Cross‐species chemogenomic profiling reveals evolutionarily conserved drug mode of action by Laura Kapitzky, Pedro Beltrao, Theresa J Berens, Nadine Gassner, Chunshui Zhou, Arthur Wüster, Julie Wu, M Madan Babu, Stephen J Elledge, David Toczyski, R Scott Lokey, Nevan J Krogan

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Drifter Observations Reveal Intense Vertical Velocity in a Surface Ocean Front by Daniel R. Tarry, Simón Ruiz, T. M. Shaun Johnston, Pierre‐Marie Poulain, Tamay Özgökmen, Luca R. Centurioni, Maristella Berta, Giovanni Esposito, J. Thomas Farrar, Amala Mahadevan, Ananda Pascual

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Trichuris trichiura egg extract proteome reveals potential diagnostic targets and immunomodulators. by Katalina Cruz, Antonio Marcilla, Patrick Kelly, Michel Vandenplas, Antonio Osuna, María Trelis

“…A total of 231 proteins were identified, 168 of them with known molecular functions. The proteome revealed common proteins families which are known to play roles in energy and metabolism; the cytoskeleton, muscle and motility; proteolysis; signaling; the stress response and detoxification; transcription and translation; and lipid binding and transport. …”
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A human neuron Alzheimer’s disease model reveals barriers to senolytic translatability by Chaska C. Walton, Ellen Wang, Suckwon Lee, Cynthia J. Siebrand, Nicholas J. Bergo, Zachary Mayeri, Julie K. Andersen

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Genome-wide analysis reveals a complex pattern of genomic imprinting in mice. by Jason B Wolf, James M Cheverud, Charles Roseman, Reinmar Hager

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Single-cell transcriptomics reveals an abnormal immune microenvironment in plasma cell mastitis by Qingtao Ni, Gaohua Han, Chi Pan

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Microbiome analysis reveals gut bacterial alterations in adult Tibetan pigs with diarrhea by Zhoulin Wu, Xiaoyu Li, Yan Wang, Jiamin Zhang, Lili Ji, Ling Gan

“…The differentially enriched pathways in the case and control pigs further revealed that gut dysbiosis exacerbated immune and inflammatory responses to promote the development of diarrhea. …”
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Virtual Smoke Signals: How VR Reveals the Unexpected Effects of Antitobacco Advertising by Solenne Bonneterre, Oulmann Zerhouni, Maréva Barré, Reinout Wiers, Marilisa Boffo

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Computational modelling reveals neurobiological contributions to static and dynamic functional connectivity patterns by Linnea Hoheisel, Linnea Hoheisel, Hannah Hacker, Gereon R Fink, Gereon R Fink, Silvia Daun, Silvia Daun, Joseph Kambeitz, Joseph Kambeitz

“…Perturbation analysis revealed that the sFC fit was most impacted by coupling changes in the left paracentral gyrus (Δr = 0.07), TC fit by alterations in the left pars triangularis (Δr = 0.24).Our findings indicate that neurobiological characteristics are associated with individual variability in sFC and dFC, and that sFC and dFC are shaped by small sets of distinct regions. …”
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Transcriptomic Profiling Reveals Key Genes Underlying Cold Stress Responses in Camphora by Bowen Shi, Linlin Zheng, Yifeng Wang, Qirui Wang

“…This study seeks to elucidate the molecular basis of cold tolerance through comparative transcriptomic analysis complemented by physiological characterization. RNA sequencing revealed 6123 differentially expressed genes between the two species, with enriched pathways related to cold stress, oxidative stress, carotenoid biosynthesis, and photosynthesis. …”
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SDG space: Revealing the structure and complementarities among sustainable development goals in China by Mimi Gong, Ke Yu, Changchang Zhou, Zhouyi Liu, Zhenci Xu, Ming Xu, Shen Qu

“…Historical data confirm that in the ‘SDG Space’ network, a goal connected to other well-developed goals would enjoy better future growth and vice versa. The structure reveals that SDG 4 (Quality Education), 15 (Life on Land), and 1 (No Poverty) are critical goals with transformative synergies to other SDGs. …”
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Shallow Tectonic Tremors Reveal the Beginning of the Slab Window at the Chilean Triple Junction by Kellen Azúa, Satoshi Ide, Seiya Yano, Sergio Ruiz, Hiroko Sugioka, Hajime Shiobara, Aki Ito, Matthew Miller, Hikaru Iwamori

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Metabolomics reveals the size effect of microplastics impeding membrane synthesis in rice cells by Zhenlong Yang, Xiao Xiao, Ting Liu, Haodong Wang, Xubiao Luo

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Revealing Unmapped Tectonic Settings through Geochemical Fingerprinting of Th-Nb-Yb by Huan Li, Shaban Godang, Sugeng Purwo Saputro

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Genetic transcriptional regulation profiling of cartilage reveals pathogenesis of osteoarthritisResearch in context by Wen Tian, Shan-Shan Dong, Feng Jiang, Jun-Qi Zhang, Chen Wang, Chang-Yi He, Shou-Ye Hu, Ruo-Han Hao, Hui-Miao Song, Hui-Wu Gao, Ke An, Dong-Li Zhu, Zhi Yang, Yan Guo, Tie-Lin Yang

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Revealing the differences in bicycle theft and motorcycle theft: spatial patterns and contributing factors by Lin Liu, Heng Liu, Dongping Long, Xinhua Huang

“…Abstract There exists abundant literature on vehicle theft, but only a few studies focused on bicycle theft and motorcycle theft. This study aims to reveal and explain differences in spatial distributions of bicycle theft and motorcycle theft in ZG city, China. …”
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Metabolome and Transcriptome Analyses Revealing the Molecular Mechanisms of Precarious Fertility in Quinoa Cultivars by Chao Song, Qingyun Huang, Chunsong Lin, Huihua Li, Ziyang Li, Yiding Xu, Fei Chen, Xueqin Zhang, Zhiqiang Wu, Suxia Xu

“…Phytohormone profiling yielded 60 metabolites and revealed the clear separation between different ecotypes at different developmental stages according to principal component analysis (PCA). …”
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Single-cell analysis reveals a longitudinal trajectory of meningioma evolution and heterogeneity by Ji Yoon Lee, Eun Jung Lee, Bo Yeon Seo, Jiwon Kim, Youjin Song, Dayoung Lee, Namsung Moon, Harim Koo, Chul-Kee Park, Min-Sung Kim, Serk In Park, Do-Hyun Nam, Doo-Sik Kong, Jason K. Sa

“…Tumor microenvironment analysis further reveals enrichments of COL6A3-mediated interactions between immunosuppressive macrophages and tumor cells in recurrent meningiomas. …”
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Transcriptomics reveals the underlying mechanism of Prostaglandin E1 in improving severe pneumonia by Wentong Ma, Jingxin Zhou, Ying Qian, Su Zhang, Chuanlu Han, Jing Su, Haijun Sun

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Individual plant genetics reveal the control of local adaptation in European maize landraces by Leke Victor Aiyesa, Dietrich Kaufmann, Birgit Zumbach, Wolfgang Link, Stefan Scholten, Timothy Beissinger

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