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  1. 6521
  2. 6522

    Enhanced expression of ten‐eleven translocation 1 reverses gemcitabine resistance in cholangiocarcinoma accompanied by a reduction in P‐glycoprotein expression by Chuanxu Wang, Hua Ye, Lei Zhang, Yayu Cheng, Shifeng Xu, Ping Zhang, Zijie Zhang, Jimin Bai, Fangkang Meng, Lin Zhong, Guangjun Shi, Hao Li

    Published 2019-03-01
    “…After transfecting the gemcitabine‐resistant CCA cell lines with TET1 gene or siRNA, the cell viability test was obtained to verify the effect of TET1 on the sensitivity of CCA cells to gemcitabine. …”
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  3. 6523

    Estudio volumétrico de las canteras romanas de Rodadero de los Lobos – cortijo Piquín (sierra de Córdoba) mediante UAV LiDAR by Juan Carlos Moreno Escribano, Antonio Monterroso Checa, Massimo Gasparini, María Luisa Loza Azuaga, Esther Ontiveros Ortega, José Beltrán Fortes, Daniel Becerra Fernández

    Published 2025-01-01
    “…No obstante, y a pesar de la importancia que tuvo la explotación y el uso de las rocas ornamentales del sector de Ossa-Morena, hasta el momento había sido muy irrisoria la investigación sobre la explotación de canteras en época antigua en la Sierra de Córdoba, debido, fundamentalmente, a la inaccesibilidad orográfica. Por tanto, si se compara con Sevilla, Málaga y Huelva, provincias con amplios estudios por no existir este problema de accesibilidad, este trabajo cobra una gran importancia.…”
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  4. 6524

    Myofibrillogenesis Regulator-1 in Smooth Muscle Cells Modulates Inflammation Signaling Pathways via Regulating ROCK1 Ubiquitination and Degradation to Impact Aortic Dissection by Yin H, Li X, Lu D, Zhao X, Yang Z, Wang Z, Xu F, Chen Y, Li C

    Published 2025-02-01
    “…In vitro experiments, human aortic smooth muscle cells were extracted, and an in vitro dissection model was constructed with angiotensin II. siRNA silencing studies were performed to investigate the effects of MR-1 and ROCK1 on the development of AD and their interconnections.Results: Analysis of aortic tissues revealed significantly elevated levels of MR-1 and ROCK1 in AD patients, and meanwhile the inflammatory indexes showed the same trend. …”
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  5. 6525

    Perception des asymétries oro-faciales par jugement humain de visages chimériques de babouin lors d'expression d'émotion by Catherine Wallez, Jacques Vauclair

    Published 2014-01-01
    “…Un participant humain doit juger de l’intensité émotionnelle entre un visage chimérique gauche/gauche et un visage chimérique droit/droit. Si le visage gauche/gauche est préféré, cela indique une spécialisation de l’hémisphère droit dans l’expression des émotions. …”
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  6. 6526

    Phase Transitions and Structural Evolution of Manganese Ores During High-Temperature Treatment by Ruslan Z. Safarov, Yerlan A. Baikenov, Assemgul K. Zhandildenova, Eldar E. Kopishev, Ruslan M. Kamatov, Jumat B. Kargin, H. Sanchez Cornejo, Crispin H. W. Barnes, Luis De Los Santos Valladares

    Published 2025-01-01
    “…Conversely, the Zhaksy ore samples displayed a sharp increase in braunite-phase (Mn<sub>7</sub>O<sub>12</sub>Si) content, reaching 83.81% at 1100 °C, alongside significant quartz amorphization. …”
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  7. 6527

    TMEM135 deficiency improves hepatic steatosis by suppressing CD36 in a SIRT1-dependent manner by Arun Chhetri, Channy Park, Hyunsoo Kim, Laxman Manandhar, Chagtsalmaa Chuluunbaatar, Jaetaek Hwang, Xiaofan Wei, Gyuho Jang, Batching Chinbold, Hyug Moo Kwon, Sang-wook Lee, Raekil Park

    Published 2025-02-01
    “…However, inhibition of SIRT1 in TMEM135-depleted cells using siSIRT1 or the SIRT1 inhibitor EX-527 resulted in an increase of CD36 expression and consequent TG levels. …”
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  8. 6528

    EFECTO DEL CONSUMO DE CREATINA SOBRE LA EJECUCIÓN DE DESTREZAS REALIZADAS EN FORMA INTERMITENTE Y DE DURACIÓN PROLONGADA by Óscar Pablo Gutiérrez Sancho, José Moncada Jiménez, Wálter Salazar Rojas

    Published 2002-06-01
    “…El análisis de seguimiento para la interacción de ciclismo reveló que todas lascondiciones fueron diferentes entre (p &lt; 0.05), y que éstas diferencias en los promedios se encontraban enlos intervalos 1, 2 y 4. …”
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  9. 6529
  10. 6530
  11. 6531

    Planificación del desarrollo en Argentina. Una agenda de avances y desafíos abiertos (2003-2015) by Ariel Oscar García

    Published 2016-12-01
    “…Parecieran haber surgido más por situaciones circunstanciales que producto de una planificación estatal, situación que discute el hecho de si la inspiración estatal en su conjunto ha sido neo-estructuralista o más básicamente orientada al fomento de la demanda agregada. …”
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  12. 6532
  13. 6533

    Cytotoxicity Potential of Endophytic Fungi Extracts from Terminalia catappa against Human Cervical Cancer Cells by Michèle Stella Majoumouo, Marius Belmondo Tincho, Rufin Marie Kouipou Toghueo, Thureyah Morris, Donavon Charles Hiss, Fabrice Fekam Boyom, Chitra Mandal

    Published 2020-01-01
    “…A 50% cytotoxic concentration (CC50) of 268.4 µg/ml was obtained with HFF cells and the selectivity index (SI) was 8.01. The percentages of cell populations were increased at late apoptosis (Annexin+/PI+), with the percentages of 27.4 ± 0.3 and 19.2 ± 0.01 obtained, respectively, for 50 µg/ml and 80 µg/ml of the N97 extract and 2.1 ± 0.1 obtained for the control in late apoptosis (Annexin V+/PI+) . …”
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  14. 6534
  15. 6535

    Medición de la compensación del riesgo en el mercado de criptomonedas - Measuring risk compensation in the cryptocurrency market by Andrés Caicedo Carrero, Jorge Alexander Cortés Cortés, Wilmar Arnulfo Bravo Murillo, Myriam Aydee Moreno Garzón

    Published 2025-01-01
    “…Introducción/objetivo: este estudio analiza el rendimiento ajustado al riesgo de las criptomonedas más populares en comparación con el índice S&P 500, utilizando el Alpha de Jensen para evaluar si estas superan el rendimiento ajustado por riesgo en el periodo 2019-2023. …”
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  16. 6536

    Artificial intelligence analysis of thermal energy for convectively heated ternary nanofluid flow in radiated channel considering viscous dissipations aspects by Hamid Qureshi, Amjad Ali Pasha, Muhammad Asif Zahoor Raja, Zahoor Shah, Salem Algarni, Talal Alqahtani, Waqar Azeem Khan, Moinul Haq

    Published 2025-02-01
    “…This research works to establish the convective heat transfer coefficient (CHTC) of new improved ternary hybrid functionalized nanofluids with CuO, Fe2O3, and SiO2 nanoparticles in polymeric fluid. The investigations are aimed at the use of the state-of-the-art AI techniques for predicting and simulating the heat transfer processes in radiated channels as well as incorporating the effects of viscous dissipation and radiation. …”
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  17. 6537

    Regulation of human papillomavirus E6 oncoprotein function via a novel ubiquitin ligase FBXO4 by Arushi Vats, Luca Braga, Nezka Kavcic, Paola Massimi, Edoardo Schneider, Mauro Giacca, Laimonis A. Laimins, Lawrence Banks

    Published 2025-02-01
    “…Therefore, to identify these novel ubiquitin ligases, we performed high-throughput human siRNA library screen against ubiquitin ligases in clustered regularly interspaced palindromic repeat (CRISPR)-edited E6AP-knockout human embryonic kidney (HEK) 293 cells, stably expressing green fluorescent protein (GFP)-tagged HPV-18E6. …”
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  18. 6538

    Recherche d’alcaloïdes dans les plantes consommées par Pan paniscus et celles utilisées pour le traitement des maladies gastro-intestinales par Homo sapiens à LuiKotale (Parc Natio... by Gaby Kitengie Matshimba, Barbara Fruth, Nono Bondjengo Ikombe, Dieudonné Musibono, Constantin Lubini, Gottfried Hohmann

    Published 2014-01-01
    “…De l’analyse de 350 plantes échantillonnées (correspondant à 6300 tests) soit 97% sur 360 prévues initialement, la présence d’alcaloïdes a été avérée dans 48 espèces (de l’ordre de 80%) correspondant à 24 familles indépendamment de leur teneur et du nombre d’individus retenus pour l’analyse. Si pour quelques espèces, l’absence ou la teneur en alcaloïdes était quasi-constante, le plus grand nombre a présenté une remarquable diversité intra et interspécifique en teneur d’alcaloïdes avec une forte concentration dans les racines. …”
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  19. 6539
  20. 6540

    Exploring the Mechanisms of Iron Overload-Induced Liver Injury in Rats Based on Transcriptomics and Proteomics by Yujia Shu, Xuanfu Wu, Dongxu Zhang, Shuxia Jiang, Wenqiang Ma

    Published 2025-01-01
    “…Using the agonist of HO-1 agonist cobalt protoporphyrin (CoPP) to induce HO-1 overexpression can significantly alleviate the decrease in FAC-induced BRL-3A cell viability (<i>p</i> < 0.01), ROS (<i>p</i> < 0.01), and lipid ROS (<i>p</i> < 0.01). In addition, siLnc286.2 treatment can increase HO-1 expression, alleviate the decline of FAC-induced BRL-3A cell activity, and increase lipid ROS (<i>p</i> < 0.05) content. …”
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