Epigenetic Mechanisms Underlying Sex Differences in Neurodegenerative Diseases by Andrea Stoccoro

“…Although the role of sex hormones and sex chromosomes in driving differential susceptibility to these diseases is well-established, the molecular alterations underlying these differences remain poorly understood. …”
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Cytokine Profile of Mouse Vaginal and Uterus Lymphocytes at Estrus and Diestrus by Maria C. Lopez, Margaret A. Stanley

“…It is known that sex hormones regulate IgA and IgG levels in the female reproductive tract. …”
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Mast Cell Activation Syndrome in COVID-19 and Female Reproductive Function: Theoretical Background vs. Accumulating Clinical Evidence by Dariusz Szukiewicz, Piotr Wojdasiewicz, Mateusz Watroba, Grzegorz Szewczyk

“…Of note, the female sex hormones estradiol (E2) and progesterone (P4) significantly influence mast cell (MC) behavior. …”
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Severe Macular Edema in Patients with Juvenile Idiopathic Arthritis-Related Uveitis by Maria Pia Paroli, Claudia Fabiani, Giovanni Spinucci, Irene Abicca, Alfredo Sapia, Leopoldo Spadea

“…In such patients, in presence of age-related microvascular changes due to the enhancer effect of sex hormones, cataract extraction should be a factor triggering the retinal complication.…”
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Effects of Yin and Yang supplement on reproductive performance, antioxidant and immunity of dairy goats by Kang Wang, Zhi Yang, Fumei Yang, Guanzong Li, Yulin Sun, Gang Duan, Jun He, Wang Sun, Ke Zhou, Zhihao Xiong, Feiyan Dai

“…These findings indicate that YYSBFF can enhance the reproductive performance of dairy goats by regulating the level of sex hormones, while also improving the body’s antioxidant and immune abilities.…”
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Acute stimulation of PBMCs drives switch from dopamine-induced anti- to proinflammatory phenotype of monocytes only in women by Leonie Fleige, Silvia Capellino

“…Moreover, B cells from men showed higher dopamine receptor (DR) expression, which was shown to be further increased by sex hormones only in men. In monocytes from women, an acute inflammatory stimulus via CpG combined with dopaminergic stimulation caused a switch to a proinflammatory phenotype, which was less pronounced in men. …”
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The Hormonal dysregulation and its consequences in Obese Women - overview by Katarzyna Maria Pala, Wiktoria Tomaszewska, Paweł Siudziński, Mateusz Łyko, Alicja Skoczylas, Maria Golińska, Anna Nowak, Jakub Kurasz, Wiktoria Podlasiewicz, Piotr Dudziak, Wojciech Maj

“…Analysis of Literature Obesity-induced chronic inflammation disrupts insulin regulation, sex hormones, and the hypothalamic-pituitary-adrenal axis. …”
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Leptin as well as Free Leptin Receptor Is Associated with Polycystic Ovary Syndrome in Young Women by Nasser M. Rizk, Elham Sharif

“…The anthropometric variables and the hormonal profile such as insulin, female and male sex hormones, and prolactin were assessed. Results. In PCOS, leptin level (ng/ml) and free leptin index (FLI) increased significantly while sOB-R (ng/ml) significantly decreased compared to control subjects. …”
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HISTOMORPHOLOGICAL ENHANCEMENT OF THE VAGINAL WALL IN DEHYDROEPIANDROSTERONE-TREATED POST-OVARIECTOMIZED WISTAR RATS by Lis Widodo Peni, Pilar Menara Falah, Yudha Nurdian

“…The exclusive source of post-menopausal sex hormones is dehydroepiandrosterone (DHEA). Purpose: Observe the impact of orally administered DHEA in the vagina of a rat (Rattus norvegicus) post- bilateral ovariectomy. …”
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Causes and Metabolic Consequences of Gynecomastia in Adult Patients by Ralitsa Robeva, Atanaska Elenkova, Sabina Zacharieva

“…Further longitudinal studies are needed to evaluate the long-term consequences of sex hormones imbalance on cardiovascular morbidity and mortality in adults with GM.…”
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Recipient sex and donor leukemic cell characteristics determine leukemogenesis in patient-derived models by Anna MP. Stanger, Marlon Arnone, Pauline Hanns, Lucca M. Kimmich, Jessica Kübler, Sarah Gekeler, Elsa S. Görsch, Lea Kramer, Marcelle Baer, Jan C. Schroeder, Taylor S. Mills, Martina Konantz, Saskia S. Rudat, Claudia Lengerke

“…Our data identify recipient sex as an important experimental confounder in leukemia PDX models, and the contribution of the sex hormones to leukemogenesis as an intriguing, underexplored research area. …”
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Amphibian newts as experimental models for studying weight gain after castration by Mai Takehara, Mitsuki Kyakuno, Kazuko Okamoto, Ichiro Tazawa, Nobuaki Furuno, Megumi Furumitsu, Kazuyoshi Ukena, Takuya Imamura, Takashi Takeuchi, Toshinori Hayashi

“…In mammals, decreases in sex hormones caused by testicular castration can affect body shape and occasionally lead to pathologies such as obesity. …”
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Gender-Related Effects of Sex Steroids on Histamine Release and FcεRI Expression in Rat Peritoneal Mast Cells by Samira Muñoz-Cruz, Yolanda Mendoza-Rodríguez, Karen E. Nava-Castro, Lilián Yepez-Mulia, Jorge Morales-Montor

“…In conclusion, MCs degranulation is modulated by sex hormones in a gender-selective fashion, with MC from females being more susceptible than MC from males to the effects of sex steroids.…”
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Implications of hormonal carcinogenesis for transgender and gender-diverse people undergoing gender-affirming hormone therapy: an up-to-date review by Matteo Lambertini, Filippo Pietrantonio, Dario Trapani, Francesco Perrone, Rossana Berardi, Saverio Cinieri, Chiara Cassani, Amelia Barcellini, Filippo Ghelardi, Alberto Giovanni Leone, Stefania Bonadonna, Marianna Sirico, Barbara Tagliaferri, Stefano Maccarone, Davide Dalu, Lorenzo Ruggieri, Simone Nardin, Nicla La Verde

“…This narrative review aims to collect and discuss evidence regarding potential correlations between GAHT and the most prevalent tumours known to be influenced by sex hormones. The objective is to comprehend how these potential carcinogenic effects impact health and inform health interventions for TGD individuals. …”
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Efficacy and Safety of Tracnil™ Administration in Patients with Dermatological Manifestations of PCOS: An Open-Label Single-Arm Study by Ezhil Arasan Ramanan, Sailatha Ravi, K. R. Radha Anbu, Margaret Michael

“…Therefore, we attribute the mechanism of action of Tracnil™ to modulation of receptor sensitivity to sex hormones or other downstream processing events. Tracnil™ may be considered as a first-line treatment for dermatological manifestations of PCOS even in the absence of significant hormonal abnormalities. …”
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Effect of Toxoplasma gondii Infection on the Level of Luteinizing and Follicle Stimulating Hormones in Women with Polycystic Ovary Syndrome by Muna Jalal Aziz, Abeer Abbas Ali, Mohammed Fadhil Hameed, Basima Ahmed Abdullah

“…Objective: To investigate the correlation between polycystic ovarian syndrome and toxoplasmosis, as well as to examine certain related sex hormones, luteinizing hormone (LH) and follicle stimulating hormone (FSH). …”
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The human‐specific noncoding RNA RP11‐424G14.1 functions at the intersection of sexually dimorphic pathways in inflammation, senescence, and metabolism by Kameron Kennicott, Yun Liang

“…Most studies on the sex bias have focused on sex hormones or female‐biased genes, whereas male‐biased genetic factors remain understudied. …”
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Bioanthropological and Biomechanical Perspectives on Skeletal Senescence Variation by Sayf Muhammad Alaydrus, Muhamad Andri Jauhari

“…Stresses in aged bone risks straining above its elastic limit and causing fractures due to its inability to tolerate such stresses. The loss of sex hormones is related to skeletal senescence, especially in females, while the effects of testosterone on skeletal senescence are under-researched. …”
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In Vitro and In Vivo Wound Healing Activity of Astragalus floccosus Boiss. (Fabaceae) by Fatemeh Akbari, Mohammad Azadbakht, Ali Bagheri, Lale Vahedi

“…Estrogens are a group of sex hormones which have receptors on the skin and lead to increased cells and wound healing. …”
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Contraceptives or Hormone Replacement Therapy and Associations with Autoimmune Conditions: Exploring Effects of Estrogen Analog Supplementation by Irakli Tskhakaia, Yurilu Gonzalez Moret, Anna‐Kay Palmer, Diego Lema, M. Carolina Musri, Nanuka Tsibadze, Arthur Lau

“…The role of estrogen, despite its protective effects against some conditions, underscores the complex interplay of sex hormones in autoimmunity. Further prospective studies are needed to elucidate underlying mechanisms and evaluate causality.…”
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