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  15. 8395

    A case of severe Aicardi–Goutières syndrome with a homozygous RNASEH2B intronic variant by Yuri Shibata, Akimichi Shibata, Takeshi Mizuguchi, Naomichi Matsumoto, Hitoshi Osaka

    Published 2024-08-01
    “…Abstract We report a case of severe Aicardi–Goutières syndrome caused by a novel homozygous RNASEH2B intronic variant, NC_000013.10(NM_024570.4):c.65-13G > A p.Glu22Valfs*5. The patient was born with pseudo-TORCH symptoms, including intracranial calcification, cataracts, and hepatosplenomegaly. …”
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    Organic rare earth feed additive to enhance Penaeus monodon’s muscle quality: A comprehensive insights into texture, amino acid, and fatty acid composition by Jiaoping Yu, Wanqi Wang, Guowei Liao, Zhen Zhang, Yuanyuan Yao, Kaimin Cheng, Jun Hu, Yalin Yang, Zhigang Zhou, Lanfen Fan

    Published 2025-03-01
    “…Furthermore, compared to the CON group, the OREFA2 group exhibited a significantly increase in the content of umami amino acids (glycine), monounsaturated fatty acids (C18:1, C18:1(n-9), C20:1, C22:1, C24:1) and polyunsaturated fatty acids (C18:2, C18:3, C20:2, C20:4, C20:3, C20:5, C22:4, C22:6) (P < 0.05). Additionally, the relative expression levels of muscle growth-related genes PI3K (Phosphoinositide 3-kinase), TOR (target of rapamycin), AKT (Protein kinase B), S6K1 (ribosomal protein S6 kinase 1) and 4E-BP1 (4E-binding protein 1) were significantly higher in shrimp muscle compared to the CON group (P < 0.05). …”
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  18. 8398

    Assessment of toxic response of Lactuca sativa to compost extracted from agri-food waste by Diego Andr´es Zapata-Gonz´alez, Juan Manuel Trujillo-Gonz´alez, Marco Aurelio Torres-Mora, Daniel Gonz´alez-Santamaria, Raimundo Jim´enez-Ballesta

    Published 2023-10-01
    “…Results: The prepared compost showed the following parameters: pH (8.6), OM (21.4%), C/N (11.59), EC (7.24 dS/m), Total N (1.72%), P (325.6 ppm), Al (0.1 cmol.kg−1) K (41 cmol.kg−1), Ca (8.12 cmol.kg−1), Mg (5.62 cmol.kg−1), Na (0.76 cmol.kg−1). …”
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  19. 8399

    Synthesis, characterization and biological profile of some new dihydropyrimidinone derivaties by Madiha Kanwal, Humaira Nadeem, Sumra Malik, Saima Maqsood

    Published 2025-01-01
    “…All derivatives showed good binding affinities against the multiple targeted protein with. Compound 4c exhibited hightest potential with −10 kcal/mol against bacterial strains. 4b showed best antifungal potential with −10.8 kcal/mol binding affinities. …”
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