An Indole Alkaloid Extracted from Evodia rutaecarpa Inhibits Colonic Motility of Rats In Vitro by Guo-xiang Wang, Yan-li Xiang, Hong-gang Wang, Yang-de Miu, Guang Yu

“…Whole-cell patch-clamp was used to detect L-type calcium currents (ICa,L) in isolated colonic smooth muscle cells (SMCs). CCK1R was observed in SMCs, intermuscular neurons, and mucosa of rat colon. …”
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Glomus Tumor of the Stomach: A Rare Cause of Upper Gastrointestinal Bleeding by Enzo Fabrício Ribeiro Nascimento, Fábio Piovezan Fonte, Roberta Laís Mendonça, Ronaldo Nonose, Carlos Alberto Fonte de Souza, Carlos Augusto Real Martinez

“…The pathological exam revealed hyperplastic smooth muscle fibers of the muscularis propria of the stomach wall, surrounded by hyaline stroma. …”
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Downregulation of Thromboxane A2 Receptor Occurs Mainly via Nuclear Factor-KappaB Signaling Pathway in Rat Renal Artery by Yaping Zhang, Man Mi, Yan-Hua Xie, Si-Wang Wang, Lars Edvinsson, Cang-Bao Xu

“…In conclusion, downregulation of TP receptors in the renal artery smooth muscle cells occurs mainly via the NF-κB signaling pathway.…”
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Vascular Contractility Relies on Integrity of Progranulin Pathway: Insights Into Mitochondrial Function by Shubhnita Singh, Ariane Bruder, Rafael M. Costa, Juliano V. Alves, Sivakama Bharathi, Eric S. Goetzman, Thiago Bruder‐Nascimento

“…In addition, in vivo treatment with mitochondrial fission inhibitor restored mitochondrial quality and vascular contractility, while vascular smooth muscle cells overexpressing PGRN displayed higher lysosome biogenesis, accelerated mitophagy flux, and mitochondrial respiration accompanied by vascular hypercontractility. …”
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Discovery of Novel Caeridins from the Skin Secretion of the Australian White’s Tree Frog, Litoria caerulea by Lei Li, Qing Wu, Xi Wang, Huimin Lu, Xinping Xi, Mei Zhou, Chris J. Watson, Tianbao Chen, Lei Wang

“…Chemically synthetic versions of each natural Caeridin demonstrated promising bioactivities either on rat smooth muscles or against microbial growth. Specifically, Caeridin-1 produced contraction of rat bladder smooth muscle, while S5-Caeridin-1 induced relaxation of rat ileum smooth muscle, both at nanomolar concentrations. …”
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Ghrelin Protects Lipopolysaccharide-Induced Acute Lung Injury Rats against Pulmonary Vascular Dysfunction by Inhibiting Inflammation by Guang Li, Chen-Liang Zhou, Wen-Fang Xia, Di Zhang, Hui-Qing Lin

“…Immunohistochemical staining to detect alpha-smooth muscle actin (α-SMA) and proliferating cell nuclear antigen (PCNA) expression was performed to assess the intrapulmonary arterial wall thickness and the proliferation of smooth muscle cells, respectively. …”
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Recurrent Midgut Bleeding due to Jejunal Angioleiomyoma by Mahir Gachabayov, Petr Mityushin

“…Angioleiomyoma being a type of true smooth muscle gastrointestinal tumors can lead to serious life-threatening gastrointestinal bleeding. …”
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Leiomyoma of the Renal Vein: A Rare Tumor Presenting as a Renal Mass by Cengiz Kocak, Sahin Kabay, Burak Isler

“…They are less commonly found in the muscularis propria of the renal pelvis and cortical vascular smooth muscle. In this case report, we present a 41-year-old woman who had right flank pain and detected a mass in the right kidney hilum.…”
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Multiple Extrauterine Adenomyomas Presenting in Upper Abdomen and Pelvis: A Case Report and Brief Review of the Literature by Mana Moghadamfalahi, Daniel S. Metzinger

“…Adenomyomas are benign tumors composed of smooth muscle and endometrial tissue. These tumors usually arise from the myometrium. …”
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A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature by Yasushi Ariizumi, Hirotaka Koizumi, Masahiro Hoshikawa, Takuo Shinmyo, Kouji Ando, Atsushi Mochizuki, Ayako Tateishi, Masatomo Doi, Mieko Funatsu, Ichirou Maeda, Masayuki Takagi

“…Electron microscopy revealed smooth muscle differentiation of the tumor cells. Immunostaining further revealed that the tumor cells expressed smooth muscle actin, h-caldesmon, muscle specific actin (HHF-35), but not cytokeratin, epithelial membrane antigen, synaptophysin, or chromogranin A. …”
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Acroparesthesia in a Female: Diagnostic Dilemma by Fnu Kelash, Lara Kujtan, Padmaja V. Mallidi

“…The disease affects nearly all major organ systems, with the primary sites damaged by Gb3 including renal glomeruli, myocardium, neurons of the dorsal ganglion and autonomic nervous system, and vascular endothelial and smooth muscle. Progressive deposition in these organ systems leads to renal and heart failure; debilitating pain as a result of nervous system involvement also occurs.…”
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Unusual Presentation of Leiomyoma in the Hindfoot by Abdullah Zaher, Jaouad Yasser, Daniel Badaro, Noureddine Sekkach

“…A leiomyoma is a benign smooth muscle tumor that is most commonly found in the uterus. …”
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Receptor mechanisms of PAF mediated lymphatic constriction in the canine forelimb by D. E. Dobbins

“…These data indicate that in addition to PAF's effects on microvascular permeability, this agent may also impact the ability of the lymphatics to transport fluid through alterations in lymphatic smooth muscle tone. PAF mediated lymphatic constriction is not mediated by α-receptors but rather through PAF receptor mediated mechanism.…”
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Clinical Practice Guidelines for Severe Asthma Treatment. by Eddy Pereira Valdes, Moisés Santos Peña, Belkys Rodríguez Llerena

“…This disease is characterized by an overreaction of the tracheobronchial tree with hyperactivity after certain stimulus consisting of a diffuse narrowing of the respiratory ways related with an excessive contraction of the bronchial smooth muscle, hyper-secretion of mucus and mucosa edema. …”
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A novel case of left atrial and right lung mass turned out to be unconventional metastasis of uterine leiomyosarcoma with a review of literature by Tarang Patel, Priyanka Aswal, Ashish Jakhetiya, Virendrakumar Meena, Arun Pandey

“…Uterine leiomyosarcoma (ULMS) is a rare malignancy arising from the myometrial smooth muscle wall, and cardiac metastases are extremely rare. …”
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Coexisting Angiomyolipoma and Renal Cell Carcinoma in a Kidney of an Elderly Woman: Case Report and Review of the Literature by Barry Billings, Leon C. Hamrick, Anton J. Bueschen, Philip J. Kenney

“…Angiomyolipoma is a well described but relatively uncommon benign renal neoplasm composed of varying admixtures of mature adipose tissue, smooth muscle, and thick-walled blood vessels.[1] The incidence of angiomyolipoma is about 0.3% overall.[2] It frequently occurs in patients with tuberous sclerosis. …”
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Investigation of the effects of vitamin D and calcium on intestinal motility: In vitro tests and implications for clinical treatment by Giraldi Guglielmo, Fioravanti Angelo, De Luca d’Alessandro Eugenia, Palmery Maura, Martinoli Lucia

“…The presence of vitamin D receptors in small intestine muscle cells may lead one to think that vitamin D may act locally, influencing intracellular calcium concentration and contributing to the contraction-relaxation regulation of the intestinal smooth muscle cells. This study investigates the potential effects of vitamin D and calcium on intestinal motility using an in vitro test.…”
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Beneficial Effects of Prebiotic Saccharomyces cerevisiae Mannan on Allergic Asthma Mouse Models by D. Betty Lew, Christie F. Michael, Tracie Overbeck, W. Scout Robinson, Erin L. Rohman, Jeffrey M. Lehman, Jennifer K. Patel, Brandi Eiseman, Kim S. LeMessurier, Amali E. Samarasinghe, M. Waleed Gaber

“…One of the unmet needs for asthma management is a new therapeutic agent with both anti-inflammatory and anti-smooth muscle (ASM) remodeling effects. The mannose receptor (MR) family plays an important role in allergen uptake and processing of major allergens Der p 1 and Fel d 1. …”
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Determinants of Vessel Targeting in Vasculitis by Gary S. Hoffman

“…Studies of vascular diseases must assess how such variables may affect regional differences in endothelial cells, subendothelial matrix, vascular smooth muscle and the response of each to a variety of stimuli.…”
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Paraurethral Leiomyoma in a Postmenopausal Woman: First European Case by Susy Shim, Camilla Skovvang Borg, Huda Galib Majeed, Peter Humaidan

“…Leiomyomas are benign tumors extending from smooth muscle cells and only few cases of paraurethral leiomyomas have been described in the literature. …”
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