Translocation (6;15)(q12;q15): A Novel Mutation in a Patient with Therapy-Related Myelodysplastic Syndrome by Saba F. Ali, Rebecca J. Sonu, Denis M. Dwyre, Brian A. Jonas, Hooman H. Rashidi

“…Patients with t-MDS, a group of heterogeneous stem cell related disorders resulting as a latent complication of cytotoxic and/or radiation therapy, generally tend to have a poorer prognosis than de novo MDS. …”
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Rapid iPSC-derived neuromuscular junction model uncovers motor neuron dominance in amyotrophic lateral sclerosis cytopathy by Hsiao-Chien Ting, Yun-Ting Guo, Hong-Lin Su, Yu-Shuan Chen, Shinn-Zong Lin, Horng-Jyh Harn, Chia-Yu Chang

“…Although human induced pluripotent stem cell (iPSC)-derived models have advanced NMJ research, their application is constrained by challenges such as limited differentiation efficiency, lengthy generation times, and cryopreservation difficulties. …”
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Distinct Roles of Wnt/β-Catenin Signaling in the Pathogenesis of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis by Juan Shi, Feng Li, Meihui Luo, Jun Wei, Xiaoming Liu

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The synthesis and research of the naphthalimide G-quadruplex probe targeting hybrid G4s by Lilin Gan, Wenzheng Luo, Qian Cheng, Shanke Wan, Min Wu, Mingqi Wang, Enming Luo, Xianjin Luo, Shuo Li

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Prooxidant-Antioxidant Balance in Umbilical Cord Blood of Infants with Meconium Stained of Amniotic Fluid by Mohammad Hassan Arjmand, Farhat Ahmad Shah, Masoud Saleh Moghadam, Fatemeh Tara, Amin Jalili, Mojtaba Mosavi Bazaz, Daryoush Hamidi Alamdari

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Intraventricular Neurilemmoma (Schwannoma): Shall GFAP Immunostaining Be Regarded as a Histogenetical Tag or as a Mere Histomimetical Trait? by Miguel Fdo. Salazar, Martha Lilia Tena Suck, Daniel Rembao Bojórquez, Citlaltepetl Salinas Lara

“…As previously advised by some authors, neoplastic transformation from a multipotent stem cell may explain the occasional finding of these tumours in unconventional intracranial compartments.…”
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Application of Three-Dimensional Imaging to the Intestinal Crypt Organoids and Biopsied Intestinal Tissues by Yun Chen, Ya-Hui Tsai, Yuan-An Liu, Shih-Hua Lee, Sheng-Hong Tseng, Shiue-Cheng Tang

“…The 3D structure of the crypt organoids from the intestinal stem cell culture and intestinal tissues from the donors and recipients after intestinal transplantation was observed using a 3D imaging system and compared with 2D histopathology and immunohistochemistry. …”
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Corneal Epithelial Thickness Mapping: A Major Review by Mohammad-Ali Abtahi, Amir Hushang Beheshtnejad, Golshan Latifi, Marjan Akbari-Kamrani, Sadegh Ghafarian, Ahmad Masoomi, Seyed Ali Sonbolastan, Hamidreaza Jahanbani-Ardakani, Mehrnaz Atighechian, Laleh Banan, Hosein Nouri, Seyed-Hossein Abtahi

“…We also reviewed ETM data in several corneal disorders, including keratoconus, corneal dystrophies, recurrent epithelial erosion, herpes keratitis, keratoplasty, bullous keratopathy, carcinoma in situ, pterygium, and limbal stem cell deficiency. The available data on the potential role of ETM in indicating refractive surgeries, planning the procedure, and assessing postoperative changes are reviewed. …”
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Therapeutic potential of SOX family transcription factors in osteoarthritis by Yue Huang, Zhuo Wang

“…Non-coding RNA may play a role in the onset and progression of osteoarthritis by modulating various SOX family members, including SOX2, SOX4, SOX5, SOX6, SOX8, SOX9 and SOX11.Conclusion SOX9 has the capability of mitigating the onset and progression of osteoarthritis through means such as medication therapy, stem cell therapy, recombinant adeno-associated virus (rAAV) vector therapy, physical therapy and other approaches.…”
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Imaging cell spheroid clusters: An MRI protocol for non-invasive standardized characterization by Rebecca Wißmann, Petros Martirosian, Marina Danalache, Gerd Grözinger, Fritz Schick, Stefanie Elser

“…Despite its limited spatial resolution, this method adeptly reveals information about the composition and vitality of stem cell and cancer spheroids and their micro-environment in a non-invasive manner. …”
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Oncolytic Virotherapy for Hematological Malignancies by Swarna Bais, Eric Bartee, Masmudur M. Rahman, Grant McFadden, Christopher R. Cogle

“…For high-risk disease, hematopoietic stem cell transplant (HCT) can be used. However, in the setting of autologous HCT, relapse due to contamination of the autograft with cancer cells remains a major challenge. …”
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Bortezomib, thalidomide, and dexamethasone versus bortezomib, lenalidomide, and dexamethasone in transplant-eligible newly diagnosed multiple myeloma: a systemic review and meta-an... by Yin-Che Wang, Cheng-Hsien Lin, Yu-Chen Su, Chieh-Lin Jerry Teng

“…The primary endpoints were response rates after induction therapy and the incidence of a need for autologous hematopoietic stem cell transplantion (auto-HSCT) between the groups. …”
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Probing the Hepatic Progenitor Cell in Human Hepatocellular Carcinoma by Shu-Qin Jia, Jian-Jun Ren, Pei-De Dong, Xing-Kai Meng

“…Objective. The intrahepatic stem cells, also known as hepatic progenitor cells (HPCs), are able to differentiate into hepatocytes and bile duct epithelia. …”
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Spinal Fusion in the Next Generation: Gene and Cell Therapy Approaches by Marta Barba, Claudia Cicione, Camilla Bernardini, Vincenzo Campana, Ernesto Pagano, Fabrizio Michetti, Giandomenico Logroscino, Wanda Lattanzi

“…The improved knowledge of both mesenchymal stem cell biology and osteogenic molecules allowed their use in regenerative medicine, representing attractive approaches to achieve bone regeneration also in spinal surgery applications. …”
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Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets by Claire Vinel, James Boot, Weiwei Jin, Nicola Pomella, Alexandra Hadaway, Charles Mein, Nicolae Radu Zabet, Silvia Marino

“…Results We have leveraged SYNGN, an experimental pipeline enabling the syngeneic comparison of glioblastoma stem cells and expanded potential stem cell (EPSC)-derived neural stem cells to identify regulatory features driven by chromatin remodelling specifically in glioblastoma stem cells. …”
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p38 MAPK Endogenous Inhibition Improves Neurological Deficits in Global Cerebral Ischemia/Reperfusion Mice by Kun Hou, Zhi-cheng Xiao, Hai-Long Dai

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Traumatic Brain Injury Promotes Neurogenesis and Oligodendrogenesis in Subcortical Brain Regions of Mice by Olga Astakhova, Anna Ivanova, Ilia Komoltsev, Natalia Gulyaeva, Grigori Enikolopov, Alexander Lazutkin

“…Besides inducing neurodegeneration, TBI alters stem cell activity and neurogenesis within primary neurogenic niches. …”
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Subtype-specific role for Jagged1 in promoting or inhibiting breast tumor formation by Wen-Cheng Chung, Wei Wang, Lavanya Challagundla, Charles D. Moore, Sean E. Egan, Keli Xu

“…Here we report that deletion of Jagged1 in the mammary epithelium of virgin mice led to expansion of the mammary stem cell (MaSC) compartment and defective luminal differentiation associated with decreased expression of the progesterone receptor (PR). …”
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Single cell RNA sequencing improves the next generation of approaches to AML treatment: challenges and perspectives by Zahra Khosroabadi, Samaneh Azaryar, Hassan Dianat-Moghadam, Zohreh Amoozgar, Mohammadreza Sharifi

“…ScRNA-seq allows the identification of quiescent stem-like cells, and leukemia stem cells responsible for resistance to therapeutic approaches and relapse after treatment. …”
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The improved prognosis of <i>FLT3</i>-internal tandem duplication but not tyrosine kinase domain mutations in acute myeloid leukemia in the era of targeted therapy: a real-world st... by Matthew Schwede, Gladys Rodriguez, Vanessa E. Kennedy, Solomon Henry, Douglas Wood, Gabriel N. Mannis, Ravindra Majeti, Jonathan H. Chen, Eran Bendavid, Tian Yi Zhang

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