Regulation and Roles of Urocortins in the Vascular System by Kazunori Kageyama, Ken Teui, Naoki Tamasawa, Toshihiro Suda

“…Ucn1 and Ucn2 have strong effects on interleukin (IL)-6 gene expression and secretion in rat aortic smooth muscle A7r5 cells. The increase that we observed in IL-6 levels following Ucn treatment of A7r5 cells suggests that smooth muscle cells may be a source of IL-6 secretion under physiological stress conditions. …”
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Nitric Oxide - Its Importance in Swallowing, Inflammatory Bowel Disease and Cirrhotic Cardiomyopathy by ABR Thomson

“…The neurosubstances mediating striated and smooth muscle peristalsis may be both anatomically and neurochemically distinct. …”
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Cardiovascular Disease in Ageing: An Overview on Thoracic Aortic Aneurysm as an Emerging Inflammatory Disease by Calogera Pisano, Carmela Rita Balistreri, Alessandro Ricasoli, Giovanni Ruvolo

“…Medial degeneration associated with thoracic aortic aneurysm and acute aortic dissection was originally described by Erdheim as a noninflammatory lesion related to the loss of smooth muscle cells and elastic fibre fragmentation in the media. …”
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Cell-Specific Dual Role of Caveolin-1 in Pulmonary Hypertension by Rajamma Mathew

“…Caveolin-1, a membrane scaffolding protein found in a number of cells including endothelial and smooth muscle cells, has been implicated in PH. Loss of endothelial caveolin-1 is reported in clinical and experimental forms of PH. …”
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Ranakinestatin-PPF from the Skin Secretion of the Fukien Gold-Striped Pond Frog, Pelophylax plancyi fukienensis: A Prototype of a Novel Class of Bradykinin B2 Receptor Antagonist P... by Jie Ma, Yu Luo, Lilin Ge, Lei Wang, Mei Zhou, Yingqi Zhang, Jinao Duan, Tianbao Chen, Chris Shaw

“…Members of this peptide group are also common components of reptile and arthropod venoms due to their multiple biological functions that include induction of pain, effects on many smooth muscle types, and lowering systemic blood pressure. …”
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Lipoleiomyoma of the uterus in a woman of reproductive age (clinical case) by V.V. Talash, Ya.V. Palyokha, A.M. Gromova, V.V. Talash, V.B. Martynenko, N.O. Prylutska, N.I. Mityunina

“…Microscopically, the lipoleiomyoma had a mesenchymal structure with a pronounced vascular component and consisted of mitotically inactive bundles of smooth muscle cells and mature adipocytes. Im­munohistochemically, a positive reaction for caldesmon, desmin, smooth muscle actin alpha of tumor cells and for S.100 (DAKO, polyclonal) fatty cells was detected, which confirmed the hypothesis of direct transformation of smooth muscle cells existing in the leiomyoma of the uterus into fatty cells. …”
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LOX-1, OxLDL, and Atherosclerosis by Angela Pirillo, Giuseppe Danilo Norata, Alberico Luigi Catapano

“…Oxidized low-density lipoprotein (OxLDL) contributes to the atherosclerotic plaque formation and progression by several mechanisms, including the induction of endothelial cell activation and dysfunction, macrophage foam cell formation, and smooth muscle cell migration and proliferation. Vascular wall cells express on their surface several scavenger receptors that mediate the cellular effects of OxLDL. …”
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Effect of Caloric Restriction on Hepatic Sinusoidal System and Stellate Cells in Mice by Jian Chen, Kara King, Jian X. Zhang

“…However, caloric restriction had no impact on stellate cell activity level as indicated by the unaffected α-smooth muscle actin expression.…”
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Attenuation of Autoimmune Phenomena in a Patient with Autoimmune Polyglandular Syndrome Type 1 by Jill D. Jacobson, Julia R. Broussard, Courtney Marsh, Brandon Newell

“…Serologic testing revealed antibodies to 21-hydroxylase, intrinsic factor, and smooth muscle. Hydrocortisone was initiated for adrenal insufficiency. …”
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Three-dimensional ultrastructural analysis of human skin with the arrector pili muscle interacting with the hair follicle epithelium by Tomonobu Ezure, Kyoichi Matsuzaki, Hidetoshi Urakubo, Nobuhiko Ohno

“…Additionally, the dense nerve network running through and along arrector pili muscle fibers rarely penetrates the connective tissues between smooth muscle fibers and epithelial cells. Furthermore, in the observation area, no individual smooth muscle fibers formed adhesion structures with the epithelial cells of the hair follicle, ending in the dermal extracellular matrix near the epithelial cells. …”
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The Impact of Levothyroxine and Testosterone Administration on Bladder Contractility in the Rat Model of Propylthiouracil-Induced Hypothyroidism by Didem Yılmaz Oral, Berna Güven Ciloğlu, Serap Gür

“…In males with hypothyroidism and urogenital system dysfunction, combination therapy with thyroid hormones and T has a major impact on repairing detrusor smooth muscle contractility and bladder histomorphology.…”
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HISTOMORPHOLOGICAL ENHANCEMENT OF THE VAGINAL WALL IN DEHYDROEPIANDROSTERONE-TREATED POST-OVARIECTOMIZED WISTAR RATS by Lis Widodo Peni, Pilar Menara Falah, Yudha Nurdian

“…Result: The mean of epithelial and smooth muscle thickness of the treatment group was significantly higher than that of the control group (p-value < 0.05). …”
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Mitochondrial apoptosis in response to cardiac ischemia-reperfusion injury by Kaixin Wang, Qing Zhu, Wen Liu, Linyuan Wang, Xinxin Li, Cuiting Zhao, Nan Wu, Chunyan Ma

“…The death of each cell (cardiomyocytes, endothelial cells, vascular smooth muscle cells, cardiac fibroblasts, and mesenchymal stem cells) after myocardial ischemia/reperfusion is associated with apoptosis due to mitochondrial dysfunction. …”
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Notch Regulation of Hematopoiesis, Endothelial Precursor Cells, and Blood Vessel Formation: Orchestrating the Vasculature by Vincenza Caolo, Daniel G. M. Molin, Mark J. Post

“…Recruitment towards the endothelial tubes and subsequent differentiation of pericyte and/or vascular smooth muscle cells (vSMCs) takes place and the mature vessel is formed. …”
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Lipoleiomyoma of the Uterus and Primary Ovarian Leiomyoma in a Postmenopausal Woman: Two Rare Entities in the Same Individual by Sefa Kelekci, Serenat Eris, Emine Demirel, Serpil Aydogmus, Nese Ekinci

“…Uterine lipoleiomyomas are rare benign tumours that are composed of various mixtures of smooth muscle and mature fat tissue. Leiomyomas, which arise primarily in the ovary, are extremely rare tumours that account for 0.5–1% of all benign ovarian tumours. …”
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LncRNA MDRL Mitigates Atherosclerosis through miR-361/SQSTM1/NLRP3 Signaling by Ling You, Yanjie Zheng, Jing Yang, Qian Hou, Lianxia Wang, Yan Zhang, Chunxia Zhao, Ruiqin Xie

“…Here, we sought to determine that mitochondrial dynamic related lncRNA (MDRL) modulates NLRP3 inflammasome activation and apoptosis of vascular smooth muscle cells (VSMCs) and protects arteries against atherosclerosis. …”
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Bronchial responses to substance P after antigen challenge in the guinea-pig: in vivo and in vitro studies by E. Boichot, V. Lagente, G. Le Gall, C. Carré, J. M. Mencia-Huerta, P. Braquet, A. Lockhart, N. Frossard

“…However, in vitro, the contractile responses of the tracheal smooth muscle to substance P were similar between groups of guinea-pigs, in respect to the presence or absence of the epithelium and/or phosphoramidon. …”
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Caffeine's Vascular Mechanisms of Action by Darío Echeverri, Félix R. Montes, Mariana Cabrera, Angélica Galán, Angélica Prieto

“…Nitric oxide is diffused to the vascular smooth muscle cell to produce vasodilation. In vascular smooth muscle cells its effect is predominantly a competitive inhibition of phosphodiesterase, producing an accumulation of cAMP and vasodilation. …”
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Intravascular Leiomyomatosis as a Rare Cause of Nonthrombotic Pulmonary Embolism by Julie Van Maercke, Anne-Sophie Van Rompuy, Willy Poppe, Tom Verbelen, Marion Delcroix, Catharina Belge

“…It is characterized by the proliferation of benign smooth muscle cells within vascular structures without invasion of these tissues. …”
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Androgen Effects on the Adrenergic System of the Vascular, Airway, and Cardiac Myocytes and Their Relevance in Pathological Processes by Abril Carbajal-García, Jorge Reyes-García, Luis M. Montaño

“…Catecholamines play a crucial role in regulating vascular smooth muscle (VSM), airway smooth muscle (ASM), and cardiac muscle (CM) function and tone. …”
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