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321
Neuroinflammation in Autism: Plausible Role of Maternal Inflammation, Dietary Omega 3, and Microbiota
Published 2016-01-01“…., attention deficit hyperactivity disorder (ADHD) and schizophrenia). Interestingly, PUFAs, and specifically n-3 PUFAs, are powerful immunomodulators that exert anti-inflammatory properties. …”
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322
Acute Necrotizing Pancreatitis following Long-Term Antipsychotic Use
Published 2021-01-01“…We present a case of a patient with treatment-resistant schizophrenia managed for over a decade on olanzapine and haloperidol. …”
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323
Hippocampal Regulation of Postsynaptic Density Homer1 by Associative Learning
Published 2017-01-01“…Genes involved in synaptic plasticity, particularly genes encoding postsynaptic density proteins, have been recurrently linked to psychiatric disorders including schizophrenia and autism. Postsynaptic density Homer1 proteins contribute to synaptic plasticity through the competing actions of short and long isoforms. …”
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324
Awareness and attitudes of pregnant women concerning genetic disorders and pregnancy termination in northeastern Iran
Published 2025-01-01“…Age was associated with conditions such as epilepsy, congenital blindness, schizophrenia, and severe LDMH. Furthermore, a history of anomalies in previous pregnancies was linked to Klinefelter syndrome, Turner syndrome, dwarfism, and quadriplegia. …”
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325
Multimorbidity clusters and associated health care cost among patients attending psychiatric clinics in Odisha, India
Published 2023-07-01“…Three clusters of patients identified using the 2nd approach were identified: 1) those with mood disorders and cardiometabolic, musculoskeletal, and thyroid diseases; 2) those with neurotic, substance use, and organic mental disorders, cancer, and epilepsy; and 3) those with Schizophrenia. Patients in Cluster 1 were taking more than six medicines and had more hospital visits. …”
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326
Modelling sensory attenuation as Bayesian causal inference across two datasets.
Published 2025-01-01“…Computational models of sensory attenuation may help to bridge the gap across different sensory modalities and experimental paradigms and may contribute towards an improved description and understanding of deficits in specific patient groups (e.g. schizophrenia).…”
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327
SPERM QUALITY IN RATS PREDISPOSED TO THE MANIFESTATION OF CATATONIC REACTIONS
Published 2018-07-01“…Catatonia is a sign of many menthal disorders, particularly schizophrenia and depression, with a wide disrtibution in the human population. …”
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328
Phytocanabinoids and synthetic cannabinoids: from recreational consumption to potential therapeutic use – a review
Published 2025-01-01“…The behavioral and physiological effects of cannabinoids have received particular attention over the last few decades, including sensations of euphoria, relaxation and loss of concentration, with their repeated use being associated with short and long-term side effects, including respiratory and cardiovascular disorders, cognitive changes, psychoses, schizophrenia and mood disorders. On the other hand, recent investigations have proposed a promising therapeutic potential of cannabinoid-based drugs for a wide range of medical situations, including neurological and psychiatric disorders, among other indications. …”
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329
Movement in the Shadow of Sadness: How Physical Activity Supports the Fight Against Depression
Published 2025-02-01“…Research indicates that regular physical exercise, such as aerobic or strength training, aids in the prevention and treatment of mental disorders such as depression, schizophrenia, and Alzheimer’s disease. The biological mechanisms associated with physical activity include improved cerebral blood flow, modulation of neurotransmitter systems, and increased levels of neurotrophic factors like BDNF. …”
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330
Modulation of Adult Hippocampal Neurogenesis by Early-Life Environmental Challenges Triggering Immune Activation
Published 2014-01-01“…A rising number of research studies have shown that activation of the immune system in early life can augment the risk of some psychiatric disorders in adulthood, such as schizophrenia and depression. The mechanisms of such a developmental programming effect are unknown; however some preliminary evidence is emerging in the literature, which suggests that adult hippocampal neurogenesis may be involved. …”
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331
Human lineage mutations regulate RNA-protein binding of conserved genes NTRK2 and ITPR1 involved in human evolution
Published 2024-06-01“…These genes also carried excess damaging coding mutations that caused neurodevelopmental disorders, ataxia and schizophrenia. Among these genes, NTRK2 and ITPR1 had the most aggregated evidence of functional importance, suggesting their essential roles in cognition and bipedalism.Conclusions Our findings suggest that a small subset of human-specific mutations have contributed to human speciation through impacts on post-transcriptional modification of critical brain-related genes.…”
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332
Comparing Family Functioning and Maternal Anxiety in Children with Attention and Hyperactivity Disorder and Controls
Published 2015-12-01“…The Kiddie Schedule for Affective Disorders and Schizophrenia for School Aged Children- Present and Lifetime Version (K-SADS-PL) was used to diagnose ADHD and allowed comorbidities. …”
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333
Changes in RNA Splicing: A New Paradigm of Transcriptional Responses to Probiotic Action in the Mammalian Brain
Published 2025-01-01“…Using the PsyGeNET platform, we found that DSGs from the locus coeruleus (LConly), medial preoptic area (mPOA), and ventral dentate gyrus (venDG) were enriched in depression-associated or schizophrenia-associated genes. Notably, we highlight the <i>App</i> gene, where Lacidofil<sup>®</sup> precisely regulated the splicing of two exons causally involved in amyloid β protein-based neurodegenerative diseases. …”
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334
Endocervical miRNA-142 expression in patients with pelvic inflammatory disease positive for Chlamydia trachomatis
Published 2024-01-01“…Changes in miRNA expression have been identified in many diseases, such as cardiac and autoimmune disorders, schizophrenia, and cancer. In this cross-sectional pilot investigation, samples were taken from control women who were not infected and from symptomatic women who were infected with C. trachomatis. …”
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335
The clinical profile and outcome of patients receiving continuation electroconvulsive therapy (C-ECT): A retrospective study
Published 2023-06-01“…The most common diagnosis was schizophrenia (73.3%), followed by recurrent depressive disorder (21.6%). …”
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336
Mycobacterium neoaurum Bloodstream Infection Associated with a Totally Implanted Subclavian Port in an Adult with Diabetes and History of Colon Cancer
Published 2020-01-01“…A 66-year-old male with schizophrenia, type 2 diabetes mellitus, and a history of excision and chemotherapy to treat adenocarcinoma of the colon 6 years prior, presented with fever and behavioral changes. …”
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337
Highlights of 2023-Print Issue
Published 2023-12-01“…Additional features include • A [safety alert about clozapine](https://patientsafetyj.com/article/90674), a last-line therapy for schizophrenia that may cause serious, life-threatening side effects if it is not dosed appropriately • Data analyses from the largest event reporting database of its kind in the United States, including [patient safety trends in serious events and incidents](https://patientsafetyj.com/article/74752), and [healthcare-associated infections in nursing homes](https://patientsafetyj.com/article/74494) • An interview with pediatrician Dr. …”
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338
Testing the Psychometric Properties of a Chinese Version of the Level of Expressed Emotion Scale
Published 2014-01-01“…The mean scores of the overall and subscale of the Chinese version in patients with unipolar disorder were higher than in other illness groups (schizophrenia, psychotic disorders, and bipolar disorder; P<0.01). …”
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339
Modulation of Second Messenger Signaling in the Brain Through PDE4 and PDE5 Inhibition: Therapeutic Implications for Neurological Disorders
Published 2025-01-01“…Elevated PDE4 activity impairs synaptic plasticity by reducing cAMP levels and protein kinase A (PKA) activity, contributing to cognitive decline, acute brain injuries, and neuropsychiatric conditions such as bipolar disorder and schizophrenia. Similarly, PDE5 dysregulation disrupts nitric oxide (NO) signaling and protein kinase G (PKG) pathways, which are involved in cerebrovascular homeostasis, recovery after ischemic events, and neurodegenerative processes in Alzheimer’s, Parkinson’s, and Huntington’s diseases. …”
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340
Clozapine-Induced Late Agranulocytosis and Severe Neutropenia Complicated with Streptococcus pneumonia, Venous Thromboembolism, and Allergic Vasculitis in Treatment-Resistant Femal...
Published 2015-01-01“…Clozapine is a second-generation antipsychotic agent from the benzodiazepine group indicated for treatment-resistant schizophrenia and other psychotic conditions. Using clozapine earlier on once a case appears to be refractory limits both social and personal morbidity of chronic psychosis. …”
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