Considerations of HLA, Renal Failure, Valproic Acid Use, and Current Treatment Guidelines in Clozapine-Induced Agranulocytosis by Melissa Sussman, Michael Epifania, Derrick Eng, Yun Jae Cho, Richard Steward

“…Retrospective considerations of this case and management highlight risk factors such as HLA status, renal failure, and concurrent valproic acid use which presently do not have official screening, guidelines, or restrictions in place when prescribing clozapine. …”
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Primary Spontaneous Pneumothorax Admitted in Emergency Unit: Does First Episode Differ from Recurrence? A Cross-Sectional Study by S. Kepka, J. C. Dalphin, A. L. Parmentier, J. B. Pretalli, M. Gantelet, N. Bernard, F. Mauny, T. Desmettre

“…Management of primary spontaneous pneumothorax (PSP) consists of immediate resolution of pleural air, or observation, and prevention of recurrence. The risk factors for recurrence remain debated. Objectives. …”
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Effects of early maternal care on anxiety and threat learning in adolescent nonhuman primates by Elyse L. Morin, Erin R. Siebert, Brittany R. Howell, Melinda Higgins, Tanja Jovanovic, Andrew M. Kazama, Mar M. Sanchez

“…Early life adverse experiences, including childhood maltreatment, are major risk factors for psychopathology, including anxiety disorders with dysregulated fear responses. …”
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RELATIONSHIP BETWEEN EMOTIONAL INSTABILITY AND RISK OF ALCOHOL ABUSE AMONG ADOLESCENTS: THE MODERATING ROLE OF PREDISPOSITION TO ENGAGE IN RISKY BEHAVIORS by IONAȘCU Grigore, GLĂVAN Aurelia, ROBU Viorel

“…Understanding the risk factors associated with adolescent alcohol misuse is crucial for the development of prevention programs. …”
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Factor associated with and risk of cardiovascular disease in people with uncontrolled hypertension by Sara Ringwald-de Meyer, Roxane de La Harpe, Peter Vollenweider, Pedro Marques-Vidal, Julien Vaucher

“…We investigated the association between hypertension status (uncontrolled, defined as systolic blood pressure [SBP] ≥ 140 mm Hg and/or diastolic blood pressure [DBP] ≥ 90 mm Hg, versus controlled hypertension [SBP/DBP < 140/90 mm Hg]) and potential risk factors. Additionally, the prospective association of uncontrolled hypertension with cardiovascular disease and all-cause mortality was evaluated. 1040 participants recruited between 2003 and 2006 with a mean follow-up of 12.3 years (SD ± 3.4) were included in the analyses. …”
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A Narrative Review of Diabetes Intervention Studies to Explore Diabetes Care Opportunities for Pharmacists by Shamala Ayadurai, H. Laetitia Hattingh, Lisa B. G. Tee, Siti Norlina Md Said

“…Diabetes management includes multifactorial intervention which includes seven factors as outlined in diabetes guidelines, namely, glycaemic, cholesterol and blood pressure control, medication, lifestyle, education, and cardiovascular risk factors. Most studies do not provide evidence that the intervention methods used included all seven factors with exception of three RCT which indicated HbA1c (glycated hemoglobin) reduction range of 0.5% to 1.8%. …”
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Classical swine fever: a retrospective analysis of the epizootic situation in the Russian Federation (2007–2021) and forecast for 2022 by A. S. Oganesyan, A. A. Shevtsov, A. V. Shcherbakov, F. I. Korennoy, A. K. Karaulov

“…The introduction and spread of CSF in the Russian Federation are, most likely, associated with the internal risk factors (i.e. quality of anti-epizootic measures, mainly vaccination) and with the territories, where the virus circulates in wild boars. …”
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Retinal Displacement: Providing New Insights for Retinal Detachment Surgery by Olivier Houle, Eunice You, Mélanie Hébert, Shicheng Jin, Susan Ruyu Qi, Ali Dirani

“…To review the current literature on retinal displacement and provide a discussion of potential risk factors, postoperative outcomes, and future directions. …”
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FROM ONCOLOGIST TO SURGEON - GENETICS IN COLORECTAL METASTASIS FOR SURGEONS by Marília Polo Mingueti e SILVA, Jorge SABBAGA, Henry Luiz NAJMAN, Carlos David Carvalho NASCIMENTO, Ricardo Lemos COTTA-PEREIRA, João Eduardo Leal NICOLUZZI, Maria Ignez BRAGHIROLI

“…ABSTRACT Colorectal cancer (CRC) is a common disease, with incidence in Brazil of 45,630 new cases per 100,000 inhabitants between 2023-2025. Risk factors for CRC can be evaluated between environmental and hereditary and their mode of presentation are classified as sporadic, inherited and familial. …”
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Ischemic colitis presenting as a colonic mass: a case report and diagnostic challenges by Lin Xu, Yuqi Wu, Yuqi Wu, Shangjin Li, Shangjin Li, Xinbo Chen, Dong Zhang, Boqian Chen, Shaoju Guo

“…Ischemic colitis (IC) is a multifaceted condition that often manifests with nonspecific symptoms such as abdominal pain and bloody diarrhea, particularly in older adults with vascular risk factors. Diagnosis is supported by elevated levels of white blood cells, lactate, and C-reactive protein (CRP). …”
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The Lipodystrophy Syndrome in HIV-Infected Children under Antiretroviral Therapy: A First Report from the Central Africa by Honoré Kalombayi Tshamala, Loukia Aketi, Pierre Manianga Tshibassu, Mathilde Bothale Ekila, Eric Musalu Mafuta, Patrick Kalambayi Kayembe, Michel Ntetani Aloni, Joseph Diayisu Shiku

“…The aim of this study was to assess the prevalence and to identify the risk factors of metabolic disorders related to ARV therapy in this population. …”
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Toxic Epidermal Necrolysis (TEN)/Stevens-Johnson Syndrome (SJS) Epidemiology and Mortality Rate at King Fahad Specialist Hospital (KFSH) in Qassim Region of Saudi Arabia: A Retrosp... by Abdullah Alajaji, Jagannath Chandra Shekaran, Omar Mohammed Aldhabbah, Hajar Abdullah Alhindi, Nouf Salem Almazyad, Ziyad Abdulrahman Aljutayli, Saleh Abaalkhail, Saleh Alfouzan

“…There are multiple causative drugs and different risk factors associated with SJS/TEN. Objectives. To study the epidemiology of SJS/TEN and associated mortality rate in Qassim region, Saudi Arabia. …”
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Effects of air pollution on the development and progression of digestive diseases: an umbrella review of systematic reviews and meta-analyses by Haonan Zhao, Xiaojie Zheng, Guo Lin, Xiaomin Wang, Huiyuan Lu, Pengpeng Xie, Siqi Jia, Yiyang Shang, Yan Wang, Pengchu Bai, Xuan Zhang, Ning Tang, Xingshun Qi

“…Abstract Air pollution, especially particulate matter (PM), is one of the most common risk factors for global burden of disease. However, its effect on the risk of digestive diseases is unclear. …”
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Association between Obesity, Serum Lipids, and Colorectal Polyps in Old Chinese People by Wen Yang, Yan Chang, Haiyan Huang, Yuzhu Wang, Xiaohong Yu

“…In binary logistic regression analysis, there were two risk factors associated with the occurrence of colorectal polyps, which included BMI and systolic blood pressure. …”
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Clinical Characteristics in Patients with Triple Negative Breast Cancer by Janet Yeh, Jennifer Chun, Shira Schwartz, Annie Wang, Elizabeth Kern, Amber A. Guth, Deborah Axelrod, Richard Shapiro, Freya Schnabel

“…The purpose of this study was to compare and contrast the clinical characteristics of the triple negative breast cancer (TNBC) and non-TNBC patients, with a particular focus on genetic susceptibility and risk factors prior to diagnosis. Methods. Our institutional database was queried for all patients diagnosed with invasive breast cancer between January 2010 and May 2016. …”
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An Obesity Paradox of Asian Body Mass Index after Cardiac Surgery: Arterial Oxygenations in Duration of Mechanic Ventilation by Chiu-Hsia Chang, Fan-Yen Lee, Chin-Chou Wang, Ying-Ni Chen, Hsin-Chu Chen, Huei-Ling Hung, Meng-Chih Lin, Shih-Feng Liu

“…Under-normal weight patients have higher risk factors, longer DMV, and poorer outcomes; even though they have better arterial oxygenations, they seem to need better arterial oxygenations for successful weaning ventilator.…”
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Pretest Score for Predicting Microbubble Contrast Agent Use in Stress Echocardiography: A Method to Increase Efficiency in the Echo Laboratory by Mathieu Bernier, Sahar S. Abdelmoneim, Stuart Moir, Robert B. McCully, Patricia A. Pellikka, Sharon L. Mulvagh

“…Variables associated with microbubble use were age, sex, smoking, presence of multiple risk factors, bodymass index (BMI), referral for dobutamine stress echocardiography, history of coronary artery disease, and abnormal baseline electrocardiogram. …”
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Amino Acid Signatures to Evaluate the Beneficial Effects of Weight Loss by Nina Geidenstam, Martin Magnusson, Anders P. H. Danielsson, Robert E. Gerszten, Thomas J. Wang, Lovisa E. Reinius, Hindrik Mulder, Olle Melander, Martin Ridderstråle

“…Scores that were constructed based on obesity-associated amino acids and known risk factors decreased in the ≥10% weight loss group with an associated change in BMI (R2=0.16–0.22, p<0.002), whereas the scores increased in the <10% weight loss group (p<0.0004). …”
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Sleep Breathing Disorders’ Screening Among Children Approaching Orthodontic Evaluation: A Preliminary Study by Marco Storari, Francesca Stramandinoli, Maurizio Ledda, Alberto Verlato, Alessio Verdecchia, Enrico Spinas

“…Results: Among the 48 participants (31 females, 17 males) aged 5–12 years, 69% were identified as being at risk for SDB. Risk factors included oral breathing, nasal obstruction, tonsillar hypertrophy, malocclusion, high Friedman scores, narrow palates, and positive Brouillette phenotypes, all showing significant correlations (<i>p</i> < 0.05). …”
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The pathomechanism of bone marrow edema in the femoral head necrosis with pericollapse stage by Liang Mo, Zhangzheng Wang, Mengyu Jiang, Chi Zhou, Chao Ma, Yinuo Fan, Wei He, Zhenqiu Chen, Yuhao Liu

“…Targeted interventions aimed at neutralizing these risk factors show potential in slowing down the progression of the disease.…”
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