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9141
The injury effect of osteopontin in sepsis-associated lung injury
Published 2025-01-01“…Mechanistic investigations in MH-s cells revealed that OPN-siRNA suppressed the LPS-induced macrophage inflammatory response by inhibiting caspase1-dependent classical pyroptosis signaling pathway. …”
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9142
Fertilización nitrogenada en Festuca arundinacea Schreb. para producción de semilla con riego en el norte de Buenos Aires, Argentina
Published 2014-01-01“…Con la tecnología empleada en este experimento, sin N, se lograron rendimientos de semilla pura de ≈ 600 kg.ha-1, que fueron elevados por el agregado de N hasta 66%. Si se mantiene la relación histórica entre el precio de la semilla y el costo del nitrógeno, la fertilización con N es una práctica rentable.…”
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9143
过表达整合素链接激酶通过NF-kB通路促进脑胶质瘤细胞的上皮间质转化
Published 2016-01-01“…当分别用NF-kB特异性阻断剂BAY11-7028及p65 siRNA的方法阻断该通路后,稳定转染组中E-cadherin蛋白表达明显升高?【结论】 胶质瘤中过表达ILK可使侵袭能力增强,同时可下调E-cadherin,上调vimentin及Snail,Slug,Twist的表达,可能通过此机制促进脑胶质瘤细胞的上皮间质转化,NF-kB通路可能参与?…”
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9144
La photogrammétrie subaquatique pour l’étude des habitats en cours d’eau
Published 2025-02-01“…Les résultats obtenus par photogrammétrie permettent une caractérisation millimétrique des variations de surface du substrat et apportent des éléments supplémentaires pour la compréhension de l’écologie des juvéniles de lamproie. Si des pistes d’amélioration peuvent être apportées, la photogrammétrie subaquatique est une technique prometteuse pour l’étude des habitats dans un contexte de forte anthropisation des cours d’eau. …”
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9145
ANÁLISIS EMERGÉTICO DE LA PRODUCCIÓN DE ÁRIDOS EN CUBA. CASO DE ESTUDIO: FÁBRICA EL CANAL
Published 2024-10-01“…Resultados y Discusión: El proceso de producción de la fábrica El Canal puede ser mejorado mediante diferentes cambios tecnológicos, siendo el más adecuado la introducción de plantas de hidrociclones en el proceso de clasificación, dado que mitiga impactos ambientales con una considerable menor inversión emergética. Conclusiones: Si bien el proceso de producción de áridos tiene un impacto económico moderado, este no es sostenible a largo plazo (ESI=0,0011) ya que incurre en marcados impactos ambientales debido al uso intensivo de recursos no renovables.…”
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9146
Repressor Element 1 Silencing Transcription Factor (REST) Governs Microglia-Like BV2 Cell Migration via Progranulin (PGRN)
Published 2020-01-01“…Small interfering RNA (siRNA) targeting progranulin (PGRN) were delivered into BV2 cells, and results showed that PGRN functions to promote BV2 migration. …”
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9147
Vinblastine resets tumor-associated macrophages toward M1 phenotype and promotes antitumor immune response
Published 2023-08-01“…RNA-seq of TAM of treated and untreated with VBL was performed to explore the changes in pathway activities. siRNA mediated knockdown experiments were performed to verify the target pathway that was affected by VBL treatment.Results Here, we showed that VBL, an antineoplastic agent that destabilizes microtubule, drove macrophage polarization into the M1-like phenotype both in vitro and in tumor models. …”
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9148
Nr5a2 promotes cancer stem cell properties and tumorigenesis in nonsmall cell lung cancer by regulating Nanog
Published 2019-03-01“…Using the LLC‐SD model, through transient and stable siRNA interference of Nr5a2 expression, we provided convincing evidence for a regulatory role of Nr5a2 in the maintenance of lung CSC self‐renewal and stem cell properties in vitro. …”
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9149
Lotus tenuis (Waldst. et Kit), estudio para un manejo con múltiples propósitos
Published 2020-01-01“…El caso AF permite dos opciones, por un lado, obtener el forraje del corte (322,33 g MS/m²) y semillas en la cosecha (48,15 g MS/m²). Por otro lado, si se considera solamente la producción de semillas, es posible obtener las del corte (40,92 g MS/m²) que, sumadas a las de la cosecha, darían un rendimiento de 89,07 g MS/m². …”
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9150
Antiplasmodial and Cytotoxic Activities of Extracts of Selected Medicinal Plants Used to Treat Malaria in Embu County, Kenya
Published 2020-01-01“…In this study, aqueous extracts of T. brownii and S. africana demonstrated high antiplasmodial activity and high selectivity indices values (SI≥10) and were found to be safe. It was concluded that T. brownii and S. africana aqueous extracts were potent antiplasmodial agents. …”
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9151
Kaempferol protects against high-salt-induced hypertension and vascular endothelial injury by inhibiting ferroptosis through the ATF4/ACSL4 pathway
Published 2025-02-01“…Additionally, human aortic endothelial cells (HAECs) cultured under high-salt conditions were used to assess Kae's protective effects, with ATF4 and acyl-CoA synthetase long-chain family member 4 (ACSL4) knocked down via siRNA transfection. Our results showed that Kae significantly reduced high-salt-induced hypertension, improved vascular endothelial dysfunction, inhibited ferroptosis, and suppressed ATF4 expression. …”
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9152
Identification and Characterization of Genes Associated with Intestinal Ischemia-Reperfusion Injury and Oxidative Stress: A Bioinformatics and Experimental Approach Integrating Hig...
Published 2025-01-01“…A mouse IIRI model and ROC curve were employed to verify the accuracy of HIOSRGs. Finally, siRNA was utilized to suppress the expression of HDAC3 in Caco2 cells, and the changes in oxidative stress levels before and after hypoxia-reoxygenation in Caco2 cells were observed.Results: A total of 277 OSRGs and 4 HIOSRGs were obtained. …”
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9153
ORGANISING A «SERATA ITALIANA»: A PROJECT-BASED LEARNING EXPERIENCE WITH FLEMISH STUDENTS OF L2 ITALIAN
Published 2025-01-01“…Organizzare una “Serata italiana”: un’esperienza di apprendimento basato su progetto con studenti fiamminghi di italiano L2 Questo articolo presenta i risultati di uno studio qualitativo che analizza punti di forza e debolezze di un innovativo approccio di apprendimento basato su progetto (project based learning: PBL) per l’acquisizione dell’italiano L2, incentrato sull’organizzazione di un evento culturale. I risultati si basano su un’esperienza quinquennale con studenti universitari fiamminghi iscritti al corso di Comunicazione Pubblica e Aziendale in italiano presso l’Università di Gand (Belgio). …”
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9154
Class III β-Tubulin Overexpression Induces Chemoresistance to Eribulin in a Leiomyosarcoma Cell Line
Published 2018-01-01“…We found that class III β-tubulin (TUBB3) was overexpressed in the resistant cell line, and siRNA knockdown of TUBB3 partially recovered sensitivity to eribulin. …”
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9155
Congreso latinoamericano de educación de residentes: LACRE 2023 (virtual).
Published 2025-01-01“…La pandemia de COVID-19, si bien forzó el formato virtual del congreso, fue aprovechada como una oportunidad para generar aprendizajes que transformaron las prácticas formativas, haciéndolas más creativas y eficientes. …”
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9156
整合素β4调控脑血管发育
Published 2022-09-01“…使用小干扰RNA(small interfering RNA, siRNA)在永生化人脑微血管内皮细胞(hCMEC/D3)中敲低<italic>ITGB4</italic>,用蛋白免疫印迹(WB)检测其敲低效果。…”
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9157
Movilización ciudadana frente al proyecto de la “Autopista Urbana Oriente” en la Ciudad de México
Published 2024-06-01“…Asimismo, a los ciudadanos afectados se les ha negado el derecho a la consulta y, en consecuencia, han protestado y se han movilizado. No obstante, si bien estos han recurrido a instancias legales, se ha permitido la vulnerabilidad de sus derechos ciudadanos. …”
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9158
El tratamiento trombofiláctico no afecta los niveles de hemoglobina y hematocrito luego de una artroplastia total de cadera
Published 2024-10-01“…El objetivo principal de este estudio fue evaluar la prevalencia de anemia posoperatoria en pacientes sometidos a una ATC programada y determinar si está relacionada con el tratamiento tromboprofiláctico administrado. …”
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9159
Espacios verdes espontáneos. Análisis de factores que promueven su surgimiento
Published 2023-11-01“…Como objetivo secundario se analizó si la Pandemia de COVID-19 fue decisiva en la elección de estos lugares. …”
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9160
Avusturya Kamuoyunda Bosna-Hersek’in İşgali: Biat ile Direniş Arasında Bosna-Hersek Müslümanları 1878-1879
Published 2025-01-01“…Müslüman, Katolik ve Ortodoks nüfusuyla kozmopolit bir yapıya sahip olan Osmanlı Vilayeti Bosna-Hersek, jeopolitik konumu ile de Osmanlı Monarşisi, Avusturya-Macaristan Monarşisi ve Çarlık Rusya’sı arasında Balkanlar’daki nüfuz mücadelesine sahne olmuştur. …”
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