Revealing protein structures: crystallization of protein‐ligand complexes – co‐crystallization and crystal soaking by Barbora Kaščáková, Anna Koutská, Michaela Burdová, Petra Havlíčková, Ivana Kutá Smatanová

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Single-cell chromatin accessibility profiling reveals regulatory mechanisms and evolution in pig brains by Yue Xiang, Saixian Zhang, Yi Huang, Zhuqing Zheng, Jiahui Sun, Qiulin Zhao, Peng Zhou, Xiaolong Qi, Jingjin Li, Fuyang Xiong, Jing Xu, Shengquan Wang, Liangliang Fu, Xinyun Li

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A case of multiple small bowel intussusceptions revealing a PEUTZ-JEGHERS syndrome by Khaoula Boumeriem, MD, Kabila Badr, MD, Moatassim Billah Nabil, PhD, Nassar Ittimade, PhD, Imrani Kaoutar, PhD

“…We present a 48-year-old male with known PJS who arrived at the emergency department with right flank abdominal pain. CT imaging revealed multiple small bowel intussusceptions—most notably in the right flank—alongside hyperdense intraluminal polyps. …”
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Feeling, emotion and the company they keep: what adjectives reveal about the substantives feeling and emotion by Stéphanie Béligon

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Vaginal metatranscriptome meta-analysis reveals functional BV subgroups and novel colonisation strategies by Scott J. Dos Santos, Clara Copeland, Jean M. Macklaim, Gregor Reid, Gregory B. Gloor

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Disrupting Amh and androgen signaling reveals their distinct roles in zebrafish gonadal differentiation and gametogenesis by Kun WU, Yiming YUE, Lingling ZHOU, Zhiwei ZHANG, Hong SHAN, Huanhuan HE, Wei GE

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Correction: Computational reassessment of RNA-seq data reveals key genes in active tuberculosis. by Rakesh Arya, Hemlata Shakya, Reetika Chaurasia, Surendra Kumar, Joseph M Vinetz, Jong Joo Kim

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“Computational analysis on verbal fluency reveals heterogeneity in subjective language interests and brain structure” by Francilia Zengaffinen, Antje Stahnke, Stephan Furger, Roland Wiest, Thomas Dierks, Werner Strik, Yosuke Morishima

“…Lastly, a voxel-based brain morphometry (VBM) was conducted to reveal associations between objective (LSA) measures and structural changes in language-related brain areas.We found a positive correlation between the LSA measure cosine similarity and the subjective interest in language. …”
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Machine learning reveals immediate disruption in mosquito flight when exposed to Olyset nets by Yasser M. Qureshi, Vitaly Voloshin, Amy Guy, Hilary Ranson, Philip J. McCall, James A. Covington, Catherine E. Towers, David P. Towers

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Metabolome and transcriptome analysis reveal the effect of methyl jasmonate on phytosterol biosynthesis in Brassica napus by Xueyan Wang, Min Liu, Ruinan Yang, Xiaobo Cui, Jie Liu, Yu Zhang, Yizhou He, Li Yu, Fei Ma, Xiong Zhang, Yuanyuan Zhang, Shengyi Liu, Peiwu Li, Liangxiao Zhang

“…Additionally, an integrative analysis of the high‐resolution metabolome and transcriptome revealed that the accumulation patterns of 997 metabolites were highly correlated with their corresponding gene expression patterns. …”
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Integrated bioinformatics and machine learning reveal key genes and immune mechanisms associated with uremia by Zhiyue Sun, Zhiqiang Ding, Xiaoyang Guo, Jiangtao Li, Daoyuan Ding, Bo Wen

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In-depth functional analysis of BRD9 in fetal hematopoiesis reveals context-dependent roles by Yifan Zhang, Masaki Nomura, Koutarou Nishimura, Weijia Zang, Yui Koike, Muran Xiao, Hiromi Ito, Miki Fukumoto, Atsushi Tanaka, Yumi Aoyama, Wataru Saika, Chihiro Hasegawa, Hiromi Yamazaki, Akifumi Takaori-Kondo, Daichi Inoue

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Frontal gamma-alpha ratio reveals neural oscillatory mechanism of attention shifting in tinnitus by Xueji Feng, Xiaoyu Bao, Haiyun Huang, Zijian Wang, Wen Hu, Chenxi Xue, Zhiqing Song, Yuexin Cai, Qiyun Huang, Yuanqing Li

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Cataract induction in an arthropod reveals how lens crystallins contribute to the formation of biological glass by Amartya T. Mitra, Shubham Rathore, Augusta Jester, Ruby Hyland-Brown, J. Hassert, Joshua B. Benoit, Annette Stowasser, Elke K. Buschbeck

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Pan-cancer analysis reveals MTTP as a prognostic and immunotherapeutic biomarker in human tumors by Wenjia Wang, Yaping Gao, Yihan Liu, Shurui Xia, Jiayao Xu, Liwei Qin, Yongxu Jia, Yanru Qin

“…Further researches have revealed that MTTP exerted its functions in a variety of tissues beyond the liver and intestine, including the heart, neural tissues and antigen-presenting cells. …”
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Boolean modeling of transcriptome data reveals novel modes of heterotrimeric G‐protein action by Sona Pandey, Rui‐Sheng Wang, Liza Wilson, Song Li, Zhixin Zhao, Timothy E Gookin, Sarah M Assmann, Réka Albert

“…Conversely, some theoretical regulatory modes of the G‐protein are not supported; (2) a new mechanism of G‐protein signaling is revealed, in which Gβ regulates gene expression identically in the presence or absence of Gα; (3) guard cells and leaves favor different G‐protein modes in transcriptome regulation, supporting system specificity of G‐protein signaling. …”
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Genotyping by sequencing reveals the genetic diversity and population structure of Peruvian highland maize races by Carlos I. Arbizu, Carlos I. Arbizu, Isamar Bazo-Soto, Joel Flores, Rodomiro Ortiz, Raul Blas, Pedro J. García-Mendoza, Ricardo Sevilla, José Crossa, Alexander Grobman

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Endogenous and fluorescent sterols reveal the molecular basis for ligand selectivity of human sterol transporters by Laura Depta, Hogan P. Bryce-Rogers, Nienke J. Dekker, Anna Wiehl Bønke, Nicolò Camporese, Mingxing Qian, Yuanjian Xu, Douglas F. Covey, Luca Laraia

“…Combining this with a thorough structural analysis revealed the molecular basis for STP-specific selectivity profiles, leading to the uncovering of several new potent and selective Aster-B inhibitors and supporting the role of this protein in steroidogenesis.…”
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Novel lichen simulation and laser scan modelling to reveal lichen-covered carvings at Stonehenge by Gavin Leong, Matthew Brolly, David J. Nash

“…Denoising and visualisation revealed that the presence of R. siliquosa did not hinder the identification of carvings. …”
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Mechanistic studies of PFKFB2 reveal a novel inhibitor of its kinase activity. by Craig Eyster, Satoshi Matsuzaki, Atul Pranay, Jennifer R Giorgione, Anna Faakye, Mostafa Ahmed, Kenneth M Humphries

“…Seahorse XFe analysis revealed B2 inhibited cellular glycolysis and glycolytic capacity. …”
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