MOLVIB vs VEDA. Revealing the best program to generate safe and reliable vibrational analysis by Silvia Antonia Brandán

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A transdisciplinary, comparative analysis reveals key risks from Arctic permafrost thaw by Susanna Gartler, Johanna Scheer, Alexandra Meyer, Khaled Abass, Annett Bartsch, Natalia Doloisio, Jade Falardeau, Gustaf Hugelius, Anna Irrgang, Jón Haukur Ingimundarson, Leneisja Jungsberg, Hugues Lantuit, Joan Nymand Larsen, Rachele Lodi, Victoria Sophie Martin, Louise Mercer, David Nielsen, Paul Overduin, Olga Povoroznyuk, Arja Rautio, Peter Schweitzer, Niek Jesse Speetjens, Soňa Tomaškovičová, Ulla Timlin, Jean-Paul Vanderlinden, Jorien Vonk, Levi Westerveld, Thomas Ingeman-Nielsen

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Transcriptome reveals the landscape of alveolar macrophages exposed to combined hypoxia with cigarette smoke extract by Qing Liu, Yushi Zhang, Ruirui Duan, Wanheng Li, Xuan Hou, Yiling Chen, Baicun Li, Ting Yang

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A minimal deterministic model reveals integration of spindle assembly and position checkpoints in mitosis by Bashar Ibrahim

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CryoEM structure of the SLFN14 endoribonuclease reveals insight into RNA binding and cleavage by Justin Van Riper, Arleth O. Martinez-Claros, Lie Wang, Hannah E. Schneiderman, Sweta Maheshwari, Monica C. Pillon

“…Here, we reconstitute active full-length human SLFN14 and report a high-resolution cryoEM reconstruction of the SLFN14•RNA complex. The structure reveals a medallion-like architecture that shares structural homology with other SLFN family members. …”
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Translatome analysis reveals cellular network in DLK-dependent hippocampal glutamatergic neuron degeneration by Erin M Ritchie, Dilan Acar, Siming Zhong, Qianyi Pu, Yunbo Li, Binhai Zheng, Yishi Jin

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Transcriptomic profiling of burn patients reveals key lactylation-related genes and their molecular mechanisms by Yang Li, Jizhong Ma, Yeping Wang, Weibin Zhan, Qian Wang

“…Immune microenvironment analysis revealed correlations with immune cell infiltration. …”
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High-throughput investigation of cyclin docking interactions reveals the complexity of motif binding determinants by Mihkel Örd, Matthew J. Winters, Mythili S. Subbanna, Natàlia de Martín Garrido, Victoria I. Cushing, Johanna Kliche, Caroline Benz, Ylva Ivarsson, Basil J. Greber, Peter M. Pryciak, Norman E. Davey

“…Cryo-electron microscopy and saturation mutagenesis studies reveal distinct binding modes and sequence features governing motif recognition, binding strength, and cyclin preference. …”
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Panoramic spatial enhanced resolution proteomics (PSERP) reveals tumor architecture and heterogeneity in gliomas by Ziyan Xu, Yunzhi Wang, Tao Xie, Rongkui Luo, Heng-Li Ni, Hang Xiang, Shaoshuai Tang, Subei Tan, Rundong Fang, Peng Ran, Qiao Zhang, Xiaomeng Xu, Sha Tian, Fuchu He, Wenjun Yang, Chen Ding

“…Our spatial proteomic data revealed distinctive proteomic features of malignant and non-malignant tumor regions and depicted the distribution of proteins from tumor centers to tumor borders and non-malignant tumor regions. …”
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Drought-induced transposon expression reveals complex drought response mechanisms in Brassica napus by Manyi Chen, Dan Luo, Hanzhao Kong, Yan Lv, Chunsheng Li, Yongguo Zhao, Qian Huang, Guangyuan Lu, Guangyuan Lu

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Coupling traction force patterns and actomyosin wave dynamics reveals mechanics of cell motion by Elisabeth Ghabache, Yuansheng Cao, Yuchuan Miao, Alex Groisman, Peter N Devreotes, Wouter‐Jan Rappel

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The Steiner tree Prosecutor: Revealing and disrupting criminal networks through a single suspect. by Fredy Troncoso, Richard Weber

“…A suspect is used as the root node, and the resulting tree reveals a probable configuration of the criminal organization to which the suspect may belong. …”
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GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome by Matthew D Sekedat, David Fenyö, Richard S Rogers, Alan J Tackett, John D Aitchison, Brian T Chait

“…In particular, a parsimonious model allowed us to accurately simulate fork movement throughout the genome and also revealed a subtle phenomenon, which we interpret as arising from low‐frequency fork arrest.…”
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A functional approach reveals cross-system bottom-up control on coral reefs by Sterling B. Tebbett, Scott D. Ling

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A comparative genomic analysis at the chromosomal-level reveals evolutionary patterns of aphid chromosomes by Chen Huang, Bingru Ji, Zhaohui Shi, Jiangyue Wang, Jiaqing Yuan, Peng Yang, Xiao Xu, Haohao Jing, Lulu Xu, Jing Fu, Le Zhao, Yandong Ren, Kun Guo, Gang Li

“…Additionally, our analysis revealed that the mutation and expansion of detoxification gene families in S. heraclei may be a key factor in adapting to host plant chemical defenses. …”
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A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation by Alex Y. Ge, Abolfazl Arab, Raymond Dai, Albertas Navickas, Lisa Fish, Kristle Garcia, Hosseinali Asgharian, Jackson Goudreau, Sean Lee, Kathryn Keenan, Melissa B. Pappalardi, Michael T. McCabe, Laralynne Przybyla, Hani Goodarzi, Luke A. Gilbert

“…Our integrated multiomics approach reveals RNA dynamics are key regulators of DNA hypomethylation induced cell death. …”
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EEG oscillations reveal neuroplastic changes in pain processing associated with long-term meditation by Juliana Yordanova, Valentina Nicolardi, Peter Malinowski, Luca Simione, Salvatore M. Aglioti, Antonino Raffone, Vasil Kolev

“…The emotional/cognitive appraisal of pain is reduced but remains preserved revealing a capacity of experienced meditators to dissociate pro-active and reactive top-down processes during pain control.…”
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Microbiome and metabolome reveal beneficial effects of baicalin on broiler growth performance and intestinal health by Xingbo Liu, Yunru Ji, Huiyuan Lv, Zengpeng Lv, Yuming Guo, Wei Nie

“…Metabolomics analysis revealed that BA improved the metabolic characteristics of intestinal mucosa, significantly upregulating pathways associated with ascorbate and aldarate metabolism, glyoxylate and dicarboxylate metabolism, phosphatidylinositol signaling system, alpha-linolenic acid metabolism, and galactose metabolism. 16S rRNA sequencing results indicated that BA increased the richness of intestinal microbiota community and the relative abundance of Actinobacteria phylum, while reducing the relative abundance of contains mobile elements, potentially pathogenic, and facultatively anaerobic. …”
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Revealing the role of RAB27 in HER receptor family expression and signaling in melanoma cells by Katarzyna Horodecka, Liliana Czernek, Łukasz Pęczek, Magdalena Klink

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Genetic mapping reveals Nfkbid as a central regulator of humoral immunity to Toxoplasma gondii. by Scott P Souza, Samantha D Splitt, Juan C Sànchez-Arcila, Julia A Alvarez, Jessica N Wilson, Safuwra Wizzard, Zheng Luo, Nicole Baumgarth, Kirk D C Jensen

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