Showing 21 - 40 results of 51 for search '"Signal Transduction and Targeted Therapy"', query time: 0.06s Refine Results
  1. 21
    Emerging regulatory mechanisms and functions of biomolecular condensates: implications for therapeutic targets

    Emerging regulatory mechanisms and functions of biomolecular condensates: implications for therapeutic targets by Soyoung Jeon, Yeram Jeon, Ji-Youn Lim, Yujeong Kim, Boksik Cha, Wantae Kim

    Published 2025-01-01
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  2. 22
    Safety and efficacy of trifluridine/tipiracil +/− bevacizumab plus XB2001 (anti-IL-1α antibody): a single-center phase 1 trial

    Safety and efficacy of trifluridine/tipiracil +/− bevacizumab plus XB2001 (anti-IL-1α antibody): a single-center phase 1 trial by Marion Thibaudin, Nicolas Roussot, Chloé Burlot, Antonin Schmitt, Julie Vincent, Zoé Tharin, Leila Bengrine, Hélène Bellio, Aurélie Bertaut, Léa Hampe, Susy Daumoine, Emilie Rederstorff, Morgane Peroz, Titouan Huppe, Valentin Derangère, David Rageot, John Simard, Caroline Truntzer, Jean David Fumet, Francois Ghiringhelli

    Published 2025-01-01
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  3. 23
    Roles of human papillomavirus in cancers: oncogenic mechanisms and clinical use

    Roles of human papillomavirus in cancers: oncogenic mechanisms and clinical use by Yu Zhang, Ke Qiu, Jianjun Ren, Yu Zhao, Ping Cheng

    Published 2025-01-01
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  4. 24
    Malate initiates a proton-sensing pathway essential for pH regulation of inflammation

    Malate initiates a proton-sensing pathway essential for pH regulation of inflammation by Yu-jia-nan Chen, Rong-chen Shi, Yuan-cai Xiang, Li Fan, Hong Tang, Gang He, Mei Zhou, Xin-zhe Feng, Jin-dong Tan, Pan Huang, Xiao Ye, Kun Zhao, Wen-yu Fu, Liu-li Li, Xu-ting Bian, Huan Chen, Feng Wang, Teng Wang, Chen-ke Zhang, Bing-hua Zhou, Wan Chen, Tao-tao Liang, Jing-tong Lv, Xia Kang, You-xing Shi, Ellen Kim, Yin-hua Qin, Aubryanna Hettinghouse, Kai-di Wang, Xiang-li Zhao, Ming-yu Yang, Yu-zhen Tang, Hai-long Piao, Lin Guo, Chuan-ju Liu, Hong-ming Miao, Kang-lai Tang

    Published 2024-12-01
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  5. 25
    Perioperative tislelizumab plus chemotherapy for locally advanced gastroesophageal junction adenocarcinoma (NEOSUMMIT-03): a prospective, nonrandomized, open-label, phase 2 trial

    Perioperative tislelizumab plus chemotherapy for locally advanced gastroesophageal junction adenocarcinoma (NEOSUMMIT-03): a prospective, nonrandomized, open-label, phase 2 trial by Run-Cong Nie, Shu-Qiang Yuan, Ya Ding, Yong-Ming Chen, Yuan-Fang Li, Cheng-Cai Liang, Mu-Yan Cai, Guo-Ming Chen, Wei Wang, Xiao-Wei Sun, De-Sheng Weng, Dan-Dan Li, Jing-Jing Zhao, Xiao-Jiang Chen, Yuan-Xiang Guan, Zhi-Min Liu, Yao Liang, Ma Luo, Jun Chi, Hai-Bo Qiu, Zhi-Wei Zhou, Xiao-Shi Zhang, Ying-Bo Chen

    Published 2025-02-01
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  6. 26
    CD4 T cell contact drives macrophage cell cycle G0-G1 transition

    CD4 T cell contact drives macrophage cell cycle G0-G1 transition by Petra Mlcochova, Na Zhao, Omar Shabana, Roman Fischer, Ravindra K. Gupta

    Published 2024-12-01
    “…Signal Transduction and Targeted Therapy…”
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  7. 27
    Proteins lead the way: JAK inhibitors as a new treatment option in toxic epidermal necrolysis

    Proteins lead the way: JAK inhibitors as a new treatment option in toxic epidermal necrolysis by Benjamin Klein, J. Michelle Kahlenberg, Johann E. Gudjonsson

    Published 2025-02-01
    “…Signal Transduction and Targeted Therapy…”
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  8. 28
    Mucosal immune response in biology, disease prevention and treatment

    Mucosal immune response in biology, disease prevention and treatment by Xiaoxue Zhou, Yuchen Wu, Zhipeng Zhu, Chu Lu, Chunwu Zhang, Linghui Zeng, Feng Xie, Long Zhang, Fangfang Zhou

    Published 2025-01-01
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  9. 29
    Immunotherapy in ovarian cancer: spatial functional genomics to unravel resistance mechanisms

    Immunotherapy in ovarian cancer: spatial functional genomics to unravel resistance mechanisms by Martina Rausch, Karlotta Bartels, Josef Leibold

    Published 2025-01-01
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  10. 30
    Neoadjuvant pyrotinib and trastuzumab in HER2-positive breast cancer with no early response (NeoPaTHer): efficacy, safety and biomarker analysis of a prospective, multicentre, response-adapted study

    Neoadjuvant pyrotinib and trastuzumab in HER2-positive breast cancer with no early response (NeoPaTHer): efficacy, safety and biomarker analysis of a prospective, multicentre, resp... by Fei Wang, Yongjiu Wang, Bin Xiong, Zhenlin Yang, Jingfen Wang, Yumin Yao, Lixiang Yu, Qinye Fu, Liang Li, Qiang Zhang, Chao Zheng, Shuya Huang, Liyuan Liu, Chun Liu, Huaibo Sun, Beibei Mao, Dong-Xu Liu, Zhigang Yu

    Published 2025-01-01
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  11. 31
    Digestive cancers: mechanisms, therapeutics and management

    Digestive cancers: mechanisms, therapeutics and management by Tianzuo Zhan, Johannes Betge, Nadine Schulte, Lena Dreikhausen, Michael Hirth, Moying Li, Philip Weidner, Antonia Leipertz, Andreas Teufel, Matthias P. Ebert

    Published 2025-01-01
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  12. 32
    A multicenter, randomized, double-blind, placebo-controlled phase 3 study of Socazolimab or placebo combined with carboplatin and etoposide in the first-line treatment of extensive-stage small cell lung cancer

    A multicenter, randomized, double-blind, placebo-controlled phase 3 study of Socazolimab or placebo combined with carboplatin and etoposide in the first-line treatment of extensive... by Zhiwei Chen, Jianhua Chen, Dingzhi Huang, Wei Zhang, Lin Wu, Tienan Yi, Qiming Wang, Liang Han, Liping Tan, Yinyin Li, Zhihong Zhang, Na Li, Jie li, Tongmei Zhang, Ying Hu, Hongmei Sun, Youhua Wu, Zhiyong He, Runxiang Yang, Peng Cheng, Xingya Li, Jianhua Shi, Guohua Yu, Daiyuan Ma, Benjamin Xiaoyi Li, Xiangrong Dai, Michael Wong, Yujie Li, Xiaohui Yu, Shun Lu, for the Socazolimab Study Group

    Published 2025-01-01
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  13. 33
    Beyond incretins: targeting neurokinin receptors for obesity treatment

    Beyond incretins: targeting neurokinin receptors for obesity treatment by Doreen Thor, Simone Prömel

    Published 2025-01-01
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  14. 34
    Dual targeting PD-L1 and 4-1BB to overcome dendritic cell-mediated lenalidomide resistance in follicular lymphoma

    Dual targeting PD-L1 and 4-1BB to overcome dendritic cell-mediated lenalidomide resistance in follicular lymphoma by Zhong Zheng, Jian-Biao Wang, Rui Sun, Nan Wang, Xiang-Qin Weng, Tian-Yuan Xu, Di Fu, Yan Feng, Peng-Peng Xu, Shu Cheng, Li Wang, Yan Zhao, Bin Qu, Chuan-Xin Huang, Wei-Li Zhao

    Published 2025-01-01
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  15. 35
    Single-cell transcriptomics reveals novel chondrocyte and osteoblast subtypes and their role in knee osteoarthritis pathogenesis

    Single-cell transcriptomics reveals novel chondrocyte and osteoblast subtypes and their role in knee osteoarthritis pathogenesis by Yuan Liu, Wacili Da, Ming-Jie Xu, Chao-Xin Xiao, Tao Deng, Sheng-Liang Zhou, Xiao-Ting Chen, Yao-Jia Zhou, Li Tang, Yong Nie, Yi Zeng, Hui-Qi Xie, Bin Shen

    Published 2025-02-01
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  16. 36
    Molecular mechanisms in liver repair and regeneration: from physiology to therapeutics

    Molecular mechanisms in liver repair and regeneration: from physiology to therapeutics by Xiao Ma, Tengda Huang, Xiangzheng Chen, Qian Li, Mingheng Liao, Li Fu, Jiwei Huang, Kefei Yuan, Zhen Wang, Yong Zeng

    Published 2025-02-01
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  17. 37
    Artesunate: attenuating TLR4/MD2 signaling to alleviate cardiac fibrosis

    Artesunate: attenuating TLR4/MD2 signaling to alleviate cardiac fibrosis by Lars Koch, Konrad Hoeft, Rafael Kramann

    Published 2025-01-01
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  18. 38
    A pan-immune panorama of bacterial pneumonia revealed by a large-scale single-cell transcriptome atlas

    A pan-immune panorama of bacterial pneumonia revealed by a large-scale single-cell transcriptome atlas by Kun Xiao, Yan Cao, Zhihai Han, Yuxiang Zhang, Laurence Don Wai Luu, Liang Chen, Peng Yan, Wei Chen, Jiaxing Wang, Ying Liang, Xin Shi, Xiuli Wang, Fan Wang, Ye Hu, Zhengjun Wen, Yong Chen, Yuwei Yang, Haotian Yu, Lixin Xie, Yi Wang

    Published 2025-01-01
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  19. 39
    Protecting cell cycle integrity: enhanced start-codon stringency in mitosis

    Protecting cell cycle integrity: enhanced start-codon stringency in mitosis by Omid Omrani, Kanstantsin Siniuk, Martin Fischer

    Published 2025-02-01
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  20. 40
    Cancer cell reprogramming: turning the enemy into an ally

    Cancer cell reprogramming: turning the enemy into an ally by Severin Guetter, Kaiji Fan, Hendrik Poeck

    Published 2025-01-01
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