Influence of the Clinical Status on Stress Reticulocytes, CD 36 and CD 49d of SSFA2 Homozygous Sickle Cell Patients Followed in Abidjan by Duni Sawadogo, Aïssata Tolo-Dilkébié, Mahawa Sangaré, Nelly Aguéhoundé, Hermance Kassi, Toussaint Latte

“…The expression of adhesion molecules is only one of the parameters involved in sickle cell disease crisis.…”
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Medical Resource Use and Costs of Treating Sickle Cell-related Vaso-occlusive Crisis Episodes: A Retrospective Claims Study by Nirmish Shah, Menaka Bhor, Lin Xie, Jincy Paulose, Huseyin Yuce

“…**Background:** The study investigated the economic burden of vaso-occlusive crisis (VOC) among sickle cell disease (SCD) patients, through assessment of overall utilization and costs and costs per VOC episode (regarding the number of VOC episodes and health care setting, respectively). …”
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Foetal Haemoglobin, Erythrocytes Containing Foetal Haemoglobin, and Hematological Features in Congolese Patients with Sickle Cell Anaemia by L. Tshilolo, V. Summa, C. Gregorj, C. Kinsiama, J. A. Bazeboso, G. Avvisati, D. Labie

“…High HbF levels and F cells are correlated with reduced morbidity and mortality in sickle cell disease (SCD). This paper was designed to determine the HbF and F cells levels in Congolese sickle cell anemia (SCA) patients in order to determine their impact on the expression of SCD. …”
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Limited Exchange Transfusion Can Be Very Beneficial in Sickle Cell Anemia with Acute Chest Syndrome: A Case Report from Tanzania by Clara Chamba, Hamisa Iddy, Erius Tebuka, Furahini Tluway, Elisha Osati, Neema Budodi, Collins Meda, Mbonea Yonazi, Anna Schuh, Lucio Luzzatto, Julie Makani

“…Acute chest syndrome (ACS) is a life-threatening complication of sickle cell disease (SCD) with blood transfusion an integral part in its management. …”
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Lung Function Abnormalities in Sickle Cell Anaemia by Yvonne A. Dei-Adomakoh, Jane S. Afriyie-Mensah, Audrey Forson, Martin Adadey, Thomas A. Ndanu, Joseph K. Acquaye

“…Abnormalities in lung function tests have been shown to commonly occur in a majority of patients with sickle cell disease (SCD) even at steady state. The prevalence and pattern of these lung function abnormalities have been described in other populations but this is unknown among our sickle cell cohort. …”
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Fructosamine measurement for diabetes mellitus diagnosis and monitoring: a systematic review and meta-analysis protocol by Andre Pascal Kengne, Eugene Sobngwi, Jean Jacques N Noubiap, Jobert Richie N Nansseu, Joël Fokom-Domgue, Eric V Balti

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Hydroxyurea mitigates diabetic kidney disease through mTOR-S6K signaling pathway in STZ-induced diabetic mice by Wanying Cheng, Cenzhu Wang, Meican Ma, Yu Zhou

“…Hydroxyurea (HU), a sickle cell disease (SCD) drug approved by FDA, shows protective effect in nephropathy. …”
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Associations between TGF-β1 Levels and Markers of Hemolysis, Inflammation, and Tissue Remodeling in Pediatric Sickle Cell Patients by Rayra P. Santiago, Magda O. S. Carvalho, Camylla V. B. Figueiredo, Luciana M. Fiuza, Rodrigo M. Oliveira, Sètondji C. M. A. Yahouédéhou, Valma M. L. Nascimento, Isa M. Lyra, Théo Araujo-Santos, Nívea F. Luz, Milena M. Aleluia, Caroline C. Guarda, Valéria M. Borges, Marilda S. Goncalves

“…Transforming growth factor beta (TGF-β) is a cytokine with important involvement in biological processes related to the pathogenesis of sickle cell disease (SCD), including endothelial and vascular dysfunction, inflammation, and hematopoietic homeostasis. …”
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First report of serological, molecular detection, and characterization of human parvovirus B19 infections among sickle cell anaemia patients in Khartoum State, Sudan by Khalid Salman, Sittna Hayder El Nagar, Abdel Rahim M. El Hussein, Mohammed A. El Hussein, Hadi M. Yassine, Hebah A. Al Khatib, Mashael Ali Al- Badr, Ibrahim Farah, Khalid A. Enan

“…Methods: Ninety patients (aged <5 to >15 years) with sickle cell disease attending Gaafer Ibnouaf Children’s Hospital between November 2016 and February 2017 were recruited. …”
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Association between Loa loa microfilaremia and anatomical hyposplenia in a rural area of the Republic of Congo: a population-based cross-sectional study by Charlotte Boullé, Elodie Lebredonchel, Jérémy T. Campillo, Valentin Dupasquier, Marlhand C. Hemilembolo, Sébastien D. S. Pion, Jean Claude Djontu, Ludovic Rancé, Philippe Souteyrand, François Missamou, Michel Boussinesq, Francine Ntoumi, Cédric B. Chesnais

“…Blood samples were analyzed for L. loa MFD, Plasmodium-PCR, Anti-Plasmodium falciparum-IgG, total IgM, sickle-cell disease status, and hematological abnormalities. …”
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The Properties of Red Blood Cells from Patients Heterozygous for HbS and HbC (HbSC Genotype) by A. Hannemann, E. Weiss, D. C. Rees, S. Dalibalta, J. C. Ellory, J. S. Gibson

“…Sickle cell disease (SCD) is one of the commonest severe inherited disorders, but specific treatments are lacking and the pathophysiology remains unclear. …”
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