Single‐Cell Transcriptomics Reveals a Pivotal Role of DOCK2 in Sjögren Disease by Yiran Shen, Alexandria Voigt, Indraneel Bhattacharyya, Cuong Q. Nguyen

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Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers by I‐Ming Wang, Bin Zhang, Xia Yang, Jun Zhu, Serguei Stepaniants, Chunsheng Zhang, Qingying Meng, Mette Peters, Yudong He, Chester Ni, Deborah Slipetz, Michael A Crackower, Hani Houshyar, Christopher M Tan, Ernest Asante‐Appiah, Gary O'Neill, Mingjuan Jane Luo, Rolf Thieringer, Jeffrey Yuan, Chi‐Sung Chiu, Pek Yee Lum, John Lamb, Yves Boie, Hilary A Wilkinson, Eric E Schadt, Hongyue Dai, Christopher Roberts

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Phylogenetic evidence reveal a close relationship between Amphichorda and Ovicillium in Bionectriaceae (Hypocreales) by Yao Wang, De-Xiang Tang, Hui Chen, Qi-Rui Li, Chanhom Loinheuang, Xiang-Chun Shen

“…Phylogenetic analyses revealed a close genetic connection between Amphichorda and related genera, yet they formed distinct clades within the Bionectriaceae and were clearly differentiated. …”
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Metatranscriptomic Analysis Reveals Actively Expressed Antimicrobial-Resistant Genes and Their Hosts in Hospital Wastewater by Yusuke Ota, Fei Chen, Isaac Prah, Samiratu Mahazu, Kimiyo Watanabe, Teruaki Kinoshita, Yoshiaki Gu, Yoko Nukui, Ryoichi Saito

“…Liquid chromatography–tandem mass spectrometry analysis revealed the presence of ampicillin, sulbactam, levofloxacin, sulfamethoxazole, and trimethoprim in the sample, which could apply selective pressure on antimicrobial resistance gene expression. …”
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Snapshots of Pseudomonas aeruginosa SOS response reveal structural requisites for LexA autoproteolysis by Filippo Vascon, Sofia De Felice, Matteo Gasparotto, Stefan T. Huber, Claudio Catalano, Monica Chinellato, Riccardo Mezzetti, Alessandro Grinzato, Francesco Filippini, Lorenzo Maso, Arjen J. Jakobi, Laura Cendron

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Fisheries shocks provide an opportunity to reveal multiple recruitment sources of sardine in the Sea of Japan by Tatsuya Sakamoto, Motomitsu Takahashi, Kotaro Shirai, Tomoya Aono, Toyoho Ishimura

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Library-based analysis reveals segment and length dependent characteristics of defective influenza genomes. by Marisa Mendes, Alistair B Russell

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Trapping light, revealing properties: Laser trapping as a powerful tool for photoluminescence spectroscopy by Dr. Md. Jahidul Islam, Nashin Sayara, Tasnia Talukder, Mohammad Harun-Ur-Rashid

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Dichotomous intronic polyadenylation profiles reveal multifaceted gene functions in the pan-cancer transcriptome by Jiao Sun, Jin-Young Kim, Semo Jun, Meeyeon Park, Ebbing de Jong, Jae-Woong Chang, Sze Cheng, Deliang Fan, Yue Chen, Timothy J. Griffin, Jung-Hee Lee, Ho Jin You, Wei Zhang, Jeongsik Yong

“…Notably, our analyses of protein length changes resulting from intronic APA events revealed two distinct phenomena in proteome programming: a loss of functional domains due to significant changes in protein length or minimal alterations in C-terminal protein sequences within unstructured regions. …”
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Meta-analysis of pollen limitation reveals the relevance of pollination generalization in the Atlantic forest of Brazil. by Marina Wolowski, Tia-Lynn Ashman, Leandro Freitas

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Integrating multi-omics data to reveal the host-microbiota interactome in inflammatory bowel disease by Fengyuan Su, Meng Su, Wenting Wei, Jiayun Wu, Leyan Chen, Xiqiao Sun, Moyan Liu, Shiqiang Sun, Ren Mao, Arno R. Bourgonje, Shixian Hu

“…Finally, we discuss the challenges pertaining to the integration of multi-omics data in order to reveal host-microbiota cross-talk and offer insights into relevant future research directions.…”
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Functional analysis of Rossmann-like domains reveals convergent evolution of topology and reaction pathways. by Kirill E Medvedev, Lisa N Kinch, R Dustin Schaeffer, Nick V Grishin

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Comparative Transcriptome Analysis Reveals the Effects of a High-Protein Diet on Silkworm Midgut by Xinyi Chen, Jiahao Li, Yuxi Shan, Qiaoling Wang, Pingzhen Xu, Heying Qian, Yangchun Wu

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Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. by Kun Qu, Qiuluan Chen, Katarzyna A Ciazynska, Banghui Liu, Xixi Zhang, Jingjing Wang, Yujie He, Jiali Guan, Jun He, Tian Liu, Xiaofei Zhang, Andrew P Carter, Xiaoli Xiong, John A G Briggs

“…Using this construct we determined high-resolution structures confirming that the x3 disulfide bond has the ability to stabilize the otherwise transient locked conformations. Structural analyses reveal that wild-type SARS-CoV-2 spike can adopt two distinct locked-1 and locked-2 conformations. …”
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Mapping previously undetected trees reveals overlooked changes in pan-tropical tree cover by Shidong Liu, Jie Zhang, Li Wang, Philippe Ciais, Jianjun Zhang, Josep Penuelas, Biswajit Nath, Iskid Jacquet, Xia Wu, Shengping Ding, Wang Li, Ni Huang, Wanjuan Song, WenJian Ni, Zheng Niu

“…Here we develop an automatic detection algorithm using high-resolution satellite data (<5 m) to map pan-tropical tree cover (2015–2022), enabling identification and change analysis for previously undetected tree cover (PUTC). Our findings reveal that neglecting PUTC represents 17.31 ± 1.78% of the total pan-tropical tree cover. …”
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Integrated metabolomics and transcriptomics reveal the potential of hydroxy-alpha-sanshool in alleviating insulin resistance by Yuping Zhu, Pan Yang, Tingyuan Ren, Zhuqi Chen, Huanhuan Tian, Mingfen Wang, Chunlin Zhang

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Revealing spatio-temporal variations of soil CO2 flux at Mt. Etna volcano by Salvatore Scudero, Marco Liuzzo, Antonino D’Alessandro, Giovanni Giuffrida, Sergio Gurrieri

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DNA metabarcoding reveals diet diversity and niche partitioning by two sympatric herbivores in summer by Ruofei Li, Dandan Wang, Zhiming Cao, Yuqin Liu, Wenguo Wu, Wuhua Liu, Jianwen Zhan, Yongtao Xu

“…Linear discriminant effect size analysis revealed significant differences in forage plants between the two herbivores. …”
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Identification of Arabidopsis meiotic cyclins reveals functional diversification among plant cyclin genes. by Petra Bulankova, Svetlana Akimcheva, Nicole Fellner, Karel Riha

“…We found six A-type cyclins and a single B-type cyclin (CYCB3;1) to be expressed in male meiosis. Mutant analysis revealed that these cyclins contribute to distinct meiosis-related processes. …”
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Microplastic hotspots mapped across the Southern Ocean reveal areas of potential ecological impact by Aidan Hunter, Sally E. Thorpe, Arlie H. McCarthy, Clara Manno

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