Toll-Like Receptor-Based Strategies for Cancer Immunotherapy by Saghar Pahlavanneshan, Ali Sayadmanesh, Hamidreza Ebrahimiyan, Mohsen Basiri

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Drp1 is essential for PINK1/Parkin signaling in H9c2 cardiomyocytes by Xuecong Ren, Ni Zhang, Xiao‐Yi Chen, Hui Huang, Pei Luo

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THE EFFECT OF DECELLULARIZATION TECHNIQUE ON COLLAGEN TYPE II AND MATRICES POROSITY OF CARTILAGE BOVINE SCAFFOLD by Dwikora Novembri Utomo, Ika Benny Kartika Sari

“…Background: Cartilage has limited capacity for self-repair in case of defect. Stem cell based tissue engineering has become an alternative therapy for the treatment of cartilage defect. …”
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Intestinal organoids: The path towards clinical application by Hady Yuki Sugihara, Ryuichi Okamoto, Tomohiro Mizutani

“…In this review, we outline the current state of translational research involving adult stem cell and pluripotent stem cell derived intestinal organoids, highlighting the advances and limitations in disease modeling, drug-screening, personalized medicine, and stem cell therapy. …”
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Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency by Sílvia Bacalhau, Cristina Freitas, Rosalina Valente, Deolinda Barata, Conceição Neves, Katrin Schäfer, Annelie Lubatschofski, Ansgar Schulz, João Farela Neves

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Progenitor Hematopoietic Cells Implantation Improves Functional Capacity of End Stage Coronary Artery Disease Patients with Advanced Heart Failure by Yoga Yuniadi, Yuyus Kusnadi, Lakshmi Sandhow, Rendra Erika, Dicky A. Hanafy, Caroline Sardjono, R. W. M. Kaligis, Manoefris Kasim, Ganesja M. Harimurti

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Clinicopathologic Significance of HIF-1α, CXCR4, and VEGF Expression in Colon Cancer by Yugang Wu, Min Jin, Huanbai Xu, Zhang Shimin, Songbing He, Liang Wang, Yanyun Zhang

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Cerebral organoids: a promising model in cellular technologies by T. A. Shnaider

“…Finally, we regard existing problems and prospects for development of human pluripotent stem cell-derived threedimensional cerebral organoid technology.…”
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Pre-phase treatment with rituximab and high-dose methotrexate to re-evaluate eligibility for intensive induction treatment of frail patients with central nervous system lymphoma by Julia Wendler, Richard I. Lewis, Alexandra Kutilina, Markus Knott, Lisa Kristina Isbell, Elke Valk, Peter Borchmann, Jan-Michel Heger, Gerald Illerhaus, Elisabeth Schorb

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Drug delivery strategies to improve the treatment of corneal disorders by Mahsa Fallah Tafti, Zeinab Fayyaz, Hossein Aghamollaei, Khosrow Jadidi, Shahab Faghihi

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Mechanism of Repeat-Associated MicroRNAs in Fragile X Syndrome by Karen Kelley, Shin-Ju E. Chang, Shi-Lung Lin

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Regenerative Medicine for Neurological Disorders by Dong-Hyuk Park, David J. Eve, Yong-Gu Chung, Paul R. Sanberg

“…Newly developed stem cells, such as amniotic epithelial stem cells and induced pluripotent stem cells, as well as well-known traditional stem cells, such as neural, embryonic, bone marrow mesenchymal, and human umbilical cord blood–derived stem cells, were reported. …”
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Combined Rosiglitazone and Forskolin Have Neuroprotective Effects in SD Rats after Spinal Cord Injury by Qing-qi Meng, Wei Lei, Hao Chen, Zhen-cheng Feng, Li-qiong Hu, Xing-liang Zhang, Siming Li

“…The peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist rosiglitazone inhibits NF-κB expression and endogenous neural stem cell differentiation into neurons and reduces the inflammatory cascade after spinal cord injury (SCI). …”
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Effect of Vitronectin Bound to Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Protein-3 on Porcine Enamel Organ-Derived Epithelial Cells by Yoshinori Shinohara, Shuhei Tsuchiya, Kazuo Hatae, Masaki J. Honda

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New Evidence for <i>Cotinus coggygria</i> Scop. Extracts Application in Gastrointestinal Ailments by Dejan Stojković, Nina Dragičević, Marija Ivanov, Nevena Gajović, Milena Jurišević, Ivan Jovanović, Marina Tomović, Jelena Živković

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Telomere Length Is Associated With Adverse Atrial Remodeling in Patients With Atrial Fibrillation by Kabita Pradhan, Balram Neupane, Paul Niehues, Martin Kirschner, Fabian Beier, Chao‐Chung Kuo, Erika Anneliese Hilbold, Christian Bär, Oana‐Maria Thoma, Maximilian Waldner, Margherita Vieri, Tim H. Brümmendorf, Vithurithra Tharmapalan, Wolfgang Wagner, Michael Kleines, Mahdi Emrani, Matthias Daniel Zink, Andreas Napp, Nikolaus Marx, Michael Gramlich

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IL-12 and Related Cytokines: Function and Regulatory Implications in Candida albicans Infection by Robert B. Ashman, Dipti Vijayan, Christine A. Wells

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Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives by Osama A. Khairoalsindi, Ahmad R. Abuzinadah

“…The recent data on masitinib, the role of enteral feeding, gene therapy, and stem cell therapy is discussed.…”
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KMT2C/KMT2D-dependent H3K4me1 mediates changes in DNA replication timing and origin activity during a cell fate transition by Deniz Gökbuget, Liana Goehring, Ryan M. Boileau, Kayla Lenshoek, Tony T. Huang, Robert Blelloch

“…Using machine learning, we quantify 21 chromatin features predicting local RT and RT changes during differentiation in embryonic stem cells (ESCs). About one-third of the genome shows RT changes during differentiation. …”
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Frequency and Prognostic Relevance of FLT3 Mutations in Saudi Acute Myeloid Leukemia Patients by Ghaleb Elyamany, Mohammad Awad, Kamal Fadalla, Mohamed Albalawi, Mohammad Al Shahrani, Abdulaziz Al Abdulaaly

“…The Fms-like tyrosine kinase-3 (FLT3) is a receptor tyrosine kinase that plays a key role in cell survival, proliferation, and differentiation of hematopoietic stem cells. Mutations of FLT3 were first described in 1997 and account for the most frequent molecular mutations in acute myeloid leukemia (AML). …”
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