
Published 2021-01-01“…In patients with subarachnoid hemorrhage (SAH), the damage of the blood-brain barrier (BBB) can be life-threatening. Mesenchymal stem cells are widely used in clinical research due to their pleiotropic properties. …”
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3008
Bioceramic Surface Topography Regulating Immune Osteogenesis
Published 2025-01-01“…Further researches show that macrophage of the large spacing micro-groove structure can promote the osteogenic differentiation of bone mesenchymal stem cells, which can benefit osteogenesis and osteointegration. …”
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3009
Tailoring and characterization of bioactive graft material for alveolar bone preservation and regeneration in fresh extraction sockets of dog model
Published 2025-01-01“…Tailored amorphous multiporous bioactive glass (TAMP -BG) was prepared and characterized for bioactivity and response of human alveolar bone marrow mesenchymal stem cells (hABMSCs). Extraction sockets of twenty-two male mongrel dogs received TAMP-BG in the right side around implant in the distal socket of the mandibular fourth premolar (P4), while the adjacent empty mesial socket of the same tooth was filled with the same graft. …”
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3010
TiO2 Nanocoatings with Controllable Crystal Type and Nanoscale Topography on Zirconia Implants to Accelerate Bone Formation
Published 2022-01-01“…In addition, in vitro cytocompatibility and osteogenic potential performance of the coatings were evaluated by human bone marrow mesenchymal stem cells (hBMSCs), and in vivo osseointegration performance was assessed in a rat femoral condyle model. …”
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3011
Physiological and transcriptome analysis of sex-specific responses to cadmium stress in poplars
Published 2025-01-01“…Over 70 % of the Cd was distributed in the cell wall fraction of roots, stems, and leaves, with the majority accumulating in the roots. …”
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3012
Mucosa-Associated Lymphoid Tissue Lymphoma of the Larynx
Published 2020-01-01“…Mucosa-associated lymphoid tissue (MALT) lymphomas are a subtype of non-Hodgkin lymphoma stemming from marginal zone B-cells. In this case report, we present two patients with an extremely rare localization of MALT lymphoma to the larynx. …”
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3013
Taxonomical enumeration of traditional, socio-economic importance plant of Dharbai
Published 2025-03-01“…In anatomical observations of the leaf cross-section, a single-layer epidermis, hypodermis with sclerenchyma cells, and vascular bundles with phloem and xylem are identified. …”
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3014
An increased proportion of transgenic plants in the progeny of rapeseed (<i>Brassica napus</i> L.) transformants
Published 2021-04-01“…Thus, both transformed and non-transformed cells were involved in the formation of gametes in T0 plants. …”
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3015
Fibroblasts in rheumatoid arthritis: novel roles in joint inflammation and beyond
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3016
Potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with SARS-CoV-2 infection and bacterial complications: Our recent exp...
Published 2025-02-01“…The analysis shows that the photodynamic effect of long-wavelength polycationic photosensitizers suppresses the tumor process (including the destruction of cancer stem cells), SARS-CoV-2 coronavirus infection, Gram-positive and Gram-negative bacteria, including those that can cause pneumonia. …”
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3017
Long-term real-world evidence of CPX-351 of high-risk patients with AML identified high rate of negative MRD and prolonged OS
Published 2025-02-01“…We also observed a trend toward a better median OS in patients who underwent hematopoietic stem cell transplantation with MRD <10–3 (not reached vs 26.0 months; P = .06). …”
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3018
Non-Drug and Non-Invasive Therapeutic Options in Alzheimer’s Disease
Published 2025-01-01“…Singly or as an applied technique to change the permeability of the blood–brain–barrier (BBB), FUS and TPS have demonstrated the benefits of use in treating AD in animal and human studies. Adipose-derived stem Cells (ADSCs), gene therapy, and many other alternative methods (diet, sleep pattern, physical exercise, nanoparticle delivery) are also new potential treatments since multimodal approaches represent the modern trend in this disorder research therapies.…”
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3019
Sustained slow-release TGF-β3 in a three-dimensional-printed titanium microporous scaffold composite system promotes ligament-to-bone healing
Published 2025-04-01“…In vitro, the composite system exhibited good biocompatibility and was beneficial for the adhesion and proliferation of bone marrow mesenchymal stem cells (BMSCs), which showed high growth activity. …”
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3020
Influence of advanced maternal age and gestational age on the morphology of human placenta
Published 2024-01-01“…Due to its availability and high content of stem cells and growth factors, placenta tissue has found its application in regenerative medicine. …”
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