SPARC Levels Modulate the Capacity of Mitomycin to Inhibit the Proliferation of Human Tenon’s Capsule Fibroblasts by Yuanyuan Guo, Shouxiang Ni, Weiyan Zhou, Jiangping Hou, Jiaquan Shen

“…To evaluate the role of SPARC in the antiproliferation effect of MMC on human Tenon’s fibroblasts (HTF). …”
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Elevated Serum Extracellular Vesicle‐Packaged SPARC in Hypertension: A Cross‐Sectional Study in a Middle‐Aged and Elderly Population by Xueying Chen, Han Guo, Xinwei Li, Yang Liu, Xinxin Li, Zhengshuo Cui, Huijuan Ma, Jianxun He, Zhechun Zeng, Huina Zhang

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Fifty years of progress in wildland fire modelling: from empirical to fully physical CFD models by Morvan, Dominique, Accary, Gilbert, Meradji, Sofiane, Frangieh, Nicolas

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STEPNet: A Spatial and Temporal Encoding Pipeline to Handle Temporal Heterogeneity in Climate Modeling Using AI: A Use Case of Sea Ice Forecasting by Sizhe Wang, Wenwen Li, Chia-Yu Hsu

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Astrocyte-Secreted Matricellular Proteins in CNS Remodelling during Development and Disease by Emma V. Jones, David S. Bouvier

“…In this minireview, we discuss the matricellular protein families SPARC (secreted protein acidic and rich in cysteine), Hevin/SC1 (SPARC-like 1), TN-C (Tenascin C), TSP (Thrombospondin), and CCN (CYR61/CTGF/NOV), which are secreted by astrocytes during development. …”
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Association of Glioblastoma Multiforme Stem Cell Characteristics, Differentiation, and Microglia Marker Genes with Patient Survival by Sandra Bien-Möller, Ellen Balz, Susann Herzog, Laura Plantera, Silke Vogelgesang, Kerstin Weitmann, Carolin Seifert, Matthias A. Fink, Sascha Marx, Angela Bialke, Chitra Venugopal, Sheila K. Singh, Wolfgang Hoffmann, Bernhard H. Rauch, Henry W. S. Schroeder

“…At protein level, CD44, ELF4, Nanog, Nestin, and Sparc were elevated in GBM, but only CD133 and Nestin were strongly associated with survival time. …”
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Identification of candidate genes involved in Zika virus-induced reversible paralysis of mice by John D. Morrey, Venkatraman Siddharthan, Hong Wang, Alexandre L. R. Oliveira, Keiichiro Susuki, Rakesh Kaundal, Sara M. Freeman, Aaron J. Thomas, Naveen Duhan, Nathan G. Corry

“…To refine the search for candidate DEGs we used gene ontology analysis and RT-qPCR to select 3 DEGs that could be involved with the node of Ranvier function and 5 DEGs that could be involved with synaptic function. Among these, SparcL1:Sparc DEG ratios were identified to be inversely correlated with ZIKV-induced paralysis, which is consistent with the known function of SPARC protein to antagonize the synaptogenesis of SPARCL1. …”
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Motion Smoothness Analysis of the Gait Cycle, Segmented by Stride and Associated with the Inertial Sensors’ Locations by Leonardo Eliu Anaya-Campos, Luis Pastor Sánchez-Fernández, Ivett Quiñones-Urióstegui

“…Finally, it applies three smoothness metrics (SPARC, PM, and LDLJ) to determine the most reliable metric and the best location for the sensor, using data from 20 healthy subjects who walked an average of 25 steps on a flat surface for this study (117 measurements were processed). …”
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Adipocyte-Specific Fatty Acid-Binding Protein (AFABP) and Chemerin in Association with Gestational Diabetes: A Case-Control Study by Maryam Mosavat, Mitra Mirsanjari, Bashir A. Lwaleed, Maherah Kamarudin, Siti Zawiah Omar

“…However, among these peptides, the role of adipocyte-specific fatty-acid-binding protein (AFABP), chemerin, and secreted protein acidic and rich in cysteine (SPARC) in gestational diabetes (GDM) has not been fully investigated. …”
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Novel transcripts of EMT driving the malignant transformation of oral submucous fibrosis by Smitha Sammith Shetty, Kanaka Sai Ram Padam, Mohit Sharma, Adarsh Kudva, Pratik Patel, Raghu Radhakrishnan

“…The significant roles of MMP9, SPARC, and ITGA5 in fibrosis and malignancy suggest a novel mechanism in which fibrosis-associated type 2 EMT undergoes transition to type 3 EMT, driving OSF towards malignancy.…”
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Effect of Low-Intensity High-Repetition Versus High-Intensity Low-Repetition Elastic Band Resistance Training on Functional Physical Fitness and Myokine Levels in Older Adults by Moon Jin Lee, Jun-Young Sung, Jiyoun Kim

“…SPARC increased significantly only in the HI-LR group (<i>p</i> = 0.021). …”
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Probing late-time annihilations of oscillating asymmetric dark matter via rotation curves of galaxies by Júlia G. Mamprim, Guillermo Gambini, Luan B. Arbeletche, Marcos Olegario, Vitor de Souza

“…We analyzed the effects of the annihilation mechanism in the galaxy rotation curves of the SPARC and LITTLE THINGS catalogs. We searched for the characteristics of the OADM model which best describes the data. …”
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Intellectual property rights vs. public access rights: ethical aspects of the DeCSS decryptation program by Robert Vaagan, Wallace Koehler

“…</b> The DVD-Jon case illustrates that intellectual property rights can conflict with public access rights, as the struggle between proprietary software and public domain software, as well as the SPARC and Open Archives Initiative reflect. <br><b>Results.…”
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Is Pulp Inflammation a Prerequisite for Pulp Healing and Regeneration? by Michel Goldberg, Akram Njeh, Emel Uzunoglu

“…Pulp fibroblasts become odontoblast-like cells producing type I collagen, alkaline phosphatase, and SPARC/osteonectin. Molecules of the SIBLING family, matrix metalloproteinases, and vascular and nerve mediators are also implicated in the formation of a reparative dentinal bridge, osteo/orthodentin closing the pulp exposure. …”
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Changes of plasma cytokines content in Graves’ orbitopathy patients, could be potential markers by Ying Fu, Yuanyuan Zhang, Yaxin An, Bin Cao, Dong Zhao

“…In validation cohort, NORCH3, TBP, α-enolase (ENO1), GPX3, ORM1, extracellular matrix protein-1 (ECM1), SERPINE, IGF1, IGKV1, and SPARC were validated using ELISA kits. We used label-free liquid chromatography–mass spectrometry/MS (LC–MS/MS) quantitative proteomic to analyze plasma cytokines content of Graves’ disease and GO patients. …”
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Transport and profile broadening in the private flux region of ASDEX upgrade and role for power exhaust by D. Brida, G. Grenfell, O. Grover, D. Silvagni, M. Faitsch, U. Stroth, the ASDEX Upgrade Team, the EUROfusion Tokamak Exploitation Team

“…For the tokamaks ITER and SPARC the model predicts PFR widths below 0.3 mm.…”
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Boosting Parallel Applications Performance on Applying DIM Technique in a Multiprocessing Environment by Mateus B. Rutzig, Antonio C. S. Beck, Felipe Madruga, Marco A. Alves, Henrique C. Freitas, Nicolas Maillard, Philippe O. A. Navaux, Luigi Carro

“…We have successfully coupled a dynamic reconfigurable system to an SPARC-based multiprocessor and obtained performance gains of up to 40%, even for applications that show a great level of parallelism at thread level.…”
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Safety, Tolerability and Pharmacokinetic-Pharmacodynamic Relationship of NX210c Peptide in Healthy Elderly Volunteers: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascend... by Annette Janus, Daniël Dumas, Juliette Le Douce, Sébastien Marie, Giuseppe Pasculli, Pauline Bambury, Sighild Lemarchant, Philip Kremer, Yann Godfrin

“…In silico data modelling revealed salient pharmacokinetic-pharmacodynamic relationships, including reduction of claudin-5, neurofilament light chain, and SPARC-like protein 1 release, and degradation of homocysteine. …”
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Single-cell transcriptomics reveals novel chondrocyte and osteoblast subtypes and their role in knee osteoarthritis pathogenesis by Yuan Liu, Wacili Da, Ming-Jie Xu, Chao-Xin Xiao, Tao Deng, Sheng-Liang Zhou, Xiao-Ting Chen, Yao-Jia Zhou, Li Tang, Yong Nie, Yi Zeng, Hui-Qi Xie, Bin Shen

“…The number of H-type vessels was increased in the subchondral bone, recruiting osteoprogenitor cells and facilitating osteogenesis in KOA mice. Sparc + osteoblasts have negatively regulated bone mineralization and osteoblastic differentiation, aggravated the pathological remodeling of subchondral bone, and promoted the progression of KOA. …”
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Molecular Mechanism of Local Drug Delivery with Paclitaxel-Eluting Membranes in Biliary and Pancreatic Cancer: New Application for an Old Drug by Sookhee Bang, Sung Ill Jang, Su Yeon Lee, Yi-Yong Baek, Jieun Yun, Soo Jin Oh, Chang Woo Lee, Eun Ae Jo, Kun Na, Sugeun Yang, Don Haeng Lee, Dong Ki Lee

“…Moreover, implantation of the PEM inhibited tumor-stromal interaction-related expression of proteins such as CD44, SPARC, matrix metalloproteinase-2, and vimentin. …”
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