Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS) by Robert Chen, Angus G K McNair, Vafa Rahimi-Movaghar, Julio C Furlan, Benjamin M Davies, Oliver D Mowforth, Iwan Sadler, Bizhan Aarabi, Brian K Kwon, Michael G Fehlings, James S Harrop, Armin Curt, Ellen Sarewitz, Carl Moritz Zipser, Timothy F Boerger, Mark R N Kotter, James Milligan, Lindsay Tetreault, Danyal Khan, Keng Siang Lee, Alvaro Yanez Touzet, Ricardo Rodrigues-Pinto, James D Guest, Sukhvinder Kalsi-Ryan, Shirley Widdop

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Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAIN mechanism by Bartlomiej Taciak, Maciej Bialasek, Malgorzata Kubiak, Ilona Marszalek, Malgorzata Gorczak, Olha Osadchuk, Daria Kurpiel, Damian Strzemecki, Karolina Barwik, Marcin Skorzynski, Julia Nowakowska, Waldemar Lipiński, Łukasz Kiraga, Jan Brancewicz, Robert Klopfleisch, Łukasz Krzemiński, Emilia Gorka, Anna Smolarska, Irena Padzinska-Pruszynska, Małgorzata Siemińska, Jakub Guzek, Jan Kutner, Marlena Kisiala, Krzysztof Wozniak, Giacomo Parisi, Roberta Piacentini, Luca Cassetta, Lesley M. Forrester, Lubomir Bodnar, Tobias Weiss, Alberto Boffi, Paulina Kucharzewska, Tomasz P. Rygiel, Magdalena Krol

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Effects on maternal and pregnancy outcomes of first-trimester malaria infection among nulliparous women from Kenya, Zambia, and the Democratic Republic of the Congo. by Sequoia I Leuba, Daniel Westreich, Carl L Bose, Andrew F Olshan, Steve M Taylor, Antoinette Tshefu, Adrien Lokangaka, Waldemar A Carlo, Elwyn Chomba, Musaku Mwenechanya, Edward A Liechty, Sherri L Bucher, Osayame A Ekhaguere, Fabian Esamai, Paul Nyongesa, Saleem Jessani, Sarah Saleem, Robert L Goldenberg, Janet L Moore, Tracy L Nolen, Jennifer Hemingway-Foday, Elizabeth M McClure, Marion Koso-Thomas, Richard J Derman, Matthew Hoffman, Steven R Meshnick, Melissa Bauserman

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A catalogue of land-based adaptation and mitigation solutions to tackle climate change by Maria Vincenza Chiriacò, Claudia Dămătîrcă, Sara Abd Alla, Sara Barilari, Rebeca Biancardi Aleu, Tommaso Brazzini, Tiago Capela Lourenço, Carlotta Annamaria de Carolis Villars, Suzie Durand, Giulio Di Lallo, Ricardo Encarnação Coelho, Océane Espin, Noelia Ferreras-Alonso, Giulia Galluccio, Daniel Ganszky, Sofie Hellsten, Gema Hernández-Moral, Jane Ihrfors, Iphigenia Keramitsoglou, Chris T. Kiranoudis, Attila Nemethy, Robert Oakes, Jesús Ortuño Castillo, Amandine Valérie Pastor, Patricia Pérez-Ramirez, Iván Ramos-Diez, Panagiotis Sismanidis, Chiara Trozzo, Chiara De Notaris

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Genome sequences of four Ixodes species expands understanding of tick evolution by Alexandra Cerqueira de Araujo, Benjamin Noel, Anthony Bretaudeau, Karine Labadie, Matéo Boudet, Nachida Tadrent, Benjamin Istace, Salima Kritli, Corinne Cruaud, Robert Olaso, Jean-François Deleuze, Maarten J. Voordouw, Caroline Hervet, Olivier Plantard, Aya Zamoto-Niikura, Thomas Chertemps, Martine Maïbèche, Frédérique Hilliou, Gaëlle Le Goff, Jindřich Chmelař, Vilém Mazák, Mohamed Amine Jmel, Michalis Kotsyfakis, José María Medina, Michael Hackenberg, Ladislav Šimo, Fotini A. Koutroumpa, Patrick Wincker, Petr Kopáček, Jan Perner, Jean-Marc Aury, Claude Rispe

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Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorecta... by Romy Walker, Jihoon E. Joo, Khalid Mahmood, Mark Clendenning, Julia Como, Susan G. Preston, Sharelle Joseland, Bernard J. Pope, Ana B.D. Medeiros, Brenely V. Murillo, Nicholas Pachter, Kevin Sweet, Allan D. Spigelman, Alexandra Groves, Margaret Gleeson, Krzysztof Bernatowicz, Nicola Poplawski, Lesley Andrews, Emma Healey, Steven Gallinger, Robert C. Grant, Aung K. Win, John L. Hopper, Mark A. Jenkins, Giovana T. Torrezan, Christophe Rosty, Finlay A. Macrae, Ingrid M. Winship, Daniel D. Buchanan, Peter Georgeson

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Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome by Hugh D. Goold, Heinrich Kroukamp, Paige E. Erpf, Yu Zhao, Philip Kelso, Julie Calame, John J. B. Timmins, Elizabeth L. I. Wightman, Kai Peng, Alexander C. Carpenter, Briardo Llorente, Carmen Hawthorne, Samuel Clay, Niël van Wyk, Elizabeth L. Daniel, Fergus Harrison, Felix Meier, Robert D. Willows, Yizhi Cai, Roy S. K. Walker, Xin Xu, Monica I. Espinosa, Giovanni Stracquadanio, Joel S. Bader, Leslie A. Mitchell, Jef D. Boeke, Thomas C. Williams, Ian T. Paulsen, Isak S. Pretorius

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BenthicNet: A global compilation of seafloor images for deep learning applications by Scott C. Lowe, Benjamin Misiuk, Isaac Xu, Shakhboz Abdulazizov, Amit R. Baroi, Alex C. Bastos, Merlin Best, Vicki Ferrini, Ariell Friedman, Deborah Hart, Ove Hoegh-Guldberg, Daniel Ierodiaconou, Julia Mackin-McLaughlin, Kathryn Markey, Pedro S. Menandro, Jacquomo Monk, Shreya Nemani, John O’Brien, Elizabeth Oh, Luba Y. Reshitnyk, Katleen Robert, Chris M. Roelfsema, Jessica A. Sameoto, Alexandre C. G. Schimel, Jordan A. Thomson, Brittany R. Wilson, Melisa C. Wong, Craig J. Brown, Thomas Trappenberg

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Growth, physical, and cognitive function in children who are born HIV-free: School-age follow-up of a cluster-randomised trial in rural Zimbabwe. by Joe D Piper, Clever Mazhanga, Marian Mwapaura, Gloria Mapako, Idah Mapurisa, Tsitsi Mashedze, Eunice Munyama, Maria Kuona, Thombizodwa Mashiri, Kundai Sibanda, Dzidzai Matemavi, Monica Tichagwa, Soneni Nyoni, Asinje Saidi, Manasa Mangwende, Dzivaidzo Chidhanguro, Eddington Mpofu, Joice Tome, Gabriel Mbewe, Batsirai Mutasa, Bernard Chasekwa, Handrea Njovo, Chandiwana Nyachowe, Mary Muchekeza, Kuda Mutasa, Virginia Sauramba, Ceri Evans, Melissa J Gladstone, Jonathan C Wells, Elizabeth Allen, Melanie Smuk, Jean H Humphrey, Lisa F Langhaug, Naume V Tavengwa, Robert Ntozini, Andrew J Prendergast

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True Mass and Atmospheric Composition of the Nontransiting Hot Jupiter HD 143105 b by Luke Finnerty, Yinzi Xin, Jerry W. Xuan, Julie Inglis, Michael P. Fitzgerald, Shubh Agrawal, Ashley Baker, Randall Bartos, Geoffrey A. Blake, Benjamin Calvin, Sylvain Cetre, Jacques-Robert Delorme, Greg Doppmann, Daniel Echeverri, Katelyn Horstman, Chih-Chun Hsu, Nemanja Jovanovic, Joshua Liberman, Ronald A. López, Emily C. Martin, Dimitri Mawet, Evan Morris, Jacklyn Pezzato-Rovner, Jean-Baptiste Ruffio, Ben Sappey, Tobias Schofield, Andrew Skemer, Taylor Venenciano, J. Kent Wallace, Nicole L. Wallack, Jason J. Wang, Ji Wang

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An oligodendrocyte silencer element underlies the pathogenic impact of lamin B1 structural variants by Bruce Nmezi, Guillermo Rodriguez Bey, Talia DeFrancesco Oranburg, Kseniia Dudnyk, Santana M. Lardo, Nathan Herdman, Anastasia Jacko, Sandy Rubio, Emanuel Loeza-Alcocer, Julia Kofler, Dongkyeong Kim, Julia Rankin, Emma Kivuva, Nicholas Gutowski, Katherine Schon, Jelle van den Ameele, Patrick F. Chinnery, Sérgio B. Sousa, Filipe Palavra, Camilo Toro, Filippo Pinto e Vairo, Jonas Saute, Lisa Pan, Murad Alturkustani, Robert Hammond, Francois Gros-Louis, Michael S. Gold, Yungki Park, Geneviève Bernard, Raili Raininko, Jian Zhou, Sarah J. Hainer, Quasar S. Padiath

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Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation. by Alexandra Schuetz, Claire Deleage, Irini Sereti, Rungsun Rerknimitr, Nittaya Phanuphak, Yuwadee Phuang-Ngern, Jacob D Estes, Netanya G Sandler, Suchada Sukhumvittaya, Mary Marovich, Surat Jongrakthaitae, Siriwat Akapirat, James L K Fletscher, Eugene Kroon, Robin Dewar, Rapee Trichavaroj, Nitiya Chomchey, Daniel C Douek, Robert J O Connell, Viseth Ngauy, Merlin L Robb, Praphan Phanuphak, Nelson L Michael, Jean-Louis Excler, Jerome H Kim, Mark S de Souza, Jintanat Ananworanich, RV254/SEARCH 010 and RV304/SEARCH 013 Study Groups

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Phase I study of intratumoral administration of CV8102 in patients with advanced melanoma, squamous cell carcinoma of the skin, squamous cell carcinoma of the head and neck, or ade... by Lucie Heinzerling, Michael Fluck, Caroline Robert, Celeste Lebbe, Erika Richtig, Sven D Koch, Ulrike Gnad-Vogt, Tobias Seibel, Thomas Eigentler, Juan Martin-Liberal, Sebastian Ochsenreither, Peter Mohr, Patrick Terheyden, Carsten Weishaupt, Michael Erdmann, Lukas Koch, Ainara Soria, Igor Samoylenko, Jürgen Krauß, Peter Brossart, Franz Georg Bauernfeind, Marina Gonzalez, Peter Wengenmayer, Ioannis Thomas, Artem Poltoratskiy, Marina Sekacheva, Beate Schmitt-Bormann, Gianluca Quintini, Martin Falk, Paula Codó, Arjun Oberoi, Jana Hess, Yulia Semiletova, Casilda Llacer Perez, Oliver Schönborn-Kellenberger

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NEUROlogical Prognosis After Cardiac Arrest in Kids (NEUROPACK) study: protocol for a prospective multicentre clinical prediction model derivation and validation study in children... by Elizabeth S Draper, John Pappachan, Kent Thorburn, David Inwald, Richard Feltbower, Buvana Dwarakanathan, Patrick Davies, Kate Penny-Thomas, James Martin, Rum Thomas, Kevin P Morris, Roger Parslow, Timothy Thiruchelvam, Sophie Skellett, Hari Krishnan Kanthimathinathan, Victoria Hiley, Peter Barry, Sian Cooper, Rohit Saxena, Cormac Breatnach, Barnaby Robert Scholefield, Sarah Evans, Mirjam Kool, Alice J Sitch, Fang Smith, Yamuna Thiru, Richard Levin, Rachel Agbecko, James Weitz, Akash Deep, Sandra Gala-Peralta, Milly Lo, Rachael Barber, Stewart Reid, Siva Oruganti, Kalai Sadasivam, Mark Bebbington

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Comparison of Diffusion Tensor Imaging Metrics in Normal-Appearing White Matter to Cerebrovascular Lesions and Correlation with Cerebrovascular Disease Risk Factors and Severity by Seyyed M. H. Haddad, Christopher J. M. Scott, Miracle Ozzoude, Courtney Berezuk, Melissa Holmes, Sabrina Adamo, Joel Ramirez, Stephen R. Arnott, Nuwan D. Nanayakkara, Malcolm Binns, Derek Beaton, Wendy Lou, Kelly Sunderland, Sujeevini Sujanthan, Jane Lawrence, Donna Kwan, Brian Tan, Leanne Casaubon, Jennifer Mandzia, Demetrios Sahlas, Gustavo Saposnik, Ayman Hassan, Brian Levine, Paula McLaughlin, J. B. Orange, Angela Roberts, Angela Troyer, Sandra E. Black, Dar Dowlatshahi, Stephen C. Strother, Richard H. Swartz, Sean Symons, Manuel Montero-Odasso, null ONDRI Investigators, Robert Bartha

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Increased glenoid baseplate retroversion improves internal rotation following reverse shoulder arthroplasty by Lisa A. Galasso, MD, Bryce N. Clinger, MD, Brian C. Werner, MD, Patrick J. Denard, MD, Albert Lin, Anthony Romeo, Anup Shah, Asheesh Bedi, Benjamin W. Sears, Bradford Parsons, Brandon Erickson, Bruce Miller, Christopher O. Grady, Daniel Davis, David Lutton, Dirk Petre, Evan Lederman, Justin Griffin, John Tokish, Jorn Steinbeck, Julia Lee, Kevin Farmer, Mathew Provencher, Michael Bercik, Michael Kissenberth, Patric Raiss, Peter Habermeyer, Philipp Moroder, Robert Creighton, G. Russell Huffman, Samuel Harmsen, Sven Lichtenberg, Tim Lenters, Matthew Tyrrell Burrus, Tyler Brolin

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A Binational Sample-Initiated Retrospective Outbreak Investigation of Listeria monocytogenes Infections in the United States and Canada Linked to Enoki Mushrooms Imported from Chin... by Margaret Kirchner, Alexandra Palacios, Natalie Cataldo, Kate L. Allen, Allison Wellman, Asma Madad, Temesgen Jemaneh, Timothy Jackson, David T. Ingram, Victoria Wagoner, Robert Hatch, Joseph Baugher, Laurel Burall, Kenneth Nieves, Mabel Low, Grace Pederson, Lauren DiPrete, Victoria Sepcic, Deepam Thomas, Kristen Lozinak, Sinisa Urban, Kyle Shannon, Erin Kafka, Ainsley Lackey, Lauren Edwards, Hilary E. Rosen, Christian Bond, Michael Needham, Annie Locas, Austin Markell, Kelvin Chau, Adrienne Kong, Meghan Hamel, Ashley Kearney, Monique Salter, Laura Gieraltowski, Michael C. Bazaco, Stelios Viazis, Amanda Conrad

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Nomenclatural issues concerning cultured yeasts and other fungi: why it is important to avoid unneeded name changes by Andrey Yurkov, Artur Alves, Feng-Yan Bai, Kyria Boundy-Mills, Pietro Buzzini, Neža Čadež, Gianluigi Cardinali, Serge Casaregola, Vishnu Chaturvedi, Valérie Collin, Jack W. Fell, Victoria Girard, Marizeth Groenewald, Ferry Hagen, Chris Todd Hittinger, Aleksey V. Kachalkin, Markus Kostrzewa, Vassili Kouvelis, Diego Libkind, Xinzhan Liu, Thomas Maier, Wieland Meyer, Gábor Péter, Marcin Piątek, Vincent Robert, Carlos A. Rosa, Jose Paulo Sampaio, Matthias Sipiczki, Marc Stadler, Takashi Sugita, Junta Sugiyama, Hiroshi Takagi, Masako Takashima, Benedetta Turchetti, Qi-Ming Wang, Teun Boekhout

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SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocolsResearch in context by Moreno Ursino, Guillermo Villacampa, Jan Rekowski, Munyaradzi Dimairo, Olga Solovyeva, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Thomas R. Jeffry Evans, Elizabeth Garrett-Mayer, Robert M. Golub, Christina Guo, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Adrian Mander, Lynley V. Marshall, James Matcham, Dhrusti Patel, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Mahtab Rouhifard, Lesley Seymour, Yoshiya Tanaka, Christopher J. Weir, Johann de Bono, Christina Yap

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CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context by Jan Rekowski, Christina Guo, Olga Solovyeva, Munyaradzi Dimairo, Mahtab Rouhifard, Dhrusti Patel, Emily Alger, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Johann de Bono, Thomas R. Jeffry Evans, Elizabeth Garrett–Mayer, Robert M. Golub, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Israel Maia, Adrian Mander, Lynley V. Marshall, James Matcham, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Lesley Seymour, Yoshiya Tanaka, Moreno Ursino, Christopher J. Weir, Christina Yap

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