Placental trophoblast aging in advanced maternal age is related to increased oxidative damage and decreased YAP by Song Guo, Song Guo, Qihao Pan, Qihao Pan, Baokang Chen, Baokang Chen, Yijuan Huang, Yijuan Huang, Si Li, Si Li, Chenyu Gou, Chenyu Gou, Yu Gao, Yu Gao

“…Cellular experiments demonstrated that oxidative damage from H2O2 triggered trophoblast cell senescence and resulted in a reduction of YAP levels. …”
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Isolation and Characterisation of Mesenchymal Stem Cells from Rat Bone Marrow and the Endosteal Niche: A Comparative Study by Norhayati Yusop, Paul Battersby, Amr Alraies, Alastair J. Sloan, Ryan Moseley, Rachel J. Waddington

“…Both populations exhibited consistent telomere lengths (12–17 kb), minimal senescence, and positive telomerase expression. CB-MSCs (PD15) had significantly lower CFEs than PD50. …”
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Immune Activation, Immunosenescence, and Osteoprotegerin as Markers of Endothelial Dysfunction in Subclinical HIV-Associated Atherosclerosis by Alessandra D’Abramo, Maria Antonella Zingaropoli, Alessandra Oliva, Claudia D’Agostino, Samir Al Moghazi, Giulia De Luca, Marco Iannetta, Claudio Maria Mastroianni, Vincenzo Vullo

“…CD4+/CD8+ T-cell activation (CD38+ HLADR+) and senescence (CD57+ CD28−) were measured by flow cytometry. …”
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SLC29A1 and SLC29A2 are human nicotinamide cell membrane transporters by Mingyang Chen, Luexiang Yuan, Binxin Chen, Hui Chang, Jun Luo, Hengbin Zhang, Zhongjian Chen, Jiao Kong, Yaodong Yi, Mengru Bai, Minlei Dong, Hui Zhou, Huidi Jiang

“…Changes to cellular respiration, mitochondrial status and senescence by ENT1/2 knockdown are reversed by NMN supplementation. …”
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Adhesive and injectable hydrogel microspheres for NRF2-mediated periodontal bone regeneration by Yu Wang, Shanshan Jin, Yaru Guo, Yilong Lu, Xuliang Deng

“…Mechanistically, MMS-CY inhibited the premature senescence induced by the inflammation stimulus through the nuclear factor erythroid 2-related factor (NRF2) pathway and reducing the DNA injury. …”
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Insights Into the Role of Bmi‐1 Deregulation in Promoting Stemness and Therapy Resistance in Glioblastoma: A Narrative Review by Fatima Shaalan, Nissrine Ballout, Wafaa Takash Chamoun

“…In addition, Bmi‐1 confers radioresistance and chemotherapy by promoting cell senescence evasion and DNA repair. Conclusion Bmi‐1 regulates self‐renewal, proliferation, and differentiation of GBM cells, promoting stemness and therapy resistance. …”
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N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1 by Li Xu, Shuo Chen, Qiuling Fan, Yonghong Zhu, Hang Mei, Jiao Wang, Hongyuan Yu, Ying Chen, Fan Liu

“…Abstract Background Age-related kidney impairment, characterized by tubular epithelial cell senescence and renal fibrosis, poses a significant global public health threat. …”
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Postnatal expression of Cat-315-positive perineuronal nets in the SAMP10 mouse primary somatosensory cortex by Hiroshi Ueno, Yu Takahashi, Sachiko Mori, Eriko Kitano, Shinji Murakami, Kenta Wani, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara

“…We compared these results with those of senescence-accelerated mouse-resistant (SAMR) mice. …”
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Empirical Evidence for Various Evolutionary Hypotheses on Species Demonstrating Increasing Mortality with Increasing Chronological Age in the Wild by Giacinto Libertini

“…In particular, (1) the existence of many species with a constant, or almost constant, mortality rate, especially the so-called “animals with negligible senescence”; (2) the inverse correlation, observed in mammals and birds in the wild, between extrinsic mortality and the proportion of deaths due to intrinsic mortality; (3) the existence of highly sophisticated, genetically determined, and regulated mechanisms that limit and modulate cell duplication capacities and overall cell functionality. …”
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BRCA1 is involved in sustaining rapid antler growth possibly via balancing of the p53/endoplasmic reticulum stress signaling pathway by Qianqian Guo, Zhen Wang, Jiping Li, Chao Ma, Junjun Zheng, Hengxing Ba, Guokun Zhang, Chunyi Li

“…Lack of BRCA1 promoted cell apoptosis and cell senescence and inhibited cell proliferation and cell self-renewal. …”
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The Long and Short of It: The Role of Telomeres in Fetal Origins of Adult Disease by Stephanie E. Hallows, Timothy R. H. Regnault, Dean H. Betts

“…The etiology of these diseases is beginning to be elucidated, and premature aging or cellular senescence through increased oxidative stress and DNA damage to telomeric ends may be initiators of these disease processes. …”
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Ecogeographical Amplitude and Habitat of Two Species of the Genus- <i>Terminalia</i> (Combretaceae) In the Central Niger Delta Areas in Rivers State by NL Edwin-Wosu, T Omara-Achong, BL Nyannanyo

“…Both species are deciduous with annual foliar senescence. Both species were also observed to be utilized for different purposes such as environmental conservation, beautification, parks and habitat and as shade creating plants and domestic source of fuel in the Central Niger Delta…”
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Asymmetric Cell Kinetics Genes: The Key to Expansion of Adult Stem Cells in Culture by James L. Sherley

“…One overlooked reason for this difficulty may be the inherent asymmetric cell kinetics of stem cells in postnatal somatic tissues. Senescence is the expected fate of a culture whose growth depends on adult stem cells that divide with asymmetric cell kinetics. …”
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Targeting the Mitotic Catastrophe Signaling Pathway in Cancer by Margaret M. Mc Gee

“…Mitotic catastrophe, as defined in 2012 by the International Nomenclature Committee on Cell Death, is a bona fide intrinsic oncosuppressive mechanism that senses mitotic failure and responds by driving a cell to an irreversible antiproliferative fate of death or senescence. Thus, failed mitotic catastrophe can promote the unrestrained growth of defective cells, thereby representing a major gateway to tumour development. …”
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Sycamore Lace Bug, Corythucha ciliata (Say) (Insecta: Hemiptera: Tingidae) by Susan E. Halbert, James R. Meeker

“…The bugs feed on the undersides of the leaves, initially causing a white stippling that can eventually progress into chlorotic or bronzed foliage and premature senescence of leaves. In cases of severe infestations, trees may be defoliated in late summer. …”
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Sycamore Lace Bug, Corythucha ciliata (Say) (Insecta: Hemiptera: Tingidae) by Susan E. Halbert, James R. Meeker

“…The bugs feed on the undersides of the leaves, initially causing a white stippling that can eventually progress into chlorotic or bronzed foliage and premature senescence of leaves. In cases of severe infestations, trees may be defoliated in late summer. …”
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Reproductive aging in farm animals: Impacts on fertility and strategies for mitigation: A narrative review by Akhter Rasool, Sachin, Irtiqa Manzoor, Akshata Patil

“…This decline is exacerbated by oxidative stress and mitochondrial dysfunction, leading to reproductive senescence and reduced offspring viability. Understanding the mechanisms of reproductive aging and developing strategies to mitigate its effects are crucial for enhancing livestock productivity and sustaining the agrarian economy.…”
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Phase I trial of hydroxychloroquine to enhance palbociclib and letrozole efficacy in ER+/HER2− breast cancer by Akshara Singareeka Raghavendra, Nicole M. Kettner, Danielle Kwiatkowski, Senthil Damodaran, Yan Wang, David Ramirez, Dan S. Gombos, Kelly K. Hunt, Yu Shen, Khandan Keyomarsi, Debu Tripathy

“…Previously, we demonstrated that low doses of palbociclib activate autophagy, reversing initial G1 cell cycle arrest, while high concentrations induce off-target senescence. The autophagy inhibitor hydroxychloroquine (HCQ) induced on-target senescence at lower palbociclib doses. …”
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Stemness Maintenance Properties in Human Oral Stem Cells after Long-Term Passage by Francesca Diomede, Thangavelu Soundara Rajan, Valentina Gatta, Marco D’Aurora, Ilaria Merciaro, Marco Marchisio, Aurelio Muttini, Sergio Caputi, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

“…Cell proliferation assay showed no difference between early and late passages while senescence markers p16 and p21 were considerably increased in late passage. …”
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Negative Aging Self-stereotypes and Aging Perceptions beyond a Holistic Perspective by Feba John, P. V. Athiramol, Ramalingam Kameswaran, Krishnaveni Kandasamy

“…The concept of “self-perceptions of senescence” refers to how individuals view their own aging process, with successful aging characterized by good physical and cognitive functioning, absence of illness, and socialization. …”
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