Elevated Bile Acids Induce Circadian Rhythm Sleep Disorders in Chronic Liver DiseasesSummary by Lan Zhou, Min Yan, Qin Luo, Wen Qiu, Yu-Ru Guo, Xiao-Qing Guo, Hong-Bin Yu, Jing-Ru Huo, Yan-Lin Feng, De-Ping Wang, Teng Sun, Kai-Fang Wang, Jian-Yun Shi, Xuan Shang, Mei-Na Wu, Lin Wang, Ji-Min Cao

“…Sleep-wake cycle and circadian rhythm were analyzed by electroencephalogram-electromyography and locomotor wheel-running experiments. Results: Patients with CLD showed CRSD-like phenotypes including increased night activity and early awakening, which were strongly correlated with increased BA levels (ie, cholemia). …”
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Normative Database of Spatiotemporal Gait Metrics Across Age Groups: An Observational Case–Control Study by Lianne Mobbs, Vinuja Fernando, R. Dineth Fonseka, Pragadesh Natarajan, Monish Maharaj, Ralph J. Mobbs

“…Data were collected through a Bluetooth connection to a smartphone running a custom-developed application and subsequently analysed using IMUGaitPY, a specialised version of the GaitPY Python package. …”
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Sustainability index analysis for environmentally low-input integrated farming by E. Widjaja, B.N. Utomo, A.D. Santoso, Y.P. Erlambang, . Surono, M.A. Firmansyah, S. Handoko, E. Erythrina, M.N. Rofiq, D. Iskandar, N.A. Sasongko, T. Rochmadi, N. Abbas, M. Hanif, Y.S. Garno, F.D. Arianti, N.D. Suretno, M. Askinatin, C.O.I. Hastuti, F. Fahrodji

“…Based on the findings, the factors that should be considered included 1) Efficiency in the utilization of water during egg, 2) fertilizer production and effectiveness of using fuel and electricity during the production and marketing, 3) an Industry manager level of education, 4) the ease by which raw materials can be obtained for the integration industry, 5) potential for increasing the low-input integrated agricultural farming, 6) the availability of integration industry facilities, infrastructure and level of expertise needed by managers in the people's integration sector, 7) Financial institutions' existence.CONCLUSION: Multidimensional mapping showed that the low-input integrated agricultural farming in the dry land of Pangkalan Lada District was running sustainably, with an average sustainability index of 86.10 percent. …”
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Editorial by Christian Gütl

“…Hermann Maurer, who founded the journal and successfully managed it for many years, preparing the ground for it to become one of the longest-running open content journals in computer science. …”
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Componentes y Dinámica Natural del Ambiente - Ciudad de Neuquén- by Olga Capua, Elsie Marcela Jurio

“…This is compounded by the action of running water, where runoff, predominantly concentrated, is based on two fundamental values: the intensity of rainfall, and the rate of infiltration. …”
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Effects of Physical Fatigue on Cardiopulmonary Resuscitation Quality by Lifeguards: A Systematic Review and Meta-analysis  by Filipe Maia

“…When attending to victims of cardiac arrest in the water, lifeguards must perform basic life support after intense physical exertion that may involve running, swimming, and towing. The purpose of this review is to assess the magnitude of the effects caused by physical fatigue on the quality of subsequent cardiopulmonary resuscitation, under simulated conditions. …”
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Authority and Moral Conflicts in the Films of Adébáyọ Fálétí: Àfọ̀njá, Gáà, Ṣawo Ṣẹ̀gbẹ̀rì and the Yorùbá Cosmopolis by Olayinka Agbetuyi

“…Fálétí demonstrates the mastery of dramaturgy in Àfọ̀njá and Gáà by juxtaposing the dynamics of running a state originally built on a confederation of city state structure very much like the Greek city state structure, at the latter’s comparative stage of political evolution, with a new imperial structure and the conflicts generated by the flux of the two systems; whereas in Ṣawo Ṣẹ̀gbẹ̀rì moral conflict is generated by interpersonal amatorial clashes as well as models of expertise. …”
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Architecture et réfection des aqueducs d’Orléans/Cenabum (Loiret) by Julien Courtois, Mathilde Noël, Franck Verneau

“…The second, more recent aqueduct (aqueduct C), initially runs east-west, but has been diverted to the south at the level of a masonry manhole. …”
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La flore sauvage du boulevard Dr Henri-Henrot à Reims/Durocortorum : approche carpologique de l’environnement du site et des productions de denrées végétales by Véronique Matterne, Clémence Pagnoux

“…Several species, not particularly common to the carpological assemblages, were identified, in relationship to the environments mentioned: weakly running waterways not prone to pollution, wet meadows, harvesting areas; the significant wealth of the spectrum, as well as the important number of contexts studied undoubtedly explain the presence of these rare species. …”
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HERA: a high-resolution pan-European hydrological reanalysis (1951–2020) by A. Tilloy, D. Paprotny, S. Grimaldi, G. Gomes, A. Bianchi, S. Lange, H. Beck, C. Mazzetti, L. Feyen

“…We use the new European set-up of the OS LISFLOOD model, running at 1 <span class="inline-formula">arcmin</span> (<span class="inline-formula">≈1.8</span> <span class="inline-formula">km</span>) with 6-hourly time steps. …”
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Editorial by Ann-Kristin Kölln, Antony Mason, Maria Lenk, Jörg Tremmel, Markus Rutsche

“…Nugent who contribute to this debate by arguing that lowering the eligibility age to run for office leads to better representation of the youngest and next-youngest cohorts in parliament. …”
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Decorin, an exercise-induced secretory protein, is associated with improved prognosis in breast cancer patients but does not mediate anti-tumorigenic tissue crosstalk in mice by Marit Hjorth, Casey L. Egan, Guilherme D. Telles, Martin Pal, David Gallego-Ortega, Oliver K. Fuller, Emma D. McLennan, Ryan D. Gillis, Tae Gyu Oh, George E.O. Muscat, Surafel Tegegne, Michael S.M. Mah, Joanna Skhinas, Emma Estevez, Timothy E. Adams, Matthew J. McKay, Mark Molloy, Kevin I. Watt, Hongwei Qian, Paul Gregorevic, Thomas R. Cox, Pernille Hojman, Julie Midtgaard, Jesper F. Christensen, Martin Friedrichsen, Renato V. Iozzo, Erica K. Sloan, Brian G. Drew, Jørgen F.P. Wojtaszewski, Martin Whitham, Mark A. Febbraio

“…Results: We show that voluntary wheel running slows tumor development in the mammary specific polyomavirus middle T antigen overexpression (MMTV-PyMT) mouse model of breast cancer but only when mice are not housed alone. …”
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Le sanctuaire romain du Vigneau à Pussigny (Indre-et-Loire) : un lieu de mémoire, de vie et d’accueil by Arnaud Coutelas, Sébastien Lepetz

“…A rescue archaeology excavation took place in Le Vigneau (commune of Pussigny, Indre-et-Loire, France), along the intended layout of the high-speed train line running from Tours to Bordeaux. The archaeological site developed in the upper part of the plateau overlooking the Vienne valley, along a west-facing slope.The centre of the excavation area is characterised by an ancient occupation, divided into two sectors. …”
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Designing a model to improve the behavior of Iranian handicrafts e-commerce customers by increasing customer trust by mohsen seidi, Fataneh Alizadeh Meshkani, Ahmad Sardari, Abdullah Naami

“…According to the results obtained from the research, it is suggested: 1- The development of Iranian handicrafts in the context of e-commerce should be considered as one of the important strategies to increase the market share of these industries, because unlike traditional retail, a craft e-commerce store can be up and running with just a few clicks. The e-commerce platform makes it easy and simple for craft business owners to create attractive and reliable sites with minimal effort. 2- Training and promoting the use of sales in the context of e-commerce by relevant organizations should be prioritized. …”
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Le camp légionnaire romain de Mayence/Mogontiacum (Allemagne) : nouveaux résultats sur l’enceinte et la chronologie by Daniel Burger-Völlmecke

“…On the new rear rampart, which had been moved forward, a new earth-and-timber rampart was constructed, the posts of which were also set into parallel running trenches. To date, it was only possible to locate the presence of this new rampart in the north-western section of the rear rampart. …”
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Antiviral efficacy of fluoxetine in early symptomatic COVID-19: an open-label, randomised, controlled, adaptive platform trial (PLATCOV)Research in context by Podjanee Jittamala, Simon Boyd, William H.K. Schilling, James A. Watson, Thundon Ngamprasertchai, Tanaya Siripoon, Viravarn Luvira, Elizabeth M. Batty, Phrutsamon Wongnak, Lisia M. Esper, Pedro J. Almeida, Cintia Cruz, Fernando R. Ascencao, Renato S. Aguiar, Najia K. Ghanchi, James J. Callery, Shivani Singh, Varaporn Kruabkontho, Thatsanun Ngernseng, Jaruwan Tubprasert, Wanassanan Madmanee, Kanokon Suwannasin, Amornrat Promsongsil, Borimas Hanboonkunupakarn, Kittiyod Poovorawan, Manus Potaporn, Attasit Srisubat, Bootsakorn Loharjun, Walter R.J. Taylor, Farah Qamar, Abdul Momin Kazi, M. Asim Beg, Danoy Chommanam, Sisouphanh Vidhamaly, Kesinee Chotivanich, Mallika Imwong, Sasithon Pukrittayakamee, Arjen M. Dondorp, Nicholas P.J. Day, Mauro M. Teixeira, Watcharapong Piyaphanee, Weerapong Phumratanaprapin, Nicholas J. White

“…Methods: PLATCOV is an open-label, multicentre, phase 2, randomised, controlled, adaptive pharmacometric platform trial running in Thailand, Brazil, Pakistan, and Laos. We recruited low-risk adult outpatients aged 18–50 with early symptomatic COVID-19 (symptoms <4 days) between 5 April 2022 and 8 May 2023. …”
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Application of artificial intelligence in the management of patients with renal dysfunction by Bo Zhang, Xiaocong Jiang, Jie Yang, Jiajie Huang, Chaoming Hu, Yucai Hong, Hongying Ni, Zhongheng Zhang

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An active shrinkage and antioxidative hydrogel with biomimetic mechanics functions modulates inflammation and fibrosis to promote skin regeneration by Tao Zhang, Xin-Cao Zhong, Zi-Xuan Feng, Xiao-Ying Lin, Chun-Ye Chen, Xiao-Wei Wang, Kai Guo, Yi Wang, Jun Chen, Yong-Zhong Du, Ze-Ming Zhuang, Yong Wang, Wei-Qiang Tan

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3D bioprinting lobule-like hepatorganoids with induced vascularization for orthotopic implantation by Jianing Yan, Zhichao Ye, Yiwei Lu, Yuyang Yuan, Xiaofeng Wang, Tingting Yan, Jun Yin, Yifan Wang

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Impact of leachate from boiled-water-treated plastic products on male reproductive health: Insights from transcriptomic and metabolomic profiling by Xinghua Yu, Rui Yao, Ge Meng, Lingan Zeng, Leyi Zhou, Yingkang Shen, Amali Upekshika Wijayaraja, Reshmi Hareendra Kariyapperuma, Wentao Xu, Yuxiang Mei, Xinyan Gu, Wen-Long Lei, Pengfei Zhang, Fei Sun

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