Effects of prophylactic antibiotic administration and antibiotic timing on culture results and clinical outcomes of paediatric musculoskeletal infection: a protocol for a randomise... by Chao You, Yibiao Zhou, Zhiyong Liu, Chao Deng, Yongjie Xia, Dechao Wu, Liangfu Xie, Bing E, Jingming Han

“…Using χ2 tests, the rates of positive cultures will be compared between different groups. Statistical comparisons between the different patient groups regarding the confounding and outcome variables will be conducted using independent t-tests, Mann-Whitney U tests, χ2 tests and Fisher’s exact tests as appropriate with the significance level set to 5% (p<0.05).Ethics and dissemination This study has received ethical approval. …”
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The Role of Heart Rate, Body Temperature, and Respiratory Rate in Predicting Anastomotic Leakage following Surgery for Rectal Cancer by Jiajun Luo, Hongxue Wu, Yue Jiang, Yu Yang, Jingwen Yuan, Qiang Tong

“…The differences in heart rate (1-5 d), body temperature (2-7 d), and respiratory rate (1-7 d) were statistically significant (P<0.05). The three ROC curves were drawn, respectively. …”
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Investigation of the Feasibility and Safety of a Highly Intensive Penetration Technique for Recanalization in Severe Calcified Femoropopliteal Occlusive Lesions: A Retrospective Ob... by Shinsuke Mori, Keisuke Hirano, Yusuke Setonaga, Toshihiko Kishida, Tomoya Fukagawa, Kohei Yamaguchi, Masafumi Mizusawa, Masakazu Tsutsumi, Norihiro Kobayashi, Yoshiaki Ito

“…Methods This single‐center, retrospective study enrolled 27 consecutive patients (29 limbs) who underwent the HIP technique for the recanalization of calcified femoropopliteal CTO lesions that were resistant to penetration by high‐tip load (≧ 40 g) guidewires between January 2015 and April 2023. Statistical analyses were performed using JMP 13 software. …”
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Ratio of Skeletal Muscle Mass to Visceral Fat Area Is a Useful Marker for Assessing Left Ventricular Diastolic Dysfunction among Koreans with Preserved Ejection Fraction: An Analys... by Jin Kyung Oh, Yuri Seo, Wonmook Hwang, Sami Lee, Yong-Hoon Yoon, Kyupil Kim, Hyun Woong Park, Jae-Hyung Roh, Jae-Hwan Lee, Minsu Kim

“…SVR showed a significant improvement in predictive performance and fair predictability for LVDD, with the highest area under the curve noted in both men and women, with statistical significance. In non-obese and metabolically healthy individuals, the lowest SVR tertile was associated with a greater risk of LVDD compared to the highest SVR tertile. …”
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e-GLR Score Predicts Early Graft Loss in Adult Live-Donor Liver Transplantation by Viniyendra Pamecha, MS, MRCS, FRCS, FEBS, Nilesh Sadashiv Patil, MS, MCh, Tharun Gattu, MS, Guresh Kumar, MSc, MPhil, PhD, Bramhadatta Pattnaik, MS, MCh, Nihar Mohapatra, MS, MCh, Gaurav Sindwani, MD, PDCC, Ashok Choudhury, MD, DM

“…Internal cross-validation revealed a high predictive value (C-statistic = 0.858). Conclusions:. Our novel risk score can efficiently predict early allograft loss following graft dysfunction, which enables donor-recipient matching, evaluation, and prognostication simply and reliably in adult LDLT.…”
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To Hemoadsorb or Not to Hemoadsorb—Do We Have the Answer Yet? An Updated Meta-Analysis on the Use of CytoSorb in Sepsis and Septic Shock by Carmen Orban, Angelica Bratu, Mihaela Agapie, Tudor Borjog, Mugurel Jafal, Romina-Marina Sima, Oana Clementina Dumitrașcu, Mihai Popescu

“…Ten studies containing 715 patients (355 in the interventional group and 360 in the control group) have been included in the final analysis. Results: Statistical analysis demonstrated that the use of CytoSorb did not influence overall mortality (OR 0.95, 95% CI [0.58, 1.56], <i>p</i> = 0.85), but we observed a decreased mortality when comparing CytoSorb-treated patients with patients in the control group treated with continuous renal replacement therapy (CRRT) (OR 0.97, 95% CI [0.46, 0.98], <i>p</i> = 0.04). …”
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Dyslipidemia Impacts Cardiometabolic Health and CVD Risk in a Relatively Young Otherwise Healthy Population by Jillian M. Lang, Elena S. Shostak, William K. Quinn, Valerie D. Chervinskaya, Elisa Fioraso, Everett Smith, Christopher J. Kotarsky, Justin A. DeBlauw, Jennifer L. Lloyd, Stephen J. Ives

“…Using a cross‐sectional approach, participants were characterized and grouped as having dyslipidemia or not, and then statistically assessed to determine whether differences in other cardiometabolic health measures existed between the groups. …”
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The Relationship between Carotid Intima-Media Thickness and Ocular Circulation in Type-2 Diabetes by Kohei Ichinohasama, Hiroshi Kunikata, Azusa Ito, Masayuki Yasuda, Shojiro Sawada, Keiichi Kondo, Chihiro Satake, Hideki Katagiri, Toru Nakazawa

“…In 129 subjects (129 eyes) with type-2 diabetes patients and mild NPDR or NDR, standard statistical techniques were used to determine associations between clinical findings, including diabetes duration, blood levels of creatinine and hemoglobin A1c (HbA1c), central macular thickness (CMT; measured with optical coherence tomography), mean blur rate (MBR; measured with laser speckle flowgraphy), and ultrasound-measured carotid IMT. …”
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Impact of Simulation-Based and Flipped Classroom Learning on Self-Perceived Clinical Skills Compared to Traditional Training by Samuel Agostino, Gian Maria Cherasco, Grazia Papotti, Alberto Milan, Federico Abate Daga, Massimiliano Abate Daga, Franco Veglio

“…All post-intervention improvements were statistically significant (<i>p</i> < 0.001). Conclusions: The combination of flipped classroom learning and intensive simulation training markedly improved students’ perceived clinical competence. …”
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Renal transplant recipient and deceased-donor risk profiles at Wits Donald Gordon Medical Centre, Johannesburg, South Africa: A 9-year review by F van der Schyff, M Barnard, B Ströbele, M de Jager, R Britz, P Gaylard, J Loveland

“…Both these scores performed poorly in predicting graft and patient survival, with a C-statistic of 0.5. Renal recipient risk scores also demonstrated low- to average-risk patients being transplanted, with a median Hennepin score of 2 - 4 points and a KTMI of 2 points. …”
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EMA/CO Combination Chemotheraphy in Gestational Trophoblastic Neoplasia: Update of Our Results by Tolga Taşçı, Işın Üreyen, Günsu Kimyon, Alper Karalök, Sevgi Koç, M. Faruk Köse, Gökhan Tulunay, Taner Turan

“…The effects of tumor dimension and the presence of metastasis tended to be statistically significant in determining the resistance to therapy. …”
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Optimizing water-use efficiency under elevated CO₂: A meta-analysis of crop type, soil modulation, and enrichment methods by Ali Mokhtar, Hongming He, Samar Attaher, Ali Salem, Muneer Alam

“…Therefore, in this study, we have conducted a meta-analysis to quantitative statistical means among studies and discuss how WUE responds to eCO2 under pathway (C3 and C4), four enrichment methods and soil types based on 124 peer-reviewed studies and 1474 observations to provide an in-depth overview of how these factors interact under future CO₂ scenarios. …”
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Eye movement desensitisation and reprocessing for childbirth-related post-traumatic stress symptoms: effectiveness, duration and completion by A. Doherty, U. Nagle, J. Doyle, R. M. Duffy, R. M. Duffy

“…Limitations include lack of a control group and long-term follow-up, and statistical analyses were limited by sample size.…”
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Digital Device Use, Computer Vision Syndrome, and Sleep Quality among an African Undergraduate Population by Prince Kwaku Akowuah, Augustine N. Nti, Stephen Ankamah-Lomotey, Asafo Agyei Frimpong, Jeremiah Fummey, Prince Boadi, Kofi Osei-Poku, Joseph Adjei-Anang

“…Logistic regression was used to determine the relationship between CVS and digital device use behavior, and linear regression analysis was used to explore the association between sleep quality and digital device use behavior. Statistical significance was set at p < 0.05. Results. …”
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A microstructure-based numerical approach for uniaxial fatigue life-based non-uniaxial fatigue life prediction of hypo-eutectoid steels by Jonghoon Shin, Hyunki Kim, Minwoo Kang, Chungan Lee, Seunghyun Hong, Yoon Suk Choi

“…The proposed prediction procedure involves the generation of a statistically representative synthetic microstructure, the development of slip system-based fatigue constitutive models for the primary ferrite and pearlite phases constituting the hypo-eutectoid steel, the synthetic microstructure-based finite element simulations for uniaxial, torsional, and in-phase and out-of-phase axial plus torsional fatigue loading conditions using the developed constitutive models, the extraction of the cyclic increment of the fatigue indicator parameters (ΔFIP) from fatigue-simulated microstructures for the local fatigue damage quantification, the calibration of the uniaxial fatigue life prediction model by linking simulated uniaxial ΔFIPs to the uniaxial fatigue life data, and finally the prediction of the non-uniaxial fatigue life (through simulated non-uniaxial ΔFIPs) using the uniaxial fatigue-calibrated life prediction model. …”
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Is There a Relationship between the Staining Pattern of Classical Neuroendocrine Markers and Clinicopathological Findings in Neuroendocrine Tumors of the Appendix? by Merve CİN, Enver YARIKKAYA, Selçuk CİN, Özgecan GÜNDOĞAR

“…Histomorphological patterns included small nests, large nests, and trabecular-palisading patterns. Statistically significant correlations were observed between Snp staining intensity and tumor size, and Chr staining extensity and histomorphologic patterns. …”
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Biomarker microRNA-371a-3p - expression in malignancies other than germ-cell tumours by Gazanfer Belge, Markus Klemke, Bendix Hansen, Cansu Dumlupinar, Aylin Igde, Dirk Arnold, Hans Salwender, Christian Wülfing, Armin Soave, Klaus-Peter Dieckmann

“…The results were compared with GCT patients (n = 20) and with tumour-free male controls (n = 20) using descriptive statistical methods. Results Eight patients with NTMs had M371 serum level elevations, corresponding to a false-positive rate (FPR) of 5.84% (95% confidence intervals (CIs) 2.55–11.18%). …”
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Effect of age on the treatment duration and proposed “impacted incisor severity score” of impacted maxillary incisor: A retrospective study by Umer Mukhtar, Manoj kumar Jaiswal, Rigzen Tamchos, Ashima Goyal, Satinder Pal Singh, Aditi Kapur

“…The mean duration of treatment time was found to be 16.77 ± 8.83months and 21.75 ± 6.08months for impacted incisors with normal morphology and with dilaceration, respectively and the difference was statistically significant (p = 0.042). Conclusions: Considering the age of the patient, it does not show significant effect on the duration of treatment, but a change in root morphology like dilaceration, significantly increases the duration of treatment. …”
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Role of apoptosis genes in aggression revealed using combined analysis of ANDSystem gene networks, expression and genomic data in grey rats with aggressive behavior by A. O. Bragin, O. V. Saik, I. V. Chadaeva, P. S. Demenkov, A. L. Markel, Yu. L. Orlov, E. I.  Rogaev, I. N. Lavrik, V. A. Ivanisenko

“…It was shown that polymorphic and differentially expressed genes were statistically significantly overrepresented among ge nes interacting with neuronal apoptosis genes (p value &lt; 0.01). …”
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Association of walking cadence to changes in knee pain and physical function: The multicenter osteoarthritis study by Khara A. James, Tuhina Neogi, David T. Felson, Patrick Corrigan, Cara L. Lewis, Irene S. Davis, Kathryn L. Bacon, James C. Torner, Cora E. Lewis, Michael C. Nevitt, Joshua J. Stefanik

“…For every 10-step/min decrease in cadence, the risk of incident knee symptoms increased by 10 ​% (RR ​= ​1.10, 95%CI [0.97, 1.25]), though this was not statistically significant and was attenuated after adjusting for gait speed (RR ​= ​0.95, 95%CI [0.80, 1.12]). …”
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