Co-culture of human AT2 cells with fibroblasts reveals a MUC5B phenotype: insights from an organoid model by Yiwen Yao, Felix Ritzmann, Sarah Miethe, Kathrin Kattler-Lackes, Betül Colakoglu, Christian Herr, Andreas Kamyschnikow, Michelle Brand, Holger Garn, Daniela Yildiz, Frank Langer, Robert Bals, Christoph Beisswenger

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Hypobaric hypoxia aggravates neuroinflammation in ligature-induced periodontitis mice via the STAT3 signaling pathway by Lu Chen, Lu Chen, Jiayi Zhang, Xuechao Fei, Jiajing Wang, Jiayue Gao, Xiangpei Yue, Yaqun Jiang, Yaqun Jiang, Zibi Shi, Shaojie Zhang, Xiufang Jiang, Wenyue Chang, Zhonghua Dai, Jianjun Guo, Tong Zhao, Xiaoxia Jiang, Lingling Zhu, Lingling Zhu

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Discovery of benzochalcone derivative as a potential antigastric cancer agent targeting signal transducer and activator of transcription 3 (STAT3) by Jinyun Dong, Jing Yang, Wenkai Yu, Haobin Li, Maohua Cai, Jing-Li Xu, Han-Dong Xu, Yun-Fu Shi, Xiaoqing Guan, Xiang‑Dong Cheng, Jiang‑Jiang Qin

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A critical role for IL-21/IL-21 receptor signaling in isoproterenol-induced cardiac remodeling by Bing Qi, Ruohang Xu, Yanye Jin, Yufei Wang, Tianwei Cheng, Chang Liu, Yujin Ji, Lihong Guo, Jing Li, Yang Gao, Yang Xu, Jianlin Cui, Jie Liu, Zecheng Jiang, Lifeng Feng, Zhi Qi, Liang Yang

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In silico exploration of Elaeocarpus ganitrus extract phytochemicals on STAT3, to assess their anticancer potential by Mehnaj, Abdul Roouf Bhat, Fareeda Athar

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Napabucasin-loaded PLGA nanoparticles trigger anti-HCC immune responses by metabolic reprogramming of tumor-associated macrophages by Zhenwei Song, Hongfei Chen, Xueyao Wang, Zhiyue Zhang, Hui Li, Huajun Zhao, Yang Liu, Qiuju Han, Jian Zhang

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Identification of STAT3 signaling as a shared pathogenic signature in systemic lupus erythematosus, chronic obstructive pulmonary disease, and asthma by Arman Mokaram Doust Delkhah

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Oleanonic acid inhibits glioma growth by inactivating STAT3 via upregulating SIRT6 in nude mice by Jiancun Wang, Yuanyuan Wang, Hui Gao, Qin Sun, Wen Li

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The mitochondrial dysfunction regulated by JAK2/STAT3 pathway leads to the necroptosis in the renal cells under patulin exposure by Yun Liu, Ruhan Yi, Xu Zhang, Xiance Sun, Jing Li, Ningning Wang, Xiaofeng Yao, Cong Zhang, Haoyuan Deng, Shaopeng Wang, Guang Yang

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Naringenin induces ferroptosis in osteosarcoma cells through the STAT3-MGST2 signaling pathway by Yingang Li, Xizhuang Bai

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The scaffold protein DLG4 facilitates RNF63-mediated ubiquitination and degradation of STAT3 in non-small cell lung cancer by Shisong Chen, Hongjie Xu, Ning Li, Yang Yang, Ruxi Pang, Shuwei Zhang, Junjie Qiao, Hao Chen

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Screening of Stat3 inhibitory effects of Korean herbal medicines in the A549 human lung cancer cell line by Jong-Shik Park, Ok-Sun Bang, Jinhee Kim

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A Novel HDAC6 Inhibitor Ameliorates Imiquimod-Induced Psoriasis-Like Inflammation in Mice by Anqi Cao, Yurong Li, Yanqiao Feng, Xiaoquan Wang, Wenyu Wei, Hongyan Sun, Junmin Quan

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Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T‐cell lymphoma by Helena Sorger, Saptaswa Dey, Pablo Augusto Vieyra‐Garcia, Daniel Pölöske, Andrea R Teufelberger, Elvin D de Araujo, Abootaleb Sedighi, Ricarda Graf, Benjamin Spiegl, Isaac Lazzeri, Till Braun, Ines Garces de los Fayos Alonso, Michaela Schlederer, Gerald Timelthaler, Petra Kodajova, Christine Pirker, Marta Surbek, Michael Machtinger, Thomas Graier, Isabella Perchthaler, Yi Pan, Regina Fink‐Puches, Lorenzo Cerroni, Jennifer Ober, Moritz Otte, Jana D Albrecht, Gary Tin, Ayah Abdeldayem, Pimyupa Manaswiyoungkul, Olasunkanmi O Olaoye, Martin L Metzelder, Anna Orlova, Walter Berger, Marion Wobser, Jan P Nicolay, Fiona André, Van Anh Nguyen, Heidi A Neubauer, Roman Fleck, Olaf Merkel, Marco Herling, Ellen Heitzer, Patrick T Gunning, Lukas Kenner, Richard Moriggl, Peter Wolf

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Using siRNA-Based Anti-Inflammatory Lipid Nanoparticles for Gene Regulation in Psoriasis by Zeng A, Liu Y, Wang P, Cao Y, Guo W

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The critical role of signal transducers and activators of transcription-3 in the proliferation of vascular smooth muscle cells by Shuai Li, Chan Liu

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JAK2, STAT3 Gene Polymorphisms in Turkish Patients with Behçet’s Disease by Darya Farhoomand Aksoy, Rahime Aksoy, Sevim Gönen, Ümit Ölmez

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Effect of Statins in the Watch and Wait Phase of Chronic Lymphocytic Leukemia by David E. Spaner

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A first-in-human Phase I trial of the oral p-STAT3 inhibitor WP1066 in patients with recurrent malignant glioma by John de Groot, Martina Ott, Jun Wei, Cynthia Kassab, Dexing Fang, Hinda Najem, Barbara O'Brien, Shiao-Pei Weathers, Carlos Kamiya Matsouka, Nazanin K Majd, Rebecca A Harrison, Gregory N Fuller, Jason T Huse, James P Long, Raymond Sawaya, Ganesh Rao, Tobey J MacDonald, Waldemar Priebe, Michael DeCuypere, Amy B Heimberger

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Co-Inhibition of PARP and STAT3 as a Promising Approach for Triple-Negative Breast Cancer by Changyou Shi, Li Pan, Satomi Amano, Mei-Yi Wu, Chenglong Li, Jiayuh Lin

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