A Computational Study on Selected Alkaloids as SARS-CoV-2 Inhibitors: PASS Prediction, Molecular Docking, ADMET Analysis, DFT, and Molecular Dynamics Simulations by Md. Golam Mortuza, Md Abul Hasan Roni, Ajoy Kumer, Suvro Biswas, Md. Abu Saleh, Shirmin Islam, Samia Sadaf, Fahmida Akther

“…Here, our main objective is to find potential lead compounds from the retrieved alkaloids with antiviral and other biological properties that selectively target the main SARS-CoV-2 protease (Mpro), which is required for viral replication. …”
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A Truncated Multi-Thiol Aptamer-Based SARS-CoV-2 Electrochemical Biosensor: Towards Variant-Specific Point-of-Care Detection with Optimized Fabrication by Sergio Roberto Molina Ramirez, Nafiseh Samiseresht, Mateo Alejandro Martínez-Roque, Ferdinando Catania, Kevin Graef, Martin Rabe, Andreas Offenhäusser, Dirk Mayer, Gabriela Figueroa-Miranda

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Potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with SARS-CoV-2 infection and bacterial complications: Our recent experience by Gennady Meerovich, Evgeniya Kogan, Igor Romanishkin, Nikolay Zharkov, Sofiya Avraamova, Elena Shchelokova, Ekaterina Akhlyustina, Marina Strakhovskaya, Irina Meerovich, Sofya Demura, Irina Tiganova, Yulia Romanova, Zhi-Long Chen, Igor Reshetov

Subjects: “…SARS-CoV-2…”
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SARS-Cov-2 Incidence Monitoring and Statistical Estimation of the Basic and Time-Varying Reproduction Number at the Early Onset of the Pandemic in 45 Sub-Saharan African Countries. by Oduro, Michael Safo, Arhin‐Donkor, Seth, Asiedu, Louis, Kadengye, Damazo T., Iddi, Samuel

“…The world battled to defeat a novel coronavirus 2019 (SARS-CoV-2 or COVID-19), a respiratory illness that is transmitted from person to person through contact with droplets from infected persons. …”
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Exploration of slope-type geological hazard susceptibility evaluation based on dynamic correction of SBAS-InSAR technology: A case study of Kang County in Gansu Province by Rongwei Li, Pengwei Wang, Shucheng Tan, Yangbiao Zhou, Lifeng Liu, Chaodong Gou, Yalan Yu

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Advancing terrestrial snow depth monitoring with machine learning and L-band InSAR data: a case study using NASA’s SnowEx 2017 data by Ibrahim Olalekan Alabi, Ibrahim Olalekan Alabi, Hans-Peter Marshall, Jodi Mead, Ernesto Trujillo

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Critical Care Management for Novel 2019 SARS-CoV-2 and HCoV-NL63 Coinfection in a Young Immunocompromised Patient: A Chicago Experience by Alejandro Sanchez-Nadales, Miguel Treminio-Quezada, Hasan Abad, Jessica Navarro-Motta, Pamela Contreras-Chavez, Anil Kachru, Chae Chu

“…Background. SARS-CoV-2 is a newly emerged virus that has spread rapidly, exhibiting tremendous morbidity and mortality. …”
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Differences between Influenza H5N1, A/H1N1 2009, and SARS-CoV-2 in a pandemic risk scenario by Pablo I. Plaza, Sergio A. Lambertucci

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Molecular Docking, Dynamics Simulations, ADMET, and DFT Calculations: Combined In Silico Approach to Screen Natural Inhibitors of 3CL and PL Proteases of SARS-CoV-2 by Sugumar Mohanasundaram, Porkodi Karthikeyan, Venkatesan Sampath, M. Anbazhagan, Sundramurthy Venkatesa Prabhu, Jamal M. Khaled, Muthu Thiruvengadam

“…The 3D structures of the main protease and papain-like protease were used for the virtual screening to detect the potent inhibitor against SARS-CoV-2. The top-scored compounds were further analyzed for absorption, digestion, metabolism, excretion, and toxicity properties and density functional theory analysis. …”
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Holocene Bythocytheridae (Ostracoda: Podocopida) from Southwestern Atlantic deep-sea sediments off Brazil. Part 1: tribes Bythocytherini Sars, 1926 and Jonesini Schornikov, 1981 by Cristianini Trescastro Bergue, Marie-Béatrice Forel, Geise de Santana dos Anjos-Zerfass, Simone Nunes Brandão

“…ABSTRACT The Bythocytheridae Sars, 1866 is one of the oldest families of cytheroidean Ostracoda, with a fossil record dating back to the Silurian. …”
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SARS-CoV-2 infection and antibody seroprevalence in routine surveillance patients, healthcare workers and general population in Kita region, Mali: an observational study 2020–2021 by Ulla Ashorn, Per Ashorn, Nigel Klein, Samba O Sow, Camilla Ducker, Elaine Cloutman-Green, Dagmar Alber, Fadima Cheick Haidara, Juho Luoma, Laura Adubra, Henry Badji, Fatoumata Diallo, Rikhard Ihamuotila, Owen Martell, Uma U Onwuchekwa, Oumar Samaké, Awa Traore, Kevin Wilson, Yue-Mei Fan

“…Objective To estimate the degree of SARS-CoV-2 transmission among healthcare workers (HCWs) and general population in Kita region of Mali.Design Routine surveillance in 12 health facilities, HCWs serosurvey in five health facilities and community serosurvey in 16 villages in or near Kita town, Mali.Setting Kita region, western Mali; local health centres around the central (regional) referral health centre.Participants Patients in routine surveillance, HCWs in local health centres and community members of all ages in populations associated with study health centres.Main outcome measures Seropositivity of ELISA test detecting SARS-CoV-2-specific total antibodies and real-time RT-PCR confirmed SARS-CoV-2 infection.Results From 2392 routine surveillance samples, 68 (2.8%, 95% CI: 2.2% to 3.6%) tested positive for SARS-CoV-2 by RT-PCR. …”
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Anti-PL-7/PL-12 antisynthetase syndrome associated with interstitial lung disease following SARS-COV-2 infection and vaccination: A case study review by Laura García-Bravo, Ángela Villegas, Bárbara López Uceda, Anaís Mariscal, Cristina Vadillo, M Asunción Nieto Barbero, Juan Luis Rodríguez-Hermosa, Beatriz Mediero Valeros, José Carlos Plaza-Hernández, Miguel Fernández-Arquero, María Guzmán-Fulgencio, Gloria Candelas-Rodríguez, Silvia Sánchez-Ramón, Juliana Ochoa-Grullón

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Collection of SARS-CoV-2 Virus from the Air of a Clinic within a University Student Health Care Center and Analyses of the Viral Genomic Sequence by John A. Lednicky, Sripriya N. Shankar, Maha A. Elbadry, Julia C. Gibson, Md. Mahbubul Alam, Caroline J. Stephenson, Arantzazu Eiguren-Fernandez, J. Glenn Morris, Carla N. Mavian, Marco Salemi, James R. Clugston, Chang-Yu Wu

“…Abstract The progression of COVID-19 worldwide can be tracked by identifying mutations within the genomic sequence of SARS-CoV-2 that occur as a function of time. Such efforts currently rely on sequencing the genome of SARS-CoV-2 in patient specimens (direct sequencing) or of virus isolated from patient specimens in cell cultures. …”
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Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection among Kidney Transplant Recipients: A Large Single-Center Experience by Emily E. Zona, Mina L. Gibes, Asha S. Jain, Juan S. Danobeitia, Jacqueline Garonzik-Wang, Jeannina A. Smith, Didier A. Mandelbrot, Sandesh Parajuli

“…Results. Of 979 KTRs with SARS-CoV-2 infection, 381 (39%) were hospitalized. …”
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Seroconversion and dynamics of IgG anti-SARS-CoV-2 antibodies during the pandemic: A two-month observation cohort study on the population of Sleman in Indonesia by Jajah Fachiroh, Septi Kurnia Lestari, Dewi Kartikawati Paramita, Bagas Suryo Bintoro, Fatwa Sari Tetra Dewi, Lutfan Lazuardi, Cici Permata Rusadi, Erti Nur Sagenah, Eggi Arguni

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Elimination of olfactory sensory neurons by zinc sulfate inoculation prevents SARS-CoV-2 infection of the brain in K18-hACE2 transgenic mice by Ji-Hun Lee, Eun-Seon Yoo, Na-Won Kim, Won-Yong Shim, Han-Bi Jeong, Dong-Hyun Kim, Young-Jun Park, Sun-Min Seo, Jun-Won Yun, Jun Won Park, Kang-Seuk Choi, Ho-Young Lee, Jun-Young Seo, Ki Taek Nam, Je Kyung Seong, Yang-Kyu Choi

Subjects: “…SARS-CoV-2…”
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SARS-CoV-2 risk factors among symptomatic vaccinated adults attending community testing locations in the Netherlands from June 2021 till February 2022. by Claudia Laarman, Susan J Hahné, Hester E de Melker, Mirjam J Knol

“…<h4>Introduction</h4>Most studies on risk factors for a SARS-CoV-2 infection were conducted in the pre-vaccination era with many non-pharmaceutical prevention measures in place. …”
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Chemical-guided SHAPE sequencing (cgSHAPE-seq) informs the binding site of RNA-degrading chimeras targeting SARS-CoV-2 5’ untranslated region by Zhichao Tang, Shalakha Hegde, Siyuan Hao, Manikandan Selvaraju, Jianming Qiu, Jingxin Wang

“…In this report, we discovered a series of coumarin derivatives that bind to a four-way RNA helix called SL5 in the 5’ UTR of the SARS-CoV-2 RNA genome. To locate the binding site, we developed a sequencing-based method namely cgSHAPE-seq, in which an acylating probe was directed to crosslink with the 2’-OH group of ribose at the binding site to create read-through mutations during reverse transcription. cgSHAPE-seq unambiguously determined a bulged G in SL5 as the primary binding site, which was validated through mutagenesis and in vitro binding experiments. …”
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The R203M and D377Y mutations of the nucleocapsid protein promote SARS-CoV-2 infectivity by impairing RIG-I-mediated antiviral signaling. by Yongkui Li, Moran Li, Heng Xiao, Feng Liao, Miaomiao Shen, Weiwei Ge, Junxian Ou, Yuqing Liu, Lumiao Chen, Yue Zhao, Pin Wan, Jinbiao Liu, Jun Chen, Xianwu Lan, Shaorong Wu, Qiang Ding, Geng Li, Qiwei Zhang, Pan Pan

“…This study helps to understand the variability of SARS-CoV-2 in regulating host immunity.…”
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Research Progress on the Structure and Function, Immune Escape Mechanism, Antiviral Drug Development Methods, and Clinical Use of SARS-CoV-2 M^pro by Jiayi Ren, Zhengfu Zhang, Yi Xia, Daqun Zhao, Dingqin Li, Shujun Zhang

Subjects: “…SARS-CoV-2…”
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