Prominosomes - a particular class of extracellular vesicles containing prominin-1/CD133? by Jana Karbanová, Kristina Thamm, Christine A. Fargeas, Ilker A. Deniz, Aurelio Lorico, Denis Corbeil

“…We will further discuss the molecular and cellular characteristics of prominin-1, notably those that have a direct effect on the release of prominin-1+ EVs, a process that might be directly implicated in donor cell reprogramming of stem and cancer stem cells. Prominin-1+ EVs also mediate intercellular communication during embryonic development and adult homeostasis in healthy individuals, while disseminating biological information during diseases. …”
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Challenging a Misnomer? The Role of Inflammatory Pathways in Inflammatory Breast Cancer by Riley J. Morrow, Nima Etemadi, Belinda Yeo, Matthias Ernst

“…The role of the tumor microenvironment, through tumor-associated macrophages, infiltrating lymphocytes, and cancer stem cells is also discussed, suggesting that these tumor extrinsic factors may help account for the differences in behavior between inflammatory breast cancer and noninflammatory breast cancer. …”
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Estrogen-dependent activation of TRX2 reverses oxidative stress and metabolic dysfunction associated with steatotic disease by Alfredo Smiriglia, Nicla Lorito, Marina Bacci, Angela Subbiani, Francesca Bonechi, Giuseppina Comito, Marta Anna Kowalik, Andrea Perra, Andrea Morandi

“…In this study, we utilized preclinical in vitro models—immortalized cell lines and hepatocyte-like cells derived from human embryonic stem cells—exposed to clinically relevant steatotic-inducing agents. …”
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Hippocampal Proliferation Is Increased in Presymptomatic Parkinson’s Disease and due to Microglia by Karlijn J. Doorn, Benjamin Drukarch, Anne-Marie van Dam, Paul J. Lucassen

“…This brain region also contains stem cells that can proliferate. This is a well-regulated process that can, for example, be altered by neurodegenerative conditions. …”
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Current Advances in Pharmacotherapy and Technology for Diabetic Retinopathy: A Systematic Review by Lei Lu, Ying Jiang, Ravindran Jaganathan, Yanli Hao

“…Recently, advancements in pluripotent stem cells technology enable restoration of retinal functionalities after transplantation of these cells into animals with retinal degeneration. …”
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Random antimicrobial peptide mixtures as non-antibiotic antimicrobial agents for cultured meat industry by Idan Yakir, Einav Cohen, Sharon Schlesinger, Zvi Hayouka

“…Here we show that RPMs had no significant impact on mesenchymal stem cells (MSCs) at concentrations that effectively inhibit bacterial growth. …”
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Recent Advances in DNA Systems for In Situ Telomerase Activity Detection and Imaging by Shiyi Zhang, Wenjing Xiong, Shuyue Xu, Ruocan Qian

“…Its activity is pivotal in stem cells and cancer cells but absent in most normal somatic cells. …”
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“TRANSHUMANIZATION” OF MODERN EDUCATION by G. L. ILYIN

“…NBICS combine nanotechnology, biotechnology, IT, cognitive and social sciences, genetic engineering, stem cells, and cloning. These research areas converge and create a cumulative effect. …”
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Phytonanoparticles as novel drug carriers for enhanced osteogenesis and osseointegration by Nandita Suresh, Nebu George Thomas, Matti Mauramo, Tuomas Waltimo, Timo Sorsa, Sukumaran Anil

“…Looking ahead, we identify key research directions, including developing personalized therapies, combination approaches with stem cells or gene delivery, and long-term safety assessments. …”
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Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids by Arun Sridhar, Ingunn Bakke, Shreya Gopalakrishnan, Nimo Mukhtar Mohamud Osoble, Emilie Prytz Hammarqvist, Henrik P. Sahlin Pettersen, Arne Kristian Sandvik, Ann Elisabet Østvik, Marianne Doré Hansen, Torunn Bruland

“…During homeostasis, epithelial renewal is maintained by crypt stem cells and progenitors that cease to divide as they differentiate into mature colonocytes. …”
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Chitosan suitability to adhesion, neuronal differentiation and maturation of hiPSCs compared to Matrigel coated substrates by Sara Grasselli, Donatella Di Lisa, Pier Francesco Ferrari, Sergio Martinoia, Laura Pastorino

“…Human induced pluripotent stem cells (hiPSCs) derived neurons are revolutionising the study of patient-specific conditions. …”
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Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening by Wei Jin, Yexuan Deng, John E. La Marca, Emily J. Lelliott, Sarah T. Diepstraten, Christina König, Lin Tai, Valentina Snetkova, Kristel M. Dorighi, Luke Hoberecht, Millicent G. Hedditch, Lauren Whelan, Geraldine Healey, Dan Fayle, Kieran Lau, Margaret A. Potts, Moore Z. Chen, Angus P. R. Johnston, Yang Liao, Wei Shi, Andrew J. Kueh, Benjamin Haley, Jean-Philippe Fortin, Marco J. Herold

“…We further demonstrate successful in vivo gene editing, using normal and cancer-prone enAsCas12a stem cells to reconstitute the haematopoietic system of wild-type mice. …”
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Systemic and Local Administration of Antimicrobial and Cell Therapies to Prevent Methicillin-Resistant Staphylococcus epidermidis-Induced Femoral Nonunions in a Rat Model by Arianna B. Lovati, Lorenzo Drago, Marta Bottagisio, Matilde Bongio, Marzia Ferrario, Silvia Perego, Veronica Sansoni, Elena De Vecchi, Carlo L. Romanò

“…This study compares the response to S. epidermidis-infected fractures in rats systemically or locally injected with vancomycin or bone marrow mesenchymal stem cells (BMSCs) in preventing the nonunion establishment. …”
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Isthmin 1 is Expressed by Progenitor-Like Cells in the Lung: Phenotypical Analysis of Isthmin 1+ Hematopoietic Stem-Like Cells in Homeostasis and during Infection by Guadalupe Rivera-Torruco, Carolina A. Martínez-Mendiola, Tania Angeles-Floriano, Gustavo Alberto Jaimes-Ortega, José Luis Maravillas-Montero, Rodolfo García-Contreras, Yolanda González, Esmeralda Juárez, Porfirio Nava, Vianney Ortiz-Navarrete, Oscar Medina-Contreras, Paula Licona-Limón, Ricardo Valle-Rios

“…Further characterization of hematopoietic progenitor cells indicated that ISM1+ Lineage- Sca-1+ c-kit+ (ISM1+ LSK) cells are enriched in short-term hematopoietic stem cells (ST-HSCs). Moreover, most Sca-1+ ISM1+ cells express the residence marker CD49a, and this correlated with their localization in the extravascular region of the lung, indicating that ISM1+ cells are lung-resident cells. …”
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Intercellular communication is crucial in the regulation of healthy aging via exosomes by Huifang Sun, Tengyuan Xia, Shuting Ma, Tao Lv, Yuhong Li

“…The hallmarks of aging encompass a variety of molecular categories (genomic, telomeric, and epigenetic), organelles (proteostasis, autophagy, and mitochondria), cellular components (including stem cells), systems (such as intercellular communication and chronic inflammation), and environmental factors (dysbiosis and nutrient sensing). …”
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Activation of Sphingosine 1-Phosphate Receptor 1 Enhances Hippocampus Neurogenesis in a Rat Model of Traumatic Brain Injury: An Involvement of MEK/Erk Signaling Pathway by Yuqin Ye, Zhenyu Zhao, Hongyu Xu, Xin Zhang, Xinhong Su, Yongxiang Yang, Xinguang Yu, Xiaosheng He

“…Among sphingosine 1-phosphate receptors (S1PRs) family, S1PR1 has been shown to be the most highly expressed subtype in neural stem cells (NSCs) and plays a crucial role in the migratory property of NSCs. …”
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Effect of amniotic fluid on hair follicle growth by Gamze Tumentemur, Elif Ganime Aygun, Bulut Yurtsever, Didem Cakirsoy, Ercument Ovali

“…Purpose: Human amniotic fluid stem cells (hAFSCs) have shown significant regenerative potential in treating hair loss, wound healing, and tissue repair. …”
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When to cryopreserve and when to let it go? A systematic review of priorities in wild animal cryobanking by James Edward Brereton, Sarah Louise Spooner, Susan L. Walker, Andrew Mooney, Philippe Wilson, Gabriela F. Mastromonaco, Elena Hunter, Samuel White

“…In terms of cell type, sperm featured most frequently in cryobanking literature, potentially due to its ease of use in animal breeding programmes. Somatic cells and stem cells featured more commonly in more recently published literature. …”
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The Intersection of Epigenetics and Senolytics in Mechanisms of Aging and Therapeutic Approaches by Daiana Burdusel, Thorsten R. Doeppner, Roxana Surugiu, Dirk M. Hermann, Denissa Greta Olaru, Aurel Popa-Wagner

“…Epigenetic reprogramming strategies, such as induced pluripotent stem cells, may further complement senolytics by rejuvenating aged cells. …”
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Developing human upper, lower, and deep lung airway models: Combining different scaffolds and developing complex co-cultures by Rasika S Murkar, Cornelia Wiese-Rischke, Tobias Weigel, Sascha Kopp, Heike Walles

“…We concluded that co-cultivation of primary/stem cells or cell lines has a higher influence on the function of the airway tissue models than the applied scaffolds.…”
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