CyberUnits Bricks: An Implementation Study of a Class Library for Simulating Nonlinear Biological Feedback Loops by Johannes W. Dietrich, Nina Siegmar, Jonas R. Hojjati, Oliver Gardt, Bernhard O. Boehm

Get full text

Predictive value of myositis antibodies: role of semiquantitative classification and positivity for more than one autoantibody by Anne M Kerola, Arno Hänninen, Annukka Pietikäinen, Julia Barantseva, Annaleena Pajander

Get full text

Investigation of the effects of combined exercises and self-management education, with and without functional exercises, on pain and functional outcomes in patients with avascular... by Zohreh Gholami, Seyedeh Tahereh Faezi, Elham Madreseh, Raghad Mimar

Get full text

Hypoxia and lipid metabolism related genes drive proliferation migration and immune infiltration mechanisms in colorectal cancer subtyping by Shansong Huang, Huiying Wang, Jiaqing Cao, Qiang Pang

Get full text

Possible Implication of Local Immune Response in Darier's Disease: An Immunohistochemical Characterization of Lesional Inflammatory Infiltrate by Clelia Miracco, Francesco Pietronudo, Vasileios Mourmouras, Michele Pellegrino, Monica Onorati, Maria Grazia Mastrogiulio, Luca Cantarini, Pietro Luzi

Get full text

Coexistence of Takayasu’s Arteritis in Patients with Inflammatory Bowel Diseases by Camilla de Almeida Martins, Ana Elisa Rabe Caon, Carolina Bortolozzo Graciolli Facanali, Carlos Walter Sobrado, Sergio Carlos Nahas, Rosa Maria Rodrigues Pereira, Reuma Margalit-Yehuda, Uri Kopylov, Natalia Sousa Freitas Queiroz

Get full text

Atypical Hemolytic Uremic Syndrome after Traumatic Rectal Injury: A Case Report by Ji-Hyoun Kang, Donghyun Lee, Yunchul Park

Get full text

Exploring the macro-level, meso-level and micro-level barriers and facilitators to the provision of good quality early inflammatory arthritis (EIA) care in England and Wales by Sam Norton, Cath Taylor, James Galloway, Magdalena Zasada, Mark Yates, Nicola Ayers, Zoë Ide

“…Background Evidence from a national clinical audit of early inflammatory arthritis (EIA) shows considerable variability between hospitals in performance, unexplained by controlling for case-mix.Objective To explore the macro-level, meso-level and micro-level barriers and facilitators to the provision of good quality EIA care.Methods A qualitative study within 16 purposively sampled rheumatology units across England and Wales. Quality was assessed in relation to 11 quality indicators based on clinical opinion, evidence and variability observed in the data. …”
Get full text

Relationships of dermatologic symptoms and quality of life in patients with psoriatic arthritis: analysis of two tofacitinib phase III studies by Peter C. Taylor, Andrew G. Bushmakin, Joseph C. Cappelleri, Pamela Young, Rebecca Germino, Joseph F. Merola, Gil Yosipovitch

Get full text

Optimising early detection of degenerative cervical myelopathy: a systematic review of quantitative screening tools for primary care by Salazar Jones, Sean Inzerillo, Pemla Jagtiani

Get full text

Tocilizumab, an Exploratory Treatment for Severe COVID-19 Patients by Yong Wang, Yongfeng Chen, Xiangdong Zhou

Get full text

Traditional Chinese Medicine nursing of a patient with postoperative pain after surgery for breast cancer (1例乳腺癌患者术后疼痛的中医状态调护) by CHEN Hong (陈宏), DENG Jianhua (邓建华), LI Suqian (李苏茜), ZHOU Jie (周洁), LI Ye (李野), E Haiyan (鄂海燕), ZHENG Ping (郑萍), TANG Ling (唐玲)

Get full text

Weight gain secondary to the use of oral Janus kinase inhibitors: A systematic review and meta-analysis by Grace Xiong, BHSc, Eric Yu, Martin Heung, Jaehyeong Yang, BSc, Megan Lowe, MPH, Mohannad Abu-Hilal, MD

“…Oral Janus kinase inhibitors (JAKi) are increasingly used in dermatology, rheumatology, gastroenterology, and hematology. While effective, they can cause adverse effects such as acne, nausea, cytopenia, dyslipidemia, and Herpes zoster. …”
Get full text

The Pharmacodynamic Impact of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, on Circulating Levels of Inflammatory Biomarkers in Patients with Psoriatic Arthritis: Substudy Res... by Peter H. Schafer, Peng Chen, Lorraine Fang, Andrew Wang, Rajesh Chopra

“…Association between biomarker levels and achievement of 20% improvement from baseline in modified American College of Rheumatology (ACR20) response criteria was assessed by logistic regression. …”
Get full text

Study protocol for the international Systemic Lupus Erythematosus Prospective Observational Cohort Study (SPOCS): understanding lupus and the role of type I interferon gene signatu... by Raj Tummala, Anna Berglind, Xia Wang, Henk Nab, Barnabas Desta, Edward R Hammond, Farhat Syed

“…Patients ≥18 years old with a physician diagnosis that meets the American College of Rheumatology or Systemic Lupus International Collaborating Clinics SLE classification criteria will be included. …”
Get full text

Isotemporal substitution of sedentary time with different physical activity intensities and sleep in obesity parameters across eight latin American countries by Eduardo Rossato de Victo, Diego Sales, Diego G. D. Christofaro, Mauro Fisberg, Irina Kovalskys, Pablo del Val Martín, Gerson Ferrari

Get full text

Central Nervous System Involvement in Henoch-Schonlein Purpura in Children and Adolescents by Iliyana H. Pacheva, Ivan S. Ivanov, Krastina Stefanova, Elena Chepisheva, Lyubov Chochkova, Dafina Grozeva, Angelina Stoyanova, Stojan Milenkov, Penka Stefanova, Anna Petrova

“…Diagnosis was based on the American College of Rheumatology criteria. Out of 112 children with HSP 1 case (0.9%) had CNS involvement presenting as Posterior Reversible Encephalopathy Syndrome (PRES), which may be a result of CNS vasculitis or arterial hypertension. …”
Get full text

Varied Presentations Of Patients With Systemic Lupus Erythematosus – What Makes Pakistani Lupus Patients Different by Muhammad Shahzad Manzoor, Shamaila Mumtaz, Faran Maqbool, Darakhshaan Samar, Muhammad Hammas Adil, Javaria Malik

“…Reasons for serious manifestations at initial presentation include deficiency of healthcare professionals trained in the field of Rheumatology and lack of awareness among patients. …”
Get full text

Efficacy and safety of various regional nerve blocks for postoperative analgesia in paediatric patients undergoing developmental dysplasia of the hip surgery: a protocol for system... by Lei Yang, Yu Zhang, Chen Fu, Wang Junxia, Zhijun Qin

Get full text

Therapeutic Potential of Stem Cells in Follicle Regeneration by Agnieszka Owczarczyk-Saczonek, Magdalena Krajewska-Włodarczyk, Anna Kruszewska, Łukasz Banasiak, Waldemar Placek, Wojciech Maksymowicz, Joanna Wojtkiewicz

Get full text