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Diagnosis and Management of Atypical Chronic Myeloid Leukemia with a t(2;13)(q33;q12) Translocation
Published 2022-01-01“…Allogeneic hematopoietic stem cell transplant is likely the preferred treatment, but this can be limited by patient psychosocial support, age, concomitant medical conditions, and availability of an appropriate donor. …”
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Evaluating the Role of Wnt Signal Transduction in Promoting the Development of the Heart
Published 2007-01-01“…These molecules initiate several signal transduction pathways: the canonical Wnt, Wnt/Ca2+, and Wnt/planar cell polarity pathways. Wnt proteins have major impact on embryonic development, tumor progression, and stem cell differentiation. …”
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2487
Serum Cytokine Profile in a Patient Diagnosed with Dysferlinopathy
Published 2017-01-01Get full text
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Applications of Amniotic Membrane in Ophthalmology – New Perspectives in the Treatment of Eye Diseases
Published 2024-08-01“…In ophthalmology, amniotic membrane is used in the treatment of corneal ulcers, limbal stem cell deficiency, burns, strabismus, glaucoma, and neoplastic changes. …”
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Optimized gene transduction in human lung organoids: A high-efficiency method for advanced research applications
Published 2025-02-01“…Abstract Human induced pluripotent stem cell (iPSC)-derived lung organoids, engineered to carry targeted genes, offer a robust platform for investigating mechanistic insights in lung research. …”
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Circ_0044516 Regulates miR-136/MAT2A Pathway to Facilitate Lung Cancer Development
Published 2021-01-01“…We also found that cancer stem cell properties were restrained by silencing circ_0044516 in A549 and SPC-A1 cells. …”
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In Vitro Evaluation of Bioactivity of Chemically Deposited Hydroxyapatite on Polyether Ether Ketone
Published 2015-01-01“…The mesenchymal stem cell proliferation result showed better cells proliferation on the treated layer in comparison with untreated PEEK. …”
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Hemorrhagic Spinal Schwannoma in Thoracolumbar Area with Total Paraplegia
Published 2019-01-01Get full text
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2493
Cellular Plasticity in Prostate Cancer Bone Metastasis
Published 2015-01-01“…An electronic search was performed using PubMed for studies that have examined the differential expression of epithelial, mesenchymal, and stem cell markers in human PC bone metastasis tissues. …”
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Latest Approved Therapies for Metastatic Melanoma: What Comes Next?
Published 2013-01-01“…Eventually, multidisciplinary approaches are still requested (e.g., genomics for personalized medicine, nanomedicine to overcome low free-drug bioavailability and targeting, systematic search of “melanoma stem cells” to enhance the prognosis and develop more valuable theranostics). …”
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Prenatal Brain Damage in Preeclamptic Animal Model Induced by Gestational Nitric Oxide Synthase Inhibition
Published 2011-01-01Get full text
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Vitamin A: A Key Inhibitor of Adipocyte Differentiation
Published 2023-01-01“…Nevertheless, the functional role of RA in early tissue development and stem cell differentiation, including in adipose tissue, remains unclear. …”
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Immune infiltrate populations within distinct tumor immune microenvironments predictive of immune checkpoint treatment outcome
Published 2025-01-01“…We have previously validated signatures predictive of checkpoint inhibitor efficacy which distinguish immunomodulatory, mesenchymal stem-like, and mesenchymal phenotypes. Here we use twenty tumor types (7162 samples) to identify potentially conserved immune biology within these TIME spaces, genes co-expressed across distinct cell types involved these immune processes, and the association of these signatures with ICI response. …”
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Mitotic chromatin marking governs the segregation of DNA damage
Published 2025-01-01“…We propose that this mechanism may help preserve the integrity of stem cell compartments during asymmetric cell divisions.…”
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Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon
Published 2017-01-01“…On the other hand, “cancer disease” is the representation of an abnormal state of the cell that might happen in the stem cells of an adult person, in which the mechanism for joint gene regulating of differentiation, proliferation, cell invasion, and migration could be reactivated in an entirely inappropriate context.…”
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