The Role of Therapeutic Anticoagulation in COVID-19 by Ruth McGovern, Patrick Conway, Isabell Pekrul, Omar Tujjar

“…Coagulopathy has proven to be a common complication of the novel coronavirus SARS-CoV-2, with evidence of elevated D-dimers and fibrin degradation products associated with an increased incidence of thromboembolism. …”
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Massive Pulmonary Embolism Complicating Coronavirus Disease 2019 (COVID-19) Pneumonia: A Case Report by Shruti Hegde, Gemini Yesodharan, John Tedrow, Alena Goldman

“…His swab turned positive for SARS-CoV-2 infection on real-time reverse transcriptase-polymerase chain reaction assay (RT-PCR) on day 2 of his ED visit. …”
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Chordoma Spontaneous Regression After COVID-19 by Luis Fernando Moura da Silva Junior, Gyl Eanes Barros Silva, Marcos Adriano Garcia Campos, Antonio Augusto Lima Teixeira Júnior, Ramon Moura Santos, Orlando José dos Santos, Natalino Salgado Filho

“…Further studies are encouraged in order to gain a better understanding of the SARS-CoV-2–chordoma interaction.…”
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Linfoma en pacientes con enfermedad reumática y COVID-19 recidivante by Urbano Solis Cartas, Jorge Luis Valdés González, Wilmar Hernández Perdomo, Washington Patricio Vásconez Andrade

“…Caso clínico: Se presentan 2 pacientes con diagnóstico de enfermedades reumáticas que tuvieron infecciones por SARS-CoV-2 en 3 ocasiones cada uno. Un año después del último cuadro respiratorio comenzaron con manifestaciones clínicas que permiten llegar al diagnóstico de linfoma de Hodgkin, en un paciente masculino, de 27 años de edad con artritis reumatoide y linfoma no Hodgkin y una paciente femenina, de 58 años de edad con antecedentes de artritis reumatoide y síndrome de Sjögren. …”
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La migración de retorno a México en tiempos de Donald Trump: Reflexiones sobre el acceso a una universidad pública mexicana by Axel Manuel Navarro Hernández, Carlos Alberto Garrido de la Calleja, Óscar Misael Hernández Hernández

“…A partir de los registros de 174 datos, en dichas solicitudes se identifica diferencias en las características de los aspirantes (sexo, edad, parentesco del responsable y tiempo en el extranjero) en dos momentos específicos: la toma presidencial de Donald Trump y el año de restricciones por la pandemia por sars-cov-2. El conocimiento de estas condiciones facilita acciones congruentes para el aprovechamiento de los migrantes de retorno en las dependencias educativas de nivel superior; sin embargo, para lograr ese propósito se requiere examinar las concordancias y diferencias de estos hallazgos con otras instituciones de educación superior interesadas en los flujos migratorios de retorno a México.…”
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Severe outcomes among adults with TB during COVID-19 by T. Jacobs, E. Morden, M. Smith, A. von Delft, R. Kassanjee, V. Mudaly, A. Boulle, M-A. Davies

“…BACKGROUND: The COVID-19 pandemic prompted strict public health measures to reduce SARS-CoV-2 transmission, potentially interrupting TB programmes in the Western Cape, South Africa. …”
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Prevalence and correlates of burn-out among Nigerian medical doctors during the COVID-19 pandemic: a cross-sectional study by Ruth Eshikotse Pius, Janet Ngozi Ajuluchukwu, Alero Ann Roberts

“…Medical personnel have faced several clinical and non-clinical challenges because of the novel coronavirus (SARS-CoV-2) pandemic, which predisposes them to burn-out. …”
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COVID-19 Vaccine Booster Dose Fails to Enhance Antibody Response to Omicron Variant in Reinfected Healthcare Workers by Leire Fernández-Ciriza, Álvaro González, José Luis del Pozo, Alejandro Fernandez-Montero, Francisco Carmona-Torre, Paula Martínez de Aguirre, María del Mar Sarasa, Silvia Carlos, Gabriel Reina

“…The emergence of new variants and diverse vaccination regimens have raised uncertainty about vaccine effectiveness against SARS-CoV-2. This study aims to investigate the impact of Omicron primo-/reinfection and primary vaccination schedules on the immunogenicity of an mRNA-based booster dose over a six-month period. …”
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Características y correlación entre distancia recorrida y la fuerza de agarre manual en peruanos que padecieron COVID-19 by Santos Lucio Chero Pisfil, Aimeé Yajaira Díaz Mau, José Darío Gutiérrez Vicuña

“…<strong>Fundamento:</strong> el mundo aún vive un gran problema de salud pública, el Sars-Cov-2 causa la enfermedad COVID-19, que produce principalmente infecciones respiratorias, con disnea, tos, fiebre e intolerancia al ejercicio; deja una gama de deficiencias con secuelas físicas a corto y largo plazo, que afectan la condición física y la fuerza de agarre de mano.…”
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Characterising COVID-19 school and childcare outbreaks in Canada in 2021: a surveillance study by Kaitlin Patterson, Erin McGill, Demy Dam, Anna Bellos, Cameron Mark Coulby, Rachel McCormick

“…Children remain a population of interest for SARS-CoV-2; however, severity in paediatric populations remained low throughout 2021 and the risk of transmission in Canadian schools was low.…”
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Clinical Characteristics of COVID-19 Patients with and without Diabetes in Wuhan Red Cross Hospital by Guozhen Li, Qin Deng, Jiali Feng, Fang Li, Nian Xiong, Qiong He

“…Since the end of December 2019, novel coronavirus- (SARS-CoV-2-) infected pneumonia (COVID-19) has spread rapidly in China. …”
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Design and assembly of plant-based COVID-19 candidate vaccines: reсent development and future prospects by E. A. Uvarova, P. A. Belavin, E. V. Deineko

“…An outbreak of a new variant of the coronavirus infection, known as COVID-19, occurred at the end of 2019 in China, in the city of Wuhan. It was caused by the SARS-CoV-2 virus. This variant of the virus is characterized by a high degree of variability and, as the current situation with its spread across different regions of the globe shows, it can lead to a progressive spread of infection among the human population and become the cause of a pandemic. …”
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Exploration of the anti-inflammatory potential of Polygonum bistorta L.: protection against LPS-induced acute lung injury in rats via NF-ĸβ pathway inhibition by Sajida Parveen, Kashif ur Rehman Khan, Shahid Muhammad Iqbal, Hanan Y. Aati, Areej M. Al-taweel, Liaqat Hussain, Musaddique Hussain, Musaddique Hussain

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Conducting polymer-based electrochemical sensors: Progress, challenges, and future perspectives by Aashutosh Dube, Shweta J. Malode, Abdullah N. Alodhayb, Kunal Mondal, Nagaraj P. Shetti

“…Conducting polymers and their nanocomposites-based electrochemical sensors have demonstrated exceptional capabilities towards detecting various biomolecules, heavy metals, pesticides, and viruses like SARS-COV-2. Incorporation of redox mediators, use of conducting hydrogels, and molecular imprinting are promising strategies for better performance of the derived sensor. …”
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Un análisis semanal de los casos confirmados a la COVID-19 en Cuba: primeros 70 días by Mabel Anay Rodríguez Monteagudo, Raidell Avello Martínez, Alain Morejón Giraldoni, Pavel Rodríguez Monteagudo, Amanda Avello Rodríguez

“…<p><strong>Fundamento:</strong> la COVID-19, causada por el SARS-CoV2, ha evolucionado como una pandemia que contabiliza más de 1 millón de contagios y ha causado la muerte, hasta ahora, a más de 300 000 personas.…”
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Immuno-Inflammatory Characteristics in Low Severity COVID-19 Patients with Digestive Symptoms by Caihan Duan, Shengyan Zhang, Jian Wang, Wei Qian, Chaoqun Han, Xiaohua Hou

“…Patients were discharged based on negative results of rRT-PCR testing for SARS-CoV-2 from at least two sequential respiratory tract specimens collected ≥24 hours apart. …”
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Synthesis, H2S releasing properties, antiviral and antioxidant activities and acute cardiac effects of nucleoside 5′-dithioacetates by Miklós Bege, Miklós Lovas, Dániel Priksz, Brigitta Bernát, Ilona Bereczki, Rasha Ghanem Kattoub, Richárd Kajtár, Simon Eskeif, Levente Novák, Jan Hodek, Jan Weber, Pál Herczegh, István Lekli, Anikó Borbás

“…In human Calu cells, the guanosine derivative showed a moderate anti-SARS-CoV-2 effect which was also confirmed by virus yield reduction assay. …”
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CoviWall, a whole-virion-inactivated B.1.617.2 vaccine candidate, induces potent humoral and Th1 cell response in mice and protects against B.1.617.2 strain challenge in Syrian ham... by Jyotsna Dandotiya, Neeta Adhikari, Manas Ranjan Tripathy, Manas Ranjan Tripathy, Kamini Jakhar, Sudipta Sonar, Dibya Ranjan Pati, Vibhu Kanchan, Varsha S. Prasad, Jitendra Kumar, Nitesh K. Senapati, Arti Bharmoria, Neeraj Rani, Monika Lakhanpal, CS. Patil, Nishan Singh, Lovely Khan, Lavit Jambu, Naveen K. Jain, Syed Khalid Ali, Priyanka Priyadarsiny, Amulya K. Panda, Rajesh Jain, Shailendra Mani, Sweety Samal, Amit Awasthi, Amit Awasthi, Zaigham Abbas Rizvi, Zaigham Abbas Rizvi

“…Such promising results augur well for the clinical phase I trial of the CoviWall vaccine and further development against contagious SARS-CoV-2 strains in the future.…”
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Chronic lung lesions in COVID-19 survivors: predictive clinical model by Paulo A Lotufo, Juliana C Ferreira, Eloisa Bonfa, Anna S Levin, Rodrigo Caruso Chate, Marta Imamura, Esper G Kallas, Roger Chammas, Thais Mauad, Izabel Marcilio, Nelson Gouveia, Ricardo Nitrini, José Eduardo Krieger, Marcio Valente Yamada Sawamura, Michelle Louvaes Garcia, Cristiano Gomes, Guilherme Fonseca, Jorge Hallak, Luis Yu, Marcio Mancini, Maria Elizabeth Rossi, Thiago Avelino-Silva, Edivaldo M Utiyama, Aluisio C Segurado, Beatriz Perondi, Anna Miethke-Morais, Amanda C Montal, Leila Harima, Marjorie F Silva, Marcelo C Rocha, Maria Amélia de Jesus, Carolina Carmo, Clarice Tanaka, Julio F M Marchini, Thaís Guimarães, Ester Sabino, Carlos Roberto Ribeiro Carvalho, Celina Almeida Lamas, Diego Armando Cardona Cardenas, Daniel Mario Lima, Paula Gobi Scudeller, João Marcos Salge, Cesar Higa Nomura, Marco Antonio Gutierrez, Adriana L Araújo, Bruno F Guedes, Carolina S Lázari, Cassiano C Antonio, Claudia C Leite, Emmanuel A Burdmann, Euripedes C Miguel, Fabio R Pinna, Fabiane Y O Kawano, Geraldo F Busatto, Giovanni G Cerri, Heraldo P Souza, Izabel C Rios, Larissa S Oliveira, Linamara R Batisttella, Luiz Henrique M Castro, Marcello M C Magri, Maria Cassia J M Corrêa, Maria Cristina P B Francisco, Maura S Oliveira, Orestes V Forlenza, Ricardo F Bento, Rodolfo F Damiano, Rossana P Francisco, Solange R G Fusco, Tarcisio E P Barros-Filho, Wilson J Filho

“…Patients with abnormalities in at least one of these parameters underwent chest CT. mMRC scale, SpO2, FVC and CXR findings were used to build a machine learning model for lung lesion detection on CT.Setting A tertiary hospital in Sao Paulo, Brazil.Participants 749 eligible RT-PCR-confirmed SARS-CoV-2-infected patients aged ≥18 years.Primary outcome measure A predictive clinical model for lung lesion detection on chest CT.Results There were 470 patients (63%) that had at least one sign of pulmonary involvement and were eligible for CT. …”
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Genetic determinants of COVID-19 severity and mortality: ACE1 Alu 287 bp polymorphism and ACE1, ACE2, TMPRSS2 expression in hospitalized patients by João Locke Ferreira de Araújo, Átila Duque Rossi, Jessica Maciel de Almeida, Hugo José Alves, Isabela de Carvalho Leitão, Renata Eliane de Ávila, Anna Carla Pinto Castiñeiras, Jéssica da Silva Oliveira, Rafael Mello Galliez, Marlon Daniel Lima Tonini, Débora Souza Faffe, Shana Priscila Coutinho Barroso Barroso, Gustavo Gomes Resende, Cássia Cristina Alves Gonçalves, Terezinha Marta Pereira Pinto Castiñeiras, Amilcar Tanuri, Mauro Martins Teixeira, Renato Santana Aguiar, Cynthia Chester Cardoso, Renan Pedra de Souza

“…Background The angiotensin-converting enzyme 2 (ACE2) and the transmembrane serine protease 2 (TMPRSS2) are central human molecules in the SARS-CoV-2 virus-host interaction. Evidence indicates that ACE1 may influence ACE2 expression. …”
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