Genomics and metabolic responses reveal the effect of Candida tropicalis ZD-3 on the degradation of Gossypol by Li Zhang, Xiaolong Yang, Rongzheng Huang, Shanshan Nan, Junli Niu, Cunxi Nie, Cheng Chen, Wenju Zhang

“…Genomic correlation results showed that gene function annotation revealed 64 protein-coding genes potentially involved in gossypol catabolism, primarily encoding aldehyde dehydrogenase, aldehyde reductase, and glutathione peroxidase. …”
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Multi-omics analysis reveals the evolution, function, and regulatory mechanisms of SPF pheromones in Anurans by Puyang Zheng, Yunyun Lv, Yuzhou Gong, Gang Wang, Bin Wang, Xiuqin Lin, Xun Liao, Jianghong Ran, JiaTang Li, Feng Xie

“…Behavioral experiments further reveal a previously unknown female-attractant role of SPF in anurans. …”
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Species-wide gene editing of a flowering regulator reveals hidden phenotypic variation. by Ulrich Lutz, Ilja Bezrukov, Rebecca Schwab, Wei Yuan, Marius Kollmar, Detlef Weigel

“…Our study provides a proof of concept on how pan-genetic analysis of hub genes can reveal the true extent of genetic networks in a species.…”
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Sentinel-2 time series reveal species-specific responses in temperate conifer dieback by Hélène Carletti, Jean-Claude Gégout, Raphael Dutrieux, Jean-Baptiste Féret, Cédric Vega, Thierry Belouard, Anne Jolly, Juliette Cansell, Christian Piedallu

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The first single-cell sequencing of Plasmodiophora brassicae reveals genetic diversity and clonal dynamics by Afsaneh Sedaghatkish, Meik Kunz, Bruce D. Gossen, Mary Ruth McDonald

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Mendelian randomization analysis reveals potential association between allergic rhinitis and nasopharyngeal carcinoma by Qingfu Bao, Jianjun Zou, Changyang Wang, Haiying Wang

“…Results The analysis revealed potential associations between NPC and both allergic rhinitis and high myopia. …”
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Targeted eDNA Metabarcoding Reveals New Populations of a Range‐Limited Stonefly by Graham A. McCulloch, Stephen R. Pohe, Shaun P. Wilkinson, Tom J. Drinan, Jonathan M. Waters

“…Subsequent manual surveys confirmed the presence of two newly discovered Z. maungatuaensis populations, with COI barcoding revealing that they together represent a previously unknown, genetically divergent subclade. …”
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Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. by Lea K Davis, Dongmei Yu, Clare L Keenan, Eric R Gamazon, Anuar I Konkashbaev, Eske M Derks, Benjamin M Neale, Jian Yang, S Hong Lee, Patrick Evans, Cathy L Barr, Laura Bellodi, Fortu Benarroch, Gabriel Bedoya Berrio, Oscar J Bienvenu, Michael H Bloch, Rianne M Blom, Ruth D Bruun, Cathy L Budman, Beatriz Camarena, Desmond Campbell, Carolina Cappi, Julio C Cardona Silgado, Danielle C Cath, Maria C Cavallini, Denise A Chavira, Sylvain Chouinard, David V Conti, Edwin H Cook, Vladimir Coric, Bernadette A Cullen, Dieter Deforce, Richard Delorme, Yves Dion, Christopher K Edlund, Karin Egberts, Peter Falkai, Thomas V Fernandez, Patience J Gallagher, Helena Garrido, Daniel Geller, Simon L Girard, Hans J Grabe, Marco A Grados, Benjamin D Greenberg, Varda Gross-Tsur, Stephen Haddad, Gary A Heiman, Sian M J Hemmings, Ana G Hounie, Cornelia Illmann, Joseph Jankovic, Michael A Jenike, James L Kennedy, Robert A King, Barbara Kremeyer, Roger Kurlan, Nuria Lanzagorta, Marion Leboyer, James F Leckman, Leonhard Lennertz, Chunyu Liu, Christine Lochner, Thomas L Lowe, Fabio Macciardi, James T McCracken, Lauren M McGrath, Sandra C Mesa Restrepo, Rainald Moessner, Jubel Morgan, Heike Muller, Dennis L Murphy, Allan L Naarden, William Cornejo Ochoa, Roel A Ophoff, Lisa Osiecki, Andrew J Pakstis, Michele T Pato, Carlos N Pato, John Piacentini, Christopher Pittenger, Yehuda Pollak, Scott L Rauch, Tobias J Renner, Victor I Reus, Margaret A Richter, Mark A Riddle, Mary M Robertson, Roxana Romero, Maria C Rosàrio, David Rosenberg, Guy A Rouleau, Stephan Ruhrmann, Andres Ruiz-Linares, Aline S Sampaio, Jack Samuels, Paul Sandor, Brooke Sheppard, Harvey S Singer, Jan H Smit, Dan J Stein, E Strengman, Jay A Tischfield, Ana V Valencia Duarte, Homero Vallada, Filip Van Nieuwerburgh, Jeremy Veenstra-Vanderweele, Susanne Walitza, Ying Wang, Jens R Wendland, Herman G M Westenberg, Yin Yao Shugart, Euripedes C Miguel, William McMahon, Michael Wagner, Humberto Nicolini, Danielle Posthuma, Gregory L Hanna, Peter Heutink, Damiaan Denys, Paul D Arnold, Ben A Oostra, Gerald Nestadt, Nelson B Freimer, David L Pauls, Naomi R Wray, S Evelyn Stewart, Carol A Mathews, James A Knowles, Nancy J Cox, Jeremiah M Scharf

“…Finally we analyzed the genetic correlation between TS and OCD, revealing a genetic correlation of 0.41 (se = 0.15, p = 0.002). …”
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Design Choices for Crowdsourcing Implicit Discourse Relations: Revealing the Biases Introduced by Task Design by Valentina Pyatkin, Frances Yung, Merel C. J. Scholman, Reut Tsarfaty, Ido Dagan, Vera Demberg

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Proteome profiling of early gestational plasma reveals novel biomarkers of congenital heart disease by Ya‐Nan Yin, Li Cao, Jie Wang, Yu‐Ling Chen, Hai‐Ou Yang, Su‐Bei Tan, Ke Cai, Zhe‐Qi Chen, Jie Xiang, Yuan‐Xin Yang, Hao‐Ran Geng, Ze‐Yu Zhou, An‐Na Shen, Xiang‐Yu Zhou, Yan Shi, Rui Zhao, Kun Sun, Chen Ding, Jian‐Yuan Zhao

“…Principal component analysis revealed considerable differences between the controls and the CHDs. …”
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The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension by Sasha L. Evans, Iryna Peretiazhko, Sahil Y. Karnani, Lindsey S. Marmont, James H. R. Wheeler, Boo Shan Tseng, William M. Durham, John C. Whitney, Julien R. C. Bergeron

“…Here, we investigate the role of the Tad pilus protein RcpC from Pseudomonas aeruginosa. Our analyses reveal that RcpC forms a dodecameric periplasmic complex, anchored to the inner membrane by a transmembrane helix, and interacting with the outer membrane secretin RcpA. …”
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Transcriptomic analysis reveals the mechanism underlying salinity-induced morphological changes in Skeletonema subsalsum by Jingwen Hu, Ya Zheng, Shuang Yang, Lin Yang, Lin Yang, Qingmin You, Quanxi Wang

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Revealing the potential of biochar for heavy metal polluted seagrass remediation from microbial perspective by Jian Zhang, Cong Liu, Juan Ling, Weiguo Zhou, Youshao Wang, Hao Cheng, Xiaofang Huang, Qingsong Yang, Wenqian Zhang, Tongyin Liang, Ying Zhang, Junde Dong

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Revealing the Influence of Semantic Similarity on Survey Responses: A Synthetic Data Generation Approach by Esko Lehtonen, Tommi Buder-Grondahl, Sina Nordhoff

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Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves. by Rachel Queen, Moira Crosier, Lorraine Eley, Janet Kerwin, Jasmin E Turner, Jianshi Yu, Ahlam Alqahtani, Tamilvendhan Dhanaseelan, Lynne Overman, Hannah Soetjoadi, Richard Baldock, Jonathan Coxhead, Veronika Boczonadi, Alex Laude, Simon J Cockell, Maureen A Kane, Steven Lisgo, Deborah J Henderson

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Examination of public perceptions of microbes and microbiomes in the United States reveals insights for science communication. by Katherine Kokkinias, Katherine Pruneski, Kelly Wrighton, Nicole Kelp

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An immunoinformatic investigation on Rift Valley fever virus protein reveals possible epitopes for vaccines by Tanjir Hosen, Saaimatul Huq, Mohammad Abdullah-Al-Shoeb, Shahidul Islam, Muhammad Abul Kalam Azad

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CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer by Chunge Zhong, Wen-Jie Jiang, Yingjia Yao, Zexu Li, You Li, Shengnan Wang, Xiaofeng Wang, Wenjuan Zhu, Siqi Wu, Jing Wang, Shuangshuang Fan, Shixin Ma, Yeshu Liu, Han Zhang, Wenchang Zhao, Lu Zhao, Yi Feng, Zihan Li, Ruifang Guo, Li Yu, Fengyun Pei, Jun Hu, Xingzhi Feng, Zihuan Yang, Zhengjia Yang, Xueying Yang, Yue Hou, Danni Zhang, Dake Xu, Ren Sheng, Yihao Li, Lijun Liu, Hua-Jun Wu, Jun Huang, Teng Fei

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Bioinformatics analysis of COMMD family in pan-cancer reveals potential biomarkers and therapeutic targets by Sihan Wang, Jinglei Cheng, Zhiya Hu, Hongjun Zhao, Lifen Ye, Jingyong Li, Youyuan Deng, Ye He

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Revealing the Micro-scale Signature of Endemic Zoonotic Disease Transmission in an African Urban Setting. by Hervé Bourhy, Emmanuel Nakouné, Matthew Hall, Pierre Nouvellet, Anthony Lepelletier, Chiraz Talbi, Laurence Watier, Edward C Holmes, Simon Cauchemez, Philippe Lemey, Christl A Donnelly, Andrew Rambaut

“…The development of novel approaches that combine epidemiological and genomic data provides new opportunities to reveal the spatiotemporal dynamics of infectious diseases and determine the processes responsible for their spread and maintenance. …”
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