Petrogenesis of REE-rich two-mica granite from the Indosinian Xiekeng pluton in South China Block with implications for REE metallogenesis by Defu Zhang, Defu Zhang, Tingting Lv, Xiangaung Wang, Xiangaung Wang, Mingxuan Cao, Xiquan Chen, Xiquan Chen, Yongwen Zhang, Liangxin Gong

“…The rock features high contents of SiO2 (71.3–77.73 wt%), K2O (4.42–5.62 wt%), K2O/Na2O (1.36–1.87), and with an A/CNK value of 1.11–1.27, a differentiation index (DI) of 90.28–94.47, zircon saturation temperatures of 780°C–806°C, and K/Rb, Nb/Ta, and Zr/Hf ratios of 8.40–11.04, 2.38–9.24, and 25.42–35.37, respectively. …”
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Complicaciones maternas, fetales y neonatales en Embarazadas con enfermedades Autoinmunitarias sistémicas, y su seguimiento con flujometría Doppler. by Yoel Cardet Niebla, Juan Carlos Ojeda Blanco, Yosdaily Guerra Aroche, Flabia Toledo Mederos

“…Se empleó las pruebas estadísticas de homogeneidad de chi cuadrado (X 2); se fijó un nivel de confiabilidad del 95 %, para el cual, si la significación estadística del estadígrafo X 2 fue menor que 0,05, entonces se rechazó la hipótesis nula y considero hubo diferencias significativas Resultados: El Lupus eritematoso sistémico fue la enfermedad autoinmune más frecuente con un 74%, dentro de las complicaciones maternas fetales, la restricción fetal con 34 casos, la preeclampsia con 43 casos y el parto pretérmino con 27 casos y las mismas se presentaron en más del 60% de pacientes con lupus. …”
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Antecedentes da definição do design do sistema de controle gerencial: evidências empíricas nas empresas brasileiras by Fábio Frezatti, Emanuel Junqueira, Diógenes de Souza Bido, Artur Roberto do Nascimento, Tânia Regina Sordi Relvas

“…Esses atributos definem, limitam e expandem o poder de atuação do controle gerencial (BERRY; BROADBENT; OTLEY, 2005) das organizações, e eles são interdependentes entre si, na medida em que um influencia o outro. Eles se constituem a base a partir da qual o modelo de gestão da organização é estruturado e desenvolvido. …”
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Evaluating GEMS HCHO Retrievals With TROPOMI Product, Pandora Observations, and GEOS‐Chem Simulations by Weitao Fu, Lei Zhu, Hyeong‐Ahn Kwon, Rokjin J. Park, Gitaek T. Lee, Isabelle DeSmedt, Song Liu, Xicheng Li, Yuyang Chen, Dongchuan Pu, Juan Li, Xiaoxing Zuo, Peng Zhang, Yali Li, Zhuoxian Yan, Xue Zhang, Jiaming Zhang, Xingyi Wu, Huizhong Shen, Jianhuai Ye, Chen Wang, Tzung‐May Fu, Xin Yang

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红景天苷通过抑制TLR4/NF-κB通路抑制高磷诱导的血管平滑肌细胞钙化 by 刘芳, 李明熹, 颜建云

“…方法本研究采用人血管平滑肌细胞钙化模型，用不同浓度的红景天苷处理细胞，茜素红染色及钙离子浓度定量检测细胞钙化，Western blot检测红景天苷对成骨样分化蛋白Runt相关转录因子2（RUNX2）和骨形态发生蛋白2（BMP2）的影响；检测红景天苷对Toll样受体4（TLR4）、核因子κB p65（NF-κB p65）和磷酸化的核因子κB p65（p-NF-κB p65）的影响；检测红景天苷对白细胞介素6（IL-6）、白细胞介素1β（IL-1β）的影响。采用TLR4 小干扰RNA（si-TLR4）处理血管平滑肌细胞，研究TLR4介导红景天苷对平滑肌细胞钙化的抑制作用。结果茜素红染色及钙离子浓度定量结果提示不同浓度的红景天苷改善高磷诱导的人血管平滑肌细胞的钙化（<italic>P</italic>&lt;0.05）。…”
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A Model H5N2 Vaccine Strain for Dual Protection Against H5N1 and H9N2 Avian Influenza Viruses by Jin-Ha Song, Seung-Eun Son, Ho-Won Kim, Se-Hee An, Chung-Young Lee, Hyuk-Joon Kwon, Kang-Seuk Choi

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Estructura genética de poblaciones de Phytophthora capsici en el noreste de la provincia de Buenos Aires, Argentina by M.J. Iribarren, C. Borassi, A. Ferri, B González, M. Steciow, E. Guillín

“…La razón de TAs varía entre regiones geográficas y por lo tanto también la chance para reproducirse sexualmente. Si se toma en cuenta que la durabilidad de las medidas de control depende de la variación genética, es aconsejable considerar la cantidad y la distribución de variación genética dentro y entre poblaciones de especies, es decir, la estructura genética. …”
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Amélioration des conditions de vie de lémuriens issus du commerce illégal et ayant subi différents traumatismes à Madagascar by Emeline Lempereur, Delphine Roullet, Emmanuelle Pouydebat

“…Le second objectif visait à déterminer si l’histoire des individus avait un impact sur l’expression de leurs comportements en l’absence ou présence d’enrichissements. …”
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MiR- 146b-5p inhibits Candida albicans-induced inflammatory response through targeting HMGB1 in mouse primary peritoneal macrophages by Jing Cheng, Xiaoxing Tian, Chuanxin Wu, Jiaojiao Wang, Huiling Liu, Sha Cheng, Hang Sun

“…The nuclear and cytoplasm translocation of HMGB1 and NF-κB p65 were detected by Western blot and laser confocal microscopy. After siHMGB1 transfection, the expression levels of HMGB1, inflammatory mediators, p-IKK, IKK, p-IκBα, IκBα and NF-κB p65 were assessed using Western blot, qRT-PCR and ELISA. …”
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Valerenic acid attenuates pathological myocardial hypertrophy by promoting the utilization of multiple substrates in the mitochondrial energy metabolism by Tiantian Liu, Xu Chen, Qianbin Sun, Junjun Li, Qiyan Wang, Peng Wei, Wei Wang, Chun Li, Yong Wang

“…Methods: The efficacy of VA on PMH was confirmed by in vivo and in vitro experiments and the underlying mechanism was investigated by molecular dynamics (MD) simulations and specific siRNA interference. Results: VA enhanced cardiomyocyte fatty acid oxidation (FAO), inhibited hyper-activated glycolysis, and improved the unbalanced pyruvate-lactate axis. …”
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USP22 inhibits microglial M1 polarization by regulating the PU.1/NLRP3 inflammasome pathway by Ming-chen Yu, Xiao-lin Li, Ming-liang Ning, Zhen-zhong Yan, Wan-tao Yu

“…Methods: The BV-2 mouse microglia line was cultured in vitro, and plasmid and siRNA transfection was performed to overexpress or knockdown USP22. …”
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Carnívoros en el sudoeste de la provincia de Buenos Aires: ecología y conflictos con los ganaderos by N. CARUSO, E.M. LUENGOS VIDAL, M. LUCHERINI, M. GUERISOLI, S. MARTINEZ, E.B. CASANAVE

“…Los participantes de los talleres identificaron un posible aumento de los conflictos relacionado con la disminución de personas en los campos. Si bien la caza ilegal de algunas especies es la respuesta más común, los productores demostraron interés y voluntad de aplicar medidas de mitigación. …”
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SLC1A5 is a key regulator of glutamine metabolism and a prognostic marker for aggressive luminal breast cancer by Lutfi H. Alfarsi, Rokaya El Ansari, Busra Erkan, Ali Fakroun, Madeleine L. Craze, Mohammed A. Aleskandarany, Kiu Wai Cheng, Ian O. Ellis, Emad A. Rakha, Andrew R. Green

“…Furthermore, SLC1A5 knockdown by siRNA or GPNA inhibition significantly reduced cell proliferation and glutamine uptake in ZR-75-1 cells. …”
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Sustainable healthy settlement on a small island as a cultural heritage area by I. Martias, R. Rifardi, A. Agrina, I. Suprayogi

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New insight into the role of the pathway NLRP1 and NLRP3 inflammasomes and IL-33 in ultraviolet-induced cutaneous carcinogenesis by Aleksandra Lesiak, Aleksandra Lesiak, Karolina Wodz, Justyna Ceryn, Dorota Sobolewska-Sztychny, Dorota Sobolewska-Sztychny, Igor Bednarski, Janusz Piekarski, Marta Pabianek, Dariusz Nejc, Izabela Dróżdż, Joanna Narbutt, Marcin Noweta, Magdalena Ciążyńska, Magdalena Ciążyńska

“…To inhibit the expression of NLRP1 and NLRP3 genes, cells were transfected with targeted siRNAs. Gene expression of inflammasome components and effector proteins was quantified using Real-time PCR and ELISA.ResultsThere was a marked upregulation in the expression levels of cytokine genes IL-18, IL-1β, and IL-33 upon exposure to UVB and UVA radiation, compared to non-irradiated keratinocytes. …”
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The role of nutrient availability and resorption efficiency and their impact on nutrient conservation in mangroves by M.E.B. Gerona-Daga, R.A. MacKenzie, L.G. Sumabat-Dacones, C.F.P. Naputo, S.G. Salmo III

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Characteristics of the monkeypox virus isolate obtained from the first patient in Russia and its sensitivity to 7-[N-(4-trifluoromethylbenzoyl)-hydrazinocarbonyl]-tricyclo-[3.2.2.0... by Alena S. Ovchinnikova, Dmitrii A. Odnoshevsky, Alexey S. Kabanov, Sergey A. Bodnev, Oleg V. Pyankov, Oksana P. Os'kina, Maria V. Sivay, Andrey V. Bespalov, Tatyana V. Tregubchak, Larisa N. Shishkina, Oleg S. Taranov, Vladimir V. Zolin, Artemiy A. Sergeev, Alexander P. Agafonov

“…The effectiveness of the finished dosage form of NIOCH-14 against the new strain of MPXV based on the results of determining the 50% virus inhibitory concentration (IC50) was 0.02 μg/mL, and the selectivity index (SI) was 15,000. Conclusion. In this study, the pathogen of monkeypox was detected and identified using real-time PCR, NGS and electron microscopy, and the first imported case of this disease in Russia was confirmed. …”
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Implantable Multifunctional Micro‐Oxygen Reservoir System for Promoting Vascular‐Osteogenesis via Remodeling Regenerative Microenvironment by Min Rui, Jiannan Mao, Hongshuai Wu, Yujian Hui, Hao Shen, Yilin Yang, Tao Ma, Kewei Ren, Juan Wang, Wenguo Cui, Qin Shi, Huilin Yang

“…Therefore, to explore a strategy and its intrinsic mechanism for supplying oxygen locally and remodeling the regenerative microenvironment, an innovative oxygenating hydrogel microsphere system with sustained oxygenation and antioxidant properties is introduced by loading CaO2@SiO2@PDA (CSP) nanoparticles. Specifically, the CSP nanoparticles exhibited broad‐spectrum free radicals scavenging ability, along with prolonged controlled‐release of oxygen once integrated into the gelatin methacrylate anhydride (GelMA) microspheres (CSP‐GM). …”
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1º WORKSHOP FCNYM/CONICET: “REALIDADES Y DESAFÍOS EN EL ABORDAJE INTEGRAL DE LA SALUD” by Sandra Torrusio, María Florencia Cesani Rossi, Pablo Demetrio, Laura Teves, Lorena Zonta, Sergio Rodríguez Gil, Gisel Padula

“…En ese espacio, representantes de los diferentes sectores (académico-científico, privado, emprendedor, público) presentaron sus experiencias y vivencias, destacando y coincidiendo en la necesidad de vincularse entre sí, identificando problemáticas comunes, oportunidades y planteando soluciones más integradoras y participativas. …”
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Percepción ética de la marca y valor de marca by Montserrat Barba Rey, Alicia Blanco - González, Giorgia Miotto

“…Objetivo: El objetivo de este estudio es analizar si las marcas percibidas como éticas son, a la vez, las que tienen mejores resultados económicos y un mejor valor de marca. …”
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