Application of continuous improvement process in reducing the return-cleaning rate of lumen surgical instruments (质量持续改进活动在降低手术管腔器械清洗返洗率中的应用)... by JIANG Linghua (蒋玲华), LI Shaoping (李绍平), YAO Shixiu (姚仕秀), YANG Weizao (杨伟造)

“…The current situation of lumen surgical instruments cleaning was investigated, and existing problems and potential risk factors were analyzed. Targeted strategies were carried out by a PDCA circle and implementation effect was evaluated. …”
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Association of the Monocyte to High-Density Lipoprotein Cholesterol Ratio and Neutrophil to High-Density Lipoprotein Cholesterol Ratio With the Severity of New-Onset Coronary Arter... by Shu H, Han S, Qiu W, Li J, Zhang X, Su H, Wu H, Zhao G, Li Q

“…The relationship between MHR and NHR with CAD was validated through logistic regression analysis, adjusting for traditional cardiovascular risk factors and medication therapy. The nonlinear relationship between MHR and NHR with CAD and GS was assessed by using restricted cubic spline (RCS) models. …”
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Correlation Between Dynamic Contrast-Enhanced CT Imaging Signs and Differentiation Grade and Microvascular Invasion of Hepatocellular Carcinoma by Liu Y, Zhou Y, Liao C, Li H, Zhang X, Gong H, Pu H

“…Multivariate Logistic regression analysis identified ALBI score, PT level, CT value in PVP, and tumor capsule as independent risk factors for MVI occurrence (AUC: 0.71, 0.58, 0.66, and 0.60). …”
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Estimating Trends in Cardiovascular Disease Risk for the EXPOSE (Explaining Population Trends in Cardiovascular Risk: A Comparative Analysis of Health Transitions in South Africa a... by Shaun Scholes, Jennifer S Mindell, Mari Toomse-Smith, Annibale Cois, Kafui Adjaye-Gbewonyo

“…Demographic, behavioral, socioeconomic, health care, and psychosocial variables considered risk factors for CVD are routinely measured in population health surveys, providing opportunities to examine health transitions. …”
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Genetic Polymorphisms in RNF138, ABCA1 and ESRRG-GPATCH2 Genes and their Role in Insulin Resistance Risk among Normal BMI Individuals in Indian Population: A Case-control Study by Sabitha Thummala, Sarah Fathima, Nithya Kruthi, Junaid Ahmed Khan Ghori, Katherine Saikia, Vivek Belde, Balamurali Andiyakkal Rajendran, Rahul Ranganathan

“…Conclusion: This study underscores the importance of genetic factors in the risk of developing IR among Indians with a normal BMI, suggesting a complex interplay of genetics beyond traditional risk factors. These findings necessitate further research into the functional significance of these associations and their potential implications for targeted interventions and preventive strategies in high-risk populations.…”
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Faktor-Faktor Yang Mempengaruhi Kejadian Insomnia di Poliklinik Saraf RS DR. M. Djamil Padang by Lydia Susanti

“…<br />Kata Kunci: insomnia, tidur, insomnia severity index, beck depression inventory scale<br /><br />Abstract <br />A number of risk factors such as advanced age, female gender, co-morbidities (such as depression and other diseases), low socioeconomic status causes insomnia. …”
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Predictors of late complications after coronary artery bypass grafting in patients with stable coronary heart disease by O.J. Zharinov, К.O. Mikhaliev, O.A. Yepanchintseva, B.M. Todurov

“…Groups of patients with and without complications were compared according to demographic parameters, risk factors, concomitant diseases, laboratory parameters, features of the CABG operation and postoperative therapy. …”
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Relationship between BMI, indicators of lipid metabolism and diabetic neuropathy: a Mendelian randomization study by Yuanyuan Jia, Guanying Liu, Xuesong Li, Lijun Duan, Lifeng Zhao

“…Results IVW analysis showed that BMI (P = 0.033, OR = 2.53, 95% CI 1.08–5.96) and triglycerides level (P = 0.593, OR = 1.11, 95% CI 0.77–1.60) were positively associated with the initiation of DN, indicating that the values of BMI and triglycerides are potentially the risk factors in DN development. Additionally, TC was negatively associated with the DN (P = 0.069, OR = 0.72, 95% CI = 0.50–1.03).The forest plot of advanced analysis between BMI and DN relationship indicated a positive correlation between increasing BMI and the risk of DN. …”
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Clinical features of early multiple sclerosis by I. Čelpačenko, R. Stankevičiūtė, M. Malciūtė, R. Balnytė

“…The data was obtained from medical records and included sex, age, neurological signs and symptoms, risk factors associated with MS, and final diagnosis. …”
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Lifestyle risk behaviours among adolescents: a two-year longitudinal study of the impact of the COVID-19 pandemic by Nicola Clare Newton, Maree Teesson, Jennifer Debenham, Cath Chapman, Bridie Osman, Lauren Anne Gardner, Fiona Elizabeth Wylie, Katrina Elizabeth Champion

“…Objective To examine changes in the prevalence of six key chronic disease risk factors (the “Big 6”), from before (2019) to during (2021) the COVID-19 pandemic, among a large and geographically diverse sample of adolescents, and whether differences over time are associated with lockdown status and gender.Design Prospective cohort study.Setting Three Australian states (New South Wales, Queensland and Western Australia) spanning over 3000 km.Participants 983 adolescents (baseline Mage=12.6, SD=0.5, 54.8% girl) drawn from the control group of the Health4Life Study.Primary outcomes The prevalence of physical inactivity, poor diet (insufficient fruit and vegetable intake, high sugar-sweetened beverage intake, high discretionary food intake), poor sleep, excessive recreational screen time, alcohol use and tobacco use.Results The prevalence of excessive recreational screen time (prevalence ratios (PR)=1.06, 95% CI=1.03 to 1.11), insufficient fruit intake (PR=1.50, 95% CI=1.26 to 1.79), and alcohol (PR=4.34, 95% CI=2.82 to 6.67) and tobacco use (PR=4.05 95% CI=1.86 to 8.84) increased over the 2-year period, with alcohol use increasing more among girls (PR=2.34, 95% CI=1.19 to 4.62). …”
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Genetic-epigenetic aspects of infertility in women with long-COVID-19 by O.G. Boichuk, I.S. Golovchak, T.V. Kolomiichenko

“…The aim of the study is to determine the genetic and epigenetic features of infertile patients with long-term COVID-19 in order to clarify the risk factors for the failure of assisted reproductive technologies (ART) use. …”
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Prioritizing breast cancer surgeries: insights from the KRONOS SCORE by Lucía Navarro, Lucía Navarro, Lucía Navarro, Luis Perez-Bartivas, Luis Perez-Bartivas, Luis Perez-Bartivas, David Ponferrada, David Ponferrada, David Ponferrada, Javier Cejas, Javier Cejas, Javier Cejas, Juan Adrián Camús, Juan Adrián Camús, Juan Adrián Camús, Natalia Rangel, Natalia Rangel, Natalia Rangel, Maria Porras, Cristina Morales Estevez, Cristina Morales Estevez, Cristina Morales Estevez, Amalia Palacios Eito, Amalia Palacios Eito, Amalia Palacios Eito, Pilar Rioja, Pilar Rioja, Pilar Rioja, Marina Alvarez, Marina Alvarez, Marina Alvarez, Enrique Aranda, Enrique Aranda, Enrique Aranda, Juan De La Haba-Rodríguez, Juan De La Haba-Rodríguez, Juan De La Haba-Rodríguez

“…The KRONOS SCORE offers a tool for prioritizing surgical patients based on risk factors. However, further multicenter and prospective studies are needed to validate these findings and the KRONOS SCORE model’s effectiveness in different clinical settings.…”
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Duration of Disease and Long‐Term Outcomes in Patients With Difficult‐To‐Treat Recurrent Pericarditis: A Chronic Condition Treated With Nonsteroidal Anti‐Inflammatory Drugs, Colchi... by Elisa Ceriani, Francesco Agozzino, Silvia Berra, Antonio Gidaro, Paolo Bindi, Alberto Pavarani, Silvia Macchi, Letizia Vena, Francesco Moda, Ludovico Luca Sicignano, Celeste Ambra Murace, Laura Gerardino, Elena Verrecchia, Caterina Chiara De Carlini, Silvia Maestroni, Gabriella Marinaro, Emanuele Bizzi, Antonio Brucato, Massimo Imazio

“…Objective We aimed to investigate the remission rate and disease duration in idiopathic or post–cardiac injury pericarditis and risk factors for disease duration and anti–interleukin‐1 (IL‐1) agent discontinuation. …”
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Prediction model and scoring system for in-hospital mortality risk in infants with heart failure aged 1–36 months: A retrospective case-control study by Meng Wei, Shuai Shang, Huasheng Lv, Xiaoyan Liang, Yanmei Lu, Baopeng Tang

“…Multivariate Logistic regression results show that TP < 65 g/L (OR = 2.34), pH < 7.35 (OR = 2.79), and Respiratory rate (1–12 months: <30times/min and 13–36 months: <25times/min, OR = 2.34) are independent risk factors. The model evaluation results for the train and test sets of infant and toddler heart failure patients are as follows: C-index values for discrimination in the train and test sets are 0.721 and 0.728, respectively. …”
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Impact of Preoperative and Intraoperative Factors on Postoperative Outcomes in Patients with Colorectal Cancer: A 10-Year Retrospective Study by Lucian Flavius Herlo, Ioana Golu, Alexandra Herlo, Claudia Raluca Balasa Virzob, Ionescu Alin, Stela Iurciuc, Ionut Eduard Iordache, Luana Alexandrescu, Doina Ecaterina Tofolean, Raluca Dumache

“…Recognizing these risk factors allows for better preoperative optimization and surgical planning, potentially reducing postoperative morbidity and mortality.…”
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A practical distribution pattern of α-SMA-positive carcinoma associated fibroblasts indicates poor prognosis of patients with pancreatic ductal adenocarcinoma by Bo Li, Meilong Shi, Yang Wang, Penghao Li, Xiaoyi Yin, Guoxiao Zhang, Xiaochao Kang, Huan Wang, Suizhi Gao, Kailian Zheng, Xiaohan Shi, Xiongfei Xu, Yukun Zhou, Hui Jiang, Wei Jing, Shiwei Guo, Gang Jin

“…Multivariable Cox proportional hazards regression was used to assess risk factors associated with patient outcomes. RNA sequencing data were obtained from bulk tumor samples and isolated CAFs from patients to reveal the distinct pattern and elucidated their fundamental characteristics.Results The α-SMA spatial intensity was the most suitable variable for representative of CAFs spatial characteristics. …”
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Prominent efficacy and good safety of sequential CD19 and CD22 CAR-T therapy in relapsed/refractory adult B-cell acute lymphoblastic leukemia by Tingting Yang, Yetian Dong, Mingming Zhang, Jingjing Feng, Shan Fu, Pingnan Xiao, Ruimin Hong, Huijun Xu, Jiazhen Cui, Simao Huang, Guoqing Wei, Delin Kong, Jia Geng, Alex H. Chang, He Huang, Yongxian Hu

“…Higher baseline leukemia burden (≥ 64% bone marrow blasts) and the presence of EMD were significant risk factors for inferior OS and LFS, respectively. Conclusions Sequential CAR-T cell therapy demonstrated durable efficacy and a manageable safety profile in R/R B-ALL, providing a viable option to address antigen-loss relapse and improve long-term outcomes in high-risk adult patients.…”
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Prevalence and determinants of nasal carriage of penicillin non-susceptible Streptococcus pneumoniae: a cross-sectional household survey in northern VietnamResearch in context by Costanza Tacoli, Hien Anh Thi Nguyen, Tu Cam Thi Nguyen, Bich Ngoc Thi Vu, Max van Wijk, Quynh Dieu Pham, Huong Kieu Thi Tran, Thuong Hong Thi Nguyen, Trang Thu Nguyen, Tung Son Trinh, Dung Tien Viet Vu, Hoang Huy Tran, Thai Duy Pham, Duc Anh Dang, Tien Dac Tran, Duong Thanh Nguyen, H. Rogier van Doorn, Thomas Kesteman, Sonia Lewycka

“…Logistic regression models were used to explore risk factors for PNSP carriage compared to susceptible strains. …”
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Development and Validation of a Nomogram for Predicting Long-Term Net Adverse Clinical Events in High Bleeding Risk Patients Undergoing Percutaneous Coronary Intervention by Junyan Zhang, Zhongxiu Chen, Ran Liu, Yuxiao Li, Hongsen Zhao, Yanning Li, Minggang Zhou, Hua Wang, Chen Li, Li Rao, Yong He

“…Results: This study included 1512 patients with PCI-HBR, including 1058 in the derivation cohort and 454 in the validation cohort. We revealed five risk factors after LASSO regression, Cox regression, and clinical significance screening. …”
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Ten-year outcomes of repeat keratoplasty for optical indications by Victoria Grace Dimacali, Hon Shing Ong, Hon Shing Ong, Hon Shing Ong, Hon Shing Ong, Stephanie Shuang Lang, Hla Myint Htoon, Hla Myint Htoon, Howard Cajucom-Uy, Hui Chen Charmaine Chai, Hui Chen Charmaine Chai, Marcus Ang, Marcus Ang, Anshu Arundhati, Anshu Arundhati, Anshu Arundhati, Jodhbir S. Mehta, Jodhbir S. Mehta, Jodhbir S. Mehta

“…Cox multiple regression analysis showed male gender (p = 0.023), PK regraft (p = 0.003), regraft rejection (p = 0.003), and initial graft indications of pseudophakic bullous keratopathy (p = 0.005) and aphakic bullous keratopathy (p = 0.004) to be risk factors for regraft failure, while longer time to regraft was associated with decreased risk of failure (p = 0.013).ConclusionPerforming EK for failed optical PK or EK significantly improved regraft survival compared to repeat PK. …”
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