Efficacy of Single-Pill Combination of Telmisartan 80 mg and Hydrochlorothiazide 25 mg in Patients with Cardiovascular Disease Risk Factors: A Prospective Subgroup Analysis of a Ra... by Harold Bays, Pingjin Gao, Birgit Völker, Michaela Mattheus, Luis M. Ruilope, Dingliang Zhu

“…Hypertensive patients were randomized (2 : 1) to receive T80/H25 or T80 for 6 weeks, following a 1-week, low-dose, and run-in period. Systolic blood pressure (SBP) and diastolic BP reductions and BP goal achievement were evaluated in patients with CVD risk factors: presence of diabetes mellitus (DM), renal impairment, increased body mass index (BMI), and 10-year estimated risk for coronary heart disease (CHD). …”
Get full text

Sensor Placement Strategies for the Seismic Monitoring of Complex Vaulted Structures of the Modern Architectural Heritage by Erica Lenticchia, Rosario Ceravolo, Paola Antonaci

“…As a general requirement, permanent systems must include a sensing network able to run a continuous surveillance and provide reliable analyses based on different information sources. …”
Get full text

HPLC method with monolithic column for simultaneous determination of irbesartan and hydrochlorothiazide in tablets by Alanazi Amer M., Abdelhameed Ali S., Khalil Nasr Y., Khan Azmat A., Darwish Ibrahim A.

“…The proposed method had high throughput as the analysis involved a simple procedure and a very short run- -time of < 3 min. The results demonstrated that the method is applicable in the quality control of combined pharmaceutical tablets containing IRB and HCT…”
Get full text

Design of Archimedes Screw Turbine by Multi-step Selections on Parameter Pitch Distance, Blade Number, and Blade Angle by Sarjito, Agus Dwi Anggono, Wijianto, Fauzan Anas Wirawan, Sidik Kurniawan, Bagus Dwi Nugroho

“…One of the water turbines called an Archimedes screw turbine (ASTs) is appropriate to run in a low head of just less than 5 m and works at a wide range of discharge operations. …”
Get full text

Economic feasibility study of Litopenaeus vannamei shrimp farming: nanobubble investment in increasing harvest productivity by Syifa Mauladani, Asri Ifani Rahmawati, Muhammad Fahrurrozi Absirin, Rizki Nugraha Saputra, Aprian Fajar Pratama, Arief Hidayatullah, Agus Dwiarto, Ahmad Syarif, Hardi Junaedi, Dedi Cahyadi, Henry Kasman Hadi Saputra, Wendy Tri Prabowo, Ujang Komarudin Asdani Kartamiharja, Alfian Noviyanto, Nurul Taufiqu Rochman

“…The total investment required to run this farming practice is IDR 182,887,700. Total revenue per cycle is estimated at IDR 157,850,000 with the selling price of IDR 70,000/kg of shrimp. …”
Get full text

Patients Walking Faster After Anterior Cruciate Ligament Reconstruction Have More Gait Asymmetry by Rachel J. Knobel, Naoaki Ito, Elanna K. Arhos, Jacob J. Capin, Thomas S. Buchanan, Lynn Snyder-Mackler

“…Univariate correlations were run for walking speed and each variable in the ACLR knee, contralateral knee, and interlimb difference (ILD)…”
Get full text

Utilization of a Lightweight 3D U-Net Model for Reducing Execution Time of Numerical Weather Prediction Models by Hyesung Park, Sungwook Chung

“…Despite its ability to run on less powerful servers, Low GloSea6 still requires significant computational resources like those of high-performance computing (HPC) clusters. …”
Get full text

OCCUPATIONAL HEALTH AND SAFETY PRACTICES IN THE WORKPLACE DURING THE COVID-19 PANDEMIC: A LITERATURE REVIEW by Ana Islamiyah Syamila, Reny Indrayani, Ragil Ismi Hartanti, Anita Dewi Prahastuti Sujoso

“…Result: Various innovations have been made by companies so that the implementation of Occupational Health and Safety (OHS) management, especially health protocols in dealing with COVID-19, can run optimally. Among them is an increasing number of training sessions for workers on health protocols and awareness, redesigning workplaces according to standards, using smart technology to detect social distancing violations, and improving dialogic communication. …”
Get full text

Gd3+-Doped Magnetic Nanoparticles for Biomedical Applications by A. P. Budnyk, T. A. Lastovina, A. L. Bugaev, V. A. Polyakov, K. S. Vetlitsyna-Novikova, M. A. Sirota, K. G. Abdulvakhidov, A. G. Fedorenko, E. O. Podlesnaya, A. V. Soldatov

“…The magnetic hyperthermia test was performed on 1 and 2 mg/ml aqueous colloidal solutions of MNPs and demonstrated their ability to rise the temperature by 3°C during a 20–30 min run. Therefore, the obtained Gd3+ MNPs are the promising material for biomedicine.…”
Get full text

A Special, Strict, Fat-Reduced, and Carbohydrate-Modified Diet Leads to Marked Weight Reduction even in Overweight Adolescents with Prader-Willi Syndrome (PWS) by Walter Bonfig, Kathi Dokoupil, Heinrich Schmidt

“…Previously, we reported that our special diet for PWS patients is effective in the long run, if started early at about 2 years of age. Our objective in this study was to investigate if our special diet is also effective in PWS adolescents who are already overweight. …”
Get full text

Connexin 43 Communication Channels in Follicular Dendritic Cell Development and in Follicular Lymphomas by Hajnalka Rajnai, Ivett Teleki, Gergo Kiszner, Nora Meggyesházi, Peter Balla, Tamas Vancsik, Gyorgyi Muzes, Judit Csomor, Andras Matolcsy, Tibor Krenacs

“…In tissues, Cx43 protein levels run parallel with the density of FDC both in reactive germinal centers and in malformed follicles of follicular lymphomas and showed strong upregulation in newly generated and/or degrading bi-/multinuclear FDC of rudimentary processes. …”
Get full text

Folliculin Interacting Protein 1 (FNIP-1) expression and capillary density in gastrocnemius muscle tissue of mice after biological maturation period by Sinta Ayu Choiriyah, Bambang Purwanto, Viskasari Pintoko Kalanjati, Raden Argarini, Anisah Rosydiyah

“…Conclusion: This study concludes maturation was characterized by a low distribution of FNIP-1 expression in the gastrocnemius muscle and a longer duration ability to run on the treadmill. Unfortunately the capillary density was not a specific mark to determine maturation in mice. …”
Get full text

GATA4 binding to the Sox9 enhancer mXYSRa/Enh13 is critical for testis differentiation in mouse by Yuya Ogawa, Iku Tsuchiya, Shogo Yanai, Takashi Baba, Ken-Ichirou Morohashi, Takehiko Sasaki, Junko Sasaki, Miho Terao, Atsumi Tsuji-Hosokawa, Shuji Takada

“…In vivo binding assay by CUT&RUN revealed that GATA4 binds to the sequence. In vitro luciferase assay showed that GATA4 promotes the enhancer activity and the substitution of the sequence reduces the effect. …”
Get full text

Hybrid metaheuristic artificial neural networks for stock price prediction considering efficient market hypothesis by Milad Shahvaroughi Farahani, Hamed Farrokhi-Asl, Saeed Rahimian

“…The experimental results clearly indicate that a hybrid ANN-HS algorithm outperforms other algorithms regarding stock price prediction accuracy. Finally, we conduct run tests, a non-parametric test, to evaluate the Efficient Market Hypothesis (EMH) in its weak form.…”
Get full text

Rationale and Design of a Randomized, Open‐Label, Parallel‐Group Study of Esaxerenone Versus Angiotensin Receptor Blockers in Older Patients With Uncontrolled Hypertension on Calci... by Kazuomi Kario, Tomohiro Katsuya, Tatsuo Shimosawa, Takashi Taguchi, Ayumi Tanabe, Mitsuru Ohishi, the ESCORT‐HT investigators

“…The ESCORT‐HT study is a multicenter, randomized, controlled, open‐label, parallel‐group study with a 4‐week run‐in period and 12‐week treatment period. This study aims to evaluate the efficacy of esaxerenone as a second‐line treatment for hypertension and to determine whether its BP‐lowering effect is noninferior to that of ARBs in older patients with uncontrolled hypertension on CCB monotherapy. …”
Get full text

Leveraging Next-Generation Sequencing Application from Identity to Purity Profiling of Nucleic Acid-Based Products by Rucha Wadapurkar, Swarda Deo, Renuka Khanzode, Ajay Singh

“…Perhaps NGS adaptation under cGMP compliance needs to be deliberated with the regulatory bodies, especially focusing on the methods qualification and validation part, starting from the sample collection, NGS library preparation, NGS run, and its data analysis pipeline.…”
Get full text

Time in Russian and Japanese Lingo-cultures by N. E. Gorelova

“…The question of their commensuration is one of the key questions for the theory and practice ofintercultural communication, considering the influence of cultural differences on the run of the communicative event, its "success" or "failure." …”
Get full text

Can a low-threshold check-up motivate older adults to schedule a dental visit? Study protocol for a randomized controlled trial by Aster De Vleeschauwer, Louise Poppe, Roos Colman, Barbara Janssens

“…Key strategies include enhancing oral health knowledge, identifying existing oral issues, and involving family physicians. The study, set to run from April 2024 to March 2025, aims to inform future evidence-based oral health promotion strategies for community-dwelling older adults. …”
Get full text

Long-term health consequences and costs of changes in alcohol consumption in England during the COVID-19 pandemic. by Joshua Card-Gowers, Sadie Boniface, Jamie Brown, Loren Kock, Alexander Martin, Lise Retat, Laura Webber

“…Disease incidence, mortality, and healthcare costs were modelled for nine alcohol-related health conditions. The model was run from 2020 to 2035 for the population of England and different occupational social grade groups.…”
Get full text

Extensive In Silico Analysis of ATL1 Gene : Discovered Five Mutations That May Cause Hereditary Spastic Paraplegia Type 3A by Mujahed I. Mustafa, Naseem S. Murshed, Abdelrahman H. Abdelmoneim, Miyssa I. Abdelmageed, Nafisa M. Elfadol, Abdelrafie M. Makhawi

“…The raw data of ATL1 gene were retrieved from dbSNP database and then run into numerous computational analysis tools. …”
Get full text