Circadian clock regulation in soybean senescence: a transcriptome analysis of early and late senescence types by Prakash Basnet, Sevin Lee, Ka Hee Moon, Nam-Il Park, Gang-Seob Lee, Seongkon Lee, Taeyoung Um, Ik-Young Choi

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Bergapten alleviates senescence of chondrocytes in osteoarthritis by YE Yuanlan, LIU Kaiwen, PAN Yiming

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Stress-Induced Premature Senescence or Stress-Induced Senescence-Like Phenotype: One In Vivo Reality, Two Possible Definitions? by Olivier Toussaint, Patrick Dumont, Jose Remacle, Jean-Francois Dierick, Thierry Pascal, Christophe Frippiat, Joao Pedro Magalhaes, Stephanie Zdanov, Florence Chainiaux

“…No consensus exists so far on the definition of cellular senescence. The narrowest definition of senescence is irreversible growth arrest triggered by telomere shortening counting cell generations (definition 1). …”
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The Hippo Signaling Pathway Manipulates Cellular Senescence by Chiharu Miyajima, Mai Nagasaka, Hiromasa Aoki, Kohki Toriuchi, Shogo Yamanaka, Sakura Hashiguchi, Daisuke Morishita, Mineyoshi Aoyama, Hidetoshi Hayashi, Yasumichi Inoue

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Ginkgetin Alleviates Inflammation and Senescence by Targeting STING by Yadan Liu, Jialin Ye, Zisheng Fan, Xiaolong Wu, Yinghui Zhang, Ruirui Yang, Bing Jiang, Yajie Wang, Min Wu, Jingyi Zhou, Jingyi Meng, Zhiming Ge, Guizhen Zhou, Yuan Zhu, Yichuan Xiao, Mingyue Zheng, Sulin Zhang

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Bioanthropological and Biomechanical Perspectives on Skeletal Senescence Variation by Sayf Muhammad Alaydrus, Muhamad Andri Jauhari

“…Senescent populations are more prone to diseases. However, aside from osteoporosis, skeletal senescence is a less discussed topic in Indonesia. …”
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Cellular Senescence as a Target in Cancer Control by Mar Vergel, Juan J. Marin, Purificacion Estevez, Amancio Carnero

“…Most tumors show unlimited replicative potential, leading to the hypothesis that cellular senescence is a natural antitumor program. Recent findings suggest that cellular senescence is a natural mechanism to prevent undesired oncogenic stress in somatic cells that has been lost in malignant tumors. …”
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Extrinsic mortality and senescence: a guide for the perplexed by de Vries, Charlotte, Galipaud, Matthias, Kokko, Hanna

“…Here we provide heuristics as well as simple models that outline when the Williams prediction holds, why there is a ‘null model’ where extrinsic mortality does not change the evolution of senescence at all, and why it is also possible to expect the opposite of William’s prediction, where increased extrinsic mortality favours slower senescence. …”
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Navigating the complex role of senescence in liver disease by Qiuting Li, Lin Wang, Yuanyuan Ji

“…Senescence is identified by a range of cellular and molecular changes, such as morphological alterations, expression of cell cycle inhibitors, senescence-associated β-galactosidase activity, and nuclear membrane changes. …”
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Arabidopsis apoplast TET8 positively correlates to leaf senescence, and tet3tet8 double mutants are delayed in leaf senescence by Jayde A. Zimmerman, Benjamin Verboonen, Andrew P. Harrison Hanson, Luis R. Arballo, Judy A. Brusslan

“…We previously noted early leaf senescence in the pen1 single and pen1pen3 double mutant. …”
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The Role of the MRG Gene Family in Replicative Senescence and Immortalization by James K. Leung, Patricia Pardo, Olivia M. Pereira-Smith

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Comprehensive Cellular Senescence Evaluation to Aid Targeted Therapies by Xiaolan Zhou, Xiaofeng Zhu, Weixu Wang, Jing Wang, Haimei Wen, Yuqi Zhao, Jiayu Zhang, Qiushi Xu, Zhaozhao Zhao, Ting Ni

“…Here, we conducted a comprehensive evaluation of cellular senescence using 7 senescence-associated gene sets. …”
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Evolutionary Explanations of the “Actuarial Senescence in the Wild” and of the “State of Senility” by Giacinto Libertini

“…However, the limits in such capacities are hardly explained in evolutionarily terms by current gerontological theories that rule out fitness decline as something genetically determined and regulated, and therefore somehow favored by natural selection.Four theories are tested as possible explanations of the “increasing mortality with increasing chronological age in populations in the wild” (“IMICAW”[1]), alias “actuarial senescence in the wild”[2], and of the observed negative correlation between extrinsic mortality and the ratio between deaths due to intrinsic mortality and deaths due to extrinsic mortality. …”
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Cellular senescence in malignant transformation of oral submucous fibrosis! by Satya Ranjan Misra, M. Sathyakumar, Pavitra Baskaran, Rupsa Das

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Role of p16INK4A in Replicative Senescence and DNA Damage-Induced Premature Senescence in p53-Deficient Human Cells by Razmik Mirzayans, Bonnie Andrais, Gavin Hansen, David Murray

“…Single-cell analysis of noncancerous human fibroblast cultures undergoing senescence as a function of culture age (replicative senescence) has revealed that p16 is not expressed in the majority (>90%) of cells that exhibit features of senescence (e.g., flattened and enlarged morphology coupled with senescence-associated β-galactosidase expression), ruling out a requirement for p16 in this process. …”
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Oxidative Stress Induced Damage and Early Senescence in Preterm Placenta by Yudianto Budi Saroyo, Noroyono Wibowo, Rima Irwinda, Ani Retno Prijanti, Evy Yunihastuti, Saptawati Bardosono, Sofie Rifayani Krisnadi, Putri Indah Permata, Stephanie Wijaya, Victor Prana Andika Santawi

“…Introduction. Senescent cells have been demonstrated to release High Mobility Group Box 1 (HMGB1) which induces labor through an inflammatory pathway. …”
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Cancer, Senescence, and Aging: Translation from Basic Research to Clinics by Matilde E. LLeonart, Amancio Carnero, Rosanna Paciucci, Zhao-Qi Wang, Noam Shomron

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Reduced PKC α Activity Induces Senescent Phenotype in Erythrocytes by Rukmini B. Govekar, Poonam D. Kawle, Suresh H. Advani, Surekha M. Zingde

“…The molecular mechanism mediating expression of senescent cell antigen-aggregated or cleaved band 3 and externalized phosphatidylserine (PS) on the surface of aged erythrocytes and their premature expression in certain anemias is not completely elucidated. …”
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Cellular senescence: from homeostasis to pathological implications and therapeutic strategies by Chunhong Li, Yixiao Yuan, YingDong Jia, Qiang Zhou, Qiang Wang, Xiulin Jiang

Subjects: “…cellular senescence…”
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Effect of Superchilling on Preservation, Ripening and Senescence of Broad Bean Seeds by LI Die, LI Haiyan, ZHONG Shihong, FU Yuansheng, LI Meiqing, ZHANG Haiwei

Subjects: “…broad bean seeds; superchilling; storage period; quality changes; ripening and senescence…”
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