Production of β-lactoglobulin (BLG) gene knock- out blastocyst stage embryos of Indian water buffalo using CRISPR and SCNT technology by Aseem Tara, Priyanka Singh, Devika Gautam, Gaurav Tripathi, Shreya Malhotra, Sacchinandan De, Manoj K. Singh, Naresh L. Selokar

“…Keeping this in mind, we planned to utilize the CRISPR tools to disrupt the buffalo β-lactoglobulin (BLG) gene to produce hypoallergenic milk in the long run. In pursuit of our objectives, we designed three single guide RNAs (sgRNAs) targeting the BLG locus in buffalo. …”
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Direct-acting oral anticoagulant removal by intraoperative hemoadsorption in CABG and/or single valve surgery: interim analysis of the International Safe and Timely Antithrombotic... by Michael Schmoeckel, Matthias Thielmann, Keti Vitanova, Thomas Eberle, Nandor Marczin, Kambiz Hassan, Andreas Liebold, Sandra Lindstedt, Georg Mächler, Marijana Matejic-Spasic, Daniel Wendt, Efthymios N. Deliargyris, Robert F. Storey

“…Methods The hemoadsorption device was incorporated into the cardiopulmonary bypass (CPB) circuit and active for the duration of the pump run. Patients on DOACs undergoing CABG and/or single valve surgery before completing the recommended washout were included. …”
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Ukrainian Patients’ Perspectives on Advanced Pharmaceutical Services Provided by Polish Pharmacists: A Cross-Border Support Initiative by Merks P, Religioni U, Borowska M, Hechman R, Konstanty M, Kaźmierczak J, Chełstowska B, Vaillancourt R, Drab A, Wdowiak K

“…As part of the project, Ukrainian patients who had run out of medicines due to war brought their medications to pharmacy counselling points organized by Polish pharmacists, and the pharmacists helped them find equivalents ias well as help treated minor ailments in Poland.Results: Practically all respondents strongly agree with all the statements posed in the survey, the percentage of such responses was close to 95%, with the lowest percentage observed for the statement “If possible, I would like this kind of service to be offered in any Polish pharmacy”, which was 90.40%.Conclusion: Ukrainian patients highly appreciated the pharmaceutical consultation services provided by Polish pharmacists. …”
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Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics by George S. Biggs, Emma E. Cawood, Aini Vuorinen, William J. McCarthy, Harry Wilders, Ioannis G. Riziotis, Antonie J. van der Zouwen, Jonathan Pettinger, Luke Nightingale, Peiling Chen, Andrew J. Powell, David House, Simon J. Boulton, J. Mark Skehel, Katrin Rittinger, Jacob T. Bush

“…Data-independent acquisition performed on a Bruker timsTOF Pro 2 consistently identified ~23,000 cysteine sites per run, with a total of ~32,000 cysteine sites profiled in HEK293T and Jurkat lysate. …”
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The scoping, design, and plasma physics optimization of the Eos neutron source stellarator by C.P.S. Swanson, D.A. Gates, S.T.A. Kumar, M.F. Martin, T.G. Kruger, D.W. Dudt, P.J. Bonofiglo, the Thea Energy team

“…At this foundational stage of the design, analytic and approximate models are sufficient to capture the leading-order effects, and fast enough to run in the inner loop of an optimizer. Higher-fidelity analyses will follow. …”
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Simultaneous Determination of 13 Constituents of Radix Polygoni Multiflori in Rat Plasma and Its Application in a Pharmacokinetic Study by Wenhao Cheng, Yinghui Li, Wei Yang, Siyang Wu, Mengmeng Wei, Yang Gao, Chen Kang, Shuofeng Zhang, Yingfei Li

“…Chromatographic separation was performed using a waters HSS C18 column with a gradient elution using water and acetonitrile both containing 0.025% formic acid within a run time of 9 min. The constituents were detected in negative ionization mode using multiple reaction monitoring. …”
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Deep Learning and Automatic Detection of Pleomorphic Esophageal Lesions—A Necessary Step for Minimally Invasive Panendoscopy by Miguel Martins, Miguel Mascarenhas, Maria João Almeida, João Afonso, Tiago Ribeiro, Pedro Cardoso, Francisco Mendes, Joana Mota, Patrícia Andrade, Hélder Cardoso, Miguel Mascarenhas-Saraiva, João Ferreira, Guilherme Macedo

“…The data were divided into the training/validation and test groups, in a patient-split design. Three runs were conducted, each with unique patient sets. …”
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Pengembangan Sistem Manajemen Pengetahuan di Organisasi Asosiasi Alumni Program Beasiswa Amerika - Indonesia (ALPHA-I) by Muhammad Nurwegiono, Sri Nurdiati, Sony Hartono Wijaya

“…The result of black box testing from 36 case studies demonstrated that all functions in the system run according to the commands given. …”
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Effects of vitamin D supplementation in patients with rheumatoid arthritis: A systematic review and meta-analysis by Mahsa Ranjbar, Mehran Rahimlou, Maryam Fallah, Kurosh Djafarian, Hamed Mohammadi

“…Evidence shows that Vitamin D modulates immunologic function and inflammation by affecting various immunological cells. We decided to run a systematic review and meta-analysis to investigate the relationship between vitamin D supplementation and the outcomes of adult patients suffering from RA. …”
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Deciphering the Link Between Diagnosis-Related Group Weight and Nursing Care Complexity in Hospitalized Children: An Observational Study by Manuele Cesare, Fabio D’Agostino, Emanuele Sebastiani, Nursing and Public Health Group, Gianfranco Damiani, Antonello Cocchieri

“…Stepwise regression was run to identify the key determinants of medical complexity across sociodemographic, clinical, organizational, and nursing variables. …”
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Mono-allelic epigenetic regulation of polycistronic transcription initiation by RNA polymerase II in Trypanosoma brucei by Rudo Kieft, Laura Cliffe, Haidong Yan, Robert J. Schmitz, Stephen L. Hajduk, Robert Sabatini

“…RNA-seq, Pol II ChIP, and run-on analysis indicate HpHbR silencing is at the transcriptional level, where loss of Pol II binding at the promoter region specifically shuts down transcription of the HpHbR-containing gene cluster and the adjacent opposing gene cluster. …”
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Effects of biochar on the chemical properties of soils and the volume of wood in a plantation of Acacia mangium Willd in the Colombian Orinoquía (highlands) by Giovanni Reyes-Moreno, Aquiles Enrique Darghan, Carlos Rivera-Moreno

“…Volume in wood was used as the response, and the same soil variables were used to run a regression by partial least squares where the explanatory variables were characterized by relative importance. …”
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Preparing healthcare leaders of the digital age with an integrative artificial intelligence curriculum: a pilot study by Soo Hwan Park, Roshini Pinto-Powell, Thomas Thesen, Alexander Lindqwister, Joshua Levy, Rachael Chacko, Devina Gonzalez, Connor Bridges, Adam Schwendt, Travis Byrum, Justin Fong, Shahin Shahsavari, Saeed Hassanpour

“…From September 2022 to March 2023, ten self-selected first-year students enrolled in the elective curriculum run in parallel with four existing curricular blocks (Immunology, Hematology, Cardiology, and Pulmonology). …”
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Dairy Foods in a Moderate Energy Restricted Diet Do Not Enhance Central Fat, Weight, and Intra-Abdominal Adipose Tissue Losses nor Reduce Adipocyte Size or Inflammatory Markers in... by Marta D. Van Loan, Nancy L. Keim, Sean H. Adams, Elaine Souza, Leslie R. Woodhouse, Anthony Thomas, Megan Witbracht, Erik R. Gertz, Brian Piccolo, Andrew A. Bremer, Michael Spurlock

“…A 15-week controlled feeding study to determine if dairy foods enhance central fat and weight loss when incorporated in a modest energy restricted diet of overweight and obese adults. Design. A 3-week run-in to establish energy needs; a 12-week 500 kcal/d energy reduction with 71 low-dairy-consuming overweight and obese adults randomly assigned to diets: ≤1 serving dairy/d (low dairy, LD) or ≤4 servings dairy/d (adequate dairy, AD). …”
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Exercise-based cardiac rehabilitation for patients with atrial fibrillation receiving catheter ablation: protocol for a feasibility randomised controlled trial (RCT) with embedded... by Gregory Y H Lip, Helen Jones, Mark T Mills, Dhiraj Gupta, Lawrence Foweather, Benjamin JR Buckley, Charlotte Fitzhugh

“…The intervention consists of supervised exercise sessions run by a clinical exercise physiologist and psychoeducation sessions. …”
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A Method for the Simultaneous Determination of Chlorogenic Acid and Sesquiterpene Lactone Content in Industrial Chicory Root Foodstuffs by Honorine Willeman, Philippe Hance, Anne Fertin, Najia Voedts, Nathalie Duhal, Jean-François Goossens, Jean-Louis Hilbert

“…The profiling of CGA and STL content was performed through a conventional HPLC-DAD method using a PFP core shell column in a fast single run. Good retention time and area repeatability (RDD mean % 0.46 and 5.6, resp.) and linearity (R2≥0.96) were obtained. …”
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The saprotrophic Pleurotus ostreatus species complex: late Eocene origin in East Asia, multiple dispersal, and complex speciation by Jing Li, Li-Hong Han, Xiao-Bin Liu, Zhi-Wei Zhao, Zhu L. Yang

“…Comprehensive sampling from Asia, Europe, North and South America and Africa was used to run phylogenetic analyses of the P. ostreatus species complex based on 40 nuclear single-copy orthologous genes using maximum likelihood and Bayesian inference analyses. …”
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Teknologi Realitas Virtual pada Perangkat Bergerak untuk Media Pengenalan Lingkungan Haji by Usaid Syawahidul Chaq, Febriliyan Samopa

“…This must be prepared seriously so that the implementation of the Hajj pilgrimage can run smoothly according to the rules and not become a wasted Hajj. …”
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Prevalence, aetiology, and service mapping of dementia in rural Uganda. Part of DEPEND Uganda (Dementia Epidemiology, unmet Need and co-Developing Solutions in Uganda). [version 2;... by Joseph Mugisha, Nicholas J Ashton, Claire J Steves, Racheal Alinaitwe, Josephine Prynn, Tunde Peto, Beatrice Kimono, Martin Prince

“…Methods The study is nested within the General Population Cohort run by the Medical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine Research Unit. …”
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OPTIMIZATION PROBLEM FOR NUMBER OF LOGIC GATES NEEDED TO IMPLEMENT MULTIPLE BOOLEAN FUNCTIONS USING DECODER by M. Onai, H. Skopyk

“…It is estimated that the implementations proposed by the program require on average 0.75 of the initial number of LEs. The average running time is estimated at 2 milliseconds. In contrast, brute-force search for the same problem is theorized to run for years. …”
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