Sir2 and Fun30 regulate ribosomal DNA replication timing via MCM helicase positioning and nucleosome occupancy by Carmina Lichauco, Eric J Foss, Tonibelle Gatbonton-Schwager, Nelson F Athow, Brandon Lofts, Robin Acob, Erin Taylor, James J Marquez, Uyen Lao, Shawna Miles, Antonio Bedalov

“…The association between late replication timing and low transcription rates in eukaryotic heterochromatin is well known, yet the specific mechanisms underlying this link remain uncertain. In Saccharomyces cerevisiae, the histone deacetylase Sir2 is required for both transcriptional silencing and late replication at the repetitive ribosomal DNA (rDNA) arrays. …”
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On the Biosynthesis of Bioactive Tryptamines in Black Cohosh (<i>Actaea racemosa</i> L.) by Martin J. Spiering, James F. Parsons, Edward Eisenstein

“…Expression of black cohosh <i>TDC1</i>, <i>TDC2</i>, and <i>TDC3</i> in <i>Saccharomyces cerevisiae</i> resulted in the production of tryptamine. …”
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Effects of live yeast on milk yield, feed efficiency, methane emissions and fertility of high-yielding dairy cows by P.C. Garnsworthy, N. Saunders, J.R. Goodman, I.H. Algherair, J.D. Ambrose

“…Live yeast (Saccharomyces cerevisiae) products have the potential to increase milk yield of dairy cows in early lactation by improving rumen fermentation. …”
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Banana plant waste composting through microbial inoculation and its performance in spinach by Likhesh Kumar Verma, Kishan Kumar Raj, Dippal, Safina Ismail, Tapas Chowdhury, Ravindra Soni

“…Method: Banana plant waste and vegetable waste composting were evaluated through microbial inoculation with bacteria Pseudomonas aeruginosa AMBCD-1 and yeast (Saccharomyces cerevisiae) for about 45 days. Further the assessments of physicochemical properties of biodegraded compost were analyzed. …”
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The Impact of Grape Maceration on Quality and Biogenic Amine Formation in Slovak Tokaj Wines: Examination of Microbial, Chemical and Sensory Properties by Boris Semjon, Martin Bartkovský, Peter Očenáš, Ivana Regecová, Zuzana Megyesy Eftimová, Jana Výrostková, Lýdia Mesarčová, Mariana Kováčová, Matúš Várady, Lucia Šuľáková, Slavomír Marcinčák

“…The aim of this research was to analyse the effect of two maceration practices—one utilizing the application of a <i>Saccharomyces cerevisiae</i> culture and the other being maceration without a yeast culture in experimental Lipovina (<i>Vitis vinifera</i> L.) white wine from the Slovak part of the Tokaj region. …”
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Creation of a recombinant Komagataella phaffii strain, a producer of proteinase K from Tritirachium album by A. B. Beklemishev, M. B. Pykhtina, Ya. M. Kulikov, T. N. Goryachkovskaya, D. V. Bochkov, S. V. Sergeeva, A. R. Vasileva, V. P. Romanov, D. S. Novikova, S. E. Peltek

“…The proteinase K gene was inserted into pPICZα-A in such a way that – at a subsequent stage of transfection into yeast cells – it was efficiently expressed under the control of the promoter and terminator of the AOX1 gene, and the product of the exogenous gene contained the signal peptide of the Saccharomyces cerevisiae a-factor to ensure the protein’s secretion into the culture medium. …”
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The Legionella pneumophila effector PieF modulates mRNA stability through association with eukaryotic CCR4−NOT by Harley O'Connor Mount, Malene L. Urbanus, Francesco Zangari, Anne-Claude Gingras, Alexander W. Ensminger

“…Heterologous expression of PieF phenocopies knockout of the CNOT7 ortholog (POP2) in Saccharomyces cerevisiae, resulting in 6-azauracil sensitivity. …”
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The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases by Geordan J. Stukey, Matthew R. Breuer, Natalie Burchat, Ruta Jog, Kollin Schultz, Gil-Soo Han, Matthew S. Sachs, Harini Sampath, Ronen Marmorstein, George M. Carman

“…We identified that the antidepressant sertraline is a novel inhibitor of PAP. Using Saccharomyces cerevisiae Pah1 as a model PAP, sertraline inhibited the activity by a noncompetitive mechanism. …”
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Coupling genome-wide continuous perturbation with biosensor screening reveals the potential targets in yeast isopentanol synthesis network by Qi Xiao, Jingjing Shi, Lixian Wang, Guoping Zhao, Yanfei Zhang

“…The F2 strain, in particular, achieved an isopentanol titer of 1.57 ± 0.014 g/L and a yield of 14.04 ± 0.251 mg/g glucose (10% glucose), surpassing the highest values reported to date in engineered Saccharomyces cerevisiae. Systematic transcriptome analysis of the isopentanol synthesis, glycolysis, glycerol metabolism, and ethanol synthesis pathways revealed that MPC, OAC1, BAT2, GUT2, PDC6, and ALD4 are linked to efficient isopentanol production. …”
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Dual regulation of the levels and function of Start transcriptional repressors drives G1 arrest in response to cell wall stress by Mihai Spiridon-Bodi, Cristina Ros-Carrero, J. Carlos Igual, Mercè Gomar-Alba

“…Methods The response of Saccharomyces cerevisiae to Calcofluor White was investigated to characterize the regulation and function of Whi7 and Whi5 under cell wall stress. …”
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MsCL-P1: A multifunctional C-type lectin from largemouth bass (Micropterus salmoides) with broad microbe binding and agglutination activities by Siyi She, Ying Ye, Fengyao Guo, Shun Yang, Mengmeng Huang, Hui Fei

“…Agglutination assays revealed that rCRD could agglutinate Aeromonas veronii and Saccharomyces cerevisiae, but not Micrococcus luteus. Carbohydrate binding specificity assays indicated that rCRD's agglutination activity could be suppressed by D-mannose and D-galactose. …”
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Template switching during DNA replication is a prevalent source of adaptive gene amplification by Julie N Chuong, Nadav Ben Nun, Ina Suresh, Julia Cano Matthews, Titir De, Grace Avecilla, Farah Abdul-Rahman, Nathan Brandt, Yoav Ram, David Gresham

“…Previously, we found the GAP1 gene in Saccharomyces cerevisiae undergoes frequent amplification and selection in glutamine-limitation. …”
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Artisanal and farmer bread making practices differently shape fungal species community composition in French sourdoughs by Michel, Elisa, Masson, Estelle, Bubbendorf, Sandrine, Lapicque, Léocadie, Nidelet, Thibault, Segond, Diego, Guézenec, Stéphane, Marlin, Thérèse, Devillers, Hugo, Rué, Olivier, Onno, Bernard, Legrand, Judith, Sicard, Delphine

“…The well-known bakery yeast, Saccharomyces cerevisiae, was dominant (i.e. with a relative abundance over 50%) in only 24% of sourdoughs while other yeast species, belonging to the Kazachstania genus, were dominant in 54% of sourdoughs. …”
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Mannan-Binding Lectin Suppresses Peptidoglycan-Induced TLR2 Activation and Inflammatory Responses by Fanping Wang, Yanhua Li, Can Yang, Yonghui Mu, Yan Wang, Wei Zhang, Yonghui Yang, Chen Chen, Shijun Song, Zhifa Shen, Wenjun Wang, Junpeng Li, Jingjing Zhai, Kang Guo, Ruili Sun, Lili Yu, Mingyong Wang

“…These results supplied the evidence that PGN from Saccharomyces cerevisiae could be recognized by TLR2. In addition, we also found that MBL decreased PGN-induced TLR2 expression and suppressed TLR2-mediated downstream signaling, including the phosphorylation of IκBα, nuclear translocation of NF-κBp65, and phosphorylation of MAPK p38 and ERK1/2. …”
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Optogenetic control of horizontally acquired genes prevent stuck fermentations in yeast by David Figueroa, Diego Ruiz, Nicolò Tellini, Matteo De Chiara, Eduardo I. Kessi-Pérez, Claudio Martínez, Gianni Liti, Amparo Querol, José M. Guillamón, Francisco Salinas

“…ABSTRACT Nitrogen limitations in the grape must be the main cause of stuck fermentations during the winemaking process. In Saccharomyces cerevisiae, a genetic segment known as region A, which harbors 12 protein-coding genes, was acquired horizontally from a phylogenetically distant yeast species. …”
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Sdd3 regulates the biofilm formation of Candida albicans via the Rho1-PKC-MAPK pathway by Li Mei Pang, Guisheng Zeng, Eve Wai Ling Chow, Xiaoli Xu, Ning Li, Yee Jiun Kok, Shu Chen Chong, Xuezhi Bi, Jiaxin Gao, Chaminda Jayampath Seneviratne, Yue Wang

“…One identified gene is ORF19.6693, a homolog of the Saccharomyces cerevisiae SDD3 gene. The sdd3∆/∆ mutant exhibited severe defects in biofilm formation and significantly reduced chitin content in the cell wall. …”
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Lactobacillus fermentum as a new inhibitor to control advanced glycation end-product formation during vinegar fermentation by Qin Li, Leibing Li, Hanjian Zhu, Fan Yang, Ke Xiao, Lin Zhang, Menglin Zhang, Yongsheng Peng, Chao Wang, Dongsheng Li, Qian Wu, Mengzhou Zhou

“…The selected LAB strains were separately co-cultivated with Saccharomyces cerevisiae and Acetobacter pasteurianus 1.41 in alcoholic and acetic acid fermentation, respectively. …”
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Hybrid azole-based conjugates as upcoming anticancer and antimicrobial agents by Luís M. T. Frija, Bruno E. C. Guerreiro, Inês C. C. Costa, Vera M. S. Isca, Lucília Saraiva, Beatriz G. Neves, Mariana Magalhães, Célia Cabral, Maria L. S. Cristiano, Patrícia Rijo

“…Methods: Antimicrobial properties of the molecules were evaluated by the well-diffusion method, against Gram-positive bacteria [Staphylococcus aureus American Type Culture Collection (ATCC) 25923, Staphylococcus epidermidis ATCC 12228, Mycobacterium smegmatis ATCC 607], Gram-negative bacteria (Pseudomonas aeruginosa ATCC 27853) and yeast (Saccharomyces cerevisiae ATCC 2601 and Candida albicans ATCC 10231) strains. …”
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