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High Ki67 expression, HER2 overexpression, and low progesterone receptor levels in high-grade DCIS: significant associations with clinical practice implications
Published 2025-01-01“…Additionally, we investigated the associations between Ki67 expression, PR levels, and human epidermal growth factor receptor 2 (HER2) in high-grade DCIS among various subtypes (Luminal (Lum) A, LumB HER2-, LumB HER2+, HER2-enriched, and triple-negative)).MethodsUsing histopathological specimens from 484 patients diagnosed with DCIS between 1996 and 2018, we implemented the 2013 St. Gallen recommendations for surrogate immunomolecular subtyping of IBC. …”
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Preventing sensory and motor dysfunctions in children receiving neurotoxic chemotherapy: PrepAir study - an update
Published 2025-01-01“…Methods We are thefore currently running a large, prospective, multicenter, randomized and controlled study in six hospital centers (Basel, Bern, Aarau, St. Gallen, Freiburg (D), Berlin (D)). N=131 children between 6-18 years, undergoing neurotoxic chemotherapy, will be assigned to an intervention group or a treatment-as-usual group. …”
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