Hyperlipidemia May Synergize with Hypomethylation in Establishing Trained Immunity and Promoting Inflammation in NASH and NAFLD by Charles I. V. Drummer, Fatma Saaoud, Yu Sun, Diana Atar, Keman Xu, Yifan Lu, Ying Shao, Candice Johnson, Lu Liu, Huimin Shen, Nirag C. Jhala, Xiaohua Jiang, Hong Wang, Xiaofeng Yang

“…We performed a panoramic analysis on both human nonalcoholic steatohepatitis (NASH) microarray data and microarray/RNA-seq data from various mouse models of nonalcoholic fatty liver disease NASH/NAFLD with total 4249 genes examined and made the following findings: (i) human NASH and NAFLD mouse models upregulate both cytokines and chemokines; (ii) pathway analysis indicated that human NASH can be classified into metabolic and immune NASH; methionine- and choline-deficient (MCD)+high-fat diet (HFD), glycine N-methyltransferase deficient (GNMT-KO), methionine adenosyltransferase 1A deficient (MAT1A-KO), and HFCD (high-fat-cholesterol diet) can be classified into inflammatory, SAM accumulation, cholesterol/mevalonate, and LXR/RXR-fatty acid β-oxidation NAFLD, respectively; (iii) canonical and noncanonical inflammasomes play differential roles in the pathogenesis of NASH/NAFLD; (iv) trained immunity (TI) enzymes are significantly upregulated in NASH/NAFLD; HFCD upregulates TI enzymes more than cytokines, chemokines, and inflammasome regulators; (v) the MCD+HFD is a model with the upregulation of proinflammatory cytokines and canonical and noncanonical inflammasomes; however, the HFCD is a model with upregulation of TI enzymes and lipid peroxidation enzymes; and (vi) caspase-11 and caspase-1 act as upstream master regulators, which partially upregulate the expressions of cytokines, chemokines, canonical and noncanonical inflammasome pathway regulators, TI enzymes, and lipid peroxidation enzymes. …”
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Streamlined photoacoustic image processing with foundation models: A training-free solution by Handi Deng, Yucheng Zhou, Jiaxuan Xiang, Liujie Gu, Yan Luo, Hai Feng, Mingyuan Liu, Cheng Ma

“…We employed the Segment Anything Model (SAM) by setting simple prompts and integrating the model’s outputs with prior knowledge of the imaged objects to accomplish various tasks, including: (1) removing the skin signal in three-dimensional PA image rendering; (2) dual speed-of-sound reconstruction, and (3) segmentation of finger blood vessels. …”
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Developing the Ready Military Medical Force: military-specific training in Graduate Medical Education by John B Holcomb, Jan O Jansen, Eric A Elster, Matthew D Tadlock, Jennifer M Gurney, Emily W Baird, Daniel T Lammers, Richard D Betzold, Shaun R Brown, Matthew J Eckert, Daniel B Cox, Jeffrey D Kerby

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Comparison of Two Field Deployable PCR Platforms for SARS-CoV-2 and Influenza A and B Viruses’ Detection by Hakim Bouamar, Grace M. Reed, Wanda Lyon, Hector Lopez, Anna Ochoa, Susana N. Asin

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Uticaj brdsko-planinskih vodotoka na traktorske puteve/ vlake, studij slučaja by Muhamed Bajrić, Amina Čaluk, Aldin Vranović, Vladimir Petković

“…Također, i sama infrastruktura može negativno djelovati na prirodni tok, te kao posljedicu lošeg rješenja trase preusmjeriti isti traktorskim putem ili traktorskom vlakom. Sam način izgradnje traktorskih puteva/vlaka, pri čemu se izvode samo zemljani radovi bez izgradnje objekata za podužnu i poprečnu odvodnju površinskih i oborinskih voda, stvara optimalne preduslove za razvijanje erozionih procesa različitog intenziteta. …”
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Attention-enhanced optimized deep ensemble network for effective facial emotion recognition by Taimoor Khan, Muhammad Yasir, Chang Choi

“…Subsequently, the channel attention module (CAM) and spatial attention module (SAM) are sequentially incorporated in the framework for dominant feature selection. …”
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Advancing Underwater Vision: A Survey of Deep Learning Models for Underwater Object Recognition and Tracking by Mahmoud Elmezain, Lyes Saad Saoud, Atif Sultan, Mohamed Heshmat, Lakmal Seneviratne, Irfan Hussain

“…State-of-the-art (SOTA) models, including AGW-YOLOv8, Feature-Adaptive FPN, and Dual-SAM, have shown substantial improvements in addressing occlusions, camouflaging, and small underwater object detection. …”
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A Novel Approach to Optimize Key Limitations of Azure Kinect DK for Efficient and Precise Leaf Area Measurement by Ziang Niu, Ting Huang, Chengjia Xu, Xinyue Sun, Mohamed Farag Taha, Yong He, Zhengjun Qiu

“…The semantic information was extracted using a joint YOLOv11-SAM2 model, which utilizes supervised object recognition prompts and advanced visual large models to achieve precise RGB image semantic parsing with minimal manual input. …”
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Analiza rynku i potrzeb sektora małych i średnich przedsiębiorstw w kontekście zarządzania płynnością finansową by Kinga Bednarzewska

“…W wyniku tego pojawia się tzw. łańcuch zadłużeń, który polega na tym, że jeżeli jeden podmiot nie otrzymuje należnych mu pieniędzy w terminie, to nie ma on również środków, którymi mógłby spłacić własne zobowiązania wobec innego podmiotu. Ten z kolei ma ten sam problem w stosunku do kolejnego. Wskutek tego powstają zatory płatnicze. …”
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Acute Reciprocal Changes Distant from the Site of Spinal Osteotomies Affect Global Postoperative Alignment by Eric Klineberg, Frank Schwab, Christopher Ames, Richard Hostin, Shay Bess, Justin S. Smith, Munish C. Gupta, Oheneba Boachie, Robert A. Hart, Behrooz A. Akbarnia, Douglas C. Burton, Virginie Lafage

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The Relationship between the Depression and Anxiety Stress Survey Questionnaire, Salivary Cortisol and Heart Rate Variability by Fateme Sangtarash, Haniyeh Choobsaz, Milad Zarrin, Sousan Salari, Ehsan Mokari Manshadi, Ali Akbar Esmaeili, Sayyed Hossein Mozaffari, Boshra Hatef

“…Conclusion: The anxiety-DASS subscale represents the sympathetic-adrenal medulla (SAM) activity. Clinicians can estimate the activity of this stress axis by using the anxiety subscale of the DASS questionnaire. …”
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Comparison of the risk of obesity in the FTO rs9939609 genotype in a multiethnic group in Asia systematic review and meta-analysis by Donna Pratiwi, Miko Sidartha, Elvan Wiyarta, Elvan Wiyarta, I Wayan Agustinus Harimawan, Ni Made Dwi Asti Lestari, Bonglee Kim, Nurpudji Astuti Taslim, Trina Ekawati Tallei, Fahrul Nurkolis, Rony Abdi Syahputra

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Postnatal expression of Cat-315-positive perineuronal nets in the SAMP10 mouse primary somatosensory cortex by Hiroshi Ueno, Yu Takahashi, Sachiko Mori, Eriko Kitano, Shinji Murakami, Kenta Wani, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara

“…We have previously reported that Cat-315-positive molecules were not expressed in the PNNs of the senescence-accelerated model (SAM)P10 strain model mice at 12 months of age. To confirm whether the loss of Cat-315-positive molecules occurred early in life in SAMP10 mice, we examined Cat-315-positive PNNs in the primary somatosensory cortex during postnatal development. …”
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Ecotoxicological insight of phytochemicals, toxicological informatics, and heavy metal concentration in Tridax procumbens L. in geothermal areas by N.B. Maulydia, R. Idroes, K. Khairan, T.E. Tallei, F. Mohd Fauzi

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Guia Beabá do Câncer: Validação de Livro Educativo para Crianças, Famílias e Profissionais de Saúde by Simone Lehwess Mozzilli, Pedro Emílio Gomes Prates, Isadora Cardoso Salles Fila Pecenin, Lucas Thiago Pereira da Silva, Marina de Góes Salvetti

“…Método: Estudo metodológico de validação de conteúdo utilizando o método Suitability Assessment of Materials (SAM) para avaliar a adequação do material em seis categorias (conteúdo, linguagem, ilustração, apresentação, motivação e adaptação cultural) e indicadores da experiência do usuário. …”
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Detection of I491F and V170F rpoB mutations associated with misdiagnosis of rifampicin resistance among patients with drug-susceptible tuberculosis treatment failure, Myanmar, 2022 by Phyu Win Ei, Mi Mi Htwe, Myat Htut Nyunt, Aye Su Mon, Zaw Myint, Wint Wint Nyunt, Su Mon Win, Sandar Aung, Wai Myat Thwe, Wah Wah Aung

“…Mutation analysis was done by PhyResSE and SAM-TB online platforms. Results: A total of 32 culture-positive isolates with DNA qualified for genome sequencing were included in the study. …”
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Kontemplacja mistyczna w ujęciu św. Jana od Krzyża by Jerzy Wiesław Gogola

“…Są one doświadczane przez wielu wierzących, ale nie w taki sam sposób i nie w takiej samej proporcji. Zakładając autentyczną wierność wierzącego, przy różnej formie przeżywania relacji z Bogiem i dokonujących się duchowych procesów, należy stwierdzić, że zależy to od Bożej pedagogii. …”
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Changes in Techno-Functional Characteristics of Cow Colostrum Powder Prepared by Freeze Drying by Anamika Das, Raman Seth, Ayon Tarafdar, Swarnima Dey, Yogesh Kumar, Ranjna Sirohi

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NutriLive: An Integrated Nutritional Approach as a Sustainable Tool to Prevent Malnutrition in Older People and Promote Active and Healthy Ageing—The EIP-AHA Nutrition Action Group... by Maddalena Illario, Angela Serena Maione, Maria Rosaria Rusciano, Edwig Goossens, Amelia Rauter, Nidia Braz, Harriet Jager-Wittenaar, Carolina Di Somma, Catherine Crola, Maria Soprano, Laura Vuolo, Pietro Campiglia, Guido Iaccarino, Helen Griffiths, Tobias Hartman, Donatella Tramontano, Annamaria Colao, Regina Roller-Wirnsberger

“…“NutriLive” is an integrated nutritional approach, represented by a structured Screening-Assessment-Monitoring-Action-Pyramid-Model (SAM-AP). Its core concept is the stratification of the nutritional needs, considered by the working group as the key for targeted, effective, and sustainable interventions. …”
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Sustained Weight Loss with Vagal Nerve Blockade but Not with Sham: 18-Month Results of the ReCharge Trial by Scott A. Shikora, Bruce M. Wolfe, Caroline M. Apovian, Mehran Anvari, David B. Sarwer, Robert D. Gibbons, Sayeed Ikramuddin, Christopher J. Miller, Mark B. Knudson, Katherine S. Tweden, Michael G. Sarr, Charles J. Billington

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